L-Cystine (BioDeep_00000403028)

Main id: BioDeep_00000398127

 

natural product BioNovoGene_Lab2019


代谢物信息卡片


DL-Cystine

化学式: C6H12N2O4S2 (240.0238)
中文名称: DL-胱氨酸, L-胱氨酸, 胱氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(C(=O)O)N)SSCC(C(=O)O)N
InChI: InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)

描述信息

The L-enantiomer of the sulfur-containing amino acid cystine.

同义名列表

6 个代谢物同义名

L-Cystine; DL-Cystine; Cystine; L-Cystine; Cystine; L-cystine



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

114 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, ATF4, CAT, CBS, EGFR, PKM, SLC9A1, TXN, VEGFA
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 2 EGFR, SLC7A11
Nucleus 7 ALB, ATF4, CBS, EGFR, PKM, TXN, VEGFA
cytosol 9 ALB, ATF4, CAT, CBS, CYS1, GCLM, NGF, PKM, TXN
dendrite 1 NGF
centrosome 2 ALB, ATF4
nucleoplasm 4 ATF4, SLC3A2, SLC9A1, TXN
RNA polymerase II transcription regulator complex 1 ATF4
Cell membrane 9 ATF4, EGFR, SLC1A2, SLC3A1, SLC3A2, SLC7A11, SLC7A9, SLC9A1, TNF
Lipid-anchor 1 CYS1
lamellipodium 1 SLC9A1
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 4 SLC1A2, SLC7A11, SLC7A9, SLC9A1
Synapse 1 SLC3A2
cell junction 2 EGFR, SLC3A2
cell surface 7 EGFR, SLC1A2, SLC3A2, SLC7A11, SLC9A1, TNF, VEGFA
glutamatergic synapse 2 EGFR, SLC1A2
Golgi apparatus 2 ALB, VEGFA
Golgi membrane 2 EGFR, INS
lysosomal membrane 1 SLC3A2
neuronal cell body 1 TNF
presynaptic membrane 1 SLC1A2
synaptic vesicle 1 NGF
endosome 1 EGFR
plasma membrane 8 EGFR, SLC1A2, SLC3A1, SLC3A2, SLC7A11, SLC7A9, SLC9A1, TNF
Membrane 8 CAT, EGFR, SLC1A2, SLC3A1, SLC3A2, SLC7A11, SLC9A1, VEGFA
apical plasma membrane 5 EGFR, SLC3A1, SLC3A2, SLC7A9, SLC9A1
axon 1 NGF
basolateral plasma membrane 4 EGFR, SLC3A2, SLC7A11, SLC9A1
extracellular exosome 8 ALB, CAT, PKM, SLC3A1, SLC3A2, SLC9A1, TXN, VWF
Lysosome membrane 1 SLC3A2
endoplasmic reticulum 3 ALB, VEGFA, VWF
extracellular space 7 ALB, EGFR, INS, NGF, TNF, VEGFA, VWF
perinuclear region of cytoplasm 2 EGFR, SLC9A1
adherens junction 1 VEGFA
intercalated disc 1 SLC9A1
mitochondrion 3 CAT, PKM, SLC9A1
protein-containing complex 4 ALB, ATF4, CAT, EGFR
intracellular membrane-bounded organelle 1 CAT
Single-pass type I membrane protein 2 EGFR, SLC7A11
Secreted 6 ALB, INS, NGF, TXN, VEGFA, VWF
extracellular region 9 ALB, CAT, INS, NGF, PKM, TNF, TXN, VEGFA, VWF
mitochondrial matrix 1 CAT
anchoring junction 2 ALB, SLC3A2
ciliary membrane 1 CYS1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 ATF4
nuclear membrane 1 EGFR
external side of plasma membrane 1 TNF
Extracellular vesicle 1 PKM
Secreted, extracellular space, extracellular matrix 2 VEGFA, VWF
T-tubule 1 SLC9A1
apical part of cell 1 SLC7A11
recycling endosome 1 TNF
Single-pass type II membrane protein 3 SLC3A1, SLC3A2, TNF
vesicle 2 PKM, SLC1A2
Apical cell membrane 3 SLC3A1, SLC3A2, SLC7A9
Membrane raft 4 EGFR, SLC1A2, SLC9A1, TNF
focal adhesion 3 CAT, EGFR, SLC9A1
axolemma 1 SLC1A2
extracellular matrix 2 VEGFA, VWF
Peroxisome 1 CAT
intracellular vesicle 1 EGFR
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 2 PKM, VWF
