Safrol (BioDeep_00000859456)

   


代谢物信息卡片


InChI=1\C10H10O2\c1-2-3-8-4-5-9-10(6-8)12-7-11-9\h2,4-6H,1,3,7H

化学式: C10H10O2 (162.06807600000002)
中文名称: 黄樟素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=CCC1=CC2=C(C=C1)OCO2
InChI: InChI=1S/C10H10O2/c1-2-3-8-4-5-9-10(6-8)12-7-11-9/h2,4-6H,1,3,7H2

描述信息

同义名列表

74 个代谢物同义名

InChI=1\C10H10O2\c1-2-3-8-4-5-9-10(6-8)12-7-11-9\h2,4-6H,1,3,7H; BENZENE,1-ALLYL,3,4-METHYLENEDIOXY SAFROLE; 5-19-01-00553 (Beilstein Handbook Reference); 4-Allylpyrocatechol formaldehyde acetal; Benzene, 4-allyl-1,2-(methylenedioxy)-; [1,2-(Methylenedioxy)-4-allyl]benzene; Benzene, 1,2-methylenedioxy-4-allyl-; 1,2-(Methylenedioxy)-4-allylbenzene; m-Allylpyrocatechin methylene ether; (Allyldioxy)benzene methylene ether; 1-Allyl-3,4-(methylenedioxy)benzene; 4-Allyl-1,2-(methylenedioxy)benzene; EPA Pesticide Chemical Code 097901; 1-Allyl-3,4-methylenedioxybenzene; 4-Allyl-1,2-methylenedioxybenzene; 1,3-Benzodioxole, 5-(2-propenyl)-; Allylpyrocatechol methylene ether; 1,2-Methylenedioxy-4-allylbenzene; Allyldioxybenzene methylene ether; 3,4-(Methylenedioxy)allylbenzene; 5-(2-Propenyl)-1,3-benzodioxole; 5-Prop-2-enyl-1,3-benzodioxole; Allylcatechol methylene ether; 1,3-Benzodioxole, 5-allyl-; 5-Allyl-1,3-benzodioxole; WLN: T56 BO DO CHJ G2U1; RCRA waste number U203; SDCCGMLS-0066708.P001; RCRA waste no. U203; 4-Allylpyrocatechol; EINECS 202-345-4; Spectrum2_000775; Spectrum5_000843; Spectrum4_001939; Spectrum3_001105; NCGC00091122-02; Spectrum_001446; Caswell No. 729; NCGC00091122-03; SPECTRUM1503620; NCGC00091122-01; DivK1c_001022; BSPBio_002810; KBioSS_001926; KBioGR_002319; NINDS_001022; KBio2_007062; ZINC00002050; KBio3_002030; KBio2_001926; KBio1_001022; KBio2_004494; SPBio_000850; IDI1_001022; S9652_SIGMA; BRN 0136380; Safrole MF; Rhyuno oil; HSDB 2653; CCRIS 553; Shikimole; 1406-55-9; NSC 11831; AI3-00514; 8022-92-2; sassafras; ST5406117; Shikomol; NSC11831; Safrene; safrole; 94-59-7; Safrol; C10490



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

135 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Xin Wang, Guangyun Ran, Yufen Liao, Bowen Gong, Chutian Wu, Rong Tan, Ying Liu, Shiyu Zhang, Ying Peng, Weiwei Li, Jiang Zheng. Formation of RNA adducts resulting from metabolic activation of spice ingredient safrole mediated by P450 enzymes and sulfotransferases. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Feb; ?(?):113688. doi: 10.1016/j.fct.2023.113688. [PMID: 36841326]
  • Yesenia Pacheco-Hernández, Nemesio Villa-Ruano, Ramiro Cruz-Duran, Elvia Becerra-Martínez, Edmundo Lozoya-Gloria. 1 H-NMR Metabolomics Profiling and Volatile Content of 'Hoja Santa' (Piper auritum Kunth): A Millenary Edible Plant Consumed in Mexico. Chemistry & biodiversity. 2022 Dec; 19(12):e202200667. doi: 10.1002/cbdv.202200667. [PMID: 36417317]
  • Katharina Friedrich, Nicole S Wermter, Lars Andernach, Katja Witzel, Franziska S Hanschen. Formation of volatile sulfur compounds and S-methyl-l-cysteine sulfoxide in Brassica oleracea vegetables. Food chemistry. 2022 Jul; 383(?):132544. doi: 10.1016/j.foodchem.2022.132544. [PMID: 35247727]
