trichodermin (BioDeep_00000007583)

 

Secondary id: BioDeep_00001870061


代谢物信息卡片


(4beta,12R)-12,13-epoxytrichothec-9-en-4-yl acetate

化学式: C17H24O4 (292.1674504)
中文名称: 木霉素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)OC1CC2OC3C=C(C)CCC3(C)C1(C)C21CO1
InChI: InChI=1S/C17H24O4/c1-10-5-6-15(3)12(7-10)21-14-8-13(20-11(2)18)16(15,4)17(14)9-19-17/h7,12-14H,5-6,8-9H2,1-4H3/t12-,13-,14-,15+,16-,17-/m1/s1

描述信息

A tetracyclic spiroepoxide which acts as an antifungal and protein synthesis inhibitor.
D009676 - Noxae > D011042 - Poisons > D014255 - Trichothecenes
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins

同义名列表

3 个代谢物同义名

trichodermin; (4beta,12R)-12,13-epoxytrichothec-9-en-4-yl acetate; MLS002693885



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Xiajun Yao, Jin Xie, Yanhua Qi, Bin Wang, Wenxia Fang, Gang Tao, Xiliang Jiang. [Screening and evaluation of the biocontrol efficacy of a Trichoderma brevicompactum strain and its metabolite trichodermin against banana Fusarium wilt]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 2024 Jan; 40(1):211-225. doi: 10.13345/j.cjb.230170. [PMID: 38258642]
  • Yunfan Bai, Yuran Gao, Xin Lu, Huiyu Wang. Lipidomics characterization of the alterations of Trichoderma brevicompactum membrane glycerophospholipids during the fermentation phase. Journal of industrial microbiology & biotechnology. 2019 Jun; 46(6):809-818. doi: 10.1007/s10295-019-02152-y. [PMID: 30847610]
  • R E Cardoza, S P McCormick, M G Malmierca, E R Olivera, N J Alexander, E Monte, S Gutiérrez. Effects of Trichothecene Production on the Plant Defense Response and Fungal Physiology: Overexpression of the Trichoderma arundinaceum tri4 Gene in T. harzianum. Applied and environmental microbiology. 2015 Sep; 81(18):6355-66. doi: 10.1128/aem.01626-15. [PMID: 26150463]
  • Xiaojun Xu, Jingli Cheng, Yong Zhou, Chulong Zhang, Xiaoming Ou, Weike Su, Jinhao Zhao, Guonian Zhu. Synthesis and antifungal activities of trichodermin derivatives as fungicides on rice. Chemistry & biodiversity. 2013 Apr; 10(4):600-11. doi: 10.1002/cbdv.201200135. [PMID: 23576346]
  • Xu-Ping Shentu, Wei-Ping Liu, Xiao-Huan Zhan, Xiao-Ping Yu, Chuan-Xi Zhang. The elicitation effect of pathogenic fungi on trichodermin production by Trichoderma brevicompactum. TheScientificWorldJournal. 2013; 2013(?):607102. doi: 10.1155/2013/607102. [PMID: 24385883]
  • Li-Wei Wang, Bai-Ge Xu, Jia-Ying Wang, Zhen-Zhu Su, Fu-Cheng Lin, Chu-Long Zhang, Christian P Kubicek. Bioactive metabolites from Phoma species, an endophytic fungus from the Chinese medicinal plant Arisaema erubescens. Applied microbiology and biotechnology. 2012 Feb; 93(3):1231-9. doi: 10.1007/s00253-011-3472-3. [PMID: 21814808]
  • Mohamed Anwar Bin-Umer, John E McLaughlin, Debaleena Basu, Susan McCormick, Nilgun E Tumer. Trichothecene mycotoxins inhibit mitochondrial translation--implication for the mechanism of toxicity. Toxins. 2011 12; 3(12):1484-501. doi: 10.3390/toxins3121484. [PMID: 22295173]
  • Petr Karlovsky. Biological detoxification of the mycotoxin deoxynivalenol and its use in genetically engineered crops and feed additives. Applied microbiology and biotechnology. 2011 Aug; 91(3):491-504. doi: 10.1007/s00253-011-3401-5. [PMID: 21691789]
  • Iwona Yike, Anne M Distler, Assem G Ziady, Dorr G Dearborn. Mycotoxin adducts on human serum albumin: biomarkers of exposure to Stachybotrys chartarum. Environmental health perspectives. 2006 Aug; 114(8):1221-6. doi: 10.1289/ehp.9064. [PMID: 16882529]
  • S N Kulikov, F K Alimova, N G Zakharova, S V Nemtsev, V P Varlamov. [Biological preparations with different mechanism of action for protecting potato against fungal diseases]. Prikladnaia biokhimiia i mikrobiologiia. 2006 Jan; 42(1):86-92. doi: . [PMID: 16521583]
  • S I Egorov, F K Alimova, N G Zakharova, I B Leshchinskaia. [Influence of Bacillus intermedius RNAse on growth-stimulating and antagonistic characteristics of Trichoderma harzianum]. Prikladnaia biokhimiia i mikrobiologiia. 1996 Sep; 32(5):554-6. doi: ". [PMID: 9011860]
  • . . . . doi: . [PMID: 22069741]