CE(18:1(9Z)) (BioDeep_00000004106)

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019 Volatile Flavor Compounds

代谢物信息卡片

[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (Z)-octadec-9-enoate

化学式: C45H78O2 (650.6001487999999)
中文名称: 胆甾醇油酸酯, 胆固醇油酸酯
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 8.33%

分子结构信息

SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
InChI: InChI=1S/C45H78O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25-43(46)47-38-30-32-44(5)37(34-38)26-27-39-41-29-28-40(36(4)24-22-23-35(2)3)45(41,6)33-31-42(39)44/h14-15,26,35-36,38-42H,7-13,16-25,27-34H2,1-6H3/t36-,38+,39+,40-,41+,42+,44+,45-/m1/s1

描述信息

Cholesteryl oleate is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a combination steroid and alcohol) and a lipid found in the cell membranes of all body tissues, and transported in the blood plasma of all animals. The accumulation of cholesterol esters in the arterial intima (the innermost layer of an artery, in direct contact with the flowing blood) is a characteristic feature of atherosclerosis. Atherosclerosis is a disease affecting arterial blood vessels. It is a chronic inflammatory response in the walls of arteries, in large part to the deposition of lipoproteins (plasma proteins that carry cholesterol and triglycerides). Cholesteryl esters, formed by the esterification of cholesterol with long-chain fatty acids, on one hand, are the means by which cholesterol is transported through the blood by lipoproteins, on the other, the way cholesterol itself can be accumulated in the cells. (PMID: 15939411) [HMDB]
Cholesteryl oleate is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a combination steroid and alcohol) and a lipid found in the cell membranes of all body tissues, and transported in the blood plasma of all animals. The accumulation of cholesterol esters in the arterial intima (the innermost layer of an artery, in direct contact with the flowing blood) is a characteristic feature of atherosclerosis. Atherosclerosis is a disease affecting arterial blood vessels. It is a chronic inflammatory response in the walls of arteries, in large part to the deposition of lipoproteins (plasma proteins that carry cholesterol and triglycerides). Cholesteryl esters, formed by the esterification of cholesterol with long-chain fatty acids, on one hand, are the means by which cholesterol is transported through the blood by lipoproteins, on the other, the way cholesterol itself can be accumulated in the cells. (PMID: 15939411).
Cholesteryl oleate is an esterified form of Cholesterol. Cholesteryl oleate can be used in the generation of solid lipid nanoparticle (SLN, a nanoparticle-based method for gene therapy)[1][2].

同义名列表

53 个代谢物同义名

[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (Z)-octadec-9-enoate; [10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] octadec-9-enoate; (2R,5S,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-yl (9Z)-octadec-9-enoate; Cholest-5-en-3-ol (3b)-(Z)-9-octadecenoic acid; Cholest-5-en-3-ol (3b)-(Z)-9-octadecenoate; cholest-5-en-3b-yl (9Z-octadecenoate); 3β-Hydroxy-5-cholestene 3-oleate; Cholesteryl 1-(9Z-octadecenoic acid); Cholesterol 1-(9Z-octadecenoic acid); Cholesteryl-β-δ-glucoside; Cholesterol 1-(9Z-octadecenoic acid; Cholesteryl cis-9-octadecenoic acid; 3beta-Hydroxy-5-cholestene 3-oleate; Cholesterol 1-(9Z-octadecenoate); Cholesteryl-beta-delta-glucoside; Cholesteryl 1-(9Z-octadecenoate); Cholest-5-en-3-β-yl oleate; 1-(9Z-Octadecenoyl)-cholesterol; Cholesterol 1-(9Z-octadecenoate; Cholesteryl cis-9-octadecenoate; Cholesteryl-β-D-glucoside; Cholesterol ester(18:1n9/0:0); Cholesterol ester(18:1W9/0:0); Cholest-5-en-3-beta-yl oleate; Oleic acid cholesteryl ester; Cholesteryl-beta-D-glucoside; Cholesterol ester(18:1/0:0); Cholesteryl [9,10-3H]oleate; 18:1(9Z) Cholesterol ester; Cholesterol 3β-oleate; Cholesteryl oleate-9,10-3H; 5-Cholesten-3b-ol 3-oleate; Cholesteryl oleate-9,10-t2; Cholesterol 1-oleoic acid; Cholesteryl 1-oleoic acid; Cholesterol 3beta-oleate; Cholesteryl oleic ester; Cholesterol ester(18:1); 18:1 Cholesterol ester; Cholesteryl 1-oleoate; Cholesterol 1-oleoate; 1-Oleoyl-cholesterol; Cholesteroyl-oleate; Cholest-5-en-3b-yl; Cholesteryl oleate; Oleoylcholesterol; CE(18:1W9/0:0); CE(18:1n9/0:0); CE(18:1(9Z)); CE(18:1/0:0); CE(18:1); CE 18:1; Cholesteryl oleate

