Aloeemodin (BioDeep_00000859686)

PANOMIX_OTCML-2023

代谢物信息卡片

InChI=1\C15H10O5\c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17\h1-5,16-18H,6H

化学式: C15H10O5 (270.052821)
中文名称: 芦荟大黄素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO
InChI: InChI=1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2

描述信息

Aloe emodin is a hydroxyanthraquinone extracted from aloe leaves and has been shown to have anti-tumor activity in vitro and in vivo.
Aloe emodin is a hydroxyanthraquinone extracted from aloe leaves and has been shown to have anti-tumor activity in vitro and in vivo.

同义名列表

36 个代谢物同义名

InChI=1\C15H10O5\c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17\h1-5,16-18H,6H; 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)- (9CI); 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)-; 1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione; 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione; 1,8-Dihydroxy-3-(hydroxymethyl)anthra-9,10-quinone; Anthraquinone, 1,8-dihydroxy-3-(hydroxymethyl)-; ANTHRAQUINONE, 1,8-DIHYDROXY-3-HYDROXYMETHYL-; 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone; 4-08-00-03578 (Beilstein Handbook Reference); 1,8-dihydroxy-3-hydroxymethyl-anthraquinone; 1,8-dihydroxy-3-methylol-9,10-anthraquinone; 1,8-Dihydroxy-3-hydroxymethylanthraquinone; 3-Hydroxymethylchrysazin; EINECS 207-571-7; NCGC00163510-02; NCGC00163510-01; aloe emodine; Rhabarberone; LMPK02000031; NCI60_003685; A7687_SIGMA; Aloe-emodin; Aloe emodin; BRN 2059062; AIDS-048396; SMP2_000291; CCRIS 3526; AIDS048396; Aloeemodin; NSC 38628; 481-72-1; NSC38628; EMODINE; C10294; 3-Hydroxymethylchrysazine

数据库引用编号

5 个数据库交叉引用编号

ChEBI: CHEBI:2607
PubChem: 10207
ChEMBL: CHEMBL40275
CAS: 481-72-1
medchemexpress: HY-N0189

