glycolic acid (BioDeep_00000405201)
Main id: BioDeep_00000002845
PANOMIX_OTCML-2023
代谢物信息卡片
glycolic acid
化学式: C2H4O3 (76.016)
中文名称: 乙醇酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(=O)O)O
InChI: InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
描述信息
A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
D003879 - Dermatologic Agents > D007641 - Keratolytic Agents
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
同义名列表
4 个代谢物同义名
glycolic acid; Hydroxyethanoic acid; Glycolate; Glycolic acid
数据库引用编号
20 个数据库交叉引用编号
- ChEBI: CHEBI:17497
- KEGG: C00160
- KEGGdrug: D78078
- PubChem: 757
- DrugBank: DB03085
- ChEMBL: CHEMBL252557
- CAS: 79-14-1
- MoNA: FiehnHILIC001234
- MoNA: HMDB0000115_ms_ms_165
- MoNA: HMDB0000115_ms_ms_167
- MoNA: HMDB0000115_ms_ms_166
- MetaboLights: MTBLC17497
- PubChem: 3460
- KNApSAcK: C00007461
- PDB-CCD: GOA
- 3DMET: B01175
- NIKKAJI: J1.494J
- RefMet: Glycolic acid
- medchemexpress: HY-W015967
- KNApSAcK: 17497
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ajay S Kumar, D Prema, R Gagana Rao, J Prakash, P Balashanmugam, T Devasena, G Devanand Venkatasubbu. Fabrication of poly (lactic-co-glycolic acid)/gelatin electro spun nanofiber patch containing CaCO3/SiO2 nanocomposite and quercetin for accelerated diabetic wound healing.
International journal of biological macromolecules.
2024 Jan; 254(Pt 3):128060. doi:
10.1016/j.ijbiomac.2023.128060. [PMID: 37963500] - Yuanyuan Li, Chaojie Wang, Xile Deng, Runze Cai, Lidong Cao, Chong Cao, Li Zheng, Pengyue Zhao, Qiliang Huang. Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings.
International journal of molecular sciences.
2023 Jun; 24(12):. doi:
10.3390/ijms241210121. [PMID: 37373269] - Asghar Narmani, Roghayyeh Jahedi, Ehsan Bakhshian-Dehkordi, Saeid Ganji, Mahnaz Nemati, Ruhollah Ghahramani-Asl, Kave Moloudi, Seyed Mohammad Hosseini, Hamed Bagheri, Prashant Kesharwani, Ali Khani, Bagher Farhood, Amirhossein Sahebkar. Biomedical applications of PLGA nanoparticles in nanomedicine: Advances in drug delivery systems and cancer therapy.
Expert opinion on drug delivery.
2023 Jun; ?(?):. doi:
10.1080/17425247.2023.2223941. [PMID: 37294853] - Xiangyu Zhang, Santosh Kumar Misra, Parikshit Moitra, Xiuli Zhang, Se-Jin Jeong, Jeremiah Stitham, Astrid Rodriguez-Velez, Arick Park, Yu-Sheng Yeh, William E Gillanders, Daping Fan, Abhinav Diwan, Jaehyung Cho, Slava Epelman, Irfan J Lodhi, Dipanjan Pan, Babak Razani. Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis.
Autophagy.
2023 Mar; 19(3):886-903. doi:
10.1080/15548627.2022.2108252. [PMID: 35982578] - Yue Na, Ning Zhang, Xinyu Zhong, Jinlian Gu, Chang Yan, Shun Yin, Xia Lei, Jihui Zhao, Fang Geng. Polylactic-co-glycolic acid-based nanoparticles modified with peptides and other linkers cross the blood-brain barrier for targeted drug delivery.
Nanomedicine (London, England).
2023 01; 18(2):125-143. doi:
10.2217/nnm-2022-0287. [PMID: 36916394] - Jing Wei, Qianghua Quan, Peiyu Wang, Yiming Wang, Tong Huo, Quan An. Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling.
Cutaneous and ocular toxicology.
