LM-94 (BioDeep_00000860368)
Main id: BioDeep_00000398406
PANOMIX_OTCML-2023
代谢物信息卡片
5-18-01-00439 (Beilstein Handbook Reference)
化学式: C10H8O3 (176.0473418)
中文名称: 4-甲基伞形酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)O
InChI: InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3
描述信息
A - Alimentary tract and metabolism > A05 - Bile and liver therapy > A05A - Bile therapy
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
C78272 - Agent Affecting Nervous System > C29698 - Antispasmodic Agent
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.
4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.
同义名列表
86 个代谢物同义名
5-18-01-00439 (Beilstein Handbook Reference); 2H-1-Benzopyren-2-one, 7-hydroxy-4-methyl-; 2H-1-Benzopyran, 7-hydroxy-4-methyl-2-oxo-; 2H-1-Benzopyran-2-one, 7-hydroxy-4-methyl-; 7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran; 7-Hydroxy-4-methyl-2H-chromen-2-one; 7-Hydroxy-4-methyl-2H-2-chromenone; 7-hydroxy-4-methyl-chromen-2-one; 7-hydroxy-4-methyl-2-chromenone; 7-hydroxy-4-methylchromen-2-one; Coumarin, 7-hydroxy-4-methyl-; 4-Methylumbelliferon [Czech]; 7-hydroxy-4-methyl-coumarin; Hymecromone (JP15\USAN\INN); Hymecromone [USAN:INN:JAN]; .beta.-Methylumbelliferone; 7-HYDROXY-4-METHYLCOUMARIN; 4-Methyl-7-hydroxycoumarin; METHYLUMBELLIFERONE, BETA; Himecromona [INN-Spanish]; Hymecromonum [INN-Latin]; beta-Methylumbelliferone; nchembio.2007.28-comp4; 4-Methyl-umbelliferone; 4-Methylumbelliferone; 4-Methylumbelliferon; WLN: T66 BOVJ E1 IQ; Prestwick1_000901; Prestwick2_000901; Prestwick3_000901; Imecromone [DCIT]; Prestwick0_000901; Maybridge1_002078; EINECS 201-986-7; Cantabiline (TN); SR-01000637483-1; NCGC00016345-01; BPBio1_000818; MEGxp0_001898; BSPBio_000742; ACon1_002401; ZINC00058121; NCI60_042099; MLS001074671; SPBio_002941; SMR000471886; M1381_SIGMA; Cantabiline; Cholonerton; 69580_FLUKA; CHEBI:17224; BRN 0142217; AIDS-018190; Hymecromone; CAS-90-33-5; 56275-29-7; Coumarin 4; AIDS018190; Hymecromon; Cumarote-C; CCRIS 5926; Cantabilin; Imecromone; AI3-08085; Bilicante; SBB009085; Omega 127; Mendiaxon; Cholestil; NSC 19026; Pilot 447; NSC 9408; Bilcolic; Eurogale; Crodimon; NSC19026; 90-33-5; CPD-182; NSC9408; Medilla; D00170; C03081; LM 94; LM-94; 4-MU; 4-Methylumbelliferone
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:17224
- KEGG: C03081
- PubChem: 5280567
- DrugBank: DB07118
- ChEMBL: CHEMBL12208
- MeSH: Hymecromone
- CAS: 1569304-40-0
- CAS: 79566-13-5
- CAS: 90-33-5
- PubChem: 5979
- PDB-CCD: 4MU
- 3DMET: B00538
- NIKKAJI: J3.914D
- medchemexpress: HY-N0187
- KNApSAcK: 17224
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 450027 - Dalbergia monetaria: 10.1016/0031-9422(83)80186-1
- 1544813 - Dalbergia volubilis: 10.1016/0031-9422(83)80186-1
- 1271630 - Ferula fukanensis: 10.1021/NP030408K
- 33090 - Plants: -
- 80276 - 乳香: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Noreen Halimani, Mikhail Nesterchuk, Alexandra A Tsitrina, Marat Sabirov, Irina N Andreichenko, Nataliya O Dashenkova, Elizaveta Petrova, Alexey M Kulikov, Timofei S Zatsepin, Roman A Romanov, Arsen S Mikaelyan, Yuri V Kotelevtsev. Knockdown of Hyaluronan synthase 2 suppresses liver fibrosis in mice via induction of transcriptomic changes similar to 4MU treatment.
