FA 4:0 (BioDeep_00000628670)

Main id: BioDeep_00000003106

Secondary id: BioDeep_00000405190, BioDeep_00000405471, BioDeep_00000866542, BioDeep_00000868797

PANOMIX_OTCML-2023 BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


2-methyl-propanoic acid

化学式: C4H8O2 (88.0524268)
中文名称: 丁酸, 异丁酸, 植物脂肪酸, 正丁酸
谱图信息: 最多检出来源 Homo sapiens(feces) 0.09%

分子结构信息

SMILES: CC(C)C(=O)O
InChI: InChI=1S/C4H8O2/c1-3(2)4(5)6/h3H,1-2H3,(H,5,6)

描述信息

D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists

同义名列表

13 个代谢物同义名

2-methyl-propanoic acid; ISOBUTYRIC ACID; FA 4:0; Fatty Acid, Vegetable; Ethylacetic acid; Butanoic acid; butyric acid; Butanoate; C4:0; Butyric acid; 2-Methylpropanoate; Butanoic acid; Isobutyric acid



数据库引用编号

34 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

25 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nannan Li, Lili Niu, Yao Liu, Yang Wang, Xiaomin Su, Ce Xu, Zanya Sun, Huishu Guo, Jingru Gong, Shun Shen. Taking SCFAs produced by Lactobacillus reuteri orally reshapes gut microbiota and elicits antitumor responses. Journal of nanobiotechnology. 2024 May; 22(1):241. doi: 10.1186/s12951-024-02506-4. [PMID: 38735933]
  • Yue Sun, Xiaolin Liu, Rongchun Wang, Rongmei Liu, Xuepeng Lv, Ying Ma, Qiming Li. Lacticaseibacillus rhamnosus HF01 fermented yogurt alleviated high-fat diet-induced obesity and hepatic steatosis via the gut microbiota-butyric acid-hepatic lipid metabolism axis. Food & function. 2024 Apr; 15(8):4475-4489. doi: 10.1039/d3fo04985j. [PMID: 38563737]
  • Lina Zhang, Zhiguo Ma, Xiaoxu Zhang, Jing Wang, Wenyan Tian, Yi Ren, Yajuan Liu, Ting Wang, Yiwei Li, Yuanyuan Liu, Wenke Shen, Ting Li, Jian Liu, Junbai Ma, Xiaoxia Zhang, Shaoqi Yang, Hao Wang. Butyrate alleviates alcoholic liver disease-associated inflammation through macrophage regulation and polarization via the HDAC1/miR-155 axis. International immunopharmacology. 2024 Apr; 131(?):111852. doi: 10.1016/j.intimp.2024.111852. [PMID: 38492338]
  • Jiayi Ding, Jiuyue Liu, Jinyan Chen, Xinyi Cheng, Huabin Cao, Xiaoquan Guo, Guoliang Hu, Yu Zhuang. Sodium butyrate alleviates free fatty acid-induced steatosis in primary chicken hepatocytes via the AMPK/PPARα pathway. Poultry science. 2024 Apr; 103(4):103482. doi: 10.1016/j.psj.2024.103482. [PMID: 38387286]
  • Bahar Kartal, Farika Nur Denizler-Ebiri, Mustafa Güven, Filiz Taşpınar, Hande Canpınar, Sedat Çetin, Tuğçe Karaduman, Serkan Küççüktürk, Javier Castresana, Mehmet Taşpınar. Exploring the combined anti-cancer effects of sodium butyrate and celastrol in glioblastoma cell lines: a novel therapeutic approach. Medical oncology (Northwood, London, England). 2024 Mar; 41(5):97. doi: 10.1007/s12032-024-02340-6. [PMID: 38532150]
  • Kanber Kara, Sena Yilmaz, Berrin Kocaoğlu Güçlü, Seyrani Demir. In vitro ruminal fermentation, core nutrient, fatty acids and mineral matter of pennyroyal (Mentha pulegium L.) herbage at different phenological stages. Veterinary medicine and science. 2024 03; 10(2):e1397. doi: 10.1002/vms3.1397. [PMID: 38450960]
  • Zuzanna Majka, Barbara Zapala, Agnieszka Krawczyk, Krzysztof Czamara, Joanna Mazurkiewicz, Ewa Stanek, Izabela Czyzynska-Cichon, Mariusz Kepczynski, Dominika Salamon, Tomasz Gosiewski, Agnieszka Kaczor. Direct oral and fiber-derived butyrate supplementation as an anti-obesity treatment via different targets. Clinical nutrition (Edinburgh, Scotland). 2024 03; 43(3):869-880. doi: 10.1016/j.clnu.2024.02.009. [PMID: 38367596]
  • Yuanqing Hua, Xianghuan Si, Dongna Li, Zhen Li, Tianshu Xu. Hydrogen peroxide fluorescent probe-monitored butyric acid inhibition of the ferroptosis process. Luminescence : the journal of biological and chemical luminescence. 2024 Mar; 39(3):e4715. doi: 10.1002/bio.4715. [PMID: 38506397]
  • Chia-Liang Lin, Tsung-Ho Ying, Shun-Fa Yang, Chu-Liang Lin, Hui-Ling Chiou, Yi-Hsien Hsieh. Magnolin targeting of the JNK/Sp1/MMP15 signaling axis suppresses cervical cancer microenvironment and metastasis via microbiota modulation. Cancer letters. 2024 Feb; 583(?):216584. doi: 10.1016/j.canlet.2023.216584. [PMID: 38123014]
  • Ming-Hui Li, Xu Liu, Yu-Liang Xie, Xiao-Guang Tang, Liao-Fan Song, Fan-Rong Zhao, Yu-Jing Chen, Chao Guo, Wei-Fang Zhang, Tian-Tian Zhu. Sodium butyrate alleviates right ventricular hypertrophy in pulmonary arterial hypertension by inhibiting H19 and affecting the activation of let-7g-5p/IGF1 receptor/ERK. European journal of pharmacology. 2024 Feb; 965(?):176315. doi: 10.1016/j.ejphar.2024.176315. [PMID: 38176636]
