Racepinephrine (BioDeep_00000599958)

   

BioNovoGene_Lab2019


代谢物信息卡片


Alipogene tiparvovec

化学式: C9H13NO3 (183.0895)
中文名称: DL-肾上腺素(肾上腺素), 阿利泼金, 肾上腺素(盐酸盐), DL-肾上腺素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CNCC(C1=CC(=C(C=C1)O)O)O
InChI: InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3

描述信息

D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D009184 - Mydriatics
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents

同义名列表

4 个代谢物同义名

Alipogene tiparvovec; Racepinephrine; DL-Adrenalin; DL-Adrenaline



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 2 ALB, FOXP3
Peripheral membrane protein 1 LPL
Endoplasmic reticulum membrane 2 CD4, HTRA2
Mitochondrion membrane 1 HTRA2
Nucleus 3 ALB, FOXP3, HTRA2
cytosol 6 ALB, COMT, FOXP3, HTRA2, LIPA, MTTP
dendrite 1 COMT
mitochondrial membrane 1 HTRA2
centrosome 1 ALB
nucleoplasm 2 FOXP3, LIPA
Cell membrane 5 ADRB3, CD4, CD8A, COMT, LPL
lamellipodium 1 ANGPTL3
Multi-pass membrane protein 1 ADRB3
Synapse 1 COMT
cell surface 3 AMELX, ANGPTL3, LPL
Golgi apparatus 3 ALB, ANGPTL3, MTTP
Golgi membrane 1 INS
Lysosome 1 LIPA
plasma membrane 8 ADRB3, CD4, CD8A, COMT, CSF2, KLKB1, KNG1, LPL
Membrane 2 COMT, HTRA2
axon 1 COMT
basolateral plasma membrane 1 MTTP
extracellular exosome 6 ALB, APOC3, CETP, COMT, KLKB1, KNG1
endoplasmic reticulum 3 ALB, HTRA2, MTTP
extracellular space 10 ALB, ANGPTL3, APOC3, CETP, CRP, CSF2, INS, KLKB1, KNG1, LPL
lysosomal lumen 1 LIPA
mitochondrion 1 HTRA2
protein-containing complex 2 ALB, FOXP3
intracellular membrane-bounded organelle 3 COMT, CSF2, LIPA
Single-pass type I membrane protein 2 CD4, CD8A
Secreted 9 ALB, ANGPTL3, APOC3, CETP, CRP, CSF2, INS, KLKB1, LPL
extracellular region 12 ALB, AMELX, ANGPTL3, APOC3, CD8A, CETP, CRP, CSF2, INS, KLKB1, KNG1, LPL
cytoplasmic side of plasma membrane 1 HTRA2
Single-pass membrane protein 1 HTRA2
[Isoform 2]: Secreted 1 CD8A
Extracellular side 2 COMT, LPL
anchoring junction 1 ALB
CD40 receptor complex 1 HTRA2
external side of plasma membrane 2 CD4, CD8A
Secreted, extracellular space, extracellular matrix 2 AMELX, LPL
chylomicron 2 APOC3, LPL
high-density lipoprotein particle 1 CETP
very-low-density lipoprotein particle 2 APOC3, LPL
Early endosome 3 ANGPTL3, APOC3, CD4
Single-pass type II membrane protein 1 COMT
vesicle 2 CETP, MTTP
Cell projection, lamellipodium 1 ANGPTL3
Membrane raft 1 CD4
mitochondrial intermembrane space 1 HTRA2
collagen-containing extracellular matrix 4 AMELX, ANGPTL3, APOC3, KNG1
receptor complex 3 ADRB3, CD8A, MTTP
ciliary basal body 1 ALB
chromatin 2 FOXP3, HTRA2
cytoskeleton 1 HTRA2
centriole 1 ALB
[Isoform 1]: Endoplasmic reticulum 1 HTRA2
Secreted, extracellular space 1 KNG1
brush border membrane 1 MTTP
spindle pole 1 ALB
blood microparticle 2 ALB, KNG1
microvillus membrane 1 MTTP
fibrillar center 1 LIPA
endosome lumen 1 INS
plasma membrane raft 1 CD8A
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 6 ALB, AMELX, CD4, INS, KNG1, MTTP
platelet alpha granule lumen 2 ALB, KNG1
endocytic vesicle 1 AMELX
transport vesicle 1 INS
serine-type endopeptidase complex 1 HTRA2
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 CD4
[Isoform 1]: Cell membrane 1 CD8A
granulocyte macrophage colony-stimulating factor receptor complex 1 CSF2
spherical high-density lipoprotein particle 1 APOC3
T cell receptor complex 2 CD4, CD8A
intermediate-density lipoprotein particle 1 APOC3
catalytic complex 1 LPL
[Isoform Soluble]: Cytoplasm 1 COMT
[Isoform Membrane-bound]: Cell membrane 1 COMT
ciliary transition fiber 1 ALB


