dimethoate (BioDeep_00000403436)
natural product Industrial Pollutants
代谢物信息卡片
Pesticide1_Dimethoate_C5H12NO3PS2_Phosphorodithioic acid, O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] ester
化学式: C5H12NO3PS2 (228.9996)
中文名称: 乐果
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CNC(=O)CSP(=S)(OC)OC
InChI: InChI=1S/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)
描述信息
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
D010575 - Pesticides > D007306 - Insecticides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals
CONFIDENCE standard compound; INTERNAL_ID 3009
同义名列表
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:34714
- PubChem: 3082
- ChEMBL: CHEMBL1569524
- MeSH: Dimethoate
- CAS: 60-51-5
- MoNA: AU300911
- MoNA: AU300910
- MoNA: AU300909
- MoNA: AU300908
- MoNA: AU300907
- MoNA: CCMSLIB00001058697
- MoNA: CCMSLIB00001058686
- MoNA: CCMSLIB00001058645
- MoNA: CCMSLIB00001058701
- MoNA: CCMSLIB00001058695
- RefMet: Dimethoate
- KEGG: C14326
- PubChem: 17395326
- KNApSAcK: 34714
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yu-Jie Liang, Ding-Xin Long, Shanshan Wang, Hui-Ping Wang, Yi-Jun Wu. Metabolomic analysis of the serum and urine of rats exposed to diazinon, dimethoate, and cypermethrin alone or in combination.
BMC pharmacology & toxicology.
2024 01; 25(1):3. doi:
10.1186/s40360-023-00714-6. [PMID: 38167230] - Dalya Belhassen, Safa Bejaoui, Roberto Martins, Fernando Perina, Joana Figueiredo, Boutheina Ben Abdallah, Zeineb Khila, Samir Boubaker, Chayma Ben Fayala, Monia Trabelsi, Nejla Soudani. Alteration of redox status and fatty acid profile in gills from the green crab (Carcinus aestuarii) following dimethoate exposure.
Pesticide biochemistry and physiology.
2023 Dec; 197(?):105699. doi:
10.1016/j.pestbp.2023.105699. [PMID: 38072554] - Nils Schöfer, Julian Ackermann, Julian Hoheneder, John Hofferberth, Joachim Ruther. Sublethal effects of four insecticides targeting cholinergic neurons on partner and host finding in the parasitic wasp Nasonia vitripennis.
Environmental toxicology and chemistry.
2023 Jul; ?(?):. doi:
10.1002/etc.5721. [PMID: 37477474] - Valeria Medoro, Giacomo Ferretti, Annalisa Rotondi, Lucia Morrone, Barbara Faccini, Massimo Coltorti. Incidence of foliar treatments and geographical origin on the geochemical fingerprints of leaves and fruits in olive growing.
Environmental geochemistry and health.
2023 Jul; 45(7):4643-4664. doi:
10.1007/s10653-023-01519-6. [PMID: 36892789] - Timothy B Dang, Ana M Vélez, Arnubio Valencia-Jiménez, Jordan D Reinders, Emily E Stricklin, Matthew W Carroll, Clinton D Pilcher, Jeffrey T Krumm, Graham P Head, Lance J Meinke. Characterization of western corn rootworm (Coleoptera: Chrysomelidae) susceptibility to foliar insecticides in northeast Nebraska.
Journal of economic entomology.
2023 Apr; ?(?):. doi:
10.1093/jee/toad067. [PMID: 37032524] - Pratibha Singh, Madhulika Singh, Sunita Kumari Singh, Sheo Mohan Prasad. Application of soil amendments mitigates phytotoxic effects on Solanum melongena L. and Lycopersicon esculentum L. seedlings exposed to chlorpyrifos and dimethoate pesticides.
Environmental science and pollution research international.
2023 Apr; ?(?):. doi:
10.1007/s11356-023-26696-w. [PMID: 37016262] - Wenhong Li, Lu Lv, Yanhua Wang, Yu-Cheng Zhu. Mixture effects of thiamethoxam and seven pesticides with different modes of action on honey bees (Aplis mellifera).
Scientific reports.
2023 Feb; 13(1):2679. doi:
10.1038/s41598-023-29837-w. [PMID: 36792894] - Jitendra Kumar Pandey, Gunjan Dubey, R Gopal. Prolonged Use of Insecticide Dimethoate Inhibits Growth and Photosynthetic Activity of Wheat Seedlings: A Study by Laser-Induced Chlorophyll Fluorescence Spectroscopy.
Journal of fluorescence.
