Nickel Chloride (BioDeep_00000840336)
代谢物信息卡片
Nickel Chloride
化学式: Cl2Ni (127.873053)
中文名称: 氯化镍分析滴定液
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: Cl[Ni]Cl
InChI: /q
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Saade Abdalkareem Jasim, Sahar Golgouneh, Mustafa Musa Jaber, Sayit I Indiaminov, Fahad Alsaikhan, Ali Thaeer Hammid, Yasser Fakri Mustafa, Yasir Salam Karim, Mohammed Q Sultan, Maryam Norbakhsh. Effects of short-term exposure to the heavy metal, nickel chloride (Nicl2) on gill histology and osmoregulation components of the gray mullet, Mugil cephalus.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2022 Aug; 258(?):109361. doi:
10.1016/j.cbpc.2022.109361. [PMID: 35525465] - Imane Salah, Ounassa Adjroud, Awatef Elwej. Protective Effects of Selenium and Zinc Against Nickel Chloride-Induced Hormonal Changes and Oxidative Damage in Thyroid of Pregnant Rats.
Biological trace element research.
2022 May; 200(5):2183-2194. doi:
10.1007/s12011-021-02815-x. [PMID: 34247319] - Koichi Sato, Chihiro Mogi, Alan J Mighell, Fumikazu Okajima. A missense mutation of Leu74Pro of OGR1 found in familial amelogenesis imperfecta actually causes the loss of the pH-sensing mechanism.
Biochemical and biophysical research communications.
2020 06; 526(4):920-926. doi:
10.1016/j.bbrc.2020.04.005. [PMID: 32279993] - Omamuyovwi M Ijomone, Mahfuzur R Miah, Grace T Akingbade, Hana Bucinca, Michael Aschner. Nickel-Induced Developmental Neurotoxicity in C. elegans Includes Cholinergic, Dopaminergic and GABAergic Degeneration, Altered Behaviour, and Increased SKN-1 Activity.
Neurotoxicity research.
2020 Apr; 37(4):1018-1028. doi:
10.1007/s12640-020-00175-3. [PMID: 32034695] - Solomon E Owumi, Yusuff O Olayiwola, Gbenga E Alao, Michael A Gbadegesin, Oyeronke A Odunola. Cadmium and nickel co-exposure exacerbates genotoxicity and not oxido-inflammatory stress in liver and kidney of rats: Protective role of omega-3 fatty acid.
Environmental toxicology.
2020 Feb; 35(2):231-241. doi:
10.1002/tox.22860. [PMID: 31639282] - Sylwia Terpilowska, Andrzej Krzysztof Siwicki. Pro- and antioxidant activity of chromium(III), iron(III), molybdenum(III) or nickel(II) and their mixtures.
Chemico-biological interactions.
2019 Jan; 298(?):43-51. doi:
10.1016/j.cbi.2018.10.028. [PMID: 30389395] - Shohei Yokota, Kazuichi Nakamura, Ryo Kamata. A comparative study of nickel nanoparticle and ionic nickel toxicities in zebrafish: histopathological changes and oxidative stress.
The Journal of toxicological sciences.
2019; 44(11):737-751. doi:
10.2131/jts.44.737. [PMID: 31708531] - Tzu-Chin Wu, Shu-Ting Chan, Chih-Ning Chang, Pei-Syuan Yu, Cheng-Hung Chuang, Shu-Lan Yeh. Quercetin and chrysin inhibit nickel-induced invasion and migration by downregulation of TLR4/NF-κB signaling in A549 cells.
Chemico-biological interactions.
2018 Aug; 292(?):101-109. doi:
10.1016/j.cbi.2018.07.010. [PMID: 30016632] - Mohammad Hadi Zarei, Seyed Farshad Hosseini Shirazi, Marjan Aghvami, Ahmad Salimi, Jalal Pourahmad. Analysis of cytotoxic effects of nickel on human blood lymphocytes.