数据库引用编号

20 个数据库交叉引用编号

ChEBI: CHEBI:46898
KEGG: C14641
PubChem: 50938266
PubChem: 5283632
PubChem: 78971
HMDB: HMDB0000918
Metlin: METLIN3907
ChEMBL: CHEMBL1097567
LipidMAPS: LMST01020003
foodb: FDB022317
chemspider: 26263151
CAS: 303-43-5
PMhub: MS000015708
PubChem: 17395641
PDB-CCD: 2OB
NIKKAJI: J193.711A
RefMet: CE 18:1
medchemexpress: HY-113217
BioNovoGene_Lab2019: BioNovoGene_Lab2019-577
KNApSAcK: 46898

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Doerte Luensmann, Negar Babaei Omali, Adeline Suko, Elizabeth Drolle, Miriam Heynen, Lakshman N Subbaraman, Charley Scales, Zohra Fadli, Lyndon Jones. Kinetic Deposition of Polar and Non-polar Lipids on Silicone Hydrogel Contact Lenses. Current eye research. 2020 12; 45(12):1477-1483. doi: 10.1080/02713683.2020.1755696. [PMID: 32281422]
Menno Hoekstra, Ronald J van der Sluis, Reeni B Hildebrand, Bart Lammers, Ying Zhao, Domenico Praticò, Theo J C van Berkel, Patrick C N Rensen, Sander Kooijman, Matti Jauhiainen, Miranda van Eck. Disruption of Phospholipid Transfer Protein-Mediated High-Density Lipoprotein Maturation Reduces Scavenger Receptor BI Deficiency-Driven Atherosclerosis Susceptibility Despite Unexpected Metabolic Complications. Arteriosclerosis, thrombosis, and vascular biology. 2020 03; 40(3):611-623. doi: 10.1161/atvbaha.119.313862. [PMID: 31941380]
María J Limeres, Marc Suñé-Pou, Silvia Prieto-Sánchez, Cristina Moreno-Castro, Alejandro D Nusblat, Cristina Hernández-Munain, Guillermo R Castro, Carlos Suñé, Josep M Suñé-Negre, María L Cuestas. Development and characterization of an improved formulation of cholesteryl oleate-loaded cationic solid-lipid nanoparticles as an efficient non-viral gene delivery system. Colloids and surfaces. B, Biointerfaces. 2019 Dec; 184(?):110533. doi: 10.1016/j.colsurfb.2019.110533. [PMID: 31593829]
Marc Suñé-Pou, María J Limeres, Isaac Nofrerias, Anna Nardi-Ricart, Silvia Prieto-Sánchez, Younes El-Yousfi, Pilar Pérez-Lozano, Encarna García-Montoya, Montserrat Miñarro-Carmona, Josep Ramón Ticó, Cristina Hernández-Munain, Carlos Suñé, Josep Mª Suñé-Negre. Improved synthesis and characterization of cholesteryl oleate-loaded cationic solid lipid nanoparticles with high transfection efficiency for gene therapy applications. Colloids and surfaces. B, Biointerfaces. 2019 Aug; 180(?):159-167. doi: 10.1016/j.colsurfb.2019.04.037. [PMID: 31048241]
Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]
Marc Suñé-Pou, Silvia Prieto-Sánchez, Younes El Yousfi, Sofía Boyero-Corral, Anna Nardi-Ricart, Isaac Nofrerias-Roig, Pilar Pérez-Lozano, Encarna García-Montoya, Montserrat Miñarro-Carmona, Josep Ramón Ticó, Josep Mª Suñé-Negre, Cristina Hernández-Munain, Carlos Suñé. Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy. International journal of nanomedicine. 2018; 13(?):3223-3233. doi: 10.2147/ijn.s158884. [PMID: 29881274]
Alicja Wizert, D Robert Iskander, Lukasz Cwiklik. Interaction of lysozyme with a tear film lipid layer model: A molecular dynamics simulation study. Biochimica et biophysica acta. Biomembranes. 2017 Dec; 1859(12):2289-2296. doi: 10.1016/j.bbamem.2017.08.015. [PMID: 28847503]
