Acetylphenol (BioDeep_00000004445)

Main id: BioDeep_00000014757

 

PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


Acetic acid,phenyl ester

化学式: C8H8O2 (136.0524)
中文名称: 乙酸苯酯, 苯乙酸酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)OC1=CC=CC=C1
InChI: InChI=1S/C8H8O2/c1-7(9)10-8-5-3-2-4-6-8/h2-6H,1H3

描述信息

C274 - Antineoplastic Agent > C2122 - Cell Differentiating Agent > C1934 - Differentiation Inducer
Phenyl acetate is an endogenous metabolite.

同义名列表

5 个代谢物同义名

Acetic acid,phenyl ester; PHENYL ACETATE; Acetylphenol; Phenyl acetate; Phenyl acetate



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(3)

BioCyc(0)

PlantCyc(0)

代谢反应

66 个相关的代谢反应过程信息。

Reactome(66)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ADA, CALR, FH, PPY, TXN, TXNIP, TYR
Peripheral membrane protein 2 ACHE, ADA
Endoplasmic reticulum membrane 2 CALR, PON1
Nucleus 4 ACHE, CALR, FH, TXN
cytosol 6 ADA, CALR, FH, LIPE, TXN, TXNIP
nucleoplasm 2 RRS1, TXN
Cell membrane 5 ACHE, ADA, LIPE, SLC38A5, TNF
Multi-pass membrane protein 1 SLC38A5
Synapse 1 ACHE
cell junction 1 ADA
cell surface 4 ACHE, ADA, CALR, TNF
glutamatergic synapse 1 CALR
Golgi apparatus 2 ACHE, ATRN
Golgi membrane 1 INS
lysosomal membrane 1 GAA
neuromuscular junction 1 ACHE
neuronal cell body 1 TNF
postsynapse 1 CALR
smooth endoplasmic reticulum 1 CALR
Cytoplasm, cytosol 2 CALR, LIPE
Lysosome 4 ADA, GAA, SGSH, TYR
acrosomal vesicle 1 CALR
plasma membrane 7 ACHE, ADA, ATRN, BCHE, GAA, SLC38A5, TNF
Membrane 6 ACHE, ADA, CALR, GAA, LIPE, SLC38A5
caveola 1 LIPE
extracellular exosome 7 ATRN, CALR, FH, GAA, PON1, SGSH, TXN
Lysosome membrane 1 GAA
endoplasmic reticulum 2 CALR, RRS1
extracellular space 9 ACHE, ATRN, BCHE, CALR, CRP, INS, PON1, PPY, TNF
lysosomal lumen 2 GAA, SGSH
perinuclear region of cytoplasm 3 ACHE, CALR, TYR
mitochondrion 1 FH
intracellular membrane-bounded organelle 2 GAA, TYR
Single-pass type I membrane protein 2 ATRN, TYR
Secreted 7 ACHE, BCHE, CRP, GAA, INS, PPY, TXN
extracellular region 11 ACHE, BCHE, CALR, CRP, GAA, INS, PLA2G7, PON1, PPY, TNF, TXN
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 1 FH
Extracellular side 2 ACHE, ADA
Cytoplasmic vesicle lumen 1 ADA
anchoring junction 1 ADA
external side of plasma membrane 3 ADA, CALR, TNF
Secreted, extracellular space, extracellular matrix 1 CALR
high-density lipoprotein particle 2 PLA2G7, PON1
low-density lipoprotein particle 1 PLA2G7
nucleolus 1 RRS1
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
focal adhesion 1 CALR
basement membrane 1 ACHE
collagen-containing extracellular matrix 1 CALR
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 CALR
Chromosome 1 FH
Secreted, extracellular space 1 PLA2G7
blood microparticle 2 BCHE, PON1
Lipid-anchor, GPI-anchor 1 ACHE
site of double-strand break 1 FH
[Isoform 3]: Secreted 1 ATRN
nuclear envelope 1 CALR
endosome lumen 1 INS
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
tertiary granule membrane 1 GAA
Melanosome 1 TYR
side of membrane 1 ACHE
secretory granule lumen 1 INS
endoplasmic reticulum quality control compartment 1 CALR
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 BCHE, CALR, INS
transport vesicle 1 INS
azurophil granule membrane 1 GAA
preribosome, large subunit precursor 1 RRS1
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 CALR, INS
nuclear envelope lumen 1 BCHE
condensed nuclear chromosome 1 RRS1
Sarcoplasmic reticulum lumen 1 CALR
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
lumenal side of endoplasmic reticulum membrane 1 CALR
MHC class I peptide loading complex 1 CALR
[Isoform 1]: Cell membrane 1 ATRN