Toxicology mechanisms and methods.
2018 Feb; 28(2):79-86. doi:
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Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
2017 Aug; 47(8):1069-1078. doi:
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Chemosphere.
2017 Jan; 166(?):445-452. doi:
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Bulletin of experimental biology and medicine.
2016 Dec; 162(2):199-202. doi:
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Oncotarget.
2016 Nov; 7(48):79747-79760. doi:
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BMC structural biology.
2016 10; 16(1):18. doi:
10.1186/s12900-016-0068-2. [PMID: 27788689] - Imed-Eddine Kadi, Faouzi Dahdouh. Vitamin C pretreatment protects from nickel-induced acute nephrotoxicity in mice.
Arhiv za higijenu rada i toksikologiju.
2016 Sep; 67(3):210-215. doi:
10.1515/aiht-2016-67-2753. [PMID: 27749260] - Spyros Perontsis, Antonios G Hatzidimitriou, Athanasios N Papadopoulos, George Psomas. Nickel-diflunisal complexes: synthesis, characterization, in vitro antioxidant activity and interaction with DNA and albumins.
Journal of inorganic biochemistry.
2016 09; 162(?):9-21. doi:
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Bulletin of experimental biology and medicine.
2016 Aug; 161(4):495-500. doi:
10.1007/s10517-016-3446-7. [PMID: 27597056] - Xiaoqiang Guo, Yanmin Zhang, Qiang Zhang, Pingping Fa, Yaoting Gui, Guoquan Gao, Zhiming Cai. The regulatory role of nickel on H3K27 demethylase JMJD3 in kidney cancer cells.
Toxicology and industrial health.
2016 Jul; 32(7):1286-92. doi:
10.1177/0748233714552687. [PMID: 25427687] - Shuang Yin, Hongrui Guo, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Kun Tang, Jian Li. Nickel Chloride (NiCl2) Induces Histopathological Lesions via Oxidative Damage in the Broiler's Bursa of Fabricius.
Biological trace element research.
2016 May; 171(1):214-23. doi:
10.1007/s12011-015-0528-8. [PMID: 26440478] - Hongrui Guo, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Bangyuan Wu, Kejie Chen, Jie Deng. Nickel chloride (NiCl2) induces endoplasmic reticulum (ER) stress by activating UPR pathways in the kidney of broiler chickens.
Oncotarget.
2016 Apr; 7(14):17508-19. doi:
10.18632/oncotarget.7919. [PMID: 26956054] - Hongrui Guo, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Bangyuan Wu, Kejie Chen, Jie Deng. Dietary NiCl₂ causes G₂/M cell cycle arrest in the broiler's kidney.
Oncotarget.
2015 Nov; 6(34):35964-77. doi:
10.18632/oncotarget.5934. [PMID: 26440151] - Hongrui Guo, Huidan Deng, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Bangyuan Wu, Kejie Chen. Nickel chloride (NiCl2)-caused inflammatory responses via activation of NF-κB pathway and reduction of anti-inflammatory mediator expression in the kidney.
Oncotarget.
2015 Oct; 6(30):28607-20. doi:
10.18632/oncotarget.5759. [PMID: 26417933] - Hongrui Guo, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Bangyuan Wu, Kejie Chen, Jie Deng. Modulation of the PI3K/Akt Pathway and Bcl-2 Family Proteins Involved in Chicken's Tubular Apoptosis Induced by Nickel Chloride (NiCl₂).
International journal of molecular sciences.
2015 Sep; 16(9):22989-3011. doi:
10.3390/ijms160922989. [PMID: 26404262] - Yunlei Han, Rui Wang, Zhirong Yang, Yuhua Zhan, Yao Ma, Shuzhen Ping, Liwen Zhang, Min Lin, Yongliang Yan. 1-Aminocyclopropane-1-Carboxylate Deaminase from Pseudomonas stutzeri A1501 Facilitates the Growth of Rice in the Presence of Salt or Heavy Metals.