Maaike Kockx, Elias Glaros, Betty Leung, Theodore W Ng, Jimmy F P Berbée, Virginie Deswaerte, Diana Nawara, Carmel Quinn, Kerry-Anne Rye, Wendy Jessup, Patrick C N Rensen, Peter J Meikle, Leonard Kritharides. Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia. Arteriosclerosis, thrombosis, and vascular biology. 2016 07; 36(7):1338-49. doi: 10.1161/atvbaha.115.307030. [PMID: 27150391]
Jia Li, Shancheng Ren, Hai-Long Piao, Fubo Wang, Peiyuan Yin, Chuanliang Xu, Xin Lu, Guozhu Ye, Yaping Shao, Min Yan, Xinjie Zhao, Yinghao Sun, Guowang Xu. Integration of lipidomics and transcriptomics unravels aberrant lipid metabolism and defines cholesteryl oleate as potential biomarker of prostate cancer. Scientific reports. 2016 Feb; 6(?):20984. doi: 10.1038/srep20984. [PMID: 26865432]
Peter J H Jones, Dylan S MacKay, Vijitha K Senanayake, Shuaihua Pu, David J A Jenkins, Philip W Connelly, Benoît Lamarche, Patrick Couture, Penny M Kris-Etherton, Sheila G West, Xiaoran Liu, Jennifer A Fleming, Roy R Hantgan, Lawrence L Rudel. High-oleic canola oil consumption enriches LDL particle cholesteryl oleate content and reduces LDL proteoglycan binding in humans. Atherosclerosis. 2015 Feb; 238(2):231-8. doi: 10.1016/j.atherosclerosis.2014.12.010. [PMID: 25528432]
Keisuke Matsuoka, Asumi Kase, Takashi Matsuo, Yusuke Ashida. Competitive Solubilization of Cholesterol/Cholesteryl Oleate and Seven Species of Sterol/Stanol in Model Intestinal Solution System. Journal of oleo science. 2015; 64(7):783-91. doi: 10.5650/jos.ess15044. [PMID: 26136176]
P Padmini S J Khedoe, Geerte Hoeke, Sander Kooijman, Wieneke Dijk, Jeroen T Buijs, Sander Kersten, Louis M Havekes, Pieter S Hiemstra, Jimmy F P Berbée, Mariëtte R Boon, Patrick C N Rensen. Brown adipose tissue takes up plasma triglycerides mostly after lipolysis. Journal of lipid research. 2015 Jan; 56(1):51-9. doi: 10.1194/jlr.m052746. [PMID: 25351615]
Tomohiko Shimizu, Shin-ichiro Miura, Hiroyuki Tanigawa, Takashi Kuwano, Bo Zhang, Yoshinari Uehara, Keijiro Saku. Rosuvastatin activates ATP-binding cassette transporter A1-dependent efflux ex vivo and promotes reverse cholesterol transport in macrophage cells in mice fed a high-fat diet. Arteriosclerosis, thrombosis, and vascular biology. 2014 Oct; 34(10):2246-53. doi: 10.1161/atvbaha.114.303715. [PMID: 25104799]
Yanbo Yang, Takashi Kuwano, William R Lagor, Carolyn J Albert, Siobhan Brenton, Daniel J Rader, David A Ford, Robert J Brown. Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. Lipids. 2014 Jun; 49(6):505-15. doi: 10.1007/s11745-014-3907-6. [PMID: 24777581]
Pipsa Kulovesi, Antti H Rantamäki, Juha M Holopainen. Surface properties of artificial tear film lipid layers: effects of wax esters. Investigative ophthalmology & visual science. 2014 May; 55(7):4448-54. doi: 10.1167/iovs.14-14122. [PMID: 24876287]