  • Maiara S Marchiori, Diovani Paiano, Emerson Zatti, Lara Tarasconi, Cassio Ficagna, Marco A F D Amaral, Carine F Milarch, Vitor W Horn, Ricardo E Mendes, Gabriela M Galli, Marcelo Vedovatto, Aleksandro S Da Silva. Butyric acid glycerides as substitutes for antibiotics as growth enhancers in the diet of nursery piglets. Research in veterinary science. 2024 Feb; 167(?):105110. doi: 10.1016/j.rvsc.2023.105110. [PMID: 38150942]
  • Hangping Chen, Yifan Qian, Chensheng Jiang, Leilei Tang, Jiawen Yu, Lingdi Zhang, Yiyang Dai, Guojun Jiang. Butyrate ameliorated ferroptosis in ulcerative colitis through modulating Nrf2/GPX4 signal pathway and improving intestinal barrier. Biochimica et biophysica acta. Molecular basis of disease. 2024 02; 1870(2):166984. doi: 10.1016/j.bbadis.2023.166984. [PMID: 38061600]
  • Cristina Sebastià, Josep M Folch, Maria Ballester, Jordi Estellé, Magí Passols, María Muñoz, Juan M García-Casco, Ana I Fernández, Anna Castelló, Armand Sánchez, Daniel Crespo-Piazuelo. Interrelation between gut microbiota, SCFA, and fatty acid composition in pigs. mSystems. 2024 Jan; 9(1):e0104923. doi: 10.1128/msystems.01049-23. [PMID: 38095419]
  • Xianbin Meng, Qinglong Shu. Novel primers to identify a wider diversity of butyrate-producing bacteria. World journal of microbiology & biotechnology. 2024 Jan; 40(2):76. doi: 10.1007/s11274-023-03872-1. [PMID: 38252387]
  • Zixin Yang, Diming Tan, Weiwen Chen, Jun Hu, Rui Huang, Xiyang Wu, Milen I Georgiev, Weibin Bai, Lingmin Tian. Fermentation characteristics and prebiotic potential of enzymatically synthesized butyryl-fructooligosaccharides. Carbohydrate polymers. 2024 Jan; 324(?):121486. doi: 10.1016/j.carbpol.2023.121486. [PMID: 37985044]
  • P R Manhone, J C Lopes, R S Alexandre, P A M Lima, S O Lopes, L H G Mengarda, T Mello. Plant growth regulators and mobilization of reserves in imbibition phases of yellow passion fruit. Brazilian journal of biology = Revista brasleira de biologia. 2024; 84(?):e273999. doi: 10.1590/1519-6984.273999. [PMID: 38451628]
  • Yiming Ni, Liangyin Cai, Xiaojun Gou, Wenjie Li, Mingmei Zhou, Ying Huang. Therapeutic effect of Sanhua decoction on rats with middle cerebral artery occlusion and the associated changes in gut microbiota and short-chain fatty acids. PloS one. 2024; 19(2):e0298148. doi: 10.1371/journal.pone.0298148. [PMID: 38363776]
  • Yifan Cui, Yingzhuo Zhou, Yan Li, Jieying Wang, Daotong Li, Fang Chen. Chinese Yam and Its Active Components Regulate the Structure of Gut Microbiota and Indole-like Metabolites in Anaerobic Fermentation In Vitro. Nutrients. 2023 Dec; 15(24):. doi: 10.3390/nu15245112. [PMID: 38140371]
  • Yuhao Han, Xinyan Qu, Haoyuan Geng, Lei Wang, Zihan Zhu, Yaqi Zhang, Xiaoqing Cui, Heng Lu, Xiao Wang, Panpan Chen, Quanbo Wang, Chenglong Sun. Isotope-Coded On-Tissue Derivatization for Quantitative Mass Spectrometry Imaging of Short-Chain Fatty Acids in Biological Tissues. Analytical chemistry. 2023 12; 95(48):17622-17628. doi: 10.1021/acs.analchem.3c03308. [PMID: 37997359]
  • Moldir Koilybayeva, Zhanserik Shynykul, Gulbaram Ustenova, Krzysztof Waleron, Joanna Jońca, Kamilya Mustafina, Akerke Amirkhanova, Yekaterina Koloskova, Raushan Bayaliyeva, Tamila Akhayeva, Mereke Alimzhanova, Aknur Turgumbayeva, Gulden Kurmangaliyeva, Aigerim Kantureyeva, Dinara Batyrbayeva, Zhazira Alibayeva. Gas Chromatography-Mass Spectrometry Profiling of Volatile Metabolites Produced by Some Bacillus spp. and Evaluation of Their Antibacterial and Antibiotic Activities. Molecules (Basel, Switzerland). 2023 Nov; 28(22):. doi: 10.3390/molecules28227556. [PMID: 38005278]
  • Wenjie Xu, Shanshan Xu, Ruobing Feng, Li Zeng. Yunpi Tongbian Fang alleviates slow transit constipation induced by loperamide by regulating intestinal microbiota and short-chain fatty acids in rats. Cellular and molecular biology (Noisy-le-Grand, France). 2023 Oct; 69(10):23-29. doi: 10.14715/cmb/2023.69.10.4. [PMID: 37953588]
  • Haitao Zeng, Mengjiao Chen, Tao Zheng, Qi Tang, Hao Xu. Metabolomics Analysis Reveals the Accumulation Patterns of Flavonoids and Volatile Compounds in Camellia oleifera Petals with Different Color. Molecules (Basel, Switzerland). 2023 Oct; 28(21):. doi: 10.3390/molecules28217248. [PMID: 37959668]