secretory granule 1 VEGFA
lateral plasma membrane 1 SLC7A11
nuclear speck 1 ATF4
receptor complex 1 EGFR
neuron projection 1 ATF4
ciliary basal body 1 ALB
cilium 2 CYS1, PKM
chromatin 1 ATF4
phagocytic cup 1 TNF
cytoskeleton 1 CYS1
centriole 1 ALB
brush border membrane 3 SLC3A1, SLC7A11, SLC7A9
spindle pole 1 ALB
blood microparticle 1 ALB
Cytoplasm, cytoskeleton, cilium axoneme 1 CYS1
Basolateral cell membrane 3 SLC3A2, SLC7A11, SLC9A1
Cell projection, microvillus membrane 1 SLC7A11
microvillus membrane 1 SLC7A11
endosome lumen 2 INS, NGF
Melanosome 1 SLC3A2
Nucleus speckle 1 ATF4
cell body 1 SLC1A2
basal plasma membrane 2 EGFR, SLC3A2
synaptic membrane 1 EGFR
platelet alpha granule 1 VWF
ficolin-1-rich granule lumen 2 CAT, PKM
secretory granule lumen 3 CAT, INS, PKM
Golgi lumen 2 INS, NGF
endoplasmic reticulum lumen 2 ALB, INS
platelet alpha granule lumen 3 ALB, VEGFA, VWF
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 EGFR
dendrite membrane 1 ATF4
Rough endoplasmic reticulum 1 PKM
Cell projection, cilium membrane 1 CYS1
nuclear periphery 1 ATF4
astrocyte projection 2 SLC1A2, SLC7A11
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
Weibel-Palade body 1 VWF
vacuolar membrane 1 SLC3A1
amino acid transport complex 1 SLC3A2
apical pole of neuron 1 SLC3A2
neuron projection terminus 1 SLC1A2
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
ATF4-CREB1 transcription factor complex 1 ATF4
ATF1-ATF4 transcription factor complex 1 ATF4
CHOP-ATF4 complex 1 ATF4
Lewy body core 1 ATF4
cation-transporting ATPase complex 1 SLC9A1
membrane protein complex 1 SLC1A2
glutamate-cysteine ligase complex 1 GCLM
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Zhuoqun Li, Lixing Cao, Kai Han, Lihong Fan, Chong Zhao, Shutao Yin, Hongbo Hu. Non-cytotoxic nanomolar concentration of arctigenin protects neuronal cells from chemotherapy-induced ferroptosis by regulating SLC7A11-cystine-cysteine axis. Biochemical and biophysical research communications. 2024 May; 710(?):149895. doi: 10.1016/j.bbrc.2024.149895. [PMID: 38593620]
  • Lin Zhang, Wen-Yao Shi, Jia-Ying Xu, Yan Liu, Shi-Jia Wang, Jia-Yang Zheng, Yun-Hong Li, Lin-Xi Yuan, Li-Qiang Qin. Protective effects and mechanism of chemical- and plant-based selenocystine against cadmium-induced liver damage. Journal of hazardous materials. 2024 Apr; 468(?):133812. doi: 10.1016/j.jhazmat.2024.133812. [PMID: 38368684]
  • Chenfeng Han, Minmin Ge, Pengfei Xing, Tian Xia, Cangang Zhang, Kaili Ma, Yifu Ma, Shicheng Li, Wenhui Li, Xiaowei Liu, Baojun Zhang, Liyuan Zhang, Lianjun Zhang. Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells. Cell death & disease. 2024 Feb; 15(2):145. doi: 10.1038/s41419-024-06503-1. [PMID: 38360744]
  • Zhangjie Wang, Yang Wang, Na Shen, Yu Liu, Xinyang Xu, Ruiqiu Zhu, Hao Jiang, Xiaoting Wu, Yunfei Wei, Jingyuan Tang. AMPKα1-mediated ZDHHC8 phosphorylation promotes the palmitoylation of SLC7A11 to facilitate ferroptosis resistance in glioblastoma. Cancer letters. 2024 Jan; 584(?):216619. doi: 10.1016/j.canlet.2024.216619. [PMID: 38211651]