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

155 个相关的物种来源信息

33090 猕猴桃根: -
33090 木蝴蝶: -
33090 鸡血藤: -
53851 决明子: -
33090 萱草根: -
33090 苍耳子: -
33090 薄荷: -
33090 大黄: -
33090 芦荟: -
72401 Senna didymobotrya:
34199 Aloe vera:
53923 Senna alata: 10.1002/(SICI)1099-1573(199808)12:5<324::AID-PTR300>3.0.CO;2-2
1389495 Aloe castellorum: 10.1080/14786410802242851
428217 Callisia fragrans: 10.1007/S10600-009-9174-8
508996 Cassia javanica: 10.21608/BFSA.1985.75705
346999 Senna siamea: 10.21608/BFSA.1985.75705
53852 Cassia fistula: 10.21608/BFSA.1985.75705
992784 Senna petersiana: 10.1016/S0367-326X(00)00155-6
72402 Senna alexandrina:
346985 Senna obtusifolia:
126820 Senna occidentalis: 10.1016/S0031-9422(01)00114-5
362788 Senna tora: 10.1016/S0031-9422(01)00114-5
948715 Chamaecrista mimosoides: 10.1016/S0031-9422(01)00114-5
53851 Cassia: 10.1016/S0031-9422(01)00114-5
240184 Rheum spiciforme: 10.1016/0378-8741(84)90016-3
137224 Rheum reticulatum: 10.1016/0378-8741(84)90016-3
284362 Rheum alexandrae: 10.1016/0378-8741(84)90016-3
694413 Rheum delavayi: 10.1016/0378-8741(84)90016-3
137223 Rheum pumilum: 10.1016/0378-8741(84)90016-3
205071 Rheum tataricum: 10.1016/0378-8741(84)90016-3
694412 Rheum acuminatum: 10.1016/0378-8741(84)90016-3
2743666 Rheum racemiferum: 10.1016/0378-8741(84)90016-3
137228 Rheum wittrockii: 10.1016/0378-8741(84)90016-3
137216 Rheum compactum: 10.1016/0378-8741(84)90016-3
46087 Rheum rhaponticum:
3621 Rheum rhabarbarum:
137227 Rheum undulatum:
137697 Rheum nobile: 10.1016/0378-8741(84)90016-3
137218 Rheum likiangense: 10.1016/0378-8741(84)90016-3
240182 Rheum franzenbachii:
574896 Rheum altaicum: 10.1016/0378-8741(84)90016-3
240183 Rheum kialense: 10.1016/0378-8741(84)90016-3
137217 Rheum hotaoense: 10.1016/0378-8741(84)90016-3
284363 Rheum australe:
137221 Rheum palmatum:
137226 Rheum tanguticum:
137220 Rheum officinale:
3610 Rhamnus cathartica: 10.1076/PHBI.38.5.321.5965
1129486 Picramnia antidesma:
25641 Aloe:
2686326 Picramnia hirsuta: 10.1016/S0031-9422(98)00383-5
278676 Rumex cristatus: 10.1042/BJ0980112
242528 Rumex scutatus: 10.1515/ZNC-1997-9-1014
555937 Kniphofia ensifolia: 10.1016/J.BMC.2013.11.032
3620 Rheum:
3618 Rumex: 10.1016/J.BMCL.2013.04.059
214843 Kniphofia schimperi: 10.1016/0031-9422(86)80014-0
214840 Kniphofia insignis: 10.1016/0031-9422(86)80014-0
214838 Kniphofia foliosa:
214841 Kniphofia isoetifolia: 10.1016/0031-9422(86)80014-0
1353961 Selaginella delicatula: 10.1007/S10600-011-0013-3
1226760 Berchemia floribunda: 10.1248/CPB.56.1248
1128810 Aloe succotrina: 10.1515/ZNC-1994-5-602
117798 Aloe ferox: 10.1016/S0031-9422(00)89546-1
72655 Xanthorrhoea australis: 10.1071/CH9740331
162709 Cassia grandis: 10.1055/S-2006-957847
45385 Aloe arborescens:
346994 Senna reticulata:
455371 Spatholobus suberectus: 10.1002/HLCA.200690121
49698 Asphodelus aestivus: 10.1016/S0031-9422(00)90193-6
1423376 Asphodelus tenuifolius: 10.1016/S0031-9422(00)90193-6
1497607 Asphodelus fistulosus:
221659 Asphodelus ramosus: 10.1016/S0031-9422(00)90193-6
280017 Rhamnus alaternus: 10.1039/JR9530003069