spherical high-density lipoprotein particle 1 PON1
endocytic vesicle lumen 1 CALR
ribosome 1 CALR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
Cytoplasmic vesicle, secretory vesicle, Cortical granule 1 CALR
cortical granule 1 CALR
[Isoform Mitochondrial]: Mitochondrion 1 FH
[Isoform Cytoplasmic]: Cytoplasm, cytosol 1 FH
Cytolytic granule 1 CALR
autolysosome lumen 1 GAA
[Isoform H]: Cell membrane 1 ACHE
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Md Ariful Islam, Sania Ashrafi, Khondaker Miraz Rahman, Shamim Ahmed, A H M Shofiul Islam Molla Jamal, Monira Ahsan. Isolation and Characterization of One New Natural Compound with Other Potential Bioactive Secondary Metabolites from Glycosmis cyanocarpa (Blume) Spreng. (Family: Rutaceae). Molecules (Basel, Switzerland). 2023 Feb; 28(5):. doi: 10.3390/molecules28052207. [PMID: 36903452]
  • R Todd Stravitz, Michelle Gottfried, Valerie Durkalski, Robert J Fontana, A James Hanje, David Koch, Bilal Hameed, Daniel Ganger, Ram M Subramanian, Stan Bukofzer, William R Ravis, Kristen Clasen, Averell Sherker, Lanna Little, William M Lee. Safety, tolerability, and pharmacokinetics of l-ornithine phenylacetate in patients with acute liver injury/failure and hyperammonemia. Hepatology (Baltimore, Md.). 2018 03; 67(3):1003-1013. doi: 10.1002/hep.29621. [PMID: 29080224]
  • Anna Bizoń, Halina Milnerowicz. The effect of divalent metal chelators and cadmium on serum phosphotriesterase, lactonase and arylesterase activities of paraoxonase 1. Environmental toxicology and pharmacology. 2018 Mar; 58(?):77-83. doi: 10.1016/j.etap.2017.12.019. [PMID: 29306821]
  • Anna Wysocka, Marek Cybulski, Henryk Berbeć, Andrzej Wysokiński, Janusz Stążka, Jadwiga Daniluk, Tomasz Zapolski. Dynamic changes of paraoxonase 1 activity towards paroxon and phenyl acetate during coronary artery surgery. BMC cardiovascular disorders. 2017 04; 17(1):92. doi: 10.1186/s12872-017-0528-z. [PMID: 28376720]
  • Marta Rusek, Jolanta Elżbieta Pastryk, Jerzy Bełtowski. Modulation of paraoxonase 1 (PON1) activity and protein N-homocysteinylation by bisphosphonates in rats. Chemico-biological interactions. 2016 Nov; 259(Pt B):401-406. doi: 10.1016/j.cbi.2016.07.002. [PMID: 27387541]
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  • Jina Kim, Victor Sukbong Hong, Jinho Lee. Antioxidant activity of 3,4,5-trihydroxyphenylacetamide derivatives. Archives of pharmacal research. 2014 Mar; 37(3):324-31. doi: 10.1007/s12272-013-0189-0. [PMID: 23812775]
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  • Mohammed Salman, Chandramouli Malleda, Narayanavari A Suneel, Insaf A Qureshi, Elizabeth A Frank, Cletus Jm D'Souza. Homology modeling of human serum paraoxonase1 and its molecular interaction studies with aspirin and cefazolin. Bioinformation. 2011; 7(2):59-63. doi: 10.6026/97320630007059. [PMID: 21938206]
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  • Asma Ezzaher, Dhouha Haj Mouhamed, Anwar Mechri, Manel Araoud, Fadoua Neffati, Wahiba Douki, Lotfi Gaha, Mohamed Fadhel Najjar. Lower paraoxonase 1 activity in Tunisian bipolar I patients. Annals of general psychiatry. 2010 Oct; 9(?):36. doi: 10.1186/1744-859x-9-36. [PMID: 20964824]
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  • Kimberly A Davis, J Allen Crow, Howard W Chambers, Edward C Meek, Janice E Chambers. Racial differences in paraoxonase-1 (PON1): a factor in the health of southerners?. Environmental health perspectives. 2009 Aug; 117(8):1226-31. doi: 10.1289/ehp.0900569. [PMID: 19672401]
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