  • Shreya Banerjee, Rakesh Sarkar, Arpita Mukherjee, Suvrotoa Mitra, Animesh Gope, Mamta Chawla-Sarkar. Rotavirus-induced lncRNA SLC7A11-AS1 promotes ferroptosis by targeting cystine/glutamate antiporter xCT (SLC7A11) to facilitate virus infection. Virus research. 2024 01; 339(?):199261. doi: 10.1016/j.virusres.2023.199261. [PMID: 37923170]
  • Yuhe Wang, Xu Han, Jingru Shi, Zeqi Liao, Yuanyue Zhang, Yuanyuan Li, Miao Jiang, Meijie Liu. Distinct Metabolites in Osteopenia and Osteoporosis: A Systematic Review and Meta-Analysis. Nutrients. 2023 Nov; 15(23):. doi: 10.3390/nu15234895. [PMID: 38068753]
  • Yuki Kojima, Mamoru Tanaka, Makiko Sasaki, Keiji Ozeki, Takaya Shimura, Eiji Kubota, Hiromi Kataoka. Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers. Journal of gastroenterology. 2023 Nov; ?(?):. doi: 10.1007/s00535-023-02054-y. [PMID: 37947872]
  • Hai-Hua Wang, Song-Qing Fan, Yu-Ting Zhan, Shu-Ping Peng, Wei-Yuan Wang. Suppression of the SLC7A11/glutathione axis causes ferroptosis and apoptosis and alters the mitogen-activated protein kinase pathway in nasopharyngeal carcinoma. International journal of biological macromolecules. 2023 Nov; ?(?):127976. doi: 10.1016/j.ijbiomac.2023.127976. [PMID: 37951442]
  • Yueyang Liang, Lei Xia, Shuang Lu, Songru Yang, Shuting Guo, Xiaoli Shan, Pei Zhao, Chen Zhang, Wei Guo, Ming Xu, Huihua Chen, Rong Lu. A new mechanism of therapeutic effect of stachydrine on heart failure by inhibiting myocardial ferroptosis. European journal of pharmacology. 2023 Sep; 954(?):175881. doi: 10.1016/j.ejphar.2023.175881. [PMID: 37385579]
  • Shuquan Lv, Huajun Li, Tianyu Zhang, Xiuhai Su, Wenjuan Sun, Qinghai Wang, Lixin Wang, Nana Feng, Shufang Zhang, Yuansong Wang, Huantian Cui. San-Huang-Yi-Shen capsule ameliorates diabetic nephropathy in mice through inhibiting ferroptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Sep; 165(?):115086. doi: 10.1016/j.biopha.2023.115086. [PMID: 37418978]
  • Zuli Wang, Lianlian Ouyang, Na Liu, Tiansheng Li, Bokang Yan, Chao Mao, Desheng Xiao, Boyi Gan, Shuang Liu, Yongguang Tao. The DUBA-SLC7A11-c-Myc axis is critical for stemness and ferroptosis. Oncogene. 2023 09; 42(36):2688-2700. doi: 10.1038/s41388-023-02744-0. [PMID: 37537342]
  • Miyeon Kim, Ju Young Bae, Soyeon Yoo, Hyun Woo Kim, Sang Ah Lee, Eui Tae Kim, Gwanpyo Koh. 2-Deoxy-d-ribose induces ferroptosis in renal tubular epithelial cells via ubiquitin-proteasome system-mediated xCT protein degradation. Free radical biology & medicine. 2023 Sep; 208(?):384-393. doi: 10.1016/j.freeradbiomed.2023.08.027. [PMID: 37659699]
  • Junko Asakura, Manabu Nagao, Masakazu Shinohara, Makoto Nishimori, Sachiko Yoshikawa, Takuya Iino, Yutaro Seto, Hidekazu Tanaka, Seimi Satomi-Kobayashi, Tatsuro Ishida, Ken-Ichi Hirata, Ryuji Toh. Plasma cystine/methionine ratio is associated with left ventricular diastolic function in patients with heart disease. Heart and vessels. 2023 Aug; ?(?):. doi: 10.1007/s00380-023-02302-4. [PMID: 37620665]