2022 Nov; 32(6):2159-2172. doi:
10.1007/s10895-022-03010-4. [PMID: 35970986] - Jessica L Krob, Scott D Stewart, Sebe A Brown, Dawson Kerns, Scott H Graham, Clay Perkins, Anders S Huseth, George G Kennedy, Dominic D Reisig, Sally V Taylor, Tyler B Towles, David L Kerns, Benjamin C Thrash, Gus M Lorenz, Nick R Bateman, Don R Cook, Whitney D Crow, Jeffrey Gore, Angus L Catchot, Fred R Musser, Beverly Catchot. Standardized Field Trials in Cotton and Bioassays to Evaluate Resistance of Tobacco Thrips (Thysanoptera: Thripidae) to Insecticides in the Southern United States.
Journal of economic entomology.
2022 10; 115(5):1693-1702. doi:
10.1093/jee/toac136. [PMID: 36099406] - Felicia Kueh Tai, David E Pattemore, Mateusz Jochym, Jacqueline R Beggs, Grant L Northcott, Ashley N Mortensen. Honey bee toxicological responses do not accurately predict environmental risk of imidacloprid to a solitary ground-nesting bee species.
The Science of the total environment.
2022 Sep; 839(?):156398. doi:
10.1016/j.scitotenv.2022.156398. [PMID: 35654201] - Saliha Ahmad, Ana Paula Pinto, Faisal Ibney Hai, Mohamed El-Taher Ibrahim Badawy, Refugio Rodriguez Vazquez, Tatheer Alam Naqvi, Farooq Hussain Munis, Tariq Mahmood, Hassan Javed Chaudhary. Dimethoate residues in Pakistan and mitigation strategies through microbial degradation: a review.
Environmental science and pollution research international.
2022 Jul; 29(34):51367-51383. doi:
10.1007/s11356-022-20933-4. [PMID: 35616845] - Ravi Pandiselvam, Rathnakumar Kaavya, Anandu Chandra Khanashyam, Valarivan Divya, Sajeeb Khan Abdullah, Fawzan Sigma Aurum, Rajendran Dakshyani, Anjineyulu Kothakota, Shunmugiah Veluchamy Ramesh, Amin Mousavi Khaneghah. Research trends and emerging physical processing technologies in mitigation of pesticide residues on various food products.
Environmental science and pollution research international.
2022 Jun; 29(30):45131-45149. doi:
10.1007/s11356-022-20338-3. [PMID: 35474428] - Ratnamma Pasar, Pallavi Ms, Harischandra Naik R, Devaraj M, Nandini P, Bheemanna M, Badariprasad P R, Paramasivam M. Simultaneous determination of dimethoate and its metabolite omethoate in curry leaf using LC-MS/MS and risk assessment.
Journal of separation science.
2022 Jun; 45(11):1831-1838. doi:
10.1002/jssc.202100696. [PMID: 35315569] - Samira Musa Sasi, Nagia Musa Alghoul, Nuri Awayn, Ahmed Elghoul. Positive effect of green tea extract on reproductive toxicity induced by dimethoate in male mice.
Open veterinary journal.
2022 Mar; 12(2):165-170. doi:
10.5455/ovj.2022.v12.i2.2. [PMID: 35603062] - Yujuan Xu, Hongliang Gao, Zhixiang Du, He Liu, Qi Cheng, Furong Zhang, Juan Ye, Aiqing Wang, Yanjun Dou, Bei Ma, Ningwei Zhao, Feng Zhu, Xianlin Xu, Ning Shen, Jing Wu, Bin Xue. A new approach for reducing pollutants level: a longitudinal cohort study of physical exercises in young people.
BMC public health.
2022 02; 22(1):223. doi:
10.1186/s12889-022-12621-2. [PMID: 35114971] - Saliha Ahmad, Hassan Javed Chaudhary, Christos A Damalas. Microbial detoxification of dimethoate through mediated hydrolysis by Brucella sp. PS4: molecular profiling and plant growth-promoting traits.
Environmental science and pollution research international.
2022 Jan; 29(2):2420-2431. doi:
10.1007/s11356-021-15806-1. [PMID: 34374007] - Yu-Juan Xu, Hong-Liang Gao, He Liu, Ning-Wei Zhao, Qi Cheng, Fu-Rong Zhang, Juan Ye, Ai-Qing Wang, Yan-Jun Dou, Bei Ma, Feng Zhu, Xian-Lin Xu, Chao-Jun Li, Jing Wu, Ning Shen, Bin Xue. Urinary levels of dimethoate, bisphenol A and benzo[a]pyrene in first-year students of Hohai University from different geographical regions.
BMC public health.
