Laevuflex (BioDeep_00000004155)

 

Secondary id: BioDeep_00000410649

PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


L-Sorbose

化学式: C6H12O6 (180.0634)
中文名称: L-(-)-山梨糖
谱图信息: 最多检出来源 Macaca mulatta(otcml) 13.17%

分子结构信息

SMILES: C1C(C(C(C(O1)(CO)O)O)O)O
InChI: InChI=1S/C6H12O6/c7-2-6(11)5(10)4(9)3(8)1-12-6/h3-5,7-11H,1-2H2

描述信息

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite.
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite.

同义名列表

5 个代谢物同义名

L-Sorbose; Laevuflex; (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one; L-Sorbose; L-(-)-Sorbose



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(3)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ANG, CAT, HPGDS, KHK, MED28, MSMP, PLA2G12A, VDR
Peripheral membrane protein 3 HSD17B6, MED28, SORD
Mitochondrion membrane 1 SORD
Nucleus 4 ANG, KDR, MED28, VDR
cytosol 7 ANG, CAT, GALE, HPGDS, KHK, SORD, VDR
mitochondrial membrane 1 SORD
nucleoplasm 3 HPGDS, MED28, VDR
RNA polymerase II transcription regulator complex 1 VDR
Cell membrane 4 KDR, SLC2A5, TRPV5, TRPV6
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 4 KCNJ3, SLC2A5, TRPV5, TRPV6
cell junction 1 KDR
cell surface 1 EPO
Golgi apparatus 1 KDR
Golgi membrane 1 INS
growth cone 1 ANG
lysosomal membrane 1 GAA
neuronal cell body 1 ANG
presynaptic membrane 1 KCNJ3
sarcolemma 1 SLC2A5
Lysosome 1 GAA
endosome 1 KDR
plasma membrane 6 GAA, KCNJ3, KDR, SLC2A5, TRPV5, TRPV6
Membrane 7 CAT, GAA, KCNJ3, MED28, SORD, TRPV5, TRPV6
apical plasma membrane 2 SLC2A5, TRPV5
extracellular exosome 6 CAT, EPO, GAA, KHK, SLC2A5, SORD
Lysosome membrane 1 GAA
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 HSD17B6, KDR
extracellular space 6 ANG, EPO, IGF1, INS, MSMP, SORD
lysosomal lumen 1 GAA
mitochondrion 1 CAT
protein-containing complex 1 CAT
intracellular membrane-bounded organelle 4 CAT, GAA, HPGDS, HSD17B6
Microsome membrane 1 HSD17B6
Secreted 7 ANG, EPO, GAA, IGF1, INS, MSMP, PLA2G12A
extracellular region 8 ANG, CAT, EPO, GAA, IGF1, INS, KDR, PLA2G12A
[Isoform 2]: Secreted 1 KDR
mitochondrial matrix 1 CAT
anchoring junction 1 KDR
motile cilium 1 SORD
external side of plasma membrane 2 KCNJ3, KDR
actin cytoskeleton 1 ANG
T-tubule 1 KCNJ3
nucleolus 1 ANG
Early endosome 1 KDR
Apical cell membrane 2 SLC2A5, TRPV5
Cell membrane, sarcolemma 1 SLC2A5
Membrane raft 1 KDR
focal adhesion 1 CAT
Peroxisome 1 CAT
basement membrane 1 ANG
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
receptor complex 2 KDR, VDR
chromatin 1 VDR
core mediator complex 1 MED28
mediator complex 1 MED28
Chromosome 1 ANG
Nucleus, nucleolus 1 ANG
Cell projection, cilium, flagellum 1 SORD
endosome lumen 1 INS
sorting endosome 1 KDR
monoatomic ion channel complex 1 KCNJ3
specific granule membrane 1 SLC2A5
tertiary granule membrane 1 GAA
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 1 ANG
cell body 1 EPO
voltage-gated potassium channel complex 1 KCNJ3
exocytic vesicle 1 IGF1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 CAT, EPO, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
cortical actin cytoskeleton 1 MED28
platelet alpha granule lumen 1 IGF1
endocytic vesicle 1 ANG
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
parallel fiber to Purkinje cell synapse 1 KCNJ3
calcium channel complex 1 TRPV6
ficolin-1-rich granule membrane 1 GAA
angiogenin-PRI complex 1 ANG
catalase complex 1 CAT
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
autolysosome lumen 1 GAA
I(KACh) inward rectifier potassium channel complex 1 KCNJ3