  • Li-Na Guo, Lin Lu, Xue-Rui Dong, Feng-Lu Zhang, Peng Yan, Zhi-Qiang Dong. Effects of gibberellic acid, kinetin and indole butyric acid mixture on sorghum salinity tolerance and grain yield in saline-alkali coastal zone. Ying yong sheng tai xue bao = The journal of applied ecology. 2023 Sep; 34(9):2405-2412. doi: 10.13287/j.1001-9332.202309.016. [PMID: 37899106]
  • Liyuan Wang, Hongmei Mao, Shi Shen, Xi Chen, Tonglei Wang, Jinpeng Zhao, Chao Han, Junsheng Huo. [Repairing effects of Lactobacillus acidophilus on ceftriaxone-induced intestinal dysbacteriosis in mice]. Wei sheng yan jiu = Journal of hygiene research. 2023 Sep; 52(5):749-755. doi: 10.19813/j.cnki.weishengyanjiu.2023.05.010. [PMID: 37802897]
  • Giuseppe Celano, Francesco Maria Calabrese, Giuseppe Riezzo, Benedetta D'Attoma, Antonia Ignazzi, Martina Di Chito, Annamaria Sila, Sara De Nucci, Roberta Rinaldi, Michele Linsalata, Mirco Vacca, Carmen Aurora Apa, Maria De Angelis, Gianluigi Giannelli, Giovanni De Pergola, Francesco Russo. Effects of a Very-Low-Calorie Ketogenic Diet on the Fecal and Urinary Volatilome in an Obese Patient Cohort: A Preliminary Investigation. Nutrients. 2023 Aug; 15(17):. doi: 10.3390/nu15173752. [PMID: 37686784]
  • Xiao-Na Huang, Chen-Yang Zhu, Yu-Zhen Li, Chun-Hui Jin. [Weidiao-3 Mixture Improves the Clinical Efficacy of Immunotherapy for Advanced Gastric Cancer by Regulating Intestinal Flora]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 2023 Aug; 45(4):581-590. doi: 10.3881/j.issn.1000-503x.15496. [PMID: 37654138]
  • Ziwei Wang, Wan Shu, Rong Zhao, Yan Liu, Hongbo Wang. Sodium butyrate induces ferroptosis in endometrial cancer cells via the RBM3/SLC7A11 axis. Apoptosis : an international journal on programmed cell death. 2023 08; 28(7-8):1168-1183. doi: 10.1007/s10495-023-01850-4. [PMID: 37170022]
  • Siming Wang, Qihan Cai, Lu Xu, Yanan Sun, Mengmeng Wang, Yu Wang, Lili Zhang, Keqing Li, Zhiyu Ni. Isoalantolactone relieves depression-like behaviors in mice after chronic social defeat stress via the gut-brain axis. Psychopharmacology. 2023 Aug; 240(8):1775-1787. doi: 10.1007/s00213-023-06413-8. [PMID: 37400661]
  • Min-A Ahn, Jinsu Lee, Tae Kyung Hyun. Histone Deacetylase Inhibitor, Sodium Butyrate-Induced Metabolic Modulation in Platycodon grandiflorus Roots Enhances Anti-Melanogenic Properties. International journal of molecular sciences. 2023 Jul; 24(14):. doi: 10.3390/ijms241411804. [PMID: 37511563]
  • Xiaoying Liu, Chenxu Wang, Yumeng Wang, Chaohui Wang, Xi Sun, Yufei Zhu, Xiaojun Yang, Lixin Zhang, Yanli Liu. Age-associated changes in the growth development of abdominal fat and their correlations with cecal gut microbiota in broiler chickens. Poultry science. 2023 Jun; 102(9):102900. doi: 10.1016/j.psj.2023.102900. [PMID: 37406441]
  • Ling Zhang, Ning Chen, Libin Zhan, Tingting Bi, Wen Zhou, Lijing Zhang, Lianlian Zhu. Erchen Decoction alleviates obesity-related hepatic steatosis via modulating gut microbiota-drived butyric acid contents and promoting fatty acid β-oxidation. Journal of ethnopharmacology. 2023 Jun; ?(?):116811. doi: 10.1016/j.jep.2023.116811. [PMID: 37336336]
  • Ming-Min Xu, Yu Guo, Ying Chen, Wei Zhang, Lu Wang, Ying Li. Electro-acupuncture promotes gut motility and alleviates functional constipation by regulating gut microbiota and increasing butyric acid generation in mice. Journal of integrative medicine. 2023 Jun; ?(?):. doi: 10.1016/j.joim.2023.05.003. [PMID: 37331860]
  • Qingsong Tang, Wenxue Li, Zhongxiang Ren, Qi Ding, Xie Peng, Zhiru Tang, Jiaman Pang, Yetong Xu, Zhihong Sun. Different Fatty Acid Supplementation in Low-Protein Diets Regulate Nutrient Utilization and Lipid and Amino Acid Metabolism in Weaned Pigs Model. International journal of molecular sciences. 2023 May; 24(10):. doi: 10.3390/ijms24108501. [PMID: 37239844]
  • Wenxia Jiang, Jianjun Chen, Lei Gong, Fang Liu, Huan Zhao, Zhiwen Yan, Yingli Li, Jie Zhang, Mi Xiao, Jun Mu. Microbiota-derived short-chain fatty acids may participate in post-stroke depression by regulating host's lipid metabolism. Journal of psychiatric research. 2023 May; 161(?):426-434. doi: 10.1016/j.jpsychires.2023.03.032. [PMID: 37031497]