2022 Sep; 41(3):257-263. doi:
10.1080/15569527.2022.2109658. [PMID: 35920724] - Maomao Tang, Yuzhe Huang, Xiao Liang, Yaotian Tao, Ning He, Zhenbao Li, Jian Guo, Shuangying Gui. Sorafenib-Loaded PLGA-TPGS Nanosystems Enhance Hepatocellular Carcinoma Therapy Through Reversing P-Glycoprotein-Mediated Multidrug Resistance.
AAPS PharmSciTech.
2022 Apr; 23(5):130. doi:
10.1208/s12249-022-02214-y. [PMID: 35487999] - Giorgia Ceselin, Zoi Salta, Julien Bloino, Nicola Tasinato, Vincenzo Barone. Accurate Quantum Chemical Spectroscopic Characterization of Glycolic Acid: A Route Toward its Astrophysical Detection.
The journal of physical chemistry. A.
2022 Apr; 126(15):2373-2387. doi:
10.1021/acs.jpca.2c01419. [PMID: 35384666] - Shengtang Li, Xuewen Shi, Bo Xu, Jian Wang, Peng Li, Xin Wang, Jinpeng Lou, Ziyao Li, Chengwei Yang, Songkai Li, Ping Zhen. In vitro drug release and antibacterial activity evaluation of silk fibroin coated vancomycin hydrochloride loaded poly (lactic-co-glycolic acid) (PLGA) sustained release microspheres.
Journal of biomaterials applications.
2022 04; 36(9):1676-1688. doi:
10.1177/08853282211064098. [PMID: 35015589] - Avni Nautiyal, Sarika Wairkar. Management of hyperpigmentation: Current treatments and emerging therapies.
Pigment cell & melanoma research.
2021 11; 34(6):1000-1014. doi:
10.1111/pcmr.12986. [PMID: 33998768] - Ankang Gu, Litao Zhang, Faku Ma, Xiangjun Kong. Induction of localized bullous pemphigoid on a young woman following a chemical peel.
Indian journal of dermatology, venereology and leprology.
2021 Sep; 87(5):706-708. doi:
10.25259/ijdvl_1116_20. [PMID: 34379953] - Pouria Jarsiah, Joerg Roehrich, Theresa Kueting, Walter Martz, Cornelius Hess. GHB related acids are useful in routine casework of suspected GHB intoxication cases.
Forensic science international.
2021 Jul; 324(?):110833. doi:
10.1016/j.forsciint.2021.110833. [PMID: 34020075] - Yaacov Frishberg, Georges Deschênes, Jaap W Groothoff, Sally-Anne Hulton, Daniella Magen, Jérôme Harambat, William G Van't Hoff, Ulrike Lorch, Dawn S Milliner, John C Lieske, Patrick Haslett, Pushkal P Garg, Akshay K Vaishnaw, Sandeep Talamudupula, Jiandong Lu, Bahru A Habtemariam, David V Erbe, Tracy L McGregor, Pierre Cochat. Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1: A Placebo-Controlled Randomized Clinical Trial.
Clinical journal of the American Society of Nephrology : CJASN.
2021 07; 16(7):1025-1036. doi:
10.2215/cjn.14730920. [PMID: 33985991] - Maryam Pourhajibagher, Maryam Azimi, Vahid Haddadi-Asl, Hanie Ahmadi, Mehrdad Gholamzad, Sara Ghorbanpour, Abbas Bahador. Robust antimicrobial photodynamic therapy with curcumin-poly (lactic-co-glycolic acid) nanoparticles against COVID-19: A preliminary in vitro study in Vero cell line as a model.
Photodiagnosis and photodynamic therapy.
