NCBI Taxonomy: 80383
Stachybotrys echinatus (ncbi_taxid: 80383)
found 52 associated metabolites at species taxonomy rank level.
Ancestor: Stachybotrys
Child Taxonomies: none taxonomy data.
Griseofulvin
Griseofulvin is only found in individuals that have used or taken this drug. It is an antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections. [PubChem]Griseofulvin is fungistatic, however the exact mechanism by which it inhibits the growth of dermatophytes is not clear. It is thought to inhibit fungal cell mitosis and nuclear acid synthesis. It also binds to and interferes with the function of spindle and cytoplasmic microtubules by binding to alpha and beta tubulin. It binds to keratin in human cells, then once it reaches the fungal site of action, it binds to fungal microtubes thus altering the fungal process of mitosis. D - Dermatologicals > D01 - Antifungals for dermatological use > D01B - Antifungals for systemic use > D01BA - Antifungals for systemic use D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use > D01AA - Antibiotics D000890 - Anti-Infective Agents > D000935 - Antifungal Agents C254 - Anti-Infective Agent > C514 - Antifungal Agent Griseofulvin(Gris-PEG; Grifulvin) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal drug.
trichodermin
A tetracyclic spiroepoxide which acts as an antifungal and protein synthesis inhibitor. D009676 - Noxae > D011042 - Poisons > D014255 - Trichothecenes D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
Griseofulvin
An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment. D - Dermatologicals > D01 - Antifungals for dermatological use > D01B - Antifungals for systemic use > D01BA - Antifungals for systemic use D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use > D01AA - Antibiotics D000890 - Anti-Infective Agents > D000935 - Antifungal Agents C254 - Anti-Infective Agent > C514 - Antifungal Agent CONFIDENCE Reference Standard (Level 1) relative retention time with respect to 9-anthracene Carboxylic Acid is 1.075 Griseofulvin(Gris-PEG; Grifulvin) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal drug.
4,6-dihydroxy-5-(3,7,11-trimethyl-10-oxododeca-2,6-dien-1-yl)-3h-2-benzofuran-1-one
(2r,6's)-2',4,6-trimethoxy-6'-methylspiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
4,6-dihydroxy-5-[(2e,6e)-3,7,11-trimethyl-10-oxododeca-2,6-dien-1-yl]-3h-2-benzofuran-1-one
(2'r,7'r,9'r,11'r)-1',2',5'-trimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0²,⁷]dodecan]-5'-en-11'-ol
1-{1-[2-({[1-(2-{[2-({[1-(2-{[2-({2-[(2r,2'r,4'as,6'r,8'as)-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-3,3',4',4'a,6',7',8,8'-octahydro-2'h-spiro[furo[2,3-e]isoindole-2,1'-naphthalen]-7-yl]-1-hydroxy-4-methanesulfinylbutylidene}amino)-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-4-(c-hydroxycarbonimidoyl)butanoyl)pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-4-(c-hydroxycarbonimidoyl)butanoyl)pyrrolidin-2-yl](hydroxy)methylidene}amino)-4-methylpentanoyl]pyrrolidine-2-carbonyl}pyrrolidine-2-carboxylic acid
C76H108N16O18S (1564.7747828000001)
1-(1-{2-[({1-[2-({2-[({1-[2-({2-[(2-{4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-3,3',4',4'a,6',7',8,8'-octahydro-2'h-spiro[furo[2,3-e]isoindole-2,1'-naphthalen]-7-yl}-1-hydroxy-4-methanesulfinylbutylidene)amino]-1-hydroxy-3-(3h-imidazol-4-yl)propylidene}amino)-4-(c-hydroxycarbonimidoyl)butanoyl]pyrrolidin-2-yl}(hydroxy)methylidene)amino]-1-hydroxy-3-(3h-imidazol-4-yl)propylidene}amino)-4-(c-hydroxycarbonimidoyl)butanoyl]pyrrolidin-2-yl}(hydroxy)methylidene)amino]-4-methylpentanoyl}pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid
C76H108N16O18S (1564.7747828000001)
2',4,6-trimethoxy-6'-methylspiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
(1s,13r,14s,17s,19r)-7,10-dihydroxy-1,14,18,18-tetramethyl-2-oxa-6-azapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-3(11),4(8),6,9-tetraen-17-yl acetate
C25H33NO5 (427.23586080000007)
5-[(2e,6e,10s)-10,11-dihydroxy-3,7,11-trimethyldodeca-2,6-dien-1-yl]-4,6-dihydroxy-3h-2-benzofuran-1-one
5-(10,11-dihydroxy-3,7,11-trimethyldodeca-2,6-dien-1-yl)-4,6-dihydroxy-3h-2-benzofuran-1-one
(1s,13r,14s,17s,19r)-10-hydroxy-6-(2-hydroxyethyl)-1,14,18,18-tetramethyl-7-oxo-2-oxa-6-azapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-3(11),4(8),9-trien-17-yl acetate
C27H37NO6 (471.26207420000003)
10-hydroxy-6-(2-hydroxyethyl)-1,14,18,18-tetramethyl-7-oxo-2-oxa-6-azapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-3,8,10-trien-17-yl acetate
C27H37NO6 (471.26207420000003)
7,10-dihydroxy-1,14,18,18-tetramethyl-2-oxa-6-azapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-3,6,8,10-tetraen-17-yl acetate
C25H33NO5 (427.23586080000007)