Otavio Celeste Mangili, Ana C Moron Gagliardi, Leonardo Celeste Mangili, Carlos H Mesquita, Luiz A Machado Cesar, Akira Tanaka, Ernst J Schaefer, Raul C Maranhão, Raul D Santos. Favorable effects of ezetimibe alone or in association with simvastatin on the removal from plasma of chylomicrons in coronary heart disease subjects. Atherosclerosis. 2014 Mar; 233(1):319-25. doi: 10.1016/j.atherosclerosis.2013.12.008. [PMID: 24503114]
John T Melchior, Janet K Sawyer, Kathryn L Kelley, Ramesh Shah, Martha D Wilson, Roy R Hantgan, Lawrence L Rudel. LDL particle core enrichment in cholesteryl oleate increases proteoglycan binding and promotes atherosclerosis. Journal of lipid research. 2013 Sep; 54(9):2495-503. doi: 10.1194/jlr.m039644. [PMID: 23804810]
François Briand, Quentin Thieblemont, Elodie Muzotte, Thierry Sulpice. Upregulating reverse cholesterol transport with cholesteryl ester transfer protein inhibition requires combination with the LDL-lowering drug berberine in dyslipidemic hamsters. Arteriosclerosis, thrombosis, and vascular biology. 2013 Jan; 33(1):13-23. doi: 10.1161/atvbaha.112.252932. [PMID: 23139291]
Shiro Watanabe, Koichi Tsuneyama. Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet. The Journal of toxicological sciences. 2013; 38(3):379-90. doi: 10.2131/jts.38.379. [PMID: 23665937]
J C Vinagre, C G Vinagre, F S Pozzi, E Slywitch, R C Maranhão. Metabolism of triglyceride-rich lipoproteins and transfer of lipids to high-density lipoproteins (HDL) in vegan and omnivore subjects. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2013 Jan; 23(1):61-7. doi: 10.1016/j.numecd.2011.02.011. [PMID: 21937206]
Won-Soo Lee. Integral hair lipid in human hair follicle. Journal of dermatological science. 2011 Dec; 64(3):153-8. doi: 10.1016/j.jdermsci.2011.08.004. [PMID: 21906914]
Bruno Mesmin, Nina H Pipalia, Frederik W Lund, Trudy F Ramlall, Anna Sokolov, David Eliezer, Frederick R Maxfield. STARD4 abundance regulates sterol transport and sensing. Molecular biology of the cell. 2011 Nov; 22(21):4004-15. doi: 10.1091/mbc.e11-04-0372. [PMID: 21900492]
Sofia L Souza, Kevin J Hallock, Sérgio S Funari, Winchil L C Vaz, James A Hamilton, Eurico Melo. Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid. Chemistry and physics of lipids. 2011 Oct; 164(7):664-71. doi: 10.1016/j.chemphyslip.2011.06.011. [PMID: 21756886]
Nobuhiro Zaima, Takeshi Sasaki, Hiroki Tanaka, Xian Wu Cheng, Kenji Onoue, Takahiro Hayasaka, Naoko Goto-Inoue, Hirofumi Enomoto, Naoki Unno, Masafumi Kuzuya, Mitsutoshi Setou. Imaging mass spectrometry-based histopathologic examination of atherosclerotic lesions. Atherosclerosis. 2011 Aug; 217(2):427-32. doi: 10.1016/j.atherosclerosis.2011.03.044. [PMID: 21514591]
Taichi Ohshiro, Daisuke Matsuda, Kent Sakai, Chiara Degirolamo, Hiroaki Yagyu, Lawrence L Rudel, Satoshi Omura, Shun Ishibashi, Hiroshi Tomoda. Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia. Arteriosclerosis, thrombosis, and vascular biology. 2011 May; 31(5):1108-15. doi: 10.1161/atvbaha.111.223552. [PMID: 21393580]