105902 Rhamnus davurica: 10.1039/JR9530003069
207931 Asphodelus albus: 10.1055/S-0028-1097723
1813113 Aloe elgonica: 10.1021/NP50071A038
3615 Polygonaceae: 10.1021/ACS.JNATPROD.7B00799.S001
72401 Senna didymobotrya:
34199 Aloe vera:
53923 Senna alata: 10.1002/(SICI)1099-1573(199808)12:5<324::AID-PTR300>3.0.CO;2-2
1389495 Aloe castellorum: 10.1080/14786410802242851
428217 Callisia fragrans: 10.1007/S10600-009-9174-8
508996 Cassia javanica: 10.21608/BFSA.1985.75705
346999 Senna siamea: 10.21608/BFSA.1985.75705
53852 Cassia fistula: 10.21608/BFSA.1985.75705
992784 Senna petersiana: 10.1016/S0367-326X(00)00155-6
72402 Senna alexandrina:
346985 Senna obtusifolia:
126820 Senna occidentalis: 10.1016/S0031-9422(01)00114-5
362788 Senna tora: 10.1016/S0031-9422(01)00114-5
948715 Chamaecrista mimosoides: 10.1016/S0031-9422(01)00114-5
53851 Cassia: 10.1016/S0031-9422(01)00114-5
240184 Rheum spiciforme: 10.1016/0378-8741(84)90016-3
137224 Rheum reticulatum: 10.1016/0378-8741(84)90016-3
284362 Rheum alexandrae: 10.1016/0378-8741(84)90016-3
694413 Rheum delavayi: 10.1016/0378-8741(84)90016-3
137223 Rheum pumilum: 10.1016/0378-8741(84)90016-3
205071 Rheum tataricum: 10.1016/0378-8741(84)90016-3
694412 Rheum acuminatum: 10.1016/0378-8741(84)90016-3
2743666 Rheum racemiferum: 10.1016/0378-8741(84)90016-3
137228 Rheum wittrockii: 10.1016/0378-8741(84)90016-3
137216 Rheum compactum: 10.1016/0378-8741(84)90016-3
46087 Rheum rhaponticum:
3621 Rheum rhabarbarum:
137227 Rheum undulatum:
137697 Rheum nobile: 10.1016/0378-8741(84)90016-3
137218 Rheum likiangense: 10.1016/0378-8741(84)90016-3
240182 Rheum franzenbachii:
574896 Rheum altaicum: 10.1016/0378-8741(84)90016-3
240183 Rheum kialense: 10.1016/0378-8741(84)90016-3
137217 Rheum hotaoense: 10.1016/0378-8741(84)90016-3
284363 Rheum australe:
137221 Rheum palmatum:
137226 Rheum tanguticum:
137220 Rheum officinale:
3610 Rhamnus cathartica: 10.1076/PHBI.38.5.321.5965
1129486 Picramnia antidesma:
25641 Aloe:
2686326 Picramnia hirsuta: 10.1016/S0031-9422(98)00383-5
278676 Rumex cristatus: 10.1042/BJ0980112
242528 Rumex scutatus: 10.1515/ZNC-1997-9-1014
555937 Kniphofia ensifolia: 10.1016/J.BMC.2013.11.032
3620 Rheum:
3618 Rumex: 10.1016/J.BMCL.2013.04.059
214843 Kniphofia schimperi: 10.1016/0031-9422(86)80014-0
214840 Kniphofia insignis: 10.1016/0031-9422(86)80014-0
214838 Kniphofia foliosa:
214841 Kniphofia isoetifolia: 10.1016/0031-9422(86)80014-0
1353961 Selaginella delicatula: 10.1007/S10600-011-0013-3
1226760 Berchemia floribunda: 10.1248/CPB.56.1248
1128810 Aloe succotrina: 10.1515/ZNC-1994-5-602
117798 Aloe ferox: 10.1016/S0031-9422(00)89546-1
72655 Xanthorrhoea australis: 10.1071/CH9740331
162709 Cassia grandis: 10.1055/S-2006-957847
45385 Aloe arborescens:
346994 Senna reticulata:
455371 Spatholobus suberectus: 10.1002/HLCA.200690121
49698 Asphodelus aestivus: 10.1016/S0031-9422(00)90193-6
1423376 Asphodelus tenuifolius: 10.1016/S0031-9422(00)90193-6
1497607 Asphodelus fistulosus:
221659 Asphodelus ramosus: 10.1016/S0031-9422(00)90193-6