2021 Jun; 34(?):102286. doi:
10.1016/j.pdpdt.2021.102286. [PMID: 33838311] - Xin-Jian Li, Yun You, Qiong-Ling Zhang, Bing-Bing Zhang, Lin Yan, Ze-Min Ou, Yao Zhang, Yan-Jing Wang, Yan Tong, De-Wen Liu, Jin-Yu Wang. [Preparation of paclitaxel-loaded and folic acid-modified poly (lactic-co-glycolic acid) nano-micelles and in vitro anticancer effect on cervical cancer HeLa cells].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2021 May; 46(10):2481-2488. doi:
10.19540/j.cnki.cjcmm.20210302.303. [PMID: 34047094] - Ning Wu, Jia Liu, Weibo Ma, Xian Dong, Feng Wang, Dicheng Yang, Yan Xu. Degradable calcium deficient hydroxyapatite/poly(lactic-glycolic acid copolymer) bilayer scaffold through integral molding 3D printing for bone defect repair.
Biofabrication.
2021 03; 13(2):. doi:
10.1088/1758-5090/abcb48. [PMID: 33202398] - Pouria Jarsiah, Theresa Kueting, Joerg Roehrich, Tanja Germerott, Daniela Remane, Stefan W Toennes, Stefan Scholtis, Franziska Krumbiegel, Cornelius Hess. GHB related acids (dihydroxy butyric acids, glycolic acid) can help in the interpretation of post mortem GHB results.
Forensic science international.
2020 Nov; 316(?):110536. doi:
10.1016/j.forsciint.2020.110536. [PMID: 33096454] - David Wiegmann, Lori Haddad. Two is better than one: The combined effects of glycolic acid and salicylic acid on acne-related disorders.
Journal of cosmetic dermatology.
2020 Sep; 19(9):2349-2351. doi:
10.1111/jocd.13387. [PMID: 32250551] - Hudson K Takano, Roland Beffa, Christopher Preston, Philip Westra, Franck E Dayan. A novel insight into the mode of action of glufosinate: how reactive oxygen species are formed.
Photosynthesis research.
2020 Jun; 144(3):361-372. doi:
10.1007/s11120-020-00749-4. [PMID: 32372199] - Amira Amin Zayed, Rehab Mohamed Sobhi, Randa Mohamed Saleh El Aguizy, Dina Sabry, Sara Bahaa Mahmoud. Sequential peeling as a monotherapy for treatment of milder forms of acne vulgaris.
Journal of cosmetic dermatology.
2020 Jun; 19(6):1381-1387. doi:
10.1111/jocd.13162. [PMID: 31545017] - Tracy L McGregor, Karen A Hunt, Elaine Yee, Dan Mason, Paul Nioi, Simina Ticau, Marissa Pelosi, Perry R Loken, Sarah Finer, Deborah A Lawlor, Eric B Fauman, Qin Qin Huang, Christopher J Griffiths, Daniel G MacArthur, Richard C Trembath, Devin Oglesbee, John C Lieske, David V Erbe, John Wright, David A van Heel. Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria.
eLife.
2020 03; 9(?):. doi:
10.7554/elife.54363. [PMID: 32207686] - Brianna Buchalski, Kyle D Wood, Anil Challa, Sonia Fargue, Ross P Holmes, W Todd Lowther, John Knight. The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria.
Biochimica et biophysica acta. Molecular basis of disease.
2020 03; 1866(3):165633. doi:
10.1016/j.bbadis.2019.165633. [PMID: 31821850] - Agni Kumar Biswal, Hariprasad P, Sampa Saha. Efficient and prolonged antibacterial activity from porous PLGA microparticles and their application in food preservation.
Materials science & engineering. C, Materials for biological applications.
2020 Mar; 108(?):110496. doi:
10.1016/j.msec.2019.110496. [PMID: 31923956] - Dewi van Harskamp, Sander F Garrelfs, Michiel J S Oosterveld, Jaap W Groothoff, Johannes B van Goudoever, Henk Schierbeek. Development and Validation of a New Gas Chromatography-Tandem Mass Spectrometry Method for the Measurement of Enrichment of Glyoxylate Metabolism Analytes in Hyperoxaluria Patients Using a Stable Isotope Procedure.
Analytical chemistry.