文献列表

  • Yasuo Nagata, Narumi Mizuta, Akane Kanasaki, Kazunari Tanaka. Rare sugars, d-allulose, d-tagatose and d-sorbose, differently modulate lipid metabolism in rats. Journal of the science of food and agriculture. 2018 Mar; 98(5):2020-2026. doi: 10.1002/jsfa.8687. [PMID: 28940418]
  • Tadashi Sato, Shiro Kusuhara, Wakae Yokoi, Masahiko Ito, Kouji Miyazaki. Prebiotic potential of L-sorbose and xylitol in promoting the growth and metabolic activity of specific butyrate-producing bacteria in human fecal culture. FEMS microbiology ecology. 2017 01; 93(1):. doi: 10.1093/femsec/fiw227. [PMID: 27810878]
  • M T Ortega, B Jeffery, J E Riviere, N A Monteiro-Riviere. Toxicological effects of pet food ingredients on canine bone marrow-derived mesenchymal stem cells and enterocyte-like cells. Journal of applied toxicology : JAT. 2016 Feb; 36(2):189-98. doi: 10.1002/jat.3158. [PMID: 25976427]
  • J Koči, B Jeffery, J E Riviere, N A Monteiro-Riviere. In vitro safety assessment of food ingredients in canine renal proximal tubule cells. Toxicology in vitro : an international journal published in association with BIBRA. 2015 Mar; 29(2):289-98. doi: 10.1016/j.tiv.2014.11.002. [PMID: 25458622]
  • Takako Yamada, Noriko Hayashi, Tetsuo Iida, Satoshi Takamine, Kazuhiro Okuma, Tatsuhiro Matsuo. Dietary D-sorbose decreases serum insulin levels in growing Sprague-Dawley rats. Journal of nutritional science and vitaminology. 2014; 60(4):297-9. doi: 10.3177/jnsv.60.297. [PMID: 25297620]
  • Yun Gao, Ying-Jin Yuan. Comprehensive quality evaluation of corn steep liquor in 2-keto-L-gulonic acid fermentation. Journal of agricultural and food chemistry. 2011 Sep; 59(18):9845-53. doi: 10.1021/jf201792u. [PMID: 21793578]
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  • Akihito Kano, Kenji Gomi, Yumiko Yamasaki-Kokudo, Masaru Satoh, Takeshi Fukumoto, Kouhei Ohtani, Shigeyuki Tajima, Ken Izumori, Keiji Tanaka, Yutaka Ishida, Yasuomi Tada, Yoko Nishizawa, Kazuya Akimitsu. A rare sugar, d-allose, confers resistance to rice bacterial blight with upregulation of defense-related genes in Oryza sativa. Phytopathology. 2010 Jan; 100(1):85-90. doi: 10.1094/phyto-100-1-0085. [PMID: 19968553]
  • Anselm Lehmacher, Jochen Bockemühl. L-Sorbose utilization by virulent Escherichia coli and Shigella: different metabolic adaptation of pathotypes. International journal of medical microbiology : IJMM. 2007 Jul; 297(4):245-54. doi: 10.1016/j.ijmm.2007.01.007. [PMID: 17382590]
  • A Xu, J Yao, L Yu, S Lv, J Wang, B Yan, Z Yu. Mutation of Gluconobacter oxydans and Bacillus megaterium in a two-step process of l-ascorbic acid manufacture by ion beam. Journal of applied microbiology. 2004; 96(6):1317-23. doi: 10.1111/j.1365-2672.2004.02270.x. [PMID: 15139924]
  • Yoshimitsu Takakura, Shigeru Kuwata. Purification, characterization, and molecular cloning of a pyranose oxidase from the fruit body of the basidiomycete, Tricholoma matsutake. Bioscience, biotechnology, and biochemistry. 2003 Dec; 67(12):2598-607. doi: 10.1271/bbb.67.2598. [PMID: 14730138]
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