Robustaflavone (BioDeep_00000007927)
PANOMIX_OTCML-2023 natural product
代谢物信息卡片
化学式: C30H18O10 (538.0899928)
中文名称: 罗波斯塔双黄酮
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 75%
分子结构信息
SMILES: c1(cc(c2c(c1)oc(cc2=O)c1cc(c(cc1)O)c1c(c2c(cc1O)oc(cc2=O)c1ccc(cc1)O)O)O)O
InChI: InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)23-11-22(37)29-26(39-23)12-20(35)27(30(29)38)17-7-14(3-6-18(17)33)24-10-21(36)28-19(34)8-16(32)9-25(28)40-24/h1-12,31-35,38H
描述信息
A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-3 of the hydroxyphenyl ring and C-6 of the chromene ring. Isolated from Thuja orientalis and Rhus succedanea it exhibits antioxidant, cytotoxic and anti-hepatitis B activity.
同义名列表
2 个代谢物同义名
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:8881
- KEGG: C10179
- PubChem: 5281694
- Metlin: METLIN47517
- LipidMAPS: LMPK12040005
- KNApSAcK: C00001094
- CAS: 49620-13-5
- MoNA: MoNA002606
- MoNA: MoNA002605
- PMhub: MS000021442
- MetaboLights: MTBLC8881
- PubChem: 12365
- 3DMET: B03612
- NIKKAJI: J10.022F
- LOTUS: LTS0213241
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
67 个相关的物种来源信息
- 4011 - Anacardiaceae: LTS0213241
- 329095 - Callitropsis: LTS0213241
- 85954 - Callitropsis nootkatensis:
- 85954 - Callitropsis nootkatensis: 10.1016/S0031-9422(00)83535-9
- 85954 - Callitropsis nootkatensis: 10.1016/S0031-9422(00)83874-1
- 85954 - Callitropsis nootkatensis: LTS0213241
- 13414 - Chamaecyparis: LTS0213241
- 55961 - Clusiaceae: LTS0213241
- 3367 - Cupressaceae: LTS0213241
- 13468 - Cupressus: LTS0213241
- 2759 - Eukaryota: LTS0213241
- 89190 - Fokienia: LTS0213241
- 58227 - Garcinia: LTS0213241
- 1009474 - Garcinia multiflora: 10.1055/S-1999-13971
- 1009474 - Garcinia multiflora: LTS0213241
- 13100 - Juniperus: LTS0213241
- 884032 - Juniperus bermudiana: 10.1016/S0031-9422(00)83535-9
- 884032 - Juniperus bermudiana: LTS0213241
- 74578 - Luxemburgia: LTS0213241
- 1521260 - Lycopodiopsida: LTS0213241
- 3398 - Magnoliopsida: LTS0213241
- 56627 - Ochnaceae: LTS0213241
- 58019 - Pinopsida: LTS0213241
- 4012 - Rhus: 10.1016/0031-9422(74)80342-0
- 43850 - Schinus: LTS0213241
- 169191 - Schinus terebinthifolia: 10.1007/S10600-005-0008-Z
- 3246 - Selaginella: 10.1016/J.JEP.2015.01.031
- 3246 - Selaginella: 10.1021/NP990538M
- 3246 - Selaginella: LTS0213241
- 1353961 - Selaginella delicatula:
- 1353961 - Selaginella delicatula: 10.1016/J.JEP.2015.01.031
- 1353961 - Selaginella delicatula: 10.1021/NP990538M
- 1353961 - Selaginella delicatula: LTS0213241
- 50508 - Selaginella denticulata: 10.1515/ZNC-1994-3-417
- 50508 - Selaginella denticulata: LTS0213241
- 1353966 - Selaginella labordei: 10.1080/14786410802228736
- 1353966 - Selaginella labordei: LTS0213241
- 59777 - Selaginella lepidophylla:
- 59777 - Selaginella lepidophylla: 10.1007/978-1-4615-3476-1_53
- 59777 - Selaginella lepidophylla: 10.1021/JF8010432
- 59777 - Selaginella lepidophylla: LTS0213241
- 1715386 - Selaginella nothohybrida:
- 1715386 - Selaginella nothohybrida: 10.1016/J.JEP.2015.01.031
- 1715386 - Selaginella nothohybrida: LTS0213241
- 672198 - Selaginella pulvinata:
- 69996 - Selaginella selaginoides: 10.1515/ZNC-1994-3-416
- 69996 - Selaginella selaginoides: LTS0213241