  • Nina Reis Soares, Caio Túlio Rodrigues Correa, Jhonata Costa da Silva, Jacson Rondinelli da Silva Negreiros, Vânia Helena Techio, Giovana Augusta Torres. Comparative cytogenetics of three economically important Piper L. species from the Brazilian Amazon. Protoplasma. 2022 Jul; 259(4):1099-1108. doi: 10.1007/s00709-021-01721-2. [PMID: 34762169]
  • Ying Nie, Yuan Luo, Shajie Luo, Xiujun Cao, Guoxin Song, Chunhui Deng. Amphiphilic copolymers grafted on monodisperse magnetic microspheres as an efficient adsorbent for the extraction of safrole in the plasma. Journal of chromatography. A. 2022 Jan; 1662(?):462733. doi: 10.1016/j.chroma.2021.462733. [PMID: 34902718]
  • Mohamed Joonus Aynul Fazmiya, Arshiya Sultana, Khaleequr Rahman, Md Belal Bin Heyat, Sumbul, Faijan Akhtar, Salabat Khan, Seth Christopher Yaw Appiah. Current Insights on Bioactive Molecules, Antioxidant, Anti-Inflammatory, and Other Pharmacological Activities of Cinnamomum camphora Linn. Oxidative medicine and cellular longevity. 2022; 2022(?):9354555. doi: 10.1155/2022/9354555. [PMID: 36246399]
  • Maria Suely Siqueira Ferraz, Lêda Rita D'Antonino Faroni, Fernanda Fernandes Heleno, Adalberto Hipólito de Sousa, Lucas Henrique Figueiredo Prates, Alessandra Aparecida Zinato Rodrigues. Method Validation and Evaluation of Safrole Persistence in Cowpea Beans Using Headspace Solid-Phase Microextraction and Gas Chromatography. Molecules (Basel, Switzerland). 2021 Nov; 26(22):. doi: 10.3390/molecules26226914. [PMID: 34834007]
  • Sascha K Manier, Lea Wagmann, Armin A Weber, Markus R Meyer. Abuse of nutmeg seeds: Detectable by means of liquid chromatography-mass spectrometry techniques?. Drug testing and analysis. 2021 Jul; 13(7):1440-1444. doi: 10.1002/dta.3027. [PMID: 33720530]
  • Yuqi Fan, Dongyue Yang, Xuhua Huang, Guangzhe Yao, Wei Wang, Mengyuan Gao, Xiaohua Jia, Huizi Ouyang, Yanxu Chang, Jun He. Pharmacokinetic Study of Safrole and Methyl Eugenol after Oral Administration of the Essential Oil Extracts of Asarum in Rats by GC-MS. BioMed research international. 2021; 2021(?):6699033. doi: 10.1155/2021/6699033. [PMID: 33829063]
  • Xiangqian Ye, Xiaoling Zou, Fafu Tian, Honglin He. Feasibility study on recycled vegetable oil waste and recycled polyethylene for the modification of aged asphalt. PloS one. 2021; 16(1):e0244159. doi: 10.1371/journal.pone.0244159. [PMID: 33400695]
  • Nigel J Gooderham, Samuel M Cohen, Gerhard Eisenbrand, Shoji Fukushima, F Peter Guengerich, Stephen S Hecht, Ivonne M C M Rietjens, Thomas J Rosol, Jeanne M Davidsen, Christie L Harman, Ian J Murray, Sean V Taylor. FEMA GRAS assessment of natural flavor complexes: Clove, cinnamon leaf and West Indian bay leaf-derived flavoring ingredients. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2020 Nov; 145(?):111585. doi: 10.1016/j.fct.2020.111585. [PMID: 32702506]