Scientific reports.
2024 02; 14(1):2797. doi:
10.1038/s41598-024-53089-x. [PMID: 38307876] - Alexandra A Tsitrina, Noreen Halimani, Irina N Andreichenko, Marat Sabirov, Mikhail Nesterchuk, Nataliya O Dashenkova, Roman Romanov, Elena V Bulgakova, Arsen Mikaelyan, Yuri Kotelevtsev. 4-Methylumbelliferone Targets Revealed by Public Data Analysis and Liver Transcriptome Sequencing.
International journal of molecular sciences.
2023 Jan; 24(3):. doi:
10.3390/ijms24032129. [PMID: 36768453] - Joelle I Rosser, Nadine Nagy, Riya Goel, Gernot Kaber, Sally Demirdjian, Jamie Saxena, Jennifer B Bollyky, Adam R Frymoyer, Ana E Pacheco-Navarro, Elizabeth B Burgener, Jayakumar Rajadas, Zhe Wang, Olga Arbach, Colleen E Dunn, Anissa Kalinowski, Carlos E Milla, Paul L Bollyky. Oral hymecromone decreases hyaluronan in human study participants.
The Journal of clinical investigation.
2022 05; 132(9):. doi:
10.1172/jci157983. [PMID: 35499083] - Shuai Yang, Yun Ling, Fang Zhao, Wei Li, Zhigang Song, Lu Wang, Qiuting Li, Mengxing Liu, Ying Tong, Lu Chen, Daoping Ru, Tongsheng Zhang, Kaicheng Zhou, Baolong Zhang, Peng Xu, Zhicong Yang, Wenxuan Li, Yuanlin Song, Jianqing Xu, Tongyu Zhu, Fei Shan, Wenqiang Yu, Hongzhou Lu. Hymecromone: a clinical prescription hyaluronan inhibitor for efficiently blocking COVID-19 progression.
Signal transduction and targeted therapy.
2022 03; 7(1):91. doi:
10.1038/s41392-022-00952-w. [PMID: 35304437] - Rachel E Carlisle, Zahraa Mohammed-Ali, Chao Lu, Tamana Yousof, Victor Tat, Samera Nademi, Melissa E MacDonald, Richard C Austin, Jeffrey G Dickhout. TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease.
Cell death & disease.
2021 10; 12(10):921. doi:
10.1038/s41419-021-04197-3. [PMID: 34625532] - Jing Chen, Jialin Meng, Chen Jin, Fan Mo, Yang Ding, Xiaomei Gao, Li Zhang, Meng Zhang, Chaozhao Liang. 4-Methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy for chronic prostatitis.
The Prostate.
2021 10; 81(14):1078-1090. doi:
10.1002/pros.24205. [PMID: 34320251] - Alexandra A Tsitrina, Igor V Krasylov, Dmitry I Maltsev, Irina N Andreichenko, Viktoria S Moskvina, Dmitry N Ivankov, Elena V Bulgakova, Mikhail Nesterchuk, Vera Shashkovskaya, Nataliya O Dashenkova, Vladimir P Khilya, Arsen Mikaelyan, Yuri Kotelevtsev. Inhibition of hyaluronan secretion by novel coumarin compounds and chitin synthesis inhibitors.
Glycobiology.
2021 09; 31(8):959-974. doi:
10.1093/glycob/cwab038. [PMID: 33978736] - Yoon Mee Yang, Zhijun Wang, Michitaka Matsuda, Ekihiro Seki. Inhibition of hyaluronan synthesis by 4-methylumbelliferone ameliorates non-alcoholic steatohepatitis in choline-deficient L-amino acid-defined diet-induced murine model.
Archives of pharmacal research.
2021 Feb; 44(2):230-240. doi:
10.1007/s12272-021-01309-7. [PMID: 33486695] - Yanshan Zhong, Xiaodan Lu, Zhiwei Deng, Ziqing Lu, Minghui Fu. A 1232 bp upstream sequence of glutamine synthetase 1b from Eichhornia crassipes is a root-preferential promoter sequence.
