Sakebiose (BioDeep_00000004702)

 

Secondary id: BioDeep_00000871997

human metabolite


代谢物信息卡片


(2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-{[(2S,3R,4S,5S,6R)-2,3,5-trihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}oxane-3,4,5-triol

化学式: C12H22O11 (342.1162)
中文名称: 尼日利亚糖
谱图信息: 最多检出来源 Homo sapiens(plant) 28.06%

分子结构信息

SMILES: C(C1C(C(C(C(O1)O)O)OC2C(C(C(C(O2)CO)O)O)O)O)O
InChI: InChI=1S/C12H22O11/c13-1-3-5(15)7(17)8(18)12(22-3)23-10-6(16)4(2-14)21-11(20)9(10)19/h3-20H,1-2H2/t3-,4-,5-,6+,7+,8+,9-,10+,11+,12-/m1/s1

描述信息

3-O-alpha-D-Mannopyranosyl-D-galactose is found in fruits. 3-O-alpha-D-Mannopyranosyl-D-galactose is isolated from enzymic hydrolysate of peach gum.
Isolated from enzymic hydrolysate of peach gum. 3-O-alpha-D-Mannopyranosyl-D-galactose is found in fruits.

同义名列表

13 个代谢物同义名

(2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-{[(2S,3R,4S,5S,6R)-2,3,5-trihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}oxane-3,4,5-triol; 3-O-alpha-D-Talopyranosyl-alpha-D-mannopyranoside; 3-O-alpha-D-Mannopyranosyl-D-galactose; 3-O-Α-D-mannopyranosyl-D-galactose; 3-O-a-D-Mannopyranosyl-D-galactose; 3-O-Talopyranosylmannopyranoside; Man(a1-3)a-Gal; Sakebiose; 3-O-TPMP; nigerose; Nigerose (Sakebiose); 3alpha-Mannobiose; Nigerose



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 MAPK8, SPTAN1, TYR
Peripheral membrane protein 1 GBA1
Endoplasmic reticulum membrane 5 B3GLCT, HMOX1, MLEC, MOGS, PMEL
Nucleus 3 GABPA, HMOX1, MAPK8
cytosol 4 GSR, HMOX1, MAPK8, SPTAN1
trans-Golgi network 1 GBA1
nucleoplasm 3 GABPA, HMOX1, MAPK8
Cell membrane 5 KIT, PTGDR2, SLC38A5, TNF, TREH
Cytoplasmic side 1 HMOX1
Multi-pass membrane protein 2 PTGDR2, SLC38A5
Synapse 1 MAPK8
cell cortex 1 SPTAN1
cell junction 1 SPTAN1
cell surface 1 TNF
Golgi apparatus 2 GBA1, PMEL
lysosomal membrane 2 GAA, GBA1
neuronal cell body 1 TNF
Lysosome 3 GAA, GBA1, TYR
acrosomal vesicle 1 KIT
plasma membrane 10 GAA, IFNLR1, KIT, MLEC, PMEL, PTGDR2, SLC38A5, SPTAN1, TNF, TREH
Membrane 10 GAA, HMOX1, IFNLR1, KIT, MLEC, MOGS, PMEL, SLC38A5, SPTAN1, TREH
axon 1 MAPK8
extracellular exosome 7 GAA, GBA1, GSR, MOGS, PMEL, SPTAN1, TREH
Lysosome membrane 2 GAA, GBA1
Lumenal side 1 GBA1
endoplasmic reticulum 5 GBA1, HMOX1, MLEC, MOGS, PMEL
extracellular space 5 HMOX1, IL10, IL2, KIT, TNF
lysosomal lumen 2 GAA, GBA1
perinuclear region of cytoplasm 2 HMOX1, TYR
mitochondrion 1 GSR
intracellular membrane-bounded organelle 3 GAA, SPTAN1, TYR
Single-pass type I membrane protein 5 IFNLR1, KIT, MLEC, PMEL, TYR
Secreted 4 GAA, IL10, IL2, PMEL
extracellular region 5 GAA, IL10, IL2, SPTAN1, TNF
cytoplasmic side of plasma membrane 1 KIT
mitochondrial outer membrane 1 HMOX1
mitochondrial matrix 1 GSR
external side of plasma membrane 3 GSR, KIT, TNF
Endosome, multivesicular body 1 PMEL
Extracellular vesicle 2 PMEL, SPTAN1
actin cytoskeleton 1 SPTAN1
microtubule cytoskeleton 1 SPTAN1
Melanosome membrane 2 PMEL, TYR
cell-cell junction 1 KIT
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 3 B3GLCT, MOGS, TNF
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 SPTAN1
receptor complex 1 KIT
neuron projection 1 PTGDR2
chromatin 1 GABPA
cell projection 1 SPTAN1
phagocytic cup 1 TNF
Cytoplasm, cell cortex 1 SPTAN1
Lipid-anchor, GPI-anchor 1 TREH
fibrillar center 1 KIT
specific granule membrane 1 MLEC
tertiary granule membrane 1 GAA
Melanosome 2 PMEL, TYR
side of membrane 1 TREH
[Isoform 3]: Cytoplasm 1 KIT
multivesicular body membrane 1 PMEL
cortical actin cytoskeleton 1 SPTAN1
specific granule lumen 1 SPTAN1
tertiary granule lumen 1 SPTAN1
azurophil granule membrane 1 GAA
Golgi apparatus, cis-Golgi network membrane 1 PMEL
Single-pass type IV membrane protein 1 HMOX1
spectrin 1 SPTAN1
ficolin-1-rich granule membrane 1 GAA
basal dendrite 1 MAPK8
cis-Golgi network membrane 1 PMEL
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
multivesicular body, internal vesicle 1 PMEL
oligosaccharyltransferase complex 1 MLEC
autolysosome lumen 1 GAA
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
organelle 1 SPTAN1