2020 01; 92(2):1826-1832. doi:
10.1021/acs.analchem.9b03670. [PMID: 31867958] - Yusuke Marikawa, Hong-Ru Chen, Mark Menor, Youping Deng, Vernadeth B Alarcon. Exposure-based assessment of chemical teratogenicity using morphogenetic aggregates of human embryonic stem cells.
Reproductive toxicology (Elmsford, N.Y.).
2020 01; 91(?):74-91. doi:
10.1016/j.reprotox.2019.10.004. [PMID: 31711903] - Shun Li, Qian Xu, Liang Zhao, Chengkun Ye, Lei Hua, Jun Liang, Rutong Yu, Hongmei Liu. Angiopep-2 Modified Cationic Lipid-Poly-Lactic-Co-Glycolic Acid Delivery Temozolomide and DNA Repair Inhibitor Dbait to Achieve Synergetic Chemo-Radiotherapy Against Glioma.
Journal of nanoscience and nanotechnology.
2019 12; 19(12):7539-7545. doi:
10.1166/jnn.2019.16775. [PMID: 31196258] - Ramasubba Reddy Palem, Kummara Madhusudana Rao, Tae June Kang. Self-healable and dual-functional guar gum-grafted-polyacrylamidoglycolic acid-based hydrogels with nano-silver for wound dressings.
Carbohydrate polymers.
2019 Nov; 223(?):115074. doi:
10.1016/j.carbpol.2019.115074. [PMID: 31427000] - Seong Kwang Lim, Jean Yoo, Haewon Kim, Woong Kim, Ilseob Shim, Byung-Il Yoon, Pilje Kim, Seung DO Yu, Ig-Chun Eom. Acute and 28-Day Repeated Inhalation Toxicity Study of Glycolic Acid in Male Sprague-Dawley Rats.
In vivo (Athens, Greece).
2019 Sep; 33(5):1507-1519. doi:
10.21873/invivo.11631. [PMID: 31471399] - Marion Eisenhut, Marc-Sven Roell, Andreas P M Weber. Mechanistic understanding of photorespiration paves the way to a new green revolution.
The New phytologist.
2019 09; 223(4):1762-1769. doi:
10.1111/nph.15872. [PMID: 31032928] - Allen Rodgers, Phindile Cele, Neil Ravenscroft, Cesarina Edmonds-Smith, Graham Jackson. Theoretical and laboratory investigations of the effects of hydroxyproline ingestion on the metabolic and physicochemical risk factors for calcium oxalate kidney stone formation in a small group of healthy subjects.
International urology and nephrology.
2019 Jul; 51(7):1121-1127. doi:
10.1007/s11255-019-02186-2. [PMID: 31161522] - Maria Michelle Papamichael, Charis Katsardis, Bircan Erbas, Catherine Itsiopoulos, Dimitris Tsoukalas. Urinary organic acids as biomarkers in the assessment of pulmonary function in children with asthma.
Nutrition research (New York, N.Y.).
2019 01; 61(?):31-40. doi:
10.1016/j.nutres.2018.10.004. [PMID: 30683437] - Gaspar Tuero, Jesús González, Laura Sahuquillo, Anna Freixa, Isabel Gomila, Miguel Ángel Elorza, Bernardino Barceló. Value of glycolic acid analysis in ethylene glycol poisoning: A clinical case report and systematic review of the literature.
Forensic science international.
2018 Sep; 290(?):e9-e14. doi:
10.1016/j.forsciint.2018.07.007. [PMID: 30055870] - Pavol Ďurč, František Foret, Petr Kubáň. Fast blood plasma separation device for point-of-care applications.
Talanta.
2018 Jun; 183(?):55-60. doi:
10.1016/j.talanta.2018.02.004. [PMID: 29567189] - Sonia Fargue, Dawn S Milliner, John Knight, Julie B Olson, W Todd Lowther, Ross P Holmes. Hydroxyproline Metabolism and Oxalate Synthesis in Primary Hyperoxaluria.
Journal of the American Society of Nephrology : JASN.
