Juvenile hormone III (BioDeep_00000007550)

 

Secondary id: BioDeep_00000638404

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


methyl (2E,6E)-9-[(2R)-3,3-dimethyloxiran-2-yl]-3,7-dimethylnona-2,6-dienoate

化学式: C16H26O3 (266.1882)
中文名称: 保幼激素3
谱图信息: 最多检出来源 Homo sapiens(plant) 6.74%

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Juvenile hormone III. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/juvenile_hormone_iii (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000007550). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: COC(=O)/C=C(\C)CC/C=C(\C)CC[C@H]1OC1(C)C
InChI: InChI=1S/C16H26O3/c1-12(9-10-14-16(3,4)19-14)7-6-8-13(2)11-15(17)18-5/h7,11,14H,6,8-10H2,1-5H3/b12-7+,13-11+/t14-/m1/s1

描述信息

Juvenile hormone III is a member of the juvenile hormone family of compounds that is the methyl ester of (2E,6E)-9-[(2R)-3,3-dimethyloxiran-2-yl]-3,7-dimethylnona-2,6-dienoic acid. Juvenile hormone III is found in most insect species. It is an epoxide, an enoate ester, a fatty acid methyl ester and a juvenile hormone.

同义名列表

3 个代谢物同义名

juvenile hormone III; JH III; Juvenile hormone III



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(1)

代谢反应

5 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(4)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

26 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ARNT, CDC123, FDPS, HDAC1, HMGCS1, MVD, MVK, RPS6KB1, SP1
Peripheral membrane protein 2 ACHE, CYP1B1
Endoplasmic reticulum membrane 4 ACAT1, CYP1B1, HMGCR, HSP90B1
Nucleus 7 ACHE, ARNT, HDAC1, HSP90B1, RPS6KB1, SP1, USP1
cytosol 10 FDPS, HDAC1, HMGCS1, HSP90B1, MVD, MVK, PMVK, PRKCQ, RPS6KB1, USP1
nuclear body 1 ARNT
nucleoplasm 7 ARNT, ATP2B1, FDPS, HDAC1, RPS6KB1, SP1, USP1
RNA polymerase II transcription regulator complex 1 ARNT
Cell membrane 2 ACHE, ATP2B1
Multi-pass membrane protein 3 ACAT1, ATP2B1, HMGCR
Synapse 2 ACHE, ATP2B1
cell surface 2 ACHE, RPS6KB1
glutamatergic synapse 2 ATP2B1, RPS6KB1
Golgi apparatus 1 ACHE
Golgi membrane 1 INS
neuromuscular junction 1 ACHE
neuronal cell body 1 HDAC1
postsynapse 1 RPS6KB1
presynaptic membrane 1 ATP2B1
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 PMVK
plasma membrane 3 ACHE, ATP2B1, PRKCQ
synaptic vesicle membrane 1 ATP2B1
Membrane 8 ACAT1, ACHE, ATP2B1, CYP1B1, FDPS, HMGCR, HSP90B1, PMVK
basolateral plasma membrane 1 ATP2B1
extracellular exosome 4 ACAT1, ATP2B1, HSP90B1, PMVK
endoplasmic reticulum 3 ACAT1, HMGCR, HSP90B1
extracellular space 4 ACHE, GDF1, INS, SP1
perinuclear region of cytoplasm 3 ACHE, HSP90B1, RPS6KB1
mitochondrion 3 ACAT1, CYP1B1, RPS6KB1
protein-containing complex 2 HDAC1, HSP90B1
intracellular membrane-bounded organelle 3 ATP2B1, CYP1B1, MVK
Microsome membrane 1 CYP1B1
Secreted 3 ACHE, INS, SP1
extracellular region 4 ACHE, HSP90B1, INS, SP1
mitochondrial outer membrane 1 RPS6KB1
mitochondrial matrix 2 ACAT1, FDPS
Extracellular side 1 ACHE
transcription regulator complex 1 ARNT
centriolar satellite 1 PRKCQ
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
midbody 1 HSP90B1
heterochromatin 1 HDAC1
focal adhesion 1 HSP90B1
Peroxisome 3 FDPS, MVK, PMVK
basement membrane 1 ACHE
peroxisomal membrane 1 HMGCR
collagen-containing extracellular matrix 1 HSP90B1
lateral plasma membrane 1 ATP2B1
neuron projection 1 RPS6KB1
chromatin 3 ARNT, HDAC1, SP1
cell projection 1 ATP2B1
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
endosome lumen 1 INS
aryl hydrocarbon receptor complex 1 ARNT
Melanosome 1 HSP90B1
euchromatin 1 SP1
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
sperm plasma membrane 1 HSP90B1
Peroxisome membrane 1 HMGCR
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 HSP90B1, INS
transcription repressor complex 2 HDAC1, SP1
histone deacetylase complex 1 HDAC1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
NuRD complex 1 HDAC1
immunological synapse 2 ATP2B1, PRKCQ
aggresome 1 PRKCQ
Sarcoplasmic reticulum lumen 1 HSP90B1
Synapse, synaptosome 1 RPS6KB1
synaptic cleft 1 ACHE
Sin3-type complex 1 HDAC1
protein-DNA complex 1 SP1
endocytic vesicle lumen 1 HSP90B1
endoplasmic reticulum chaperone complex 1 HSP90B1
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE
nuclear aryl hydrocarbon receptor complex 1 ARNT