文献列表

  • Soyeon Park, Jihye You, Jaehyeon Lee, Esther Park. Two Case Reports of Life-Threatening Croup Caused by the SARS-CoV-2 Omicron BA.2 Variant in Pediatric Patients. Journal of Korean medical science. 2022 Jun; 37(24):e192. doi: 10.3346/jkms.2022.37.e192. [PMID: 35726145]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Xinfeng Zhao, Qian Li, Liujiao Bian, Xiaohui Zheng, Jianbin Zheng, Youyi Zhang, Zijian Li. Using immobilized G-protein coupled receptors to screen bioactive traditional Chinese medicine compounds with multiple targets. Journal of pharmaceutical and biomedical analysis. 2012 Nov; 70(?):549-52. doi: 10.1016/j.jpba.2012.05.004. [PMID: 22651959]
  • Xiaofang Zhang, Hong Zhao, Ying Xue, Zhijiao Wu, Yang Zhang, Yujian He, Xiangjun Li, Zhuobin Yuan. Colorimetric sensing of clenbuterol using gold nanoparticles in the presence of melamine. Biosensors & bioelectronics. 2012 Apr; 34(1):112-7. doi: 10.1016/j.bios.2012.01.026. [PMID: 22341861]
  • Li Liu, Jin-ao Duan, Yuping Tang, Jianming Guo, Nianyun Yang, Hongyue Ma, Xuqin Shi. Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation. Journal of ethnopharmacology. 2012 Jan; 139(2):381-7. doi: 10.1016/j.jep.2011.11.016. [PMID: 22123200]
  • Bao-Yu Huang, Yu-Cheng Chen, Guan-Ren Wang, Chuen-Ying Liu. Preparation and evaluation of a monolithic molecularly imprinted polymer for the chiral separation of neurotransmitters and their analogues by capillary electrochromatography. Journal of chromatography. A. 2011 Feb; 1218(6):849-55. doi: 10.1016/j.chroma.2010.12.054. [PMID: 21208621]
  • Emmanuel Guardiola, Bruno Chauffert, Delphine Delroeux, Bernard Royer, Bruno Heyd, Marielle Combe, Laurent Benoit, Sylvain Causeret, Martin Demarchi, Guy Magnin, Françoise Mayer, Hervé Tixier, Xavier Pivot. Intraoperative chemotherapy with cisplatin and epinephrine after cytoreductive surgery in patients with recurrent ovarian cancer: a phase I study. Anti-cancer drugs. 2010 Mar; 21(3):320-5. doi: 10.1097/cad.0b013e328334d953. [PMID: 20032778]
  • Palraj Kalimuthu, S Abraham John. Simultaneous determination of epinephrine, uric acid and xanthine in the presence of ascorbic acid using an ultrathin polymer film of 5-amino-1,3,4-thiadiazole-2-thiol modified electrode. Analytica chimica acta. 2009 Aug; 647(1):97-103. doi: 10.1016/j.aca.2009.05.036. [PMID: 19576392]
  • G F Orlando, K Langnaese, C Schulz, G Wolf, M Engelmann. Neuronal nitric oxide synthase gene inactivation reduces the expression of vasopressin in the hypothalamic paraventricular nucleus and of catecholamine biosynthetic enzymes in the adrenal gland of the mouse. Stress (Amsterdam, Netherlands). 2008 Jan; 11(1):42-51. doi: 10.1080/10253890701449867. [PMID: 17853069]