  • Weitang Guo, Xin Wang, Bing Lu, Jiaming Yu, Mingxian Xu, Renxuan Huang, Mingzhe Cheng, Meiling Yang, Wei Zhao, Changye Zou. Super-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcoma. Cell death & disease. 2023 07; 14(7):439. doi: 10.1038/s41419-023-05966-y. [PMID: 37460542]
  • Sapna Lonare, Monica Sharma, Vikram Dalal, Mrugendra Gubyad, Pranav Kumar, Deena Nath Gupta, Akshay Pareek, Shailly Tomar, Dilip Kumar Ghosh, Pravindra Kumar, Ashwani Kumar Sharma. Identification and evaluation of potential inhibitor molecules against TcyA from Candidatus Liberibacter asiaticus. Journal of structural biology. 2023 Jun; 215(3):107992. doi: 10.1016/j.jsb.2023.107992. [PMID: 37394197]
  • Rafael Rosell, Anisha Jain, Jordi Codony-Servat, Eloisa Jantus-Lewintre, Blake Morrison, Jordi Barretina Ginesta, María González-Cao. Biological insights in non-small cell lung cancer. Cancer biology & medicine. 2023 Jun; ?(?):. doi: 10.20892/j.issn.2095-3941.2023.0108. [PMID: 37381723]
  • Zhixin Ma, Wenle Ye, Jinghan Wang, Xin Huang, Jiansong Huang, Xia Li, Chao Hu, Chenying Li, Yile Zhou, Xiangjie Lin, Wenwen Wei, Yu Qian, Yutong Zhou, Shihui Mao, Xiufeng Yin, Bo Zhu, Jie Jin. Glutamate dehydrogenase 1: A novel metabolic target in inhibiting acute myeloid leukaemia progression. British journal of haematology. 2023 May; ?(?):. doi: 10.1111/bjh.18884. [PMID: 37231991]
  • Feng He, Peng Zhang, Junlai Liu, Ruolei Wang, Randal J Kaufman, Benjamin C Yaden, Michael Karin. ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis. Journal of hepatology. 2023 Mar; ?(?):. doi: 10.1016/j.jhep.2023.03.016. [PMID: 36996941]
  • Xiaorui Wang, Lei Zhao, Chenxi Wang, Leichen Wang, Haisi Wu, Xuejiao Song, Wenjun Wang, Huae Xu, Xiaochen Dong. Potent nanoreactor-mediated ferroptosis-based strategy for the reversal of cancer chemoresistance to Sorafenib. Acta biomaterialia. 2023 Feb; ?(?):. doi: 10.1016/j.actbio.2023.01.053. [PMID: 36736851]
  • Qing Tong, Wei Qin, Zheng-Hao Li, Chun Liu, Zi-Cheng Wang, Yuan Chu, Xun-Di Xu. SLC12A5 promotes hepatocellular carcinoma growth and ferroptosis resistance by inducing ER stress and cystine transport changes. Cancer medicine. 2023 Jan; ?(?):. doi: 10.1002/cam4.5605. [PMID: 36645171]
  • Patrick Willems, Jingjing Huang, Joris Messens, Frank Van Breusegem. Functionally annotating cysteine disulfides and metal binding sites in the plant kingdom using AlphaFold2 predicted structures. Free radical biology & medicine. 2023 01; 194(?):220-229. doi: 10.1016/j.freeradbiomed.2022.12.001. [PMID: 36493985]
  • Rehman Sarwar, Lei Li, Jiang Yu, Yijie Zhang, Rui Geng, Qingfeng Meng, Keming Zhu, Xiao-Li Tan. Functional Characterization of the Cystine-Rich-Receptor-like Kinases (CRKs) and Their Expression Response to Sclerotinia sclerotiorum and Abiotic Stresses in Brassica napus. International journal of molecular sciences. 2022 Dec; 24(1):. doi: 10.3390/ijms24010511. [PMID: 36613954]
  • Amany Elshorbagy, Nasser E Bastani, Sindre Lee-Ødegård, Bente Øvrebø, Nadia Haj-Yasein, Karianne Svendsen, Cheryl Turner, Helga Refsum, Kathrine J Vinknes, Thomas Olsen. The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression. Amino acids. 2022 Dec; ?(?):. doi: 10.1007/s00726-022-03229-2. [PMID: 36542145]