BMC plant biology.
2021 Jan; 21(1):66. doi:
10.1186/s12870-021-02832-x. [PMID: 33514320] - Yang-Liu Xia, Jing-Jing Wang, Shi-Yang Li, Yong Liu, Frank J Gonzalez, Ping Wang, Guang-Bo Ge. Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment.
Bioorganic & medicinal chemistry.
2021 01; 29(?):115851. doi:
10.1016/j.bmc.2020.115851. [PMID: 33218896] - Pramod C Nair, Nuy Chau, Ross A McKinnon, John O Miners. Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity.
Molecular pharmacology.
2020 12; 98(6):710-718. doi:
10.1124/molpharm.120.000104. [PMID: 33008919] - Yixuan Li, Weihua Zhang, Tingting Yin, Ce Wang, Feige Wang, Jing Sun, Lina Liu, Qinghuai Zhang, Chunze Zhang. Inhibition of UDP-glucuronosyltransferases by different furoquinoline alkaloids.
Xenobiotica; the fate of foreign compounds in biological systems.
2020 Oct; 50(10):1170-1179. doi:
10.1080/00498254.2020.1760400. [PMID: 32367776] - Thea B Strøm, Terje Vinje, Katrine Bjune, Luís T da Costa, Jon K Laerdahl, Trond P Leren. Lysosomal acid lipase does not have a propeptide and should not be considered being a proprotein.
Proteins.
2020 03; 88(3):440-448. doi:
10.1002/prot.25821. [PMID: 31587363] - Yi Cao, Laia Herrero-Nogareda, Nina Cedergreen. A comparative study of acetylcholinesterase and general-esterase activity assays using different substrates, in vitro and in vivo exposures and model organisms.
Ecotoxicology and environmental safety.
2020 Feb; 189(?):109954. doi:
10.1016/j.ecoenv.2019.109954. [PMID: 31759743] - Irina N Andreichenko, Alexandra A Tsitrina, Alexander V Fokin, Adelya I Gabdulkhakova, Dmitry I Maltsev, Grigorii S Perelman, Elena V Bulgakova, Alexey M Kulikov, Arsen S Mikaelyan, Yuri V Kotelevtsev. 4-methylumbelliferone Prevents Liver Fibrosis by Affecting Hyaluronan Deposition, FSTL1 Expression and Cell Localization.
International journal of molecular sciences.
2019 Dec; 20(24):. doi:
10.3390/ijms20246301. [PMID: 31847129] - Jennifer L McKimm-Breschkin, Susan Barrett, Charley McKenzie-Kludas, Julie McAuley, Victor A Streltsov, Stephen G Withers. Passaging of an influenza A(H1N1)pdm09 virus in a difluoro sialic acid inhibitor selects for a novel, but unfit I106M neuraminidase mutant.
Antiviral research.
2019 09; 169(?):104542. doi:
10.1016/j.antiviral.2019.104542. [PMID: 31233807] - Yoon Mee Yang, Mazen Noureddin, Cheng Liu, Koichiro Ohashi, So Yeon Kim, Divya Ramnath, Elizabeth E Powell, Matthew J Sweet, Yoon Seok Roh, I-Fang Hsin, Nan Deng, Zhenqiu Liu, Jiurong Liang, Edward Mena, Daniel Shouhed, Robert F Schwabe, Dianhua Jiang, Shelly C Lu, Paul W Noble, Ekihiro Seki. Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis.
Science translational medicine.
2019 06; 11(496):. doi:
10.1126/scitranslmed.aat9284. [PMID: 31189722] - Nadine Nagy, Irina Gurevich, Hedwich F Kuipers, Shannon M Ruppert, Payton L Marshall, Bryan J Xie, Wenchao Sun, Andrey V Malkovskiy, Jayakumar Rajadas, Maria Grandoch, Jens W Fischer, Adam R Frymoyer, Gernot Kaber, Paul L Bollyky. 4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition.
The Journal of biological chemistry.