280017 Rhamnus alaternus: 10.1039/JR9530003069
105902 Rhamnus davurica: 10.1039/JR9530003069
207931 Asphodelus albus: 10.1055/S-0028-1097723
1813113 Aloe elgonica: 10.1021/NP50071A038
3615 Polygonaceae: 10.1021/ACS.JNATPROD.7B00799.S001
455371 Spatholobus Suberectus Dunn: -
25641 Aloe: -
3625 Actinidia Chinensis Planch: -
137221 Rheum palmatum L.: -
137226 Rheum tanguticum Maxim. ex Balf.: -
137220 Rheum officinale Baill.: -
4414 Euryale ferox Salisb.: -
33090 Plants: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Huang-Fei Jin, Qian-Xue Shen, Ying Shi, Fang-Ming Liu, Bin Wang, Jun Cao, Li-Hong Ye. Magnetic-stirring-enhanced mechanical amorphous dispersion extraction for the hydrophobic phytochemical constituents using an aqueous solution from a medicinal plant. Journal of pharmaceutical and biomedical analysis. 2024 Aug; 245(?):116191. doi: 10.1016/j.jpba.2024.116191. [PMID: 38728950]
Xun Li, Minghe Yao, Lingling Li, Huifen Ma, Yiran Sun, Xiangpeng Lu, Weipeng Jing, Shanshan Nie. Aloe-emodin alleviates cerebral ischemia-reperfusion injury by regulating microglial polarization and pyroptosis through inhibition of NLRP3 inflammasome activation. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155578. doi: 10.1016/j.phymed.2024.155578. [PMID: 38621328]
Jiali Wu, Yaokun Pang, Dan Liu, Jianxia Sun, Weibin Bai. Photodynamic Inactivation of Staphylococcus aureus Using Aloe-emodin as Photosensitizer. Food research international (Ottawa, Ont.). 2024 Feb; 178(?):113959. doi: 10.1016/j.foodres.2024.113959. [PMID: 38309912]
Fang Zhang, Rui Wu, Yanfang Liu, Shu Dai, Xinyan Xue, Xiaohong Gong, Yunxia Li. Comparative Pharmacokinetic Study of Rhubarb Anthraquinones in Normal and Nonalcoholic Fatty Liver Disease Rats. European journal of drug metabolism and pharmacokinetics. 2024 Jan; 49(1):111-121. doi: 10.1007/s13318-023-00875-z. [PMID: 38112917]
Huijuan Lv, Jingjing Niu, Wenhao Pan, Yudong Wang, Lifang Wang, Meng Wang, Yali Shi, Guifang Zhang, Bandar Al Hamyari, Shaohua Wang, Xuefeng Li, Yanbin Shi. Stool-softening effect and action mechanism of free anthraquinones extracted from Rheum palmatum L. on water deficit-induced constipation in rats. Journal of ethnopharmacology. 2023 Oct; 319(Pt 3):117336. doi: 10.1016/j.jep.2023.117336. [PMID: 37907143]
Martyna Nowak-Perlak, Piotr Ziółkowski, Marta Woźniak. A promising natural anthraquinones mediated by photodynamic therapy for anti-cancer therapy. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Oct; 119(?):155035. doi: 10.1016/j.phymed.2023.155035. [PMID: 37603973]
Meng Yu, Xin-Yu Kong, Tong-Tong Chen, Zhong-Mei Zou. In vivo metabolism combined network pharmacology to identify anti-constipation constituents in Aloe barbadensis Mill. Journal of ethnopharmacology. 2023 Sep; 319(Pt 1):117200. doi: 10.1016/j.jep.2023.117200. [PMID: 37726070]
Hanaa M Sayed, Mahmoud A Ramadan, Heba H Salem, Iqrar Ahmad, Harun Patel, Marwa A A Fayed. Phytochemical Investigation, In silico/In vivo Analgesic, and Anti-inflammatory Assessment of the Egyptian Cassia occidentalis L. Steroids. 2023 May; 196(?):109245. doi: 10.1016/j.steroids.2023.109245. [PMID: 37141980]