  • Zhili Chen, Ling Xin, Liu Yang, Meijie Xu, Fei Li, Min Zhou, Tao Yan. Butyrate promotes post-stroke outcomes in aged mice via interleukin-22. Experimental neurology. 2023 05; 363(?):114351. doi: 10.1016/j.expneurol.2023.114351. [PMID: 36804553]
  • GuoYan Wang, SenLin Qin, Lei Chen, HuiJun Geng, YiNing Zheng, Chao Xia, JunHu Yao, Lu Deng. Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling. Cell death & disease. 2023 04; 14(4):292. doi: 10.1038/s41419-023-05778-0. [PMID: 37185889]
  • Md Karim Uddin, Md Rayhan Mahmud, Shah Hasan, Olli Peltoniemi, Claudio Oliviero. Dietary micro-fibrillated cellulose improves growth, reduces diarrhea, modulates gut microbiota, and increases butyrate production in post-weaning piglets. Scientific reports. 2023 04; 13(1):6194. doi: 10.1038/s41598-023-33291-z. [PMID: 37062780]
  • Yongjie Xu, Sijia Wei, Liying Zhu, Changyudong Huang, Tingting Yang, Shuang Wang, Yiqiong Zhang, Yunfeng Duan, Xing Li, Zhengrong Wang, Wei Pan. Low expression of the intestinal metabolite butyric acid and the corresponding memory pattern regulate HDAC4 to promote apoptosis in rat hippocampal neurons. Ecotoxicology and environmental safety. 2023 Mar; 253(?):114660. doi: 10.1016/j.ecoenv.2023.114660. [PMID: 36812872]
  • Babita Shashni, Yuya Tajika, Yutaka Ikeda, Yuji Nishikawa, Yukio Nagasaki. Self-assembling polymer-based short chain fatty acid prodrugs ameliorate non-alcoholic steatohepatitis and liver fibrosis. Biomaterials. 2023 Feb; 295(?):122047. doi: 10.1016/j.biomaterials.2023.122047. [PMID: 36840994]
  • Ashokkumar Natarajan, Dharani Selvam, Kalaiarasan Palaniappan, Akshaya Subbaiah Balamurali, Chandrasekaran Perumal, Rameshkumar Durai, Shakila Sadasivam, Akino Asokan, Ramadass Sivalingam, Ashok Subiramaniyan. Standardization of the Optimum Effects of Indole 3-Butyric Acid (IBA) to Control Root Knot Nematode, Meloidogyne enterolobii, in Guava (Psidium guajava L.). Molecules (Basel, Switzerland). 2023 Feb; 28(4):. doi: 10.3390/molecules28041839. [PMID: 36838832]
  • Wanyi Zhou, Wenyang Tao, Mingzhe Wang, Wei Liu, Jianrong Xing, Ying Yang. Dendrobium officinale Xianhu 2 polysaccharide helps forming a healthy gut microbiota and improving host immune system: An in vitro and in vivo study. Food chemistry. 2023 Feb; 401(?):134211. doi: 10.1016/j.foodchem.2022.134211. [PMID: 36122490]
  • Huiling Wei, Chunyang Yu, Chun Zhang, Yi Ren, Li Guo, Ting Wang, Feifei Chen, Yiwei Li, Xiaoxia Zhang, Hao Wang, Juan Liu. Butyrate ameliorates chronic alcoholic central nervous damage by suppressing microglia-mediated neuroinflammation and modulating the microbiome-gut-brain axis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Jan; 160(?):114308. doi: 10.1016/j.biopha.2023.114308. [PMID: 36709599]
  • Ying He, Bang Cheng, Bing-Jian Guo, Zheng Huang, Jing-Hua Qin, Qian-Yi Wang, Lin-Lin Feng, Yun-Yuan Nong, Dan Zhu, Hong-Wei Guo, Zhi-Heng Su. Metabonomics and 16S rRNA gene sequencing to study the therapeutic mechanism of Danggui Sini decoction on collagen-induced rheumatoid arthritis rats with Cold Bi syndrome. Journal of pharmaceutical and biomedical analysis. 2023 Jan; 222(?):115109. doi: 10.1016/j.jpba.2022.115109. [PMID: 36270097]
  • Hailong Dong, Xiushuang Chen, Xiaoxiao Zhao, Chenxi Zhao, Khalid Mehmood, Muhammad Fakhar-E-Alam Kulyar, Zeeshan Ahmad Bhutta, Jiangyong Zeng, Shah Nawaz, Qingxia Wu, Kun Li. Intestine microbiota and SCFAs response in naturally Cryptosporidium-infected plateau yaks. Frontiers in cellular and infection microbiology. 2023; 13(?):1105126. doi: 10.3389/fcimb.2023.1105126. [PMID: 36936759]
  • Xiushuang Chen, Xiaoxiao Zhao, Chenxi Zhao, Hassan Ashfaq, Muhammad Fakhar-E-Alam Kulyar, Zeeshan Ahmad Bhutta, Muhammad Muddassir Ali, Muhammad Khalid Mansoor, Kun Li. Cryptosporidium infection induced the dropping of SCFAS and dysbiosis in intestinal microbiome of Tibetan pigs. Microbial pathogenesis. 2023 Jan; 174(?):105922. doi: 10.1016/j.micpath.2022.105922. [PMID: 36462579]
  • Ning Yang, Tongtong Lan, Yisa Han, Haifeng Zhao, Chuhui Wang, Zhen Xu, Zhao Chen, Meng Tao, Hui Li, Yang Song, Xuezhen Ma. Tributyrin alleviates gut microbiota dysbiosis to repair intestinal damage in antibiotic-treated mice. PloS one. 2023; 18(7):e0289364. doi: 10.1371/journal.pone.0289364. [PMID: 37523400]