2019 05; 294(19):7864-7877. doi:
10.1074/jbc.ra118.006166. [PMID: 30914479] - Abel Suarez-Fueyo, Maria G Tsokos, Seung-Ki Kwok, Kayaho Maeda, Eri Katsuyama, Peter H Lapchak, George C Tsokos. Hyaluronic Acid Synthesis Contributes to Tissue Damage in Systemic Lupus Erythematosus.
Frontiers in immunology.
2019; 10(?):2172. doi:
10.3389/fimmu.2019.02172. [PMID: 31572382] - Dan-Dan Tian, Joshua J Kellogg, Neşe Okut, Nicholas H Oberlies, Nadja B Cech, Danny D Shen, Jeannine S McCune, Mary F Paine. Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation.
Drug metabolism and disposition: the biological fate of chemicals.
2018 05; 46(5):552-560. doi:
10.1124/dmd.117.079491. [PMID: 29467215] - Xia Lv, Jian-Bin Zhang, Xin-Xin Wang, Wen-Zhong Hu, Yu-Sheng Shi, Shu-Wen Liu, Da-Cheng Hao, Wei-Dong Zhang, Guang-Bo Ge, Jie Hou, Ling Yang. Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases.
Chemico-biological interactions.
2018 Mar; 284(?):48-55. doi:
10.1016/j.cbi.2018.02.009. [PMID: 29470958] - Sara Stridh, Fredrik Palm, Tomoko Takahashi, Mayumi Ikegami-Kawai, Malou Friederich-Persson, Peter Hansell. Hyaluronan Production by Renomedullary Interstitial Cells: Influence of Endothelin, Angiotensin II and Vasopressin.
International journal of molecular sciences.
2017 Dec; 18(12):. doi:
10.3390/ijms18122701. [PMID: 29236055] - Y-H Gong, G-M Ai, M Li, X-Y Shi, Q-Y Diao, X-W Gao. Functional characterization of carboxylesterase gene mutations involved in Aphis gossypii resistance to organophosphate insecticides.
Insect molecular biology.
2017 12; 26(6):702-714. doi:
10.1111/imb.12331. [PMID: 28799241] - Jeroen van Smeden, Irini M Dijkhoff, Richard W J Helder, Hanin Al-Khakany, Daphne E C Boer, Anne Schreuder, Wouter W Kallemeijn, Samira Absalah, Herman S Overkleeft, Johannes M F G Aerts, Joke A Bouwstra. In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling.
Journal of lipid research.
2017 12; 58(12):2299-2309. doi:
10.1194/jlr.m079376. [PMID: 29025868] - Jin-Shuai Lan, Yue Ding, Yun Liu, Ping Kang, Jian-Wei Hou, Xin-Yu Zhang, Sai-Sai Xie, Tong Zhang. Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease.
European journal of medicinal chemistry.
2017 Oct; 139(?):48-59. doi:
10.1016/j.ejmech.2017.07.055. [PMID: 28797883] - Claire Grignon, Antoine Dupuis, Marion Albouy-Llaty, Maxime Condylis, Laurence Barrier, Pascal Carato, Bertrand Brunet, Virginie Migeot, Nicolas Venisse. Validation of a probe for assessing deconjugation of glucuronide and sulfate phase II metabolites assayed through LC-MS/MS in biological matrices.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Sep; 1061-1062(?):72-78. doi:
10.1016/j.jchromb.2017.07.013. [PMID: 28710970] - Guang Xian Pang, Chao Niu, Nuramina Mamat, Haji Akber Aisa. Synthesis and in vitro biological evaluation of novel coumarin derivatives containing isoxazole moieties on melanin synthesis in B16 cells and inhibition on bacteria.
Bioorganic & medicinal chemistry letters.
2017 06; 27(12):2674-2677. doi:
10.1016/j.bmcl.2017.04.039. [PMID: 28476568] - Xin Liu, Yun-Feng Cao, Pei-Pei Dong, Liang-Liang Zhu, Zhenying Zhao, Xue Wu, Zhi-Wei Fu, Chun-Ting Huang, Zhong-Ze Fang, Hong-Zhi Sun. The inhibition of UDP-glucuronosyltransferases (UGTs) by vitamin A.
Xenobiotica; the fate of foreign compounds in biological systems.
