S-Methylcysteine (BioDeep_00000000759)

Main id: BioDeep_00000019380

 

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


S-Methyl-L-cysteine, substrate for methionine sulfoxide reductase A

化学式: C4H9NO2S (135.0354)
中文名称: S-甲基-L-半胱氨酸, 半胱氨酸甲酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CSCC(C(=O)O)N
InChI: InChI=1S/C4H9NO2S/c1-8-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1

描述信息

S-methylcysteine is a cysteine derivative that is L-cysteine in which the hydrogen attached to the sulfur is replaced by a methyl group. It has a role as a human urinary metabolite and a plant metabolite. It is a tautomer of a S-methylcysteine zwitterion.
S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities.

同义名列表

37 个代谢物同义名

S-Methyl-L-cysteine, substrate for methionine sulfoxide reductase A; S-methylcysteine, hydrochloride, (L-Cys)-isomer; (2R)-2-azaniumyl-3-(methylsulfanyl)propanoate; (2R)-2-amino-3-(methylsulfanyl)propanoic acid; (R)-2-Amino-3-(methylmercapto)propionic acid; (2R)-2-amino-3-methylsulfanylpropanoic acid; (R)-2-amino-3-(methylthio)propanoic acid; 0DDF4489-1BF1-4858-9127-80A71A348EC8; S-methylcysteine, (DL-Cys)-isomer; S-methylcysteine, (L-Cys)-isomer; ALANINE, 3-(METHYLTHIO)-, L-; S-METHYL-L-CYSTEINE, (-)-; 3-(methylthio)-L-alanine; (-)-S-Methyl-L-cysteine; S-11C-methyl-L-cysteine; 3-(METHYLTHIO)ALANINE; L-Cysteine, S-methyl-; S-METHYL-(R)-CYSTEINE; L-CH3SCH2CH(NH2)COOH; S-Methyl-DL-cysteine; S-METHYLCYSTEINE, L-; S-Methyl-L-cysteine; L-S-Methyl-cysteine; S-N-Methylcysteine; Cysteine,s-methyl-; S-methyl-cysteine; S-methylcysteine; H-Cys(Me)-OH.HCl; L-Methylcysteine; UNII-A34I1H07YM; S-methyl-l-cys; Methylcysteine; H-Cys(Me)-OH; A34I1H07YM; Methylcysteine; L-S-Methylcysteine; S-Methyl-L-cysteine



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

24 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AIMP2, ALB, BCL2, CASP8, CAT, HPGDS, MSRA, ODC1, PTGS2
Peripheral membrane protein 2 GORASP1, PTGS2
Endoplasmic reticulum membrane 2 BCL2, PTGS2
Nucleus 6 AIMP2, ALB, BCL2, CASP8, MPO, PCNA
cytosol 12 AIMP2, ALB, BCL2, CASP8, CAT, GPT, GSR, HPGDS, MSRA, NGF, ODC1, TDO2
dendrite 1 NGF
nuclear body 1 PCNA
centrosome 2 ALB, PCNA
nucleoplasm 5 CASP8, HPGDS, MPO, MSRA, PCNA
Cell membrane 1 TNF
Lipid-anchor 1 MSRA
Cytoplasmic side 1 GORASP1
lamellipodium 1 CASP8
Golgi apparatus membrane 1 GORASP1
cell surface 1 TNF
Golgi apparatus 2 ALB, GORASP1
Golgi membrane 2 GORASP1, INS
neuronal cell body 1 TNF
synaptic vesicle 1 NGF
Cytoplasm, cytosol 1 AIMP2
Lysosome 1 MPO
plasma membrane 2 MSRA, TNF
Membrane 4 AIMP2, BCL2, CAT, MSRA
axon 1 NGF
caveola 1 PTGS2
extracellular exosome 7 ALB, CAT, GPT, GSR, MPO, MSRA, PCNA
endoplasmic reticulum 3 ALB, BCL2, PTGS2
extracellular space 7 ALB, IL10, IL6, INS, MPO, NGF, TNF
mitochondrion 5 BCL2, CASP8, CAT, GSR, MSRA
protein-containing complex 5 ALB, BCL2, CASP8, CAT, PTGS2
intracellular membrane-bounded organelle 4 CAT, HPGDS, MPO, MSRA
Microsome membrane 1 PTGS2
Secreted 5 ALB, IL10, IL6, INS, NGF
extracellular region 8 ALB, CAT, IL10, IL6, INS, MPO, NGF, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, CASP8
mitochondrial matrix 2 CAT, GSR
anchoring junction 1 ALB
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 GSR, TNF
actin cytoskeleton 1 MSRA
midbody 1 MSRA
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cell projection, lamellipodium 1 CASP8
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 1 CAT
cis-Golgi network 1 GORASP1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 MPO
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
ciliary basal body 1 ALB
chromatin 1 PCNA
phagocytic cup 1 TNF
cytoskeleton 1 CASP8
centriole 1 ALB
spindle pole 1 ALB
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
blood microparticle 1 ALB
endosome lumen 2 INS, NGF
cell body 1 CASP8
replication fork 1 PCNA
myelin sheath 1 BCL2
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 2 INS, NGF
endoplasmic reticulum lumen 4 ALB, IL6, INS, PTGS2
male germ cell nucleus 1 PCNA
platelet alpha granule lumen 1 ALB
transport vesicle 1 INS
azurophil granule lumen 1 MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GORASP1, INS
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
nuclear lamina 1 PCNA
phagocytic vesicle lumen 1 MPO
CD95 death-inducing signaling complex 1 CASP8
death-inducing signaling complex 1 CASP8
ripoptosome 1 CASP8
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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