  • Huiyan Ma, Libo Yang, Yajuan Liu, Ru Yan, Rui Wang, Peng Zhang, Zhixia Bai, Yuanyuan Liu, Yi Ren, Yiwei Li, Xin Jiang, Ting Wang, Ping Ma, Qining Zhang, Aifei Li, Mixue Guo, Xiaoxia Zhang, Shaobin Jia, Hao Wang. Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE-/- mice. PloS one. 2023; 18(3):e0282685. doi: 10.1371/journal.pone.0282685. [PMID: 36888629]
  • Shin Myung Kim, Jee Young Kim, Jaewon Park, Eun Hee Bae, Jae-Shin Kang, Ka Young Kim, Yoon-E Choi. Volatile fatty acid-treated mixotrophic cultivation of lipid/carbohydrate-rich cyanobacterial species, Pseudanabaena mucicola GO0704, for the enhancement of biofuel production. Bioresource technology. 2023 Jan; 367(?):128066. doi: 10.1016/j.biortech.2022.128066. [PMID: 36202284]
  • N V Kim, V A Zotov, V A Alekseev, S A Sheveleva. [The study of the content of short-chain fatty acids in the intestine of people with lipid metabolism disorders]. Voprosy pitaniia. 2023; 92(2):18-25. doi: 10.33029/0042-8833-2023-92-2-18-25. [PMID: 37346016]
  • Yifan Liang, Huijuan Zhang, Li Tian, Ce Shi, Yanyan Zheng, Jinfeng Wang, Yuqing Tan, Yongkang Luo, Hui Hong. Gut microbiota and metabolic profile as affected by Maillard reaction products derived from bighead carp meat hydrolysates with galactose and galacto-oligosaccharides during in vitro pig fecal fermentation. Food chemistry. 2023 Jan; 398(?):133905. doi: 10.1016/j.foodchem.2022.133905. [PMID: 35969991]
  • Yue Yu, Yuan-Yuan Jia, Hong-Jun Li. Sodium butyrate improves mitochondrial function and kidney tissue injury in diabetic kidney disease via the AMPK/PGC-1α pathway. Renal failure. 2023; 45(2):2287129. doi: 10.1080/0886022x.2023.2287129. [PMID: 38073119]
  • Qing Xiao, Li Zhao, Chang Jiang, Yanjin Zhu, Jizhou Zhang, Juan Hu, Guozeng Wang. Polysaccharides from Pseudostellaria heterophylla modulate gut microbiota and alleviate syndrome of spleen deficiency in rats. Scientific reports. 2022 11; 12(1):20217. doi: 10.1038/s41598-022-24329-9. [PMID: 36418343]
  • Mina Sadat Izadi, Farzaneh Eskandari, Fatemeh Binayi, Mina Salimi, Fatemeh Sadat Rashidi, Mehdi Hedayati, Leila Dargahi, Hossein Ghanbarian, Homeira Zardooz. Oxidative and endoplasmic reticulum stress develop adverse metabolic effects due to the high-fat high-fructose diet consumption from birth to young adulthood. Life sciences. 2022 Nov; 309(?):120924. doi: 10.1016/j.lfs.2022.120924. [PMID: 36063978]
  • Bing Zhang, Zhuoting Chen, Qixue Sun, Jianxiu Liu. Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.). BMC plant biology. 2022 Oct; 22(1):503. doi: 10.1186/s12870-022-03885-2. [PMID: 36289454]
  • Basim R Al Shammari. Antioxidant, Antimicrobial and In Silico NADPH Oxidase Inhibition of Chemically-Analyzed Essential Oils Derived from Ballota deserti (Noë) Jury. Molecules (Basel, Switzerland). 2022 Oct; 27(19):. doi: 10.3390/molecules27196636. [PMID: 36235177]
  • Yi Ren, Xiaoxia Zhang, Fang He, Ting Bao, Ting Wang, Yiwei Li, Rui Wang, Hao Wang, Shaoqi Yang. [Butyrate increases the monocytic myeloid-derived suppressor cells and promotes the secretion of anti-inflammatory cytokines in mice with alcoholic liver disease]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 2022 Oct; 38(10):865-871. doi: ". [PMID: 36163616]
  • Jana Štefániková, Július Árvay, Simona Kunová, Przemysław Łukasz Kowalczewski, Miroslava Kačániová. Aroma profile and lactic acid bacteria characteristic of traditional Slovak cheese 'May bryndza'. Food science and technology international = Ciencia y tecnologia de los alimentos internacional. 2022 Oct; 28(7):580-591. doi: 10.1177/10820132211039916. [PMID: 34515545]
  • He Xiao, Guo-Liang Cheng, Bing Li, Xian-Zhen Wang, Ran-Ran Kong, Li-Hong Pan, Gui-Min Zhang. [Mechanism of pathogenesis of Jingfang Mixture in intervention of chronic spontaneous urticaria based on serum metabolomics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2022 Oct; 47(20):5488-5493. doi: 10.19540/j.cnki.cjcmm.20220610.401. [PMID: 36471964]
  • Yuyang Tian, Yuqi Huang, Xiaohong Zhang, Gang Tang, Yunhao Gao, Zhiyuan Zhou, Yan Li, Huachen Wang, Xueyang Yu, Xuan Li, Yulu Liu, Guangyao Yan, Jialu Wang, Yongsong Cao. Self-Assembled Nanoparticles of a Prodrug Conjugate Based on Pyrimethanil for Efficient Plant Disease Management. Journal of agricultural and food chemistry. 2022 Sep; 70(38):11901-11910. doi: 10.1021/acs.jafc.2c04489. [PMID: 36111893]