  • Chia-Jung Lee, Chun-Wei Huang, Lih-Geeng Chen, Ching-Chiung Wang. (+)-Erythro-Δ8'-7S,8R-Dihydroxy-3,3',5'-Trimethoxy-8-O-4'-Neolignan, an Anti-Acne Component in Degreasing Myristica fragrans Houtt. Molecules (Basel, Switzerland). 2020 Oct; 25(19):. doi: 10.3390/molecules25194563. [PMID: 33036279]
  • Merja A Neukamm, Hannes M Schwelm, Simon Vieser, Nadine Schiesel, Volker Auwärter. Detection of Nutmeg Abuse by Gas Chromatography-Mass Spectrometric Screening of Urine. Journal of analytical toxicology. 2020 Jan; 44(1):103-108. doi: 10.1093/jat/bkz054. [PMID: 31504590]
  • Linlin Hu, Fei Wu, Jie He, Lingjun Zhong, Yifan Song, Hua Shao. Cytotoxicity of safrole in HepaRG cells: studies on the role of CYP1A2-mediated ortho-quinone metabolic activation. Xenobiotica; the fate of foreign compounds in biological systems. 2019 Dec; 49(12):1504-1515. doi: 10.1080/00498254.2019.1590882. [PMID: 30865484]
  • Li-Jun Yue, Xi-Yu Zhu, Rui-Sha Li, Hui-Jing Chang, Bing Gong, Chong-Chong Tian, Chang Liu, Yun-Xing Xue, Qing Zhou, Tian-Shu Xu, Dong-Jin Wang. S‑allyl‑cysteine sulfoxide (alliin) alleviates myocardial infarction by modulating cardiomyocyte necroptosis and autophagy. International journal of molecular medicine. 2019 Nov; 44(5):1943-1951. doi: 10.3892/ijmm.2019.4351. [PMID: 31573046]
  • Han-Hsing Tsou, Hsiao-Tung Ko, Chia-Tzu Chen, Tse-Wen Wang, Chien-Hung Lee, Tsung-Yun Liu, Hsiang-Tsui Wang. Betel quid containing safrole enhances metabolic activation of tobacco specific 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Environmental pollution (Barking, Essex : 1987). 2019 Aug; 251(?):13-21. doi: 10.1016/j.envpol.2019.04.080. [PMID: 31071628]
  • Laura Marabini, Corrado L Galli, Pierpaolo La Fauci, Marina Marinovich. Effect of plant extracts on the genotoxicity of 1'-hydroxy alkenylbenzenes. Regulatory toxicology and pharmacology : RTP. 2019 Jul; 105(?):36-41. doi: 10.1016/j.yrtph.2019.03.017. [PMID: 30935955]
  • Alexander V Samet, Oksana G Shevchenko, Vyacheslav V Rusak, Eduard M Chartov, Andrey B Myshlyavtsev, Daniil A Rusanov, Marina N Semenova, Victor V Semenov. Antioxidant Activity of Natural Allylpolyalkoxybenzene Plant Essential Oil Constituents. Journal of natural products. 2019 Jun; ?(?):. doi: 10.1021/acs.jnatprod.8b00878. [PMID: 31244145]
  • Kamlesh S Yadav, Pratibha Yadav, Satyawati Sharma, Sunil K Khare. Role of Musa paradisiaca ascorbate peroxidase in the transformation of methyl phenyl sulfide to its sulfoxide. International journal of biological macromolecules. 2019 Feb; 122(?):962-968. doi: 10.1016/j.ijbiomac.2018.11.014. [PMID: 30408454]
  • Toshihide Takeshita, Fumiya Tao, Nobuhiko Kojima, Robert A Kanaly. Triple quadrupole mass spectrometry comparative DNA adductomics of Hep G2 cells following exposure to safrole. Toxicology letters. 2019 Jan; 300(?):92-104. doi: 10.1016/j.toxlet.2018.10.023. [PMID: 30394309]
  • Ai-Hong Yang, Lei Zhang, De-Xian Zhi, Wen-Li Liu, Xue Gao, Xin He. Identification and analysis of the reactive metabolites related to the hepatotoxicity of safrole. Xenobiotica; the fate of foreign compounds in biological systems. 2018 Nov; 48(11):1164-1172. doi: 10.1080/00498254.2017.1399227. [PMID: 29082813]