Andrew D Pucker, Mirunalni Thangavelu, Jason J Nichols. In vitro lipid deposition on hydrogel and silicone hydrogel contact lenses. Investigative ophthalmology & visual science. 2010 Dec; 51(12):6334-40. doi: 10.1167/iovs.10-5836. [PMID: 20702829]
Cristina P Almeida, Carolina G Vital, Thais C Contente, Durvanei A Maria, Raul C Maranhão. Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake. International journal of nanomedicine. 2010 Sep; 5(?):679-86. doi: 10.2147/ijn.s12293. [PMID: 20957219]
Michael R Paillasse, Philippe de Medina, Guillaume Amouroux, Loubna Mhamdi, Marc Poirot, Sandrine Silvente-Poirot. Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion. Journal of lipid research. 2009 Nov; 50(11):2203-11. doi: 10.1194/jlr.m800668-jlr200. [PMID: 19502590]
Artturi Koivuniemi, Mikko Heikelä, Petri T Kovanen, Ilpo Vattulainen, Marja T Hyvönen. Atomistic simulations of phosphatidylcholines and cholesteryl esters in high-density lipoprotein-sized lipid droplet and trilayer: clues to cholesteryl ester transport and storage. Biophysical journal. 2009 May; 96(10):4099-108. doi: 10.1016/j.bpj.2009.01.058. [PMID: 19450481]
Chiara Degirolamo, Gregory S Shelness, Lawrence L Rudel. LDL cholesteryl oleate as a predictor for atherosclerosis: evidence from human and animal studies on dietary fat. Journal of lipid research. 2009 Apr; 50 Suppl(?):S434-9. doi: 10.1194/jlr.r800076-jlr200. [PMID: 19029117]
S Mendes, S R Graziani, T S Vitório, A F Padoveze, R Hegg, S P Bydlowski, R C Maranhão. Uptake by breast carcinoma of a lipidic nanoemulsion after intralesional injection into the patients: a new strategy for neoadjuvant chemotherapy. Gynecologic oncology. 2009 Feb; 112(2):400-4. doi: 10.1016/j.ygyno.2008.10.018. [PMID: 19062081]
L Norlén, I Plasencia Gil, A Simonsen, P Descouts. Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films. Journal of structural biology. 2007 Jun; 158(3):386-400. doi: 10.1016/j.jsb.2006.12.006. [PMID: 17287132]
Mun-Chual Rho, Seung Woong Lee, Hye Ran Park, Jung-Ho Choi, Ji Yun Kang, Koanhoi Kim, Hyun Sun Lee, Young Kook Kim. ACAT inhibition of alkamides identified in the fruits of Piper nigrum. Phytochemistry. 2007 Mar; 68(6):899-903. doi: 10.1016/j.phytochem.2006.11.025. [PMID: 17188313]
J J Hosni, C G Vinagre, C Mady, R C Maranhão. Lipolysis of emulsion models of triglyceride-rich lipoproteins is altered in male patients with abdominal aorta aneurysm. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 2007 Mar; 40(3):305-7. doi: 10.1590/s0100-879x2007000300004. [PMID: 17334526]
Ketlin V Pinheiro, Vania T M Hungria, Elisabeth S Ficker, Claudete J Valduga, Carlos H Mesquita, Raul C Maranhão. Plasma kinetics of a cholesterol-rich microemulsion (LDE) in patients with Hodgkin's and non-Hodgkin's lymphoma and a preliminary study on the toxicity of etoposide associated with LDE. Cancer chemotherapy and pharmacology. 2006 May; 57(5):624-30. doi: 10.1007/s00280-005-0090-8. [PMID: 16133527]
Mikko Heikelä, Ilpo Vattulainen, Marja T Hyvönen. Atomistic simulation studies of cholesteryl oleates: model for the core of lipoprotein particles. Biophysical journal. 2006 Apr; 90(7):2247-57. doi: 10.1529/biophysj.105.069849. [PMID: 16399839]