  • Hong-Ren Yu, Jiunn-Ming Sheen, Chih-Yao Hou, I-Chun Lin, Li-Tung Huang, You-Lin Tain, Hsin-Hsin Cheng, Yun-Ju Lai, Yu-Ju Lin, Mao-Meng Tiao, Ching-Chou Tsai. Effects of Maternal Gut Microbiota-Targeted Therapy on the Programming of Nonalcoholic Fatty Liver Disease in Dams and Fetuses, Related to a Prenatal High-Fat Diet. Nutrients. 2022 Sep; 14(19):. doi: 10.3390/nu14194004. [PMID: 36235659]
  • Fengjiao Li, Yun Wu, Yujie Yan, Saizhi Wu, Jingyu Zhu, Gaihua Zhang, Peng Zhang, Lianwen Yuan, Yong Zeng, Zhonghua Liu. Transcriptomic landscape of sodium butyrate-induced growth inhibition of human colorectal cancer organoids. Molecular omics. 2022 09; 18(8):754-764. doi: 10.1039/d2mo00127f. [PMID: 35837877]
  • Wen-Lung Chang, Pei-Yi Liu, Shu-Lan Yeh, Huei-Jane Lee. Effects of Dried Onion Powder and Quercetin on Obesity-Associated Hepatic Menifestation and Retinopathy. International journal of molecular sciences. 2022 Sep; 23(19):. doi: 10.3390/ijms231911091. [PMID: 36232387]
  • Hai-Quan Yue, Peng-Fei Xu, Yi-Dan Guo, Jing Qi, Rui-Min Liu, De-He Li. Sodium butyrate inhibits oral squamous cell carcinoma proliferation and invasion by regulating the HDAC1/HSPB7 axis. Neoplasma. 2022 Sep; 69(5):1029-1040. doi: 10.4149/neo_2022_220311n270. [PMID: 35652621]
  • Kunli Wang, Yuxiao Wang, Si Chen, Junlian Gu, Yuanying Ni. Insoluble and Soluble Dietary Fibers from Kiwifruit (Actinidia deliciosa) Modify Gut Microbiota to Alleviate High-Fat Diet and Streptozotocin-Induced TYPE 2 Diabetes in Rats. Nutrients. 2022 Aug; 14(16):. doi: 10.3390/nu14163369. [PMID: 36014875]
  • Wangxin Liu, Xianliang Luo, Yang Tao, Ying Huang, Minjie Zhao, Jiahui Yu, Fengqin Feng, Wei Wei. Ultrasound enhanced butyric acid-lauric acid designer lipid synthesis: Based on artificial neural network and changes in enzymatic structure. Ultrasonics sonochemistry. 2022 Aug; 88(?):106100. doi: 10.1016/j.ultsonch.2022.106100. [PMID: 35908344]
  • Xiujing Dou, Di Yan, Ziwen Ma, Nan Gao, Anshan Shan. Sodium butyrate alleviates LPS-induced kidney injury via inhibiting TLR2/4 to regulate rBD2 expression. Journal of food biochemistry. 2022 Jul; 46(7):e14126. doi: 10.1111/jfbc.14126. [PMID: 35322444]
  • Juan Liu, Wenting Zhou, Qiaoning He, Man Zhao, Zhiwei Gong. Microbial Lipid Production from High Concentration of Volatile Fatty Acids via Trichosporon cutaneum for Biodiesel Preparation. Applied biochemistry and biotechnology. 2022 Jul; 194(7):2968-2979. doi: 10.1007/s12010-022-03903-x. [PMID: 35316474]
  • Wangxin Liu, Xianliang Luo, Tao Liu, Fengqin Feng. Study on the digestive characteristics of short-and medium-chain fatty acid structural lipid and its rapid intervention on gut microbes: In vivo and in vitro studies. Food chemistry. 2022 Jun; 380(?):131792. doi: 10.1016/j.foodchem.2021.131792. [PMID: 35086734]
  • Cassio Antônio Ficagna, Gabriela Miotto Galli, Emerson Zatti, Bruno Milhoreto Sponchiado, Bruno Giorgio de Oliveira Cecere, Guilherme L Deolindo, Lara Tarasconi, Vitor W Horn, Ricardo E Mendes, Bianca F Bissacotti, Maria Rosa Chitolina Schetinger, Marcel Manente Boiago, Aleksandro S da Silva. Butyric acid glycerides in the diet of broilers to replace conventional growth promoters: effects on performance, metabolism, and intestinal health. Archives of animal nutrition. 2022 Jun; 76(3-6):191-204. doi: 10.1080/1745039x.2022.2162796. [PMID: 36688467]
  • Haidan Shi, Junqi Yang, Jianke Li. Pomegranate peel polyphenols interaction with intestinal flora and its metabolic transformation. Xenobiotica; the fate of foreign compounds in biological systems. 2022 May; 52(5):442-452. doi: 10.1080/00498254.2022.2073291. [PMID: 35506342]
  • Kedan Cai, Yanhong Ma, Fanghao Cai, Xiaohan Huang, Liang Xiao, Chenyu Zhong, Pingping Ren, Qun Luo, Jianghua Chen, Fei Han. Changes of gut microbiota in diabetic nephropathy and its effect on the progression of kidney injury. Endocrine. 2022 05; 76(2):294-303. doi: 10.1007/s12020-022-03002-1. [PMID: 35246764]
  • Nadja Walle, Adrian A Doerr, Matthias W Laschke, Michael D Menger, Markus R Meyer, Peter H Schmidt, Nadine Schaefer. Systematic Studies on Temperature-Dependent In Vitro Stability during Storage and Smoking of the Synthetic Cannabinoid 5F-MDMB-P7AICA. Journal of analytical toxicology. 2022 Apr; 46(4):374-382. doi: 10.1093/jat/bkab022. [PMID: 33629711]