文献列表

  • Wenjing Cao, Fu Zhang, Haolin Li, Yimeng Zhang, Yongheng Zhang, Wenjie Zhang, Xiaxia Guo, Linxi Dong, Honghong Li, Dongqiang Zeng, Xuesheng Li, Xinling Yang. A short neuropeptide F analog (sNPF), III-2 may particularly regulate juvenile hormone III to influence Spodoptera frugiperda metamorphosis and development. Pesticide biochemistry and physiology. 2023 Dec; 197(?):105653. doi: 10.1016/j.pestbp.2023.105653. [PMID: 38072528]
  • Dov Borovsky, Robert G Hancock, Pierre Rougé, Charles A Powell, Robert G Shatters. Juvenile hormone affects the splicing of Culex quinquefasciatus early trypsin messenger RNA. Archives of insect biochemistry and physiology. 2018 Nov; 99(3):e21506. doi: 10.1002/arch.21506. [PMID: 30176073]
  • F Ibanez, X Tang, C Tamborindeguy. Bactericera cockerelli vitellogenin-6 like, a vitellogenin without a direct reproductive function?. Insect molecular biology. 2018 04; 27(2):166-176. doi: 10.1111/imb.12361. [PMID: 29143394]
  • Ratchanee Phatchana, Yordhathai Thongsri, Chavi Yenjai. Canangalias C-H, juvenile hormone III analogues from the roots of Cananga latifolia. Fitoterapia. 2016 Oct; 114(?):45-50. doi: 10.1016/j.fitote.2016.08.018. [PMID: 27575324]
  • S Lü, M Jiang, T Huo, X Li, Y Zhang. 3-hydroxy-3-methyl glutaryl coenzyme A reductase: an essential actor in the biosynthesis of cantharidin in the blister beetle Epicauta chinensis Laporte. Insect molecular biology. 2016 Feb; 25(1):58-71. doi: 10.1111/imb.12198. [PMID: 26566751]
  • Ahmad-Faris Seman-Kamarulzaman, Zeti-Azura Mohamed-Hussein, Chyan Leong Ng, Maizom Hassan. Novel NAD+-Farnesal Dehydrogenase from Polygonum minus Leaves. Purification and Characterization of Enzyme in Juvenile Hormone III Biosynthetic Pathway in Plant. PloS one. 2016; 11(8):e0161707. doi: 10.1371/journal.pone.0161707. [PMID: 27560927]
  • Heejung Yang, Hye Seong Kim, Eun Ju Jeong, Piseth Khiev, Young-Won Chin, Sang Hyun Sung. Plant-derived juvenile hormone III analogues and other sesquiterpenes from the stem bark of Cananga latifolia. Phytochemistry. 2013 Oct; 94(?):277-83. doi: 10.1016/j.phytochem.2013.06.010. [PMID: 23859262]
  • Shizuo G Kamita, Grant H Oshita, Peng Wang, Christophe Morisseau, Bruce D Hammock, Raja Sekhar Nandety, Bryce W Falk. Characterization of Hovi-mEH1, a microsomal epoxide hydrolase from the glassy-winged sharpshooter Homalodisca vitripennis. Archives of insect biochemistry and physiology. 2013 Aug; 83(4):171-9. doi: 10.1002/arch.21100. [PMID: 23704009]
  • Cheolho Sim, David L Denlinger. Juvenile hormone III suppresses forkhead of transcription factor in the fat body and reduces fat accumulation in the diapausing mosquito, Culex pipiens. Insect molecular biology. 2013 Feb; 22(1):1-11. doi: 10.1111/j.1365-2583.2012.01166.x. [PMID: 23121109]
  • Arti T Navare, Jaime G Mayoral, Marcela Nouzova, Fernando G Noriega, Facundo M Fernández. Rapid direct analysis in real time (DART) mass spectrometric detection of juvenile hormone III and its terpene precursors. Analytical and bioanalytical chemistry. 2010 Dec; 398(7-8):3005-13. doi: 10.1007/s00216-010-4269-4. [PMID: 20936260]
  • Yue-Shu Yu, Shan Xue, Jin-Cai Wu, Fang Wang, Jing-Lan Liu, Hainan Gu. Distribution of imidacloprid residues in different parts of rice plants and its effect on larvae and adult females of Chilo suppressalis (Lepidoptera: Pyralidae). Journal of economic entomology. 2007 Apr; 100(2):375-80. doi: 10.1603/0022-0493(2007)100[375:doirid]2.0.co;2. [PMID: 17461061]