Journal of microbiology and biotechnology.
2015 Jul; 25(7):1119-28. doi:
10.4014/jmb.1412.12053. [PMID: 25674802] - Ahmet Topal, Muhammed Atamanalp, Ertan Oruç, Mesut Bünyami Halıcı, Melda Şişecioğlu, Hüseyin Serkan Erol, Arzu Gergit, Bahar Yılmaz. Neurotoxic effects of nickel chloride in the rainbow trout brain: Assessment of c-Fos activity, antioxidant responses, acetylcholinesterase activity, and histopathological changes.
Fish physiology and biochemistry.
2015 Jun; 41(3):625-34. doi:
10.1007/s10695-015-0033-1. [PMID: 25666867] - V V Ivanishchev, E A Abramova. Accumulation of nickel ions in seedlings of Vicia sativa L. and manifestations of oxidative stress.
Environmental science and pollution research international.
2015 May; 22(10):7897-905. doi:
10.1007/s11356-015-4173-8. [PMID: 25655753] - Salha Boulila, Abdelfattah Elfeki, Hassane Oudadesse, Hafed Elfeki. Substitution effects of a carbonated hydroxyapatite biomaterial against intoxication chloride nickel-exposed rats.
Toxicology mechanisms and methods.
2015 Mar; 25(3):155-65. doi:
10.3109/15376516.2014.1003358. [PMID: 25560666] - Jason Brocato, Michelle Hernandez, Freda Laulicht, Hong Sun, Magdy Shamy, Mansour A Alghamdi, Mamdouh I Khoder, Thomas Kluz, Lung-Chi Chen, Max Costa. In Vivo Exposures to Particulate Matter Collected from Saudi Arabia or Nickel Chloride Display Similar Dysregulation of Metabolic Syndrome Genes.
Journal of toxicology and environmental health. Part A.
2015; 78(23-24):1421-36. doi:
10.1080/15287394.2015.1095689. [PMID: 26692068] - Mohd Kafeel Ahmad Ansari, Altaf Ahmad, Shahid Umar, Munir Hussain Zia, Muhammad Iqbal, Gary Owens. Genotypic variation in phytoremediation potential of Indian mustard exposed to nickel stress: a hydroponic study.
International journal of phytoremediation.
2015; 17(1-6):135-44. doi:
10.1080/15226514.2013.862206. [PMID: 25237724] - Hongrui Guo, Bangyuan Wu, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Jie Deng, Shuang Yin, Jian Li, Kun Tang. NiCl2-down-regulated antioxidant enzyme mRNA expression causes oxidative damage in the broiler(')s kidney.
Biological trace element research.
2014 Dec; 162(1-3):288-95. doi:
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International journal of toxicology.
2014 Nov; 33(6):498-505. doi:
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Aquatic toxicology (Amsterdam, Netherlands).
2014 Oct; 155(?):142-50. doi:
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Annales pharmaceutiques francaises.
2014 Sep; 72(5):348-62. doi:
10.1016/j.pharma.2014.03.004. [PMID: 25220231] - Faouzi Dahdouh, Maximilian Raane, Frank Thévenod, Wing-Kee Lee. Nickel-induced cell death and survival pathways in cultured renal proximal tubule cells: roles of reactive oxygen species, ceramide and ABCB1.
Archives of toxicology.
2014 Apr; 88(4):881-92. doi:
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BMC pharmacology & toxicology.
2014 Mar; 15(?):15. doi:
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Meditsina truda i promyshlennaia ekologiia.
2014; ?(6):35-9. doi:
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Natural product research.
2014; 28(18):1499-502. doi:
10.1080/14786419.2014.913240. [PMID: 24870880] - Andrea Cove-Smith, Christopher J Mulgrew, Olena Rudyk, Neelanjana Dutt, Linda M McLatchie, Michael J Shattock, Bruce M Hendry. Anti-proliferative actions of T-type calcium channel inhibition in Thy1 nephritis.
