Capsorubin (BioDeep_00000004108)

 

Secondary id: BioDeep_00000638799

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


(2E,4E,6E,8E,10E,12E,14E,16E,18E)-1,20-bis[(1R,4S)-4-hydroxy-1,2,2-trimethylcyclopentyl]-4,8,13,17-tetramethylicosa-2,4,6,8,10,12,14,16,18-nonaene-1,20-dione

化学式: C40H56O4 (600.4178)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 19.78%

分子结构信息

SMILES: C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C(=O)[C@]1(C)C[C@H](CC1(C)C)O)/C=C/C=C(\C)/C=C/C(=O)[C@]1(C)C[C@H](CC1(C)C)O
InChI: InChI=1S/C40H56O4/c1-29(17-13-19-31(3)21-23-35(43)39(9)27-33(41)25-37(39,5)6)15-11-12-16-30(2)18-14-20-32(4)22-24-36(44)40(10)28-34(42)26-38(40,7)8/h11-24,33-34,41-42H,25-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t33-,34-,39-,40-/m0/s1

描述信息

Capsorubin is found in herbs and spices. Capsorubin is a constituent of paprika (Capsicum annuum). Potential nutriceutical.Capsorubin is one of the main colouring constituant of paprika oleoresin (paprika extract). (Wikipedia).
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
Constituent of paprika (Capsicum annuum). Potential nutriceutical

同义名列表

9 个代谢物同义名

(2E,4E,6E,8E,10E,12E,14E,16E,18E)-1,20-bis[(1R,4S)-4-hydroxy-1,2,2-trimethylcyclopentyl]-4,8,13,17-tetramethylicosa-2,4,6,8,10,12,14,16,18-nonaene-1,20-dione; 1,20-bis(4-hydroxy-1,2,2-trimethylcyclopentyl)-4,8,13,17-tetramethylicosa-2,4,6,8,10,12,14,16,18-nonaene-1,20-dione; (3S,5R,3S,5R)-3,3-Dihydroxy-kappa,kappa-carotene-6,6-dione; 3,3-Dihyroxy-kappa,kappa-carotene-6,6-dione; 3,3-Dihydroxy-K,K-carotene-6,6-dione; all-trans-Capsorubin; e160 (Capsorubin); Capsorubin; Capsorubin



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

4 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(3)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

28 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ABCB1, CASP3, CAT, GGPS1, HBS1L, KRT7
Peripheral membrane protein 1 MBP
Nucleus 3 CASP3, KRT7, MBP
cytosol 6 CASP3, CAT, GGPS1, HBS1L, KRT7, MBP
nucleoplasm 2 CASP3, GGPS1
Cell membrane 2 ABCB1, TNF
Cytoplasmic side 1 MBP
Multi-pass membrane protein 1 ABCB1
Synapse 1 MBP
cell surface 4 ABCB1, ADIPOQ, MBP, TNF
glutamatergic synapse 1 CASP3
Golgi membrane 1 INS
neuronal cell body 3 CASP3, MBP, TNF
plasma membrane 4 ABCB1, F2, MBP, TNF
Membrane 3 ABCB1, CAT, HBS1L
apical plasma membrane 1 ABCB1
extracellular exosome 7 ABCB1, CAT, F2, HBS1L, KRT7, MBP, RETN
endoplasmic reticulum 1 ADIPOQ
extracellular space 6 ADIPOQ, F2, IL6, INS, RETN, TNF
perinuclear region of cytoplasm 1 GGPS1
mitochondrion 1 CAT
protein-containing complex 2 CAT, MBP
intracellular membrane-bounded organelle 1 CAT
postsynaptic density 1 CASP3
Secreted 5 ADIPOQ, F2, IL6, INS, RETN
extracellular region 8 ADIPOQ, CAT, F2, IL6, INS, MBP, RETN, TNF
mitochondrial matrix 1 CAT
external side of plasma membrane 1 TNF
Z disc 1 GGPS1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 ABCB1
Cytoplasm, perinuclear region 1 GGPS1
Membrane raft 1 TNF
focal adhesion 1 CAT
Peroxisome 1 CAT
collagen trimer 1 ADIPOQ
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 3 ADIPOQ, F2, MBP
intermediate filament 1 KRT7
phagocytic cup 1 TNF
cell periphery 1 MBP
[Isoform 3]: Nucleus 1 MBP
blood microparticle 1 F2
endosome lumen 1 INS
myelin sheath 1 MBP
intermediate filament cytoskeleton 1 KRT7
Cytoplasm, myofibril, sarcomere, Z line 1 GGPS1
ficolin-1-rich granule lumen 2 CAT, MBP
secretory granule lumen 2 CAT, INS
Golgi lumen 2 F2, INS
endoplasmic reticulum lumen 3 F2, IL6, INS
specific granule lumen 1 RETN
transport vesicle 2 INS, MBP
azurophil granule lumen 1 RETN
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
[Isoform 2]: Cytoplasm 1 HBS1L
external side of apical plasma membrane 1 ABCB1
death-inducing signaling complex 1 CASP3
keratin filament 1 KRT7
cytosolic ribosome 1 HBS1L
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
compact myelin 1 MBP
internode region of axon 1 MBP
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
[Bone marrow proteoglycan]: Secreted 1 MBP
Myelin membrane 1 MBP
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
Dom34-Hbs1 complex 1 HBS1L