2021 09; 21(1):1692. doi:
10.1186/s12889-021-11726-4. [PMID: 34530795] - Mercedes Acquaroni, Julieta Peluso, Gabriela Svartz, Carolina Aronzon, Cristina Pérez Coll. Characterization of acute toxicity, genotoxicity, and oxidative stress of dimethoate in Rhinella arenarum larvae.
Environmental science and pollution research international.
2021 Aug; 28(31):41772-41779. doi:
10.1007/s11356-021-13691-2. [PMID: 33791959] - Xiaoshan Zhou, Xinling Li, Wan Wei, Xiaoran Duan, Hui Zhang, Mingcui Ding, Wu Yao, Qi Wang, Wei Wang, Yongli Yang. Association between genetic polymorphisms of telomere pathway genes and hydrogen peroxide level in omethoate exposure workers.
Environmental toxicology and pharmacology.
2021 Feb; 82(?):103541. doi:
10.1016/j.etap.2020.103541. [PMID: 33161111] - Tuanwei Wang, Hui Zhang, Lei Li, Wenjuan Zhang, Qi Wang, Wei Wang. Plasma cholinesterase activity is influenced by interactive effect between omethoate exposure and CYP2E1 polymorphisms.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2021; 56(5):477-482. doi:
10.1080/03601234.2021.1911517. [PMID: 33872129] - Elçin Bakır, Serpil Sarıözkan, Burcu Ünlü Endirlik, Ayşe Baldemir Kılıç, Arzu Hanım Yay, Fazile Cantürk Tan, Ayşe Eken, Gaffari Türk. Cherry laurel fruit extract counters dimethoate-induced reproductive impairment and testicular apoptosis.
Arhiv za higijenu rada i toksikologiju.
2020 Dec; 71(4):329-338. doi:
10.2478/aiht-2020-71-3412. [PMID: 33410775] - Catarina Malheiro, Diogo N Cardoso, Joana Neves, Diana L D Lima, Valdemar Inocêncio Esteves, Amadeu M V M Soares, Susana Loureiro. Biochar in soil mitigates dimethoate hazard to soil pore water exposed biota.
Journal of hazardous materials.
2020 12; 400(?):123304. doi:
10.1016/j.jhazmat.2020.123304. [PMID: 32947708] - Feng Zheng, Hui Jiang, Jinliang Jia, Ruifei Wang, Zhixiang Zhang, Hanhong Xu. Effect of dimethoate in controlling Monolepta hieroglyphica (Motschulsky) and its distribution in maize by drip irrigation.
Pest management science.
2020 Apr; 76(4):1523-1530. doi:
10.1002/ps.5670. [PMID: 31686420] - Yaoyao Dong, Yiyan Wang, Qiqi Zhu, Xiaoheng Li, Tongliang Huang, Huitao Li, Junzhao Zhao, Ren-Shan Ge. Dimethoate blocks pubertal differentiation of Leydig cells in rats.
Chemosphere.
2020 Feb; 241(?):125036. doi:
10.1016/j.chemosphere.2019.125036. [PMID: 31606569] - Aline Romero-Natale, Georgette Rebollar-Pérez, Irmene Ortiz, María Guadalupe Tenorio-Arvide, Ricardo Munguía-Pérez, Ilaria Palchetti, Eduardo Torres. A simple spectroscopic method to determine dimethoate in water samples by complex formation.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2020; 55(4):310-318. doi:
10.1080/03601234.2019.1696095. [PMID: 31782687] - Sinue I Morales, Ana M Martínez, José I Figueroa, Jesús Campos-García, Alberto Gómez-Tagle, Philippe Lobit, Guy Smagghe, Samuel Pineda. Foliar persistence and residual activity of four insecticides of different mode of action on the predator Engytatus varians (Hemiptera: Miridae).
Chemosphere.
2019 Nov; 235(?):76-83. doi:
10.1016/j.chemosphere.2019.06.163. [PMID: 31255768] - Tatjana Mitrović, Saša Lazović, Branislav Nastasijević, Igor A Pašti, Vesna Vasić, Tamara Lazarević-Pašti. Non-thermal plasma needle as an effective tool in dimethoate removal from water.
Journal of environmental management.
2019 Sep; 246(?):63-70. doi:
10.1016/j.jenvman.2019.05.143. [PMID: 31174031] - Daniel E Martin, Mohamed A Latheef. Aerial application methods control spider mites on corn in Kansas, USA.
Experimental & applied acarology.
2019 Apr; 77(4):571-582. doi:
10.1007/s10493-019-00367-3. [PMID: 31093857] - Lorenzo Tognaccini, Marilena Ricci, Cristina Gellini, Alessandro Feis, Giulietta Smulevich, Maurizio Becucci. Surface Enhanced Raman Spectroscopy for In-Field Detection of Pesticides: A Test on Dimethoate Residues in Water and on Olive Leaves.