  • Longshan Qin, Weilei Yao, Tongxin Wang, Taimin Jin, Baoyin Guo, Shu Wen, Feiruo Huang. Targeting gut microbiota-derived butyrate improves hepatic gluconeogenesis through the cAMP-PKA-GCN5 pathway in late pregnant sows. Food & function. 2022 Apr; 13(8):4360-4374. doi: 10.1039/d2fo00094f. [PMID: 35355044]
  • Ming-Jun Chen, Yang Feng, Lu Gao, Ming-Xiong Lin, Shi-da Wang, Zhan-Qi Tong. Composite Sophora Colon-Soluble Capsule Ameliorates DSS-Induced Ulcerative Colitis in Mice via Gut Microbiota-Derived Butyric Acid and NCR+ ILC3. Chinese journal of integrative medicine. 2022 Apr; ?(?):. doi: 10.1007/s11655-022-3317-1. [PMID: 35412217]
  • Wei Li, Le Zhang, Qingbiao Xu, Wenbo Yang, Jianan Zhao, Ying Ren, Zhendong Yu, Libao Ma. Taxifolin Alleviates DSS-Induced Ulcerative Colitis by Acting on Gut Microbiome to Produce Butyric Acid. Nutrients. 2022 Mar; 14(5):. doi: 10.3390/nu14051069. [PMID: 35268045]
  • Lisanne M M Gommers, Jenny van der Wijst, Caro Bos, Luuk A M Janssen, René J M Bindels, Jeroen H F de Baaij, Joost G J Hoenderop. Colonic expression of calcium transporter TRPV6 is regulated by dietary sodium butyrate. Pflugers Archiv : European journal of physiology. 2022 03; 474(3):293-302. doi: 10.1007/s00424-021-02648-6. [PMID: 34997297]
  • Zhiyun Wang, Yan Lin, Lu Liu, Baodong Zheng, Yi Zhang, Hongliang Zeng. Effect of Lotus Seed Resistant Starch on Lactic Acid Conversion to Butyric Acid Fermented by Rat Fecal Microbiota. Journal of agricultural and food chemistry. 2022 Feb; 70(5):1525-1535. doi: 10.1021/acs.jafc.1c06000. [PMID: 34989559]
  • Zhumei Du, Yanli Lin, Lin Sun, Fuyu Yang, Yimin Cai. Microbial community structure, co-occurrence network and fermentation characteristics of woody plant silage. Journal of the science of food and agriculture. 2022 Feb; 102(3):1193-1204. doi: 10.1002/jsfa.11457. [PMID: 34343355]
  • Wenjing Yong, Yanhua Zhao, Xiao'e Jiang, Ping Li. Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production. Journal of applied microbiology. 2022 Feb; 132(2):1370-1383. doi: 10.1111/jam.15279. [PMID: 34470077]
  • Shushu Wang, Miaomiao Yuan, Linlin Zhang, Kecheng Zhu, Chunxiang Sheng, Feiye Zhou, Zhaoqian Xu, Qianqian Liu, Yun Liu, Jieli Lu, Xiao Wang, Libin Zhou. Sodium butyrate potentiates insulin secretion from rat islets at the expense of compromised expression of β cell identity genes. Cell death & disease. 2022 01; 13(1):67. doi: 10.1038/s41419-022-04517-1. [PMID: 35046383]
  • Yu-Jyun Huang, Pei-Ming Wang, Kuo-Shu Tang, Chih-Jen Chen, Ying-Hsien Huang, Mao-Meng Tiao. Butyrate ameliorates maternal high-fat diet-induced fetal liver cellular apoptosis. PloS one. 2022; 17(7):e0270657. doi: 10.1371/journal.pone.0270657. [PMID: 35793323]
  • Yuan Sun, Ling Cong, Song Yang, Rui Zhao, Zhuoling An, Lihong Liu. Moxifloxacin Induced Liver Injury by Causing Lachnospiraceae Deficiency and Interfering with Butyric Acid Production through Gut-Liver Axis. Disease markers. 2022; 2022(?):9302733. doi: 10.1155/2022/9302733. [PMID: 35531479]
  • Chenyang Li, Jiali Chen, Man Zhao, Mengqi Liu, Zhengkai Yue, Lei Liu, Fuchang Li. Effect of sodium butyrate on slaughter performance, serum indexes and intestinal barrier of rabbits. Journal of animal physiology and animal nutrition. 2022 Jan; 106(1):156-166. doi: 10.1111/jpn.13571. [PMID: 34096104]
  • Yutaka Hattori, Sayo Tsutsui, Chihiro Yamada, Yota Kobayashi, Tomoyuki Nakagawa, Masaya Shimada. Dietary Supplementation with Sodium Butyrate Reduces High-sucrose Diet-induced Hepatic Accumulation of Triacylglycerols and Expression of Fatty Acid Synthesis Enzymes in Rats. Journal of oleo science. 2022; 71(8):1189-1193. doi: 10.5650/jos.ess22112. [PMID: 35922931]
  • Qiu-Yun Li, Juan Chen, Yong-Heng Luo, Wei Zhang, En-Hua Xiao. Sodium Butyrate Pre-Treatment Enhance Differentiation of Bone Marrow Mesenchymal Stem Cells (BM-MSCs) into Hepatocytes and Improve Liver Injury. Current molecular medicine. 2022; 22(7):663-674. doi: 10.2174/1566524021666211014161716. [PMID: 34649486]
  • Tingting Zhou, Huiwen Xu, Xi Cheng, Yanqiu He, Qian Ren, Dongzhe Li, Yumei Xie, Chenlin Gao, Yuanyuan Zhang, Xiaodong Sun, Yong Xu, Wei Huang. Sodium Butyrate Attenuates Diabetic Kidney Disease Partially via Histone Butyrylation Modification. Mediators of inflammation. 2022; 2022(?):7643322. doi: 10.1155/2022/7643322. [PMID: 35909658]
