1-beta-D-Arabinofuranosylthymine (BioDeep_00000842242)

   


代谢物信息卡片


1-beta-D-Arabinofuranosylthymine

化学式: C10H14N2O6 (258.0852)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
InChI: InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)

描述信息

D000890 - Anti-Infective Agents > D000998 - Antiviral Agents

同义名列表

1 个代谢物同义名

1-beta-D-Arabinofuranosylthymine



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ADA, DCK, GJA1, GLI3, PNP, POLB, RAD51, TK2, TYMS
Peripheral membrane protein 1 ADA
Endoplasmic reticulum membrane 2 GJA1, TYRO3
Nucleus 8 DCK, GJA1, GLI3, POLB, RAD51, TK1, TYMS, TYRO3
cytosol 8 ADA, DCK, GJA1, GLI3, PNP, RAD51, TK1, TYMS
centrosome 1 RAD51
nucleoplasm 5 DCK, GJA1, GLI3, POLB, RAD51
Cell membrane 4 ADA, GJA1, GJB2, TYRO3
Multi-pass membrane protein 2 GJA1, GJB2
cell junction 2 ADA, GJA1
cell surface 2 ADA, TYRO3
Golgi apparatus 1 GJA1
Golgi membrane 1 GJA1
mitochondrial inner membrane 1 TYMS
Lysosome 1 ADA
plasma membrane 5 ADA, GJA1, GJB2, IFNLR1, TYRO3
Membrane 3 ADA, IFNLR1, TYRO3
apical plasma membrane 1 GJA1
extracellular exosome 1 PNP
endoplasmic reticulum 1 GJA1
extracellular space 1 PNP
perinuclear region of cytoplasm 2 GJB2, RAD51
gap junction 2 GJA1, GJB2
intercalated disc 1 GJA1
mitochondrion 5 DCK, GJA1, RAD51, TK2, TYMS
protein-containing complex 2 POLB, RAD51
intracellular membrane-bounded organelle 2 GJA1, GLI3
Single-pass type I membrane protein 2 IFNLR1, TYRO3
Secreted 1 PNP
extracellular region 1 PNP
Mitochondrion matrix 2 RAD51, TYMS
mitochondrial matrix 3 RAD51, TK2, TYMS
Extracellular side 1 ADA
Cytoplasmic vesicle lumen 1 ADA
anchoring junction 1 ADA
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 RAD51
external side of plasma membrane 1 ADA
nucleolus 2 GLI3, RAD51
Mitochondrion inner membrane 1 TYMS
Membrane raft 1 GJA1
focal adhesion 1 GJA1
microtubule 1 POLB
PML body 1 RAD51
Cell junction, gap junction 2 GJA1, GJB2
connexin complex 2 GJA1, GJB2
contractile muscle fiber 1 GJA1
fascia adherens 1 GJA1
intermediate filament 1 GJA1
lateral plasma membrane 2 GJA1, GJB2
axoneme 1 GLI3
ciliary tip 1 GLI3
nuclear speck 1 GLI3
receptor complex 1 TYRO3
ciliary base 1 GLI3
cilium 1 GLI3
chromatin 1 RAD51
Chromosome 1 RAD51
chromosome, telomeric region 1 RAD51
nuclear chromosome 1 RAD51
site of double-strand break 1 RAD51
nuclear envelope 1 TYRO3
lateral element 1 RAD51
Golgi-associated vesicle membrane 1 GJA1
cell body 1 GJB2
ficolin-1-rich granule lumen 1 PNP
secretory granule lumen 1 PNP
transcription repressor complex 1 GLI3
male germ cell nucleus 1 RAD51
tight junction 1 GJA1
condensed nuclear chromosome 1 RAD51
endoplasmic reticulum-Golgi intermediate compartment 1 GJB2
spindle microtubule 1 POLB
condensed chromosome 1 RAD51
cell-cell contact zone 1 GJA1
astrocyte projection 1 GJB2
presynaptic intermediate filament cytoskeleton 1 RAD51
GLI-SUFU complex 1 GLI3
nuclear ubiquitin ligase complex 1 RAD51
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Xinyu Zheng, Mathias Lundberg, Anna Karlsson, Magnus Johansson. Lipid-mediated protein delivery of suicide nucleoside kinases. Cancer research. 2003 Oct; 63(20):6909-13. doi: . [PMID: 14583490]
  • G A Gentry, N Lawrence, W Lushbaugh. Isolation and differentiation of herpes simplex virus and Trichomonas vaginalis in cell culture. Journal of clinical microbiology. 1985 Aug; 22(2):199-204. doi: 10.1128/jcm.22.2.199-204.1985. [PMID: 2993349]
  • H Machida, S Sakata, M Morozumi, T Kiyanagi, A Kuninaka, H Yoshino. Comparison of the in vitro and in vivo anti-herpes activities of 1-beta-D-arabinofuranosylthymine and its 5'-monophosphate. Antiviral research. 1982 Sep; 2(4):217-26. doi: 10.1016/0166-3542(82)90044-4. [PMID: 6293376]
  • D Falke, H Moser, D Link, W E Müller. The effects of alpha- and beta-D-arabinosyladenosine and beta-D-arabinosylthymine on the synthesis of HSV types 1- and 2-infected cells. Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie. 1979; 38(?):197-203. doi: NULL. [PMID: 230716]