Molecules (Basel, Switzerland).
2019 Jan; 24(2):. doi:
10.3390/molecules24020292. [PMID: 30650543] - Verena Christen, Yvonne Joho, Maren Vogel, Karl Fent. Transcriptional and physiological effects of the pyrethroid deltamethrin and the organophosphate dimethoate in the brain of honey bees (Apis mellifera).
Environmental pollution (Barking, Essex : 1987).
2019 Jan; 244(?):247-256. doi:
10.1016/j.envpol.2018.10.030. [PMID: 30340169] - Yahya Saleh Al-Awthan, Omar Salem Bahattab. Protective Role of Carissa edulis Ethanolic Extract Against Dimethoate-induced Hepatotoxicity in Guinea Pigs.
Pakistan journal of biological sciences : PJBS.
2019 Jan; 22(6):299-308. doi:
10.3923/pjbs.2019.299.308. [PMID: 31930853] - Andreas Kranawetvogl, Markus Siegert, Florian Eyer, Horst Thiermann, Harald John. Verification of organophosphorus pesticide poisoning: Detection of phosphorylated tyrosines and a cysteine-proline disulfide-adduct from human serum albumin after intoxication with dimethoate/omethoate.
Toxicology letters.
2018 Dec; 299(?):11-20. doi:
10.1016/j.toxlet.2018.08.013. [PMID: 30165092] - Maryam Rezaei Shadegan, Mahdi Banaee. Effects of dimethoate alone and in combination with Bacilar fertilizer on oxidative stress in common carp, Cyprinus carpio.
Chemosphere.
2018 Oct; 208(?):101-107. doi:
10.1016/j.chemosphere.2018.05.177. [PMID: 29860141] - Mingcui Ding, Yongli Yang, Xiaoran Duan, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Suxiang Liu, Lei Li, Junling Liu, Lixia Tang, Xinhua Niu, Yuhong Zhang, Guoyu Li, Wu Yao, Liuxin Cui, Wei Wang. Association of genetic polymorphisms of telomere binding proteins with cholinesterase activity in omethoate-exposed workers.
Ecotoxicology and environmental safety.
2018 10; 161(?):563-568. doi:
10.1016/j.ecoenv.2018.06.036. [PMID: 29929132] - Pratibha Singh, Sheo Mohan Prasad. Antioxidant enzyme responses to the oxidative stress due to chlorpyrifos, dimethoate and dieldrin stress in palak (Spinacia oleracea L.) and their toxicity alleviation by soil amendments in tropical croplands.
The Science of the total environment.
2018 Jul; 630(?):839-848. doi:
10.1016/j.scitotenv.2018.02.203. [PMID: 29499539] - Dalia I A Mesallam, Omaima I Abdel Hamid, Nahla E Ibrahem. Ethanolic extract of fenugreek seeds moderates dimethoate-induced pancreatic damage in male rats.
Environmental science and pollution research international.
2018 Feb; 25(4):3894-3904. doi:
10.1007/s11356-017-0749-9. [PMID: 29177779] - Xiangying Liu, Yu Li, Xuguo Zhou, Kun Luo, Lifeng Hu, Kailin Liu, Lianyang Bai. Photocatalytic degradation of dimethoate in Bok choy using cerium-doped nano titanium dioxide.
PloS one.
2018; 13(5):e0197560. doi:
10.1371/journal.pone.0197560. [PMID: 29771967] - Ikram Jaabiri Kamoun, Olukayode O Jegede, Olugbenga J Owojori, Jalel Bouzid, Radhia Gargouri, Jörg Römbke. Effects of deltamethrin, dimethoate, and chlorpyrifos on survival and reproduction of the collembolan Folsomia candida and the predatory mite Hypoaspis aculeifer in two African and two European soils.
Integrated environmental assessment and management.
2018 Jan; 14(1):92-104. doi:
10.1002/ieam.1966. [PMID: 28755498] - Kejun Yang, Yifei Zhang, Lianhua Zhu, Zuotong Li, Benliang Deng. Omethoate treatment mitigates high salt stress inhibited maize seed germination.
Pesticide biochemistry and physiology.
2018 Jan; 144(?):79-82. doi:
10.1016/j.pestbp.2017.12.001. [PMID: 29463412] - Ruyan Hou, Mengmeng Tong, Wanjun Gao, Lei Wang, Tianxi Yang, Lili He. Investigation of degradation and penetration behaviors of dimethoate on and in spinach leaves using in situ SERS and LC-MS.