  • Ai-Hua Wang, Jin-Cai Wu, Yue-Shu Yu, Jing-Lan Liu, Jiang-Fei Yue, Mei-Yue Wang. Selective insecticide-induced stimulation on fecundity and biochemical changes in Tryporyza incertulas (Lepidoptera: Pyralidae). Journal of economic entomology. 2005 Aug; 98(4):1144-9. doi: 10.1603/0022-0493-98.4.1144. [PMID: 16156564]
  • Y Fan, J C Gore, K O Redding, L D Vailes, M D Chapman, C Schal. Tissue localization and regulation by juvenile hormone of human allergen Bla g 4 from the German cockroach, Blattella germanica (L.). Insect molecular biology. 2005 Jan; 14(1):45-53. doi: 10.1111/j.1365-2583.2004.00530.x. [PMID: 15663774]
  • H Izadi, B Subrahmanyam. Effect of JH III and substituted oxime ethers on the in vitro protein and RNA synthesis in male accessory reproductive gland (MARG) of Spodoptera litura (F.). Communications in agricultural and applied biological sciences. 2005; 70(4):849-56. doi: ". [PMID: 16628927]
  • Kyung Jin Min, Nathan Jones, David W Borst, Mary Ann Rankin. Increased juvenile hormone levels after long-duration flight in the grasshopper, Melanoplus sanguinipes. Journal of insect physiology. 2004 Jun; 50(6):531-7. doi: 10.1016/j.jinsphys.2004.03.009. [PMID: 15183282]
  • Yuichi Nakahara, Yasushi Kanamori, Makoto Kiuchi, Manabu Kamimura. In vitro studies of hematopoiesis in the silkworm: cell proliferation in and hemocyte discharge from the hematopoietic organ. Journal of insect physiology. 2003 Oct; 49(10):907-16. doi: 10.1016/s0022-1910(03)00149-5. [PMID: 14511823]
  • Joseph C Dickens, James E Oliver, Benedict Hollister, John C Davis, Jerome A Klun. Breaking a paradigm: male-produced aggregation pheromone for the Colorado potato beetle. The Journal of experimental biology. 2002 Jul; 205(Pt 13):1925-33. doi: 10.1242/jeb.205.13.1925. [PMID: 12077169]
  • Y I N Silva Gunawardene, S S Tobe, W G Bendena, B K C Chow, K J Yagi, S-M Chan. Function and cellular localization of farnesoic acid O-methyltransferase (FAMeT) in the shrimp, Metapenaeus ensis. European journal of biochemistry. 2002 Jul; 269(14):3587-95. doi: 10.1046/j.1432-1033.2002.03048.x. [PMID: 12135499]
  • K Hanley, L G Kömüves, N M Bass, S S He, Y Jiang, D Crumrine, R Appel, M Friedman, J Bettencourt, K Min, P M Elias, M L Williams, K R Feingold. Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators. The Journal of investigative dermatology. 1999 Nov; 113(5):788-95. doi: 10.1046/j.1523-1747.1999.00743.x. [PMID: 10571735]
  • A M Schwartz, S M Paskewitz, A P Orth, M J Tesch, Y C Toong, W G Goodman. The lethal effects of Cyperus iria on Aedes aegypti. Journal of the American Mosquito Control Association. 1998 Mar; 14(1):78-82. doi: . [PMID: 9599328]
  • N Barbouche, F Couillaud, J Girardie, M Ammar, M H Ben Hammouda. [Effect of olive leaves (Olea europea) feeding on the in vitro JH III biosynthesis by the corpora allata in Schistocerca gregaria during vitellogenesis]. Archives de l'Institut Pasteur de Tunis. 1996 Jan; 73(1-2):9-12. doi: ". [PMID: 9412442]
  • E A Vladusic, O P Pignataro, L E Bussmann, E H Charreau. Regulation of the cholesterol ester cycle and progesterone synthesis by juvenile hormone in MA-10 Leydig tumor cells. The Journal of steroid biochemistry and molecular biology. 1995 Jan; 52(1):83-90. doi: 10.1016/0960-0760(94)00149-g. [PMID: 7857877]
  • W G Goodman. A simplified method for synthesizing juvenile hormone-protein conjugates. Journal of lipid research. 1990 Feb; 31(2):354-7. doi: 10.1016/s0022-2275(20)43222-5. [PMID: 2324654]