Si Li, Xi Wu, Yue Ma, Hua Zhang, Wen Chen. Prediction and verification of the active ingredients and potential targets of Erhuang Quzhi Granules on non-alcoholic fatty liver disease based on network pharmacology. Journal of ethnopharmacology. 2023 Apr; ?(?):116435. doi: 10.1016/j.jep.2023.116435. [PMID: 37023836]
Ya-Peng Liu, Wang Zhang, Xin-Jie Liu, Huan Wu, An Zhou. [Determination of complexation ability of rhubarb with copper ions by ultra-high performance liquid chromatography]. Se pu = Chinese journal of chromatography. 2023 Apr; 41(4):323-329. doi: 10.3724/sp.j.1123.2022.06020. [PMID: 37005919]
Fan Wu, Yan Wang, Quanxi Mei, Qinhua Chen, Chengpeng Sun, Xia Lv, Lei Feng, Chao Wang, Yanyan Zhang, Bangjiang Fang, Xiaokui Huo, Xiangge Tian, Xiaochi Ma. UGTs-mediated metabolic interactions contribute to enhanced anti-inflammation activity of Jinhongtang. Journal of ethnopharmacology. 2023 Mar; 304(?):116016. doi: 10.1016/j.jep.2022.116016. [PMID: 36535328]
Shanlin Chen, Xiaoxue Guan, Lei Xie, Chuanyu Liu, Chunhong Li, Min He, Jiahua Hu, Hui Fan, Quanwen Li, Liuping Xie, Mingqing Yang, Xiaoling Zhang, Shengjun Xiao, Jianhong Tang. Aloe-emodin targets multiple signaling pathways by blocking ubiquitin-mediated degradation of DUSP1 in nasopharyngeal carcinoma cells. Phytotherapy research : PTR. 2023 Mar; ?(?):. doi: 10.1002/ptr.7793. [PMID: 36866539]
Dongpeng Wang, Jufeng Duan, Xiao-Jing Chen, Kaiqi Liu, Yingying Guo, Run Shi, Sha Li, Ming Liu, Lijun Zhao, Bei Li, Hongtao Liu, Minglun Li, Yibin Feng, Hongliang Li, Xuanbin Wang. Pharmacokinetic characteristics of emodin in polygoni Multiflori Radix Praeparata. Journal of ethnopharmacology. 2023 Mar; 303(?):115945. doi: 10.1016/j.jep.2022.115945. [PMID: 36435407]
Ganesh Dakne, Mohamad Taleuzzaman, Mohammad Sarafroz, Pankaj Yadav, Yasmin Khatoon, Ziyaul Haque, Sufiyan Ahmad. Aloe-emodin quantification using HPTLC and RP-UHPLC in extracts and commercial herbal formulations: Evaluation of antimicrobial and antioxidant effects. Recent advances in anti-infective drug discovery. 2023 Feb; ?(?):. doi: 10.2174/2772434418666230222085606. [PMID: 36815640]
Lingling Wang, Guoying Zhou, Shuo Zhao, Yang Yang. Soluble protein content, bioactive compounds and the antioxidant activity in seeds of ten Rheum tanguticum lines from Qinghai-Tibet Plateau. Chemistry & biodiversity. 2023 Feb; ?(?):e202200901. doi: 10.1002/cbdv.202200901. [PMID: 36788177]
Guorong Cheng, Zhiqiang Liu, Zhong Zheng, Fengrui Song, Xiaoyu Zhuang, Shu Liu. Cell Metabolomics Reveals the Potential Mechanism of Aloe Emodin and Emodin Inhibiting Breast Cancer Metastasis. International journal of molecular sciences. 2022 Nov; 23(22):. doi: 10.3390/ijms232213738. [PMID: 36430215]
Hai Shang, Yue Hu, Jingrong Li, Lingyu Li, Yu Tian, Xiaoxue Li, Qi Wu, Zhongmei Zou. The Synthesis and Biological Evaluation of Aloe-Emodin-Coumarin Hybrids as Potential Antitumor Agents. Molecules (Basel, Switzerland). 2022 Sep; 27(19):. doi: 10.3390/molecules27196153. [PMID: 36234685]