Food chemistry.
2017 Dec; 237(?):305-311. doi:
10.1016/j.foodchem.2017.05.117. [PMID: 28764001] - Lucia Mainero Rocca, Juri Cecca, Nunziata L'Episcopo, Giovanni Fabrizi. Ambient mass spectrometry: Direct analysis of dimethoate, tebuconazole, and trifloxystrobin on olive and vine leaves by desorption electrospray ionization interface.
Journal of mass spectrometry : JMS.
2017 Nov; 52(11):709-719. doi:
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Chemosphere.
2017 May; 175(?):36-44. doi:
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Environmental toxicology.
2017 Apr; 32(4):1202-1212. doi:
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Fish physiology and biochemistry.
2017 Apr; 43(2):455-464. doi:
10.1007/s10695-016-0299-y. [PMID: 27714546] - Madhusudan Reddy Narra. Haematological and immune upshots in Clarias batrachus exposed to dimethoate and defying response of dietary ascorbic acid.
Chemosphere.
2017 Feb; 168(?):988-995. doi:
10.1016/j.chemosphere.2016.10.112. [PMID: 27816289] - Yahya Saleh Al-Awthan, Mohamed Ali Al-Duais, Amany Abdulfatah Hazeb, Waleed Ahmed Alril. Protective Role of Achillea biebersteinii Pretreatment on Dimethoate Induced Oxidative Stress in Guinea Pigs Liver.
Pakistan journal of biological sciences : PJBS.
2017; 20(8):403-409. doi:
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Journal of agricultural and food chemistry.
2016 Nov; 64(45):8491-8498. doi:
10.1021/acs.jafc.6b03334. [PMID: 27771954] - Sandra Halwachs, Ingo Schäfer, Carsten Kneuer, Peter Seibel, Walther Honscha. Assessment of ABCG2-mediated transport of pesticides across the rabbit placenta barrier using a novel MDCKII in vitro model.
Toxicology and applied pharmacology.
2016 08; 305(?):66-74. doi:
10.1016/j.taap.2016.06.007. [PMID: 27288731] - Manel Jallouli, Ines El Bini Dhouib, Hanène Dhouib, Montassar Lasram, Najoua Gharbi, Saloua El Fazaa. Disruption of steroidogenesis after dimethoate exposure and efficacy of N-acetylcysteine in rats: an old drug with new approaches.
Environmental science and pollution research international.
2016 Apr; 23(8):7975-84. doi:
10.1007/s11356-016-6070-1. [PMID: 26769589] - April Van Scoy, Ashley Pennell, Xuyang Zhang. Environmental Fate and Toxicology of Dimethoate.
Reviews of environmental contamination and toxicology.
2016; 237(?):53-70. doi:
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Regulatory toxicology and pharmacology : RTP.
2015 Dec; 73(3):853-8. doi:
10.1016/j.yrtph.2015.10.010. [PMID: 26482405] - Jitendra Kumar Pandey, Gunjan Dubey, R Gopal. Study the effect of insecticide dimethoate on photosynthetic pigments and photosynthetic activity of pigeon pea: Laser-induced chlorophyll fluorescence spectroscopy.
Journal of photochemistry and photobiology. B, Biology.
2015 Oct; 151(?):297-305. doi:
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Journal of agricultural and food chemistry.
2015 Sep; 63(37):8292-8. doi:
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Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.
2015; 50(9):958-70. doi:
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The Science of the total environment.
2015 Jan; 502(?):91-102. doi:
10.1016/j.scitotenv.2014.08.062. [PMID: 25241210] - Vijay Pratap Singh, Jitendra Kumar, Samiksha Singh, Sheo Mohan Prasad. Dimethoate modifies enhanced UV-B effects on growth, photosynthesis and oxidative stress in mung bean (Vigna radiata L.) seedlings: implication of salicylic acid.
Pesticide biochemistry and physiology.
2014 Nov; 116(?):13-23. doi:
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Ecotoxicology (London, England).
2014 Sep; 23(7):1220-33. doi:
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Neurotoxicity research.
2014 Apr; 25(3):271-85. doi:
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Pakistan journal of biological sciences : PJBS.
2014 Apr; 17(4):504-10. doi:
10.3923/pjbs.2014.504.510. [PMID: 25911837] - You-Hui Gong, Xin-Rui Yu, Qing-Li Shang, Xue-Yan Shi, Xi-Wu Gao. Oral delivery mediated RNA interference of a carboxylesterase gene results in reduced resistance to organophosphorus insecticides in the cotton Aphid, Aphis gossypii Glover.
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