  • A L Wollenberg, T M O'Shea, J H Kim, A Czechanski, L G Reinholdt, M V Sofroniew, T J Deming. Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. Biomaterials. 2018 09; 178(?):527-545. doi: 10.1016/j.biomaterials.2018.03.057. [PMID: 29657091]
  • Chun-Shun Li, Ariel M Sarotti, Peng Huang, Uyen T Dang, Julian G Hurdle, Tamara P Kondratyuk, John M Pezzuto, James Turkson, Shugeng Cao. NF-κB inhibitors, unique γ-pyranol-γ-lactams with sulfide and sulfoxide moieties from Hawaiian plant Lycopodiella cernua derived fungus Paraphaeosphaeria neglecta FT462. Scientific reports. 2017 09; 7(1):10424. doi: 10.1038/s41598-017-10537-1. [PMID: 28874704]
  • Katsunori Anezaki, Ayaka Matsuda, Takashi Matsuishi. Concentration and congener pattern of polychlorinated biphenyls in blubber and liver of Hubbs' beaked whale (Mesoplodon carlhubbsi), using a sulfoxide and an Ag-ION solid phase extraction cartridge as a simplified cleanup technique for biological samples. Marine pollution bulletin. 2016 Dec; 113(1-2):282-286. doi: 10.1016/j.marpolbul.2016.09.051. [PMID: 27707471]
  • Morina Adfa, Rizki Rahmad, Masayuki Ninomiya, Salprima Yudha S, Kaori Tanaka, Mamoru Koketsu. Antileukemic activity of lignans and phenylpropanoids of Cinnamomum parthenoxylon. Bioorganic & medicinal chemistry letters. 2016 Feb; 26(3):761-764. doi: 10.1016/j.bmcl.2015.12.096. [PMID: 26774581]
  • Jee Hwan Yi, Haribalan Perumalsamy, Karuppasamy Sankarapandian, Byeoung-Ryeol Choi, Young-Joon Ahn. Fumigant Toxicity of Phenylpropanoids Identified in Asarum sieboldii Aerial Parts to Lycoriella ingenua (Diptera: Sciaridae) and Coboldia fuscipes (Diptera: Scatopsidae). Journal of economic entomology. 2015 Jun; 108(3):1208-14. doi: 10.1093/jee/tov064. [PMID: 26470247]
  • Wei Ding, Dan D Levy, Michelle E Bishop, Mason G Pearce, Kelly J Davis, Alan M Jeffrey, Jian-Dong Duan, Gary M Williams, Gene A White, Lascelles E Lyn-Cook, Mugimane G Manjanatha. In vivo genotoxicity of estragole in male F344 rats. Environmental and molecular mutagenesis. 2015 May; 56(4):356-65. doi: 10.1002/em.21918. [PMID: 25361439]
  • Xin Chao Liu, Zhi Long Liu. Analysis of the essential oil of Illicium henryi Diels root bark and its insecticidal activity against Liposcelis bostrychophila Badonnel. Journal of food protection. 2015 Apr; 78(4):772-7. doi: 10.4315/0362-028x.jfp-14-407. [PMID: 25836404]
  • Ann M Bode, Zigang Dong. Toxic phytochemicals and their potential risks for human cancer. Cancer prevention research (Philadelphia, Pa.). 2015 Jan; 8(1):1-8. doi: 10.1158/1940-6207.capr-14-0160. [PMID: 25348854]
  • Nicholas John Sadgrove, Graham Lloyd Jones. Cytogeography of essential oil chemotypes of Eremophila longifolia F. Muell (Scrophulariaceae). Phytochemistry. 2014 Sep; 105(?):43-51. doi: 10.1016/j.phytochem.2014.05.005. [PMID: 24874947]
  • Ewelina Krol, Gabriela Pastuch-Gawolek, Dawid Nidzworski, Michal Rychlowski, Wieslaw Szeja, Grzegorz Grynkiewicz, Boguslaw Szewczyk. Synthesis and antiviral activity of a novel glycosyl sulfoxide against classical swine fever virus. Bioorganic & medicinal chemistry. 2014 May; 22(9):2662-70. doi: 10.1016/j.bmc.2014.03.027. [PMID: 24721828]