Mariarosaria Napolitano, Elena Bravo. Evidence of dual pathways for lipid uptake during chylomicron remnant-like particle processing by human macrophages. Journal of vascular research. 2006; 43(4):355-66. doi: 10.1159/000094095. [PMID: 16791007]
Márcia M S Bernik, Joel C Heimann, Edna R Nakandakare, Patrícia M Cazita, Valéria S Nunes, Jussara C Rocha, Mônica Q T S Neves, Eder C R Quintão. Effects of hydrochlorothiazide and propranolol treatment on chylomicron metabolism in hypertensive objects. Canadian journal of physiology and pharmacology. 2005 Jul; 83(7):617-23. doi: 10.1139/y05-051. [PMID: 16091787]
Yassine Ben Ali, Frédéric Carrière, Robert Verger, Stefan Petry, Günter Muller, Abdelkarim Abousalham. Continuous monitoring of cholesterol oleate hydrolysis by hormone-sensitive lipase and other cholesterol esterases. Journal of lipid research. 2005 May; 46(5):994-1000. doi: 10.1194/jlr.m400509-jlr200. [PMID: 15716583]
Nilson R Melo, Maria C Latrilha, Raul D Santos, Luciano M Pompei, Raul C Maranhão. Effects in post-menopausal women of transdermal estrogen associated with progestin upon the removal from the plasma of a microemulsion that resembles low-density lipoprotein (LDL). Maturitas. 2005 Apr; 50(4):275-81. doi: 10.1016/j.maturitas.2004.05.009. [PMID: 15780526]
Carolina H M Azevedo, Jesus P Carvalho, Claudete J Valduga, Raul C Maranhão. Plasma kinetics and uptake by the tumor of a cholesterol-rich microemulsion (LDE) associated to etoposide oleate in patients with ovarian carcinoma. Gynecologic oncology. 2005 Apr; 97(1):178-82. doi: 10.1016/j.ygyno.2004.12.015. [PMID: 15790455]
Dwayne E Dove, Yan Ru Su, Wenwu Zhang, W Gray Jerome, Larry L Swift, MacRae F Linton, Sergio Fazio. ACAT1 deficiency disrupts cholesterol efflux and alters cellular morphology in macrophages. Arteriosclerosis, thrombosis, and vascular biology. 2005 Jan; 25(1):128-34. doi: 10.1161/01.atv.0000148323.94021.e5. [PMID: 15499044]
Renato J Alves, Jayme Diament, Rosângela F Amâncio, Neusa Forti, Raul C Maranhão. Lack of effect of captopril on the metabolism of an artificial lipid emulsion similar to chylomicrons in hypertensive hypercholesterolemic patients. Arquivos brasileiros de cardiologia. 2004 Dec; 83(6):512-5; 508. doi: 10.1590/s0066-782x2004001800009. [PMID: 15654448]
Robert Zimmermann, Juliane G Strauss, Guenter Haemmerle, Gabriele Schoiswohl, Ruth Birner-Gruenberger, Monika Riederer, Achim Lass, Georg Neuberger, Frank Eisenhaber, Albin Hermetter, Rudolf Zechner. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science (New York, N.Y.). 2004 Nov; 306(5700):1383-6. doi: 10.1126/science.1100747. [PMID: 15550674]
Camila G Puk, Carmen G C Vinagre, Edmar Bocchi, Fernando Bacal, Noedir Stolf, Raul C Maranhão. Plasma kinetics of a cholesterol-rich microemulsion in patients submitted to heart transplantation. Transplantation. 2004 Oct; 78(8):1177-81. doi: 10.1097/01.tp.0000137788.15004.7f. [PMID: 15502716]
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