2017 May; 47(5):376-381. doi:
10.1080/00498254.2016.1198841. [PMID: 27359323] - H F Kuipers, N Nagy, S M Ruppert, V G Sunkari, P L Marshall, J A Gebe, H D Ishak, S G Keswani, J Bollyky, A R Frymoyer, T N Wight, L Steinman, P L Bollyky. The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice.
Clinical and experimental immunology.
2016 09; 185(3):372-81. doi:
10.1111/cei.12815. [PMID: 27218304] - Si Liu, Anna Kulinich, Zhi P Cai, Hong Y Ma, Ya M Du, Yong M Lv, Li Liu, Josef Voglmeir. The fucosidase-pool of Emticicia oligotrophica: Biochemical characterization and transfucosylation potential.
Glycobiology.
2016 08; 26(8):871-879. doi:
10.1093/glycob/cww030. [PMID: 26941394] - . Pancreatic lipase and α-amylase inhibitory activities of plants used in Traditional Chinese Medicine (TCM).
Die Pharmazie.
2016 Jul; 71(7):420-424. doi:
10.1691/ph.2016.6569. [PMID: 29441920] - Xia Lv, Xin-Xin Wang, Jie Hou, Zhong-Ze Fang, Jing-Jing Wu, Yun-Feng Cao, Shu-Wen Liu, Guang-Bo Ge, Ling Yang. Comparison of the inhibitory effects of tolcapone and entacapone against human UDP-glucuronosyltransferases.
Toxicology and applied pharmacology.
2016 06; 301(?):42-9. doi:
10.1016/j.taap.2016.04.009. [PMID: 27089846] - F Tang, Y Xiong, H Zhang, K Wu, Y Xiang, J-B Shao, H-W Ai, Y-P Xiang, X-L Zheng, J-R Lv, H Sun, L-S Bao, Z Zhang, H-B Hu, J-Y Zhang, L Chen, J Lu, W-Y Liu, H Mei, Y Ma, C-F Xu, A-Y Fang, M Gu, C-Y Xu, Y Chen, Z Chen, Z-Y Sun. Visual detection technique for efficient screening and isolation of Salmonella based on a novel enrichment assay using chromatography membrane.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2016 Mar; 35(3):353-61. doi:
10.1007/s10096-015-2543-2. [PMID: 26796551] - Mingjie Tang, Yanjie Guo, Youshui Gao, Chao Tang, Xiaoqian Dang, Zubin Zhou, Yuqiang Sun, Kunzheng Wang. Albumin's Influence on Carprofen Enantiomers-Hymecromone Interaction.
Chirality.
2016 Mar; 28(3):226-9. doi:
10.1002/chir.22562. [PMID: 26708612] - Vivekanand Tiwari, Manish Kumar Patel, Amit Kumar Chaturvedi, Avinash Mishra, Bhavanath Jha. Functional Characterization of the Tau Class Glutathione-S-Transferases Gene (SbGSTU) Promoter of Salicornia brachiata under Salinity and Osmotic Stress.
PloS one.
2016; 11(2):e0148494. doi:
10.1371/journal.pone.0148494. [PMID: 26885663] - N V Olkhovych. Chitotriosidase activity as additional biomarker in the diagnosis of lysosomal storage diseases.
Ukrainian biochemical journal.
2016 Jan; 88(1):69-78. doi:
10.15407/ubj88.01.069. [PMID: 29227082] - Qian Zhang, Yun-Feng Cao, Rui-Xue Ran, Rong-Shan Li, Xue Wu, Pei-Pei Dong, Yan-Yan Zhang, Cui-Min Hu, Wei-Ming Wang. Strong Specific Inhibition of UDP-glucuronosyltransferase 2B7 by Atractylenolide I and III.
Phytotherapy research : PTR.
2016 Jan; 30(1):25-30. doi:
10.1002/ptr.5496. [PMID: 26536846] - Dan Liu, Jie Wu, Hongbo Xie, Mingyi Liu, Isaiah Takau, Hong Zhang, Yuqing Xiong, Chunhua Xia. Inhibitory Effect of Hesperetin and Naringenin on Human UDP-Glucuronosyltransferase Enzymes: Implications for Herb-Drug Interactions.
Biological & pharmaceutical bulletin.