Fan Wu, Baojing Zhang, Yu Zhang, Ting Zhao, Yan Wang, Xiangge Tian, Chengpeng Sun, Bangjiang Fang, Xiaokui Huo, Xiaochi Ma. Simultaneous Determination of Ten Active Components From Jinhongtang Granule in Rat Plasma by LC-MS/MS and its Application to a Comparative Pharmacokinetic Study in Normal and Sepsis Rats In Vivo and In Vitro. Journal of chromatographic science. 2022 Aug; ?(?):. doi: 10.1093/chromsci/bmac043. [PMID: 35913259]
Magdalena Westermann, Amma G Adomako-Bonsu, Solveig Thiele, Serhat Sezai Çiçek, Hans-Jörg Martin, Edmund Maser. Inhibition of human carbonyl reducing enzymes by plant anthrone and anthraquinone derivatives. Chemico-biological interactions. 2022 Feb; 354(?):109823. doi: 10.1016/j.cbi.2022.109823. [PMID: 35065925]
Ibrahim Morgan, Ludger A Wessjohann, Goran N Kaluđerović. In Vitro Anticancer Screening and Preliminary Mechanistic Study of A-Ring Substituted Anthraquinone Derivatives. Cells. 2022 01; 11(1):. doi: 10.3390/cells11010168. [PMID: 35011730]
Chwan-Fwu Lin, Shih-Yi Chuang, Tse-Hung Huang, Thi My Huyen Nguyen, Pei-Wen Wang, Ahmed Alalaiwe, Jia-You Fang. A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Jan; 145(?):112482. doi: 10.1016/j.biopha.2021.112482. [PMID: 34915669]
Yuan Zhou, Rong Wu, Fei-Fei Cai, Wen-Jun Zhou, Yi-Yu Lu, Hui Zhang, Qi-Long Chen, Ming-Yu Sun, Shi-Bing Su. Development of a novel anti-liver fibrosis formula with luteolin, licochalcone A, aloe-emodin and acacetin by network pharmacology and transcriptomics analysis. Pharmaceutical biology. 2021 Dec; 59(1):1594-1606. doi: 10.1080/13880209.2021.1999275. [PMID: 34808067]
Yitong Liu, Mapa S T Mapa, Robert L Sprando. Anthraquinones inhibit cytochromes P450 enzyme activity in silico and in vitro. Journal of applied toxicology : JAT. 2021 09; 41(9):1438-1445. doi: 10.1002/jat.4134. [PMID: 33438235]
Corrado L Galli, Serena Cinelli, Paola Ciliutti, Gloria Melzi, Marina Marinovich. Aloe-emodin, a hydroxyanthracene derivative, is not genotoxic in an in vivo comet test. Regulatory toxicology and pharmacology : RTP. 2021 Aug; 124(?):104967. doi: 10.1016/j.yrtph.2021.104967. [PMID: 34062205]
Hans Wilhelm Rauwald, Ralf Maucher, Gerd Dannhardt, Kenny Kuchta. Dihydroisocoumarins, Naphthalenes, and Further Polyketides from Aloe vera and A. plicatilis: Isolation, Identification and Their 5-LOX/COX-1 Inhibiting Potency. Molecules (Basel, Switzerland). 2021 Jul; 26(14):. doi: 10.3390/molecules26144223. [PMID: 34299499]
Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
Ibrahim Halil Gecibesler, Faruk Disli, Sinan Bayindir, Mahmut Toprak, Ali Riza Tufekci, Ayse Sahin Yaglıoglu, Muhammed Altun, Alpaslan Kocak, Ibrahim Demirtas, Sevki Adem. The isolation of secondary metabolites from Rheum ribes L. and the synthesis of new semi-synthetic anthraquinones: Isolation, synthesis and biological activity. Food chemistry. 2021 Apr; 342(?):128378. doi: 10.1016/j.foodchem.2020.128378. [PMID: 33508903]
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