The American journal of pathology.
2013 Aug; 183(2):391-401. doi:
10.1016/j.ajpath.2013.04.029. [PMID: 23746655] - Jiřina Kročková, Peter Massányi, Alexander V Sirotkin, Norbert Lukáč, Anton Kováčik. Nickel-induced structural and functional alterations in porcine granulosa cells in vitro.
Biological trace element research.
2013 Aug; 154(2):190-5. doi:
10.1007/s12011-013-9733-5. [PMID: 23784734] - Ounassa Adjroud. The toxic effects of nickel chloride on liver, erythropoiesis, and development in Wistar albino preimplanted rats can be reversed with selenium pretreatment.
Environmental toxicology.
2013 May; 28(5):290-8. doi:
10.1002/tox.20719. [PMID: 21618677] - Bangyuan Wu, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Jianying Huang, Qin Luo, Yubing Deng, Hesong Wang, Juan Liu. Changes of the serum cytokine contents in broilers fed on diets supplemented with nickel chloride.
Biological trace element research.
2013 Feb; 151(2):234-9. doi:
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Journal of applied toxicology : JAT.
2013 Feb; 33(2):134-41. doi:
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Acta biochimica et biophysica Sinica.
2012 Apr; 44(4):330-8. doi:
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BMC genomics.
2011 Apr; 12(?):195. doi:
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Archives of environmental contamination and toxicology.
2011 Jan; 60(1):68-76. doi:
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Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2011 Jan; 25(1):14-8. doi:
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BMC plant biology.
2010 Nov; 10(?):257. doi:
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Rheumatology international.
2010 Jul; 30(9):1159-64. doi:
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The Journal of neuroscience : the official journal of the Society for Neuroscience.
2010 May; 30(21):7300-9. doi:
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Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.
2010 Apr; 155(4):503-8. doi:
10.1016/j.cbpa.2009.12.014. [PMID: 20044020] - X-W Wang, J-Y Gu, Z Li, Y-F Song, W-S Wu, Y-P Hou. Gestational age and dose influence on placental transfer of 63Ni in rats.
Placenta.
2010 Apr; 31(4):305-11. doi:
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Lupus.
2010 Mar; 19(3):262-7. doi:
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Journal of toxicology and environmental health. Part A.
2010; 73(8):529-39. doi:
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Comptes rendus biologies.
2009 Aug; 332(8):685-96. doi:
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Zhurnal evoliutsionnoi biokhimii i fiziologii.
2009 May; 45(3):319-28. doi:
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Fa yi xue za zhi.
2008 Dec; 24(6):429-32. doi:
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Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.
2008 Oct; 44(5):151-8. doi:
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Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2008 Sep; 43(7):625-32. doi:
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Chemico-biological interactions.
2008 Aug; 174(3):183-92. doi:
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Yao xue xue bao = Acta pharmaceutica Sinica.
2008 Feb; 43(2):224-6. doi:
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International immunology.
2007 Aug; 19(8):965-75. doi:
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Pediatric research.
2007 Jul; 62(1):54-9. doi:
10.1203/pdr.0b013e3180676d05. [PMID: 17515839] - Lakshmi Prasad, Tajdar Husain Khan, Tamanna Jahangir, Sarwat Sultana. Acorus calamus extracts and nickel chloride: prevention of oxidative damage and hyperproliferation response in rat kidney.
Biological trace element research.
2006 Oct; 113(1):77-92. doi:
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Plant physiology and biochemistry : PPB.
2006 May; 44(5-6):420-9. doi:
10.1016/j.plaphy.2006.06.002. [PMID: 16806955] - Syed Imam Rabbani, Kshama Devi, Salma Khanam, Noor Zahra. Citral, a component of lemongrass oil inhibits the clastogenic effect of nickel chloride in mouse micronucleus test system.
Pakistan journal of pharmaceutical sciences.
2006 Apr; 19(2):108-13. doi:
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