2016; 39(12):2052-2059. doi:
10.1248/bpb.b16-00581. [PMID: 27904048] - Travis J Yates, Luis E Lopez, Soum D Lokeshwar, Nicolas Ortiz, Georgios Kallifatidis, Andre Jordan, Kelly Hoye, Norman Altman, Vinata B Lokeshwar. Dietary supplement 4-methylumbelliferone: an effective chemopreventive and therapeutic agent for prostate cancer.
Journal of the National Cancer Institute.
2015 Jul; 107(7):. doi:
10.1093/jnci/djv085. [PMID: 25868577] - Akihiro Ogawa, Toshiya Kobayashi, Fumihiko Sakai, Yukio Kadooka, Yoshihiro Kawasaki. Lactobacillus gasseri SBT2055 suppresses fatty acid release through enlargement of fat emulsion size in vitro and promotes fecal fat excretion in healthy Japanese subjects.
Lipids in health and disease.
2015 Mar; 14(?):20. doi:
10.1186/s12944-015-0019-0. [PMID: 25884980] - Jianbin Zhang, Yan Lv, Bing Wang, Shan Zhao, Mingqian Tan, Guojun Lv, Xiaojun Ma. Influence of microemulsion-mucin interaction on the fate of microemulsions diffusing through pig gastric mucin solutions.
Molecular pharmaceutics.
2015 Mar; 12(3):695-705. doi:
10.1021/mp500475y. [PMID: 25608210] - Brandon T Gufford, Gang Chen, Philip Lazarus, Tyler N Graf, Nicholas H Oberlies, Mary F Paine. Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation.
Drug metabolism and disposition: the biological fate of chemicals.
2014 Oct; 42(10):1675-83. doi:
10.1124/dmd.114.059451. [PMID: 25008344] - Mi-Ok Sim, Ju Ri Ham, Hae-In Lee, Kwon-Il Seo, Mi-Kyung Lee. Long-term supplementation of umbelliferone and 4-methylumbelliferone alleviates high-fat diet induced hypertriglyceridemia and hyperglycemia in mice.
Chemico-biological interactions.
2014 Jun; 216(?):9-16. doi:
10.1016/j.cbi.2014.03.003. [PMID: 24661945] - Jianbin Zhang, Yan Lv, Shan Zhao, Bing Wang, Mingqian Tan, Hongguo Xie, Guojun Lv, Xiaojun Ma. Effect of lipolysis on drug release from self-microemulsifying drug delivery systems (SMEDDS) with different core/shell drug location.
AAPS PharmSciTech.
2014 Jun; 15(3):731-40. doi:
10.1208/s12249-014-0096-9. [PMID: 24554238] - Aditya G Kohli, Heidi M Kieler-Ferguson, Darren Chan, Francis C Szoka. A robust and quantitative method for tracking liposome contents after intravenous administration.
Journal of controlled release : official journal of the Controlled Release Society.
2014 Feb; 176(?):86-93. doi:
10.1016/j.jconrel.2013.12.014. [PMID: 24368300] - Yan Fang, Hua Wang, Wenjuan Zhu, Lu Wang, Hengjiang Liu, Yue He, Xu Xu, Weimin Yin, Yanghu Sima, Shiqing Xu. Antioxidative capacity in the fat body of Bombyx mori is increased following oral administration of 4-methylumbelliferone.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2014 Jan; 159(?):31-7. doi:
10.1016/j.cbpc.2013.09.003. [PMID: 24080584] - Zhong-Ze Fang, Rong-Rong He, Yun-Feng Cao, Naoki Tanaka, Changtao Jiang, Kristopher W Krausz, Yunpeng Qi, Pei-Pei Dong, Chun-Zhi Ai, Xiao-Yu Sun, Mo Hong, Guang-Bo Ge, Frank J Gonzalez, Xiao-Chi Ma, Hong-Zhi Sun. A model of in vitro UDP-glucuronosyltransferase inhibition by bile acids predicts possible metabolic disorders.
Journal of lipid research.
2013 Dec; 54(12):3334-44. doi:
10.1194/jlr.m040519. [PMID: 24115227] - Sara Stridh, Fredrik Palm, Peter Hansell. Inhibition of hyaluronan synthesis in rats reduces renal ability to excrete fluid and electrolytes during acute hydration.