  • Anbu Pandian, Anjali Arora, Laurence S Sperling, Bobby V Khan. Targeting multiple dyslipidemias with fixed combinations--focus on extended release niacin and simvastatin. Vascular health and risk management. 2008; 4(5):1001-9. doi: 10.2147/vhrm.s3460. [PMID: 19183748]
  • T G Costello, J R Cormack, L E Mather, B LaFerlita, M A Murphy, K Harris. Plasma levobupivacaine concentrations following scalp block in patients undergoing awake craniotomy. British journal of anaesthesia. 2005 Jun; 94(6):848-51. doi: 10.1093/bja/aei135. [PMID: 15817709]
  • Jonathan V Hill, Malcolm E Forster. Cardiovascular responses of Chinook salmon (Oncorhynchus tshawytscha) during rapid anaesthetic induction and recovery. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2004 Feb; 137(2):167-77. doi: 10.1016/j.cca.2004.01.002. [PMID: 15050928]
  • Michael I Lindinger, Simon P Grudzien. Exercise-induced changes in plasma composition increase erythrocyte Na+,K+-ATPase, but not Na+-K+-2Cl- cotransporter, activity to stimulate net and unidirectional K+ transport in humans. The Journal of physiology. 2003 Dec; 553(Pt 3):987-97. doi: 10.1113/jphysiol.2003.052860. [PMID: 14528028]
  • Hong-ping Pan, Jia-zhen Yang, Lu-li Li, Fei Yi, Zhuo-qun Huang, Kai-wen Huang. [Experimental study of puerarin injection on the hemorheology in acute blood-stasis model rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2003 Dec; 28(12):1178-80. doi: NULL. [PMID: 15617506]
  • Heike Koelzow, Jacqueline A Gedney, Janos Baumann, Nicola J Snook, Mark C Bellamy. The effect of methylene blue on the hemodynamic changes during ischemia reperfusion injury in orthotopic liver transplantation. Anesthesia and analgesia. 2002 Apr; 94(4):824-9, table of contents. doi: 10.1097/00000539-200204000-00009. [PMID: 11916779]
  • K N Lapner, S F Perry. The role of angiotensin II in regulating catecholamine secretion during hypoxia in rainbow trout Oncorhynchus mykiss. The Journal of experimental biology. 2001 Dec; 204(Pt 23):4169-76. doi: 10.1242/jeb.204.23.4169. [PMID: 11809790]
  • T W Stief, M Weippert, V Kretschmer, H Renz. Arginine inhibits hemostasis activation. Thrombosis research. 2001 Nov; 104(4):265-74. doi: 10.1016/s0049-3848(01)00368-1. [PMID: 11728528]
  • T Dybvik, P Halvorsen, P A Steen. [Accidental administration of 50 mg racemic adrenaline to a 2-year-old boy]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. 1996 Mar; 116(7):834-6. doi: . [PMID: 8644093]
  • T Dybvik, P Halvorsen, P A Steen. Accidental intravenous administration of 50 mg of racemic adrenaline in a 2-year-old boy. European journal of anaesthesiology. 1995 Mar; 12(2):181-3. doi: . [PMID: 7781638]
  • D H Levine, A H Levkoff, L D Pappu, D M Purohit. Renal failure and other serious sequelae of epinephrine toxicity in neonates. Southern medical journal. 1985 Jul; 78(7):874-7. doi: 10.1097/00007611-198507000-00027. [PMID: 4012388]