  • Xu Song, Zhongqiong Yin, Kuichuan Ye, Qin Wei, Renrong Jia, Lijun Zhou, Yonghua Du, Jiao Xu, Xiaoxia Liang, Changliang He, Gang Shu, Lizi Yin, Cheng Lv. Anti-hepatoma effect of safrole from Cinnamomum longepaniculatum leaf essential oil in vitro. International journal of clinical and experimental pathology. 2014; 7(5):2265-72. doi: . [PMID: 24966935]
  • Megumi Iwasa, Toshiki Iwasaki, Toshirou Ono, Mitsuo Miyazawa. Chemical composition and major odor-active compounds of essential oil from PINELLIA TUBER (dried rhizome of Pinellia ternata) as crude drug. Journal of oleo science. 2014; 63(2):127-35. doi: 10.5650/jos.ess13092. [PMID: 24500103]
  • Maria Lucia Leporatti, Giorgio Pintore, Marzia Foddai, Mario Chessa, Andrea Piana, Giacomo Luigi Petretto, Maria Dolores Masia, Giuseppe Mangano, Marcello Nicoletti. Chemical, biological, morphoanatomical and antimicrobial study of Ocotea puchury-major Mart. Natural product research. 2014; 28(5):294-300. doi: 10.1080/14786419.2013.858338. [PMID: 24274027]
  • M Schäffer, T Gröger, M Pütz, R Zimmermann. Forensic profiling of sassafras oils based on comprehensive two-dimensional gas chromatography. Forensic science international. 2013 Jun; 229(1-3):108-15. doi: 10.1016/j.forsciint.2013.03.046. [PMID: 23683915]
  • Le Su, Haiyan Zhang, Jing Zhao, Shangli Zhang, Yun Zhang, Baoxiang Zhao, Junying Miao. Safrole-2',3'-oxide induces atherosclerotic plaque vulnerability in apolipoprotein E-knockout mice. Toxicology letters. 2013 Feb; 217(2):129-36. doi: 10.1016/j.toxlet.2012.12.011. [PMID: 23270965]
  • Ramon Lavado, Rosaura Aparicio-Fabre, Daniel Schlenk. Effects of salinity acclimation on the pesticide-metabolizing enzyme flavin-containing monooxygenase (FMO) in rainbow trout (Oncorhynchus mykiss). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2013 Jan; 157(1):9-15. doi: 10.1016/j.cbpc.2012.08.004. [PMID: 22981832]
  • Mario Thevis, Ines Möller, Simon Beuck, Wilhelm Schänzer. Synthesis, mass spectrometric characterization, and analysis of the PPARδ agonist GW1516 and its major human metabolites: targets in sports drug testing. Methods in molecular biology (Clifton, N.J.). 2013; 952(?):301-12. doi: 10.1007/978-1-62703-155-4_22. [PMID: 23100242]
  • Li-Ching Shen, Su-Yin Chiang, Ming-Huan Lin, Wen-Sheng Chung, Kuen-Yuh Wu. In vivo formation of N7-guanine DNA adduct by safrole 2',3'-oxide in mice. Toxicology letters. 2012 Sep; 213(3):309-15. doi: 10.1016/j.toxlet.2012.07.006. [PMID: 22820429]
  • Erryana Martati, Marelle G Boersma, Albertus Spenkelink, Dambar B Khadka, Peter J van Bladeren, Ivonne M C M Rietjens, Ans Punt. Physiologically based biokinetic (PBBK) modeling of safrole bioactivation and detoxification in humans as compared with rats. Toxicological sciences : an official journal of the Society of Toxicology. 2012 Aug; 128(2):301-16. doi: 10.1093/toxsci/kfs174. [PMID: 22588462]