- 137174 - Selaginella sinensis: 10.1248/BPB.24.311
- 137174 - Selaginella sinensis: LTS0213241
- 137178 - Selaginella tamariscina:
- 137178 - Selaginella tamariscina: 10.1016/J.BMC.2007.10.036
- 137178 - Selaginella tamariscina: LTS0213241
- 137179 - Selaginella willdenowii: 10.1016/0031-9422(95)00212-P
- 137179 - Selaginella willdenowii: LTS0213241
- 3245 - Selaginellaceae: LTS0213241
- 35493 - Streptophyta: LTS0213241
- 13726 - Thujopsis: LTS0213241
- 13727 - Thujopsis dolabrata: 10.1016/S0031-9422(00)83535-9
- 13727 - Thujopsis dolabrata: LTS0213241
- 43852 - Toxicodendron: LTS0213241
- 269721 - Toxicodendron succedaneum:
- 269721 - Toxicodendron succedaneum: 10.1016/0305-1978(85)90066-3
- 269721 - Toxicodendron succedaneum: 10.1016/S0960-894X(97)00422-8
- 269721 - Toxicodendron succedaneum: LTS0213241
- 58023 - Tracheophyta: LTS0213241
- 33090 - Viridiplantae: LTS0213241
- 257622 - Xanthocyparis: LTS0213241
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- C Emade Kwene, Anastasie E Tih, Bintou Abderamane, Rapheal T Ghogomu. Two new phenolic glycosides from the leaves of Garcinia epunctata Stapf.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2020 Jan; 75(1-2):51-56. doi:
10.1515/znc-2018-0217. [PMID: 32053496] - Ara Jo, Hyun Ji Yoo, Mina Lee. Robustaflavone Isolated from Nandina domestica Using Bioactivity-Guided Fractionation Downregulates Inflammatory Mediators.
Molecules (Basel, Switzerland).
2019 May; 24(9):. doi:
10.3390/molecules24091789. [PMID: 31072069] - Chun-Gu Wang, Wei-Na Yao, Bin Zhang, Jing Hua, Dong Liang, Heng-Shan Wang. Lung cancer and matrix metalloproteinases inhibitors of polyphenols from Selaginella tamariscina with suppression activity of migration.
Bioorganic & medicinal chemistry letters.
2018 08; 28(14):2413-2417. doi:
10.1016/j.bmcl.2018.06.024. [PMID: 29921475] - Iriny M Ayoub, Michal Korinek, Tsong-Long Hwang, Bing-Hung Chen, Fang-Rong Chang, Mohamed El-Shazly, Abdel Nasser B Singab. Probing the Antiallergic and Anti-inflammatory Activity of Biflavonoids and Dihydroflavonols from Dietes bicolor.
Journal of natural products.
2018 02; 81(2):243-253. doi:
10.1021/acs.jnatprod.7b00476. [PMID: 29381070] - Phi-Hung Nguyen, Da-Jung Ji, Yu-Ran Han, Jae-Sue Choi, Dong-Young Rhyu, Byung-Sun Min, Mi-Hee Woo. Selaginellin and biflavonoids as protein tyrosine phosphatase 1B inhibitors from Selaginella tamariscina and their glucose uptake stimulatory effects.
Bioorganic & medicinal chemistry.
2015 Jul; 23(13):3730-7. doi:
10.1016/j.bmc.2015.04.007. [PMID: 25907369] - Yasmin Silva Rizk, Alice Fischer, Marillin de Castro Cunha, Patrik Oening Rodrigues, Maria Carolina Silva Marques, Maria de Fátima Cepa Matos, Mônica Cristina Toffoli Kadri, Carlos Alexandre Carollo, Carla Cardozo Pinto de Arruda. In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella sellowii on Leishmania (Leishmania) amazonensis.
Memorias do Instituto Oswaldo Cruz.
2014 Dec; 109(8):1050-6. doi:
10.1590/0074-0276140312. [PMID: 25591109] - Wen-Jie Tan, Jia-Cheng Xu, Li Li, Ke-Li Chen. Bioactive compounds of inhibiting xanthine oxidase from Selaginella labordei.
Natural product research.
2009; 23(4):393-8. doi:
10.1080/14786410802228736. [PMID: 19296380]