文献列表

  • Daojiu Zhang, Shaoyu Wang, Mingchun Wang, Zijian Wu, Steve W Cui, Hao Wang, Biao Wang. Stability and bioaccessibility improvement of capsorubin using bovine serum albumin-dextran-gallic acid and sodium alginate. International journal of biological macromolecules. 2021 Jul; 182(?):1362-1370. doi: 10.1016/j.ijbiomac.2021.05.033. [PMID: 33965493]
  • Maiko Furubayashi, Akiko Kubo, Miho Takemura, Yuko Otani, Takashi Maoka, Yoshinobu Terada, Katsuro Yaoi, Kohji Ohdan, Norihiko Misawa, Yasuo Mitani. Capsanthin Production in Escherichia coli by Overexpression of Capsanthin/Capsorubin Synthase from Capsicum annuum. Journal of agricultural and food chemistry. 2021 May; 69(17):5076-5085. doi: 10.1021/acs.jafc.1c00083. [PMID: 33890772]
  • Muhammad Asim Siddique, Jonas Grossmann, Wilhelm Gruissem, Sacha Baginsky. Proteome analysis of bell pepper (Capsicum annuum L.) chromoplasts. Plant & cell physiology. 2006 Dec; 47(12):1663-73. doi: 10.1093/pcp/pcl033. [PMID: 17098784]
  • Antonio Pérez-Gálvez, Hans D Martin, Helmut Sies, Wilhelm Stahl. Incorporation of carotenoids from paprika oleoresin into human chylomicrons. The British journal of nutrition. 2003 Jun; 89(6):787-93. doi: 10.1079/bjn2003842. [PMID: 12828795]
  • A Pérez-Gálvez, M I Mínguez-Mosquera. Structure-reactivity relationship in the oxidation of carotenoid pigments of the pepper (Capsicum annuum L.). Journal of agricultural and food chemistry. 2001 Oct; 49(10):4864-9. doi: 10.1021/jf010547c. [PMID: 11600036]
  • M Weissenberg, I Schaeffler, E Menagem, M Barzilai, A Levy. Isocratic non-aqueous reversed-phase high-performance liquid chromatographic separation of capsanthin and capsorubin in red peppers (Capsicum annuum L.), paprika and oleoresin. Journal of chromatography. A. 1997 Jan; 757(1-2):89-95. doi: 10.1016/s0021-9673(96)00665-6. [PMID: 9025261]
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