  • Danielle S Fisher, Simon A Handley, Robert J Flanagan, David M Taylor. Plasma concentrations of quetiapine, N-desalkylquetiapine, o-desalkylquetiapine, 7-hydroxyquetiapine, and quetiapine sulfoxide in relation to quetiapine dose, formulation, and other factors. Therapeutic drug monitoring. 2012 Aug; 34(4):415-21. doi: 10.1097/ftd.0b013e3182603f62. [PMID: 22777152]
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  • Alessandra Piras, Antonella Rosa, Bruno Marongiu, Angela Atzeri, M Assunta Dessì, Danilo Falconieri, Silvia Porcedda. Extraction and separation of volatile and fixed oils from seeds of Myristica fragrans by supercritical CO₂: chemical composition and cytotoxic activity on Caco-2 cancer cells. Journal of food science. 2012 Apr; 77(4):C448-53. doi: 10.1111/j.1750-3841.2012.02618.x. [PMID: 22429024]
  • Ana Paula C Rodrigues, Luciana M M Costa, Bruna L R Santos, Rodolfo C Maia, Ana L P Miranda, Eliezer J Barreiro, Carlos A M Fraga. Novel furfurylidene N-acylhydrazones derived from natural safrole: discovery of LASSBio-1215, a new potent antiplatelet prototype. Journal of enzyme inhibition and medicinal chemistry. 2012 Feb; 27(1):101-9. doi: 10.3109/14756366.2011.578575. [PMID: 21612374]
  • Su-ying Hu, Gang He, Bei Chen, Lang-jun Cui, Jian-xiong Yang. [Genetic diversity and volatile components of Asarum sieboldii in Qin-ba region]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2012 Feb; 35(2):188-94. doi: ". [PMID: 22822661]
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  • Roberto Parise-Filho, Michelli Pastrello, Carla Emygdio Pereira Camerlingo, Gisele Juni Silva, Leonardo Aguiar Agostinho, Thaís de Souza, Fátima Maria Motter Magri, Roberto Rodrigues Ribeiro, Carlos Alberto Brandt, Michelle Carneiro Polli. The anti-inflammatory activity of dillapiole and some semisynthetic analogues. Pharmaceutical biology. 2011 Nov; 49(11):1173-9. doi: 10.3109/13880209.2011.575793. [PMID: 22014265]
  • Abhijeet Y Deshpande, Sandip Gurav, Ravindra Punde, Vishal Zambre, Rahul Kulkarni, Sarvesh Pandey, Ashish Mungantiwar, Ramesh Mullangi. Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of ethionamide and ethionamide sulfoxide in human plasma: application to a human pharmacokinetic study. Biomedical chromatography : BMC. 2011 Sep; 25(9):985-94. doi: 10.1002/bmc.1554. [PMID: 21268048]
  • Stephan G Walch, Thomas Kuballa, Wolf Stühlinger, Dirk W Lachenmeier. Determination of the biologically active flavour substances thujone and camphor in foods and medicines containing sage (Salvia officinalis L.). Chemistry Central journal. 2011 Jul; 5(?):44. doi: 10.1186/1752-153x-5-44. [PMID: 21777420]
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  • E Martati, M G Boersma, A Spenkelink, D B Khadka, A Punt, J Vervoort, P J van Bladeren, I M C M Rietjens. Physiologically based biokinetic (PBBK) model for safrole bioactivation and detoxification in rats. Chemical research in toxicology. 2011 Jun; 24(6):818-34. doi: 10.1021/tx200032m. [PMID: 21446753]
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