2018 06; 29(6):1615-1623. doi:
10.1681/asn.2017040390. [PMID: 29588429] - Chunlin Chen, Haibin Wang, Guozhang Zhu, Zhongsheng Sun, Xiang Xu, Fangwei Li, Shengkang Luo. Three-dimensional poly lactic-co-glycolic acid scaffold containing autologous platelet-rich plasma supports keloid fibroblast growth and contributes to keloid formation in a nude mouse model.
Journal of dermatological science.
2018 Jan; 89(1):67-76. doi:
10.1016/j.jdermsci.2017.07.020. [PMID: 29122407] - Oliver Clifford-Mobley, Gill Rumsby, Swati Kanodia, Mohammed Didi, Richard Holt, Senthil Senniappan. Glycolate oxidase deficiency in a patient with congenital hyperinsulinism and unexplained hyperoxaluria.
Pediatric nephrology (Berlin, Germany).
2017 Nov; 32(11):2159-2163. doi:
10.1007/s00467-017-3741-1. [PMID: 28752386] - Tapan K Bhattacharyya, Hope Bueller, Yvonne Hsia, J Regan Thomas. Dermal Histology in Mouse Skin Exposed to Cosmeceuticals.
Facial plastic surgery : FPS.
2017 Oct; 33(5):545-550. doi:
10.1055/s-0037-1605600. [PMID: 28962062] - Emmanuel Richard, Jean-Marc Blouin, Jérome Harambat, Brigitte Llanas, Stéphane Bouchet, Cécile Acquaviva, Renaud de la Faille. Late diagnosis of primary hyperoxaluria type III.
Annals of clinical biochemistry.
2017 May; 54(3):406-411. doi:
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Photosynthesis research.
2017 May; 132(2):183-196. doi:
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Plant physiology.
2017 04; 173(4):2010-2028. doi:
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Methods in molecular biology (Clifton, N.J.).
2017; 1653(?):97-104. doi:
10.1007/978-1-4939-7225-8_7. [PMID: 28822128] - Leonardo Perez de Souza, Marek Szecówka, Alisdair R Fernie, Takayuki Tohge. 13CO2 Labeling and Mass Spectral Analysis of Photorespiration.
Methods in molecular biology (Clifton, N.J.).
2017; 1653(?):157-166. doi:
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Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.
2016 Dec; 24(12):911-915. doi:
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Phytochemistry.
2016 Dec; 132(?):26-32. doi:
10.1016/j.phytochem.2016.09.009. [PMID: 27665682] - Oliver Clifford-Mobley, Laura Hewitt, Gill Rumsby. Simultaneous analysis of urinary metabolites for preliminary identification of primary hyperoxaluria.
Annals of clinical biochemistry.
2016 Jul; 53(Pt 4):485-94. doi:
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Photosynthesis research.
2016 Jul; 129(1):93-103. doi:
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Biochimica et biophysica acta.
2016 06; 1862(6):1055-62. doi:
10.1016/j.bbadis.2016.02.004. [PMID: 26854734] - Younès Dellero, Mathieu Jossier, Jessica Schmitz, Veronica G Maurino, Michael Hodges. Photorespiratory glycolate-glyoxylate metabolism.
Journal of experimental botany.
2016 05; 67(10):3041-52. doi:
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Journal of experimental botany.
2016 05; 67(10):3165-75. doi:
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The Plant journal : for cell and molecular biology.
2015 Nov; 84(4):718-32. doi:
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Journal of pharmaceutical and biomedical analysis.
2015 Oct; 114(?):16-21. doi:
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Plant physiology.
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Journal of analytical toxicology.
2015 Jul; 39(6):481-5. doi:
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Clinical biochemistry.
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The Journal of biological chemistry.
2015 Jan; 290(3):1885-97. doi:
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PloS one.
2015; 10(3):e0118804. doi:
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Journal of biomaterials science. Polymer edition.
2015; 26(8):497-514. doi:
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The AAPS journal.
2015 Jan; 17(1):256-67. doi:
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Talanta.
2014 Dec; 130(?):470-4. doi:
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Annals of surgical oncology.
2014 Dec; 21 Suppl 4(?):S736-42. doi:
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