文献列表

  • Marc-Sebastian F Straka, Noha Abdullah Al-Otaibi, Philip D Whitfield, Mary K Doherty, Bruno F E Matarèse, Nigel K H Slater, Hassan Rahmoune. Disaccahrides-Based Cryo-Formulant Effect on Modulating Phospho/Mitochondrial Lipids and Biological Profiles of Human Leukaemia Cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2021 Apr; 55(2):206-221. doi: 10.33594/000000360. [PMID: 33914444]
  • Shangshang Sun, Xinlei Wei, Xigui Zhou, Chun You. Construction of an Artificial In Vitro Synthetic Enzymatic Platform for Upgrading Low-Cost Starch to Value-Added Disaccharides. Journal of agricultural and food chemistry. 2021 Jan; 69(1):302-314. doi: 10.1021/acs.jafc.0c06936. [PMID: 33371670]
  • Noha A S Al-Otaibi, Juliana S Cassoli, Daniel Martins-de-Souza, Nigel K H Slater, Hassan Rahmoune. Human leukemia cells (HL-60) proteomic and biological signatures underpinning cryo-damage are differentially modulated by novel cryo-additives. GigaScience. 2019 03; 8(3):. doi: 10.1093/gigascience/giy155. [PMID: 30535373]
  • Guangxi Zhou, Yang Song, Wenjing Yang, Yanmin Guo, Leilei Fang, Yamei Chen, Zhanju Liu. ASCA, ANCA, ALCA and Many More: Are They Useful in the Diagnosis of Inflammatory Bowel Disease?. Digestive diseases (Basel, Switzerland). 2016; 34(1-2):90-7. doi: 10.1159/000442934. [PMID: 26982193]
  • Elizabeth B Mearls, Daniel G Olson, Christopher D Herring, Lee R Lynd. Development of a regulatable plasmid-based gene expression system for Clostridium thermocellum. Applied microbiology and biotechnology. 2015 Sep; 99(18):7589-99. doi: 10.1007/s00253-015-6610-5. [PMID: 25994254]
  • Jinhu Wang, Qianqian Hou, Lihua Dong, Yongjun Liu, Chengbu Liu. QM/MM studies on the glycosylation mechanism of rice BGlu1 β-glucosidase. Journal of molecular graphics & modelling. 2011 Sep; 30(?):148-52. doi: 10.1016/j.jmgm.2011.06.012. [PMID: 21802967]
  • Jennifer L Meagher, Harry C Winter, Porscha Ezell, Irwin J Goldstein, Jeanne A Stuckey. Crystal structure of banana lectin reveals a novel second sugar binding site. Glycobiology. 2005 Oct; 15(10):1033-42. doi: 10.1093/glycob/cwi088. [PMID: 15944373]
  • Harry C Winter, Stefan Oscarson, Rikard Slättegård, Maozhong Tian, Irwin J Goldstein. Banana lectin is unique in its recognition of the reducing unit of 3-O-beta-glucosyl/mannosyl disaccharides: a calorimetric study. Glycobiology. 2005 Oct; 15(10):1043-50. doi: 10.1093/glycob/cwi074. [PMID: 15888634]
  • Maria Hrmova, Ross De Gori, Brian J Smith, Jon K Fairweather, Hugues Driguez, Joseph N Varghese, Geoffrey B Fincher. Structural basis for broad substrate specificity in higher plant beta-D-glucan glucohydrolases. The Plant cell. 2002 May; 14(5):1033-52. doi: 10.1105/tpc.010442. [PMID: 12034895]
  • I J Goldstein, H C Winter, H Mo, A Misaki, E J Van Damme, W J Peumans. Carbohydrate binding properties of banana (Musa acuminata) lectin II. Binding of laminaribiose oligosaccharides and beta-glucans containing beta1,6-glucosyl end groups. European journal of biochemistry. 2001 May; 268(9):2616-9. doi: 10.1046/j.1432-1327.2001.02149.x. [PMID: 11322881]
  • E E Swinny. A novel acetylated 3-deoxyanthocyanidin laminaribioside from the fern Blechnum novae-zelandiae. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2001 Mar; 56(3-4):177-80. doi: 10.1515/znc-2001-3-402. [PMID: 11371005]
  • E H Muslin, A M Kanikula, S E Clark, C A Henson. Overexpression, purification, and characterization of a barley alpha-glucosidase secreted by Pichia pastoris. Protein expression and purification. 2000 Feb; 18(1):20-6. doi: 10.1006/prep.1999.1160. [PMID: 10648165]
  • J N Freund, F Gossé, F Raul. Derivatives of plant beta-glucans are hydrolyzed by intestinal lactase-phlorizin hydrolase of mammals. Enzyme. 1991; 45(1-2):71-4. doi: 10.1159/000468868. [PMID: 1806369]
  • D H HUTSON, D J MANNERS. STUDIES ON CARBOHYDRATE-METABOLIZING ENZYMES. THE HYDROLYSIS OF ALPHA-GLUCOSIDES, INCLUDING NIGEROSE, BY EXTRACTS OF ALFALFA AND OTHER HIGHER PLANTS. The Biochemical journal. 1965 Mar; 94(?):783-9. doi: 10.1042/bj0940783. [PMID: 14340072]
  • . . . . doi: . [PMID: 12637023]