  • N Zhang, B Qin. [Research progress of sodium butyrate in metabolic-associated fatty liver disease]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. 2021 Dec; 29(12):1229-1232. doi: 10.3760/cma.j.cn501113-20201113-00614. [PMID: 35045647]
  • Takio Inatomi, Mihoko Honma. Effects of probiotics on loperamide-induced constipation in rats. Scientific reports. 2021 12; 11(1):24098. doi: 10.1038/s41598-021-02931-7. [PMID: 34916548]
  • Jiaojiao Xu, Gaomiao Xie, Xinhua Li, Xin Wen, Zhen Cao, Baohua Ma, Yongde Zou, Na Zhang, Jiandui Mi, Yan Wang, Xindi Liao, Yinbao Wu. Sodium butyrate reduce ammonia and hydrogen sulfide emissions by regulating bacterial community balance in swine cecal content in vitro. Ecotoxicology and environmental safety. 2021 Dec; 226(?):112827. doi: 10.1016/j.ecoenv.2021.112827. [PMID: 34571416]
  • Rika Fukumori, Rina Ikeno, Kenichi Izumi, Kazuya Doi, Marina Otsuka, Kazuyuki Suzuki, Shin Oikawa. The effect of sodium butyrate supplementation on ruminal and fecal pH and serum lipopolysaccharide-binding protein after ruminal acidosis challenge in nonlactating cows. Animal science journal = Nihon chikusan Gakkaiho. 2021 Dec; 92(1):e13673. doi: 10.1111/asj.13673. [PMID: 34951079]
  • A Rouissi, A R Alfonso-Avila, F Guay, M Boulianne, M P Létourneau-Montminy. Effects of Bacillus subtilis, butyrate, mannan-oligosaccharide, and naked oat (ß-glucans) on growth performance, serum parameters, and gut health of broiler chickens. Poultry science. 2021 Dec; 100(12):101506. doi: 10.1016/j.psj.2021.101506. [PMID: 34731741]
  • Minh Tan Pham, Albert Jackson Yang, Ming-Shan Kao, Uuganbayar Gankhuyag, Enkhbat Zayabaatar, Shiow-Lian Catherine Jin, Chun-Ming Huang. Gut probiotic Lactobacillus rhamnosus attenuates PDE4B-mediated interleukin-6 induced by SARS-CoV-2 membrane glycoprotein. The Journal of nutritional biochemistry. 2021 12; 98(?):108821. doi: 10.1016/j.jnutbio.2021.108821. [PMID: 34271099]
  • Hui Chen, Gang Li, Jianqiang Zhang, Ting Zheng, Qianglin Chen, Yanxiang Zhang, Fei Yang, Chao Wang, Hao Nie, Bing Zheng, Quan Gong. Sodium butyrate ameliorates Schistosoma japonicum-induced liver fibrosis by inhibiting HMGB1 expression. Experimental parasitology. 2021 Dec; 231(?):108171. doi: 10.1016/j.exppara.2021.108171. [PMID: 34736899]
  • Veedamali S Subramanian, Trevor Teafatiller, Hamid Moradi, Jonathan S Marchant. Histone deacetylase inhibitors regulate vitamin C transporter functional expression in intestinal epithelial cells. The Journal of nutritional biochemistry. 2021 12; 98(?):108838. doi: 10.1016/j.jnutbio.2021.108838. [PMID: 34403723]
  • Mieke Steenbeke, Sophie Valkenburg, Tessa Gryp, Wim Van Biesen, Joris R Delanghe, Marijn M Speeckaert, Griet Glorieux. Gut Microbiota and Their Derived Metabolites, a Search for Potential Targets to Limit Accumulation of Protein-Bound Uremic Toxins in Chronic Kidney Disease. Toxins. 2021 11; 13(11):. doi: 10.3390/toxins13110809. [PMID: 34822593]
  • Geethika S G Liyanage, Ryo Inoue, Mina Fujitani, Tomoko Ishijima, Taisei Shibutani, Keiko Abe, Taro Kishida, Shinji Okada. Effects of Soy Isoflavones, Resistant Starch and Antibiotics on Polycystic Ovary Syndrome (PCOS)-Like Features in Letrozole-Treated Rats. Nutrients. 2021 Oct; 13(11):. doi: 10.3390/nu13113759. [PMID: 34836015]
  • Bin Yin, Hongyu Liu, Beiping Tan, Xiaohui Dong, Shuyan Chi, Qihui Yang, Shuang Zhang. Dietary supplementation of β-conglycinin, with or without sodium butyrate on the growth, immune response and intestinal health of hybrid grouper. Scientific reports. 2021 08; 11(1):17298. doi: 10.1038/s41598-021-96693-x. [PMID: 34453080]
  • Yu-Ping Hsiao, Hsiao-Ling Chen, Jen-Ning Tsai, Meei-Yn Lin, Jiunn-Wang Liao, Meng-Syuan Wei, Jiunn-Liang Ko, Chu-Chyn Ou. Administration of Lactobacillus reuteri Combined with Clostridium butyricum Attenuates Cisplatin-Induced Renal Damage by Gut Microbiota Reconstitution, Increasing Butyric Acid Production, and Suppressing Renal Inflammation. Nutrients. 2021 Aug; 13(8):. doi: 10.3390/nu13082792. [PMID: 34444952]
  • Ning Zhang, Yunfei Qu, Bo Qin. Sodium butyrate ameliorates non-alcoholic fatty liver disease by upregulating miR-150 to suppress CXCR4 expression. Clinical and experimental pharmacology & physiology. 2021 08; 48(8):1125-1136. doi: 10.1111/1440-1681.13497. [PMID: 33721354]