Upsala journal of medical sciences.
2013 Nov; 118(4):217-21. doi:
10.3109/03009734.2013.834013. [PMID: 24102146] - Vanessa Colombaro, Anne-Emilie Declèves, Inès Jadot, Virginie Voisin, Laetitia Giordano, Isabelle Habsch, Denis Nonclercq, Bruno Flamion, Nathalie Caron. Inhibition of hyaluronan is protective against renal ischaemia-reperfusion injury.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2013 Oct; 28(10):2484-93. doi:
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African health sciences.
2013 Sep; 13(3):556-9. doi:
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Carbohydrate research.
2013 Aug; 377(?):35-43. doi:
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Journal of ethnopharmacology.
2013 Jul; 148(3):980-7. doi:
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The Journal of urology.
2013 Jul; 190(1):285-90. doi:
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Die Pharmazie.
2013 Jun; 68(6):449-52. doi:
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Arthritis and rheumatism.
2013 May; 65(5):1160-70. doi:
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Brain & development.
2013 Apr; 35(4):317-22. doi:
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Toxicology and applied pharmacology.
2013 Mar; 267(2):149-54. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
2013 Feb; 43(2):133-9. doi:
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PloS one.
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PloS one.
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Drug metabolism and disposition: the biological fate of chemicals.
2012 Nov; 40(11):2192-203. doi:
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Applied microbiology and biotechnology.
2012 Jun; 94(5):1347-58. doi:
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The Journal of biological chemistry.
2012 May; 287(19):15966-80. doi:
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Annals of laboratory medicine.
2012 May; 32(3):184-9. doi:
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Journal of experimental botany.
2012 May; 63(8):2985-3000. doi:
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Laboratory animal research.
2012 Mar; 28(1):31-8. doi:
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Korean journal of pediatrics.
2012 Mar; 55(3):88-92. doi:
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BMC plant biology.
2012 Feb; 12(?):27. doi:
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Phytotherapy research : PTR.
2012 Jan; 26(1):86-90. doi:
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TheScientificWorldJournal.
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Experimental diabetes research.
2012; 2012(?):231502. doi:
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Journal of environmental and public health.
2012; 2012(?):185731. doi:
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PloS one.
2012; 7(3):e33286. doi:
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Protein expression and purification.
2012 Jan; 81(1):69-74. doi:
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Frontiers in plant science.
2012; 3(?):80. doi:
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Molecular biology of the cell.
2011 Dec; 22(23):4635-46. doi:
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Journal of physiology and biochemistry.
2011 Dec; 67(4):569-76. doi:
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BMC plant biology.
2011 Nov; 11(?):152. doi:
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Plant signaling & behavior.
2011 Nov; 6(11):1654-5. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2011 Nov; 39(11):2117-29. doi:
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Journal of experimental botany.
2011 Nov; 62(15):5463-9. doi:
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Journal of neuroinflammation.
2011 Oct; 8(?):144. doi:
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BMC plant biology.
2011 Sep; 11(?):129. doi:
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Anticancer research.
2011 Sep; 31(9):2915-22. doi:
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Journal of chemical ecology.
2011 Aug; 37(8):880-90. doi:
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The protein journal.
2011 Aug; 30(6):367-73. doi:
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BMC biotechnology.
2011 Jul; 11(?):74. doi:
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Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2011 Jun; 34(6):901-4. doi:
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Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2011 May; 63(4):325-30. doi:
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BMC cell biology.
2011 Apr; 12(?):16. doi:
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The Journal of pharmacy and pharmacology.
2011 Apr; 63(4):507-14. doi:
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Veterinary research.
2011 Mar; 42(?):49. doi:
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The Plant cell.
2011 Mar; 23(3):1153-70. doi:
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Molecular pharmacology.
2011 Mar; 79(3):472-8. doi:
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Molecular plant.
2011 Mar; 4(2):300-9. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2011 Feb; 39(2):322-9. doi:
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Pharmacogenetics and genomics.
2011 Feb; 21(2):55-65. doi:
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International journal of molecular sciences.
2011; 12(5):2808-21. doi:
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PloS one.
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