Tiliacorine (BioDeep_00000007529)
代谢物信息卡片
化学式: C36H36N2O5 (576.2624)
中文名称:
谱图信息:
最多检出来源 Mentha canadensis(plant) 100%
分子结构信息
SMILES: CN1CCC2=CC3=C4C=C2C1CC5=CC(=C(C=C5)O)C6=C(C=CC(=C6)CC7C8=C(O4)C(=C(C=C8CCN7C)OC)O3)OC
InChI: InChI=1S/C36H36N2O5/c1-37-11-9-22-17-31-32-19-24(22)27(37)15-20-5-7-29(39)25(13-20)26-14-21(6-8-30(26)40-3)16-28-34-23(10-12-38(28)2)18-33(41-4)35(42-31)36(34)43-32/h5-8,13-14,17-19,27-28,39H,9-12,15-16H2,1-4H3/t27-,28-/m0/s1
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:9597
- KEGG: C09667
- PubChem: 442369
- PubChem: 179494
- Metlin: METLIN67873
- ChEMBL: CHEMBL2017489
- CAS: 27073-72-9
- PMhub: MS000020918
- PubChem: 11857
- KNApSAcK: C00001925
- 3DMET: B03180
- NIKKAJI: J2.388.169A
- KNApSAcK: 9597
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Marutpong Detarya, Panupong Mahalapbutr, Orawan Waenphimai, Sonexai Kidoikhammouan, Somkid Janeklang, Kanlayanee Sawanyawisuth, Kulthida Vaeteewoottacharn, Wunchana Seubwai, Charupong Saengboonmee, Teerawut Thothaisong, Wachirachai Pabuprapap, Apichart Suksamrarn, Sopit Wongkham. Induction of apoptotic cell death of cholangiocarcinoma cells by tiliacorinine from Tiliacora triandra: A mechanistic insight.
Biochimica et biophysica acta. General subjects.
2023 Oct; 1867(12):130486. doi:
10.1016/j.bbagen.2023.130486
. [PMID: 37813201] - Shasank S Swain, Sanghamitra Pati, Tahziba Hussain. Quinoline heterocyclic containing plant and marine candidates against drug-resistant Mycobacterium tuberculosis: A systematic drug-ability investigation.
European journal of medicinal chemistry.
2022 Mar; 232(?):114173. doi:
10.1016/j.ejmech.2022.114173
. [PMID: 35168150] - Thanutchaporn Nutmakul, Kovit Pattanapanyasat, Noppamas Soonthornchareonnon, Kazuro Shiomi, Mihoko Mori, Sompop Prathanturarug. Speed of action and stage specificity of Bencha-loga-wichian, a Thai traditional antipyretic formulation, against Plasmodium falciparum and the chloroquine-potentiating activity of its active compounds, tiliacorinine and yanangcorinine.
Journal of ethnopharmacology.
2020 Aug; 258(?):112909. doi:
10.1016/j.jep.2020.112909
. [PMID: 32360802] - Somkid Janeklang, Archawin Nakaew, Kulthida Vaeteewoottacharn, Wunchana Seubwai, Patcharee Boonsiri, Gorkem Kismali, Apichart Suksamrarn, Seiji Okada, Sopit Wongkham. In vitro and in vivo antitumor activity of tiliacorinine in human cholangiocarcinoma.
Asian Pacific journal of cancer prevention : APJCP.
2014; 15(17):7473-8. doi:
10.7314/apjcp.2014.15.17.7473
. [PMID: 25227861] - Paul Klausmeyer, Thomas G McCloud, Dominic A Scudiero, Michael J Currens, John H Cardellina Ii, Robert H Shoemaker. Discovery and preliminary SAR of bisbenzylisoquinoline alkaloids as inducers of C/EBPα.
Bioorganic & medicinal chemistry.
2012 Aug; 20(15):4646-52. doi:
10.1016/j.bmc.2012.06.017
. [PMID: 22766217] - Sanya Sureram, Sarath P D Senadeera, Poonpilas Hongmanee, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop. Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters.
2012 Apr; 22(8):2902-5. doi:
10.1016/j.bmcl.2012.02.053
. [PMID: 22418278]