  • Minako Oda, Kousuke Fujibayashi, Minoru Wakasa, Shintaro Takano, Wataru Fujita, Michihiko Kitayama, Hiroaki Nakanishi, Kazuyuki Saito, Yasuyuki Kawai, Kouji Kajinami. Increased plasma glutamate in non-smokers with vasospastic angina pectoris is associated with plasma cystine and antioxidant capacity. Scandinavian cardiovascular journal : SCJ. 2022 12; 56(1):180-186. doi: 10.1080/14017431.2022.2085884. [PMID: 35695518]
  • Nibin Shi, Xin Yan, Adeyemi S Adeleye, Xuxiang Zhang, Dongmei Zhou, Lijuan Zhao. Effects of WS2 Nanosheets on N2-fixing Cyanobacteria: ROS overproduction, cell membrane damage, and cell metabolic reprogramming. The Science of the total environment. 2022 Nov; 849(?):157706. doi: 10.1016/j.scitotenv.2022.157706. [PMID: 35908696]
  • Yetong Feng, Jiayi Xu, Mengjiao Shi, Rongrong Liu, Lei Zhao, Xin Chen, Miaomiao Li, Yaping Zhao, Jiahui Chen, Wenjing Du, Pengfei Liu. COX7A1 enhances the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via regulating mitochondrial metabolism. Cell death & disease. 2022 11; 13(11):988. doi: 10.1038/s41419-022-05430-3. [PMID: 36418320]
  • David A Armenta, Nouf N Laqtom, Grace Alchemy, Wentao Dong, Danielle Morrow, Carson D Poltorack, David A Nathanson, Monther Abu-Remalieh, Scott J Dixon. Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein. Cell chemical biology. 2022 11; 29(11):1588-1600.e7. doi: 10.1016/j.chembiol.2022.10.006. [PMID: 36306785]
  • Takujiro Homma, Yuki Nishino, Junichi Fujii, Chikako Yokoyama. Flow cytometric determination of ferroptosis using a rat monoclonal antibody raised against ferroptotic cells. Journal of immunological methods. 2022 11; 510(?):113358. doi: 10.1016/j.jim.2022.113358. [PMID: 36126779]
  • Mohammad K Okla, S Balasurya, Ibrahim A Alaraidh, Asmaa Mohebaldin, Abdullah A Al-Ghamdi, Mohammed A Al-Okla, Mostafa A Abdel-Maksoud, Ramadan F Abdelaziz, Walid Soufan, R Balakrishnaraja, Lija L Raju, Ajith M Thomas, S Sudheer Khan. Plasma-assisted in-situ preparation of L-cystine functionalized silver nanoparticle: An intelligent multicolor nano-sensing of cadmium and paracetamol from environmental sample. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2022 Oct; 279(?):121330. doi: 10.1016/j.saa.2022.121330. [PMID: 35605418]
  • Zihan Zhang, Rui Zheng, Caihua Zhu, Hongquan Geng, Guofeng Xu. Lipidomics characterization of the lipid metabolism profiles in a cystinuria rat model: Precalculus damage in the kidney of cystinuria. Prostaglandins & other lipid mediators. 2022 10; 162(?):106651. doi: 10.1016/j.prostaglandins.2022.106651. [PMID: 35680078]
  • David Matye, Sumedha Gunewardena, Jianglei Chen, Huaiwen Wang, Yifeng Wang, Mohammad Nazmul Hasan, Lijie Gu, Yung Dai Clayton, Yanhong Du, Cheng Chen, Jacob E Friedman, Shelly C Lu, Wen-Xing Ding, Tiangang Li. TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis. Nature communications. 2022 09; 13(1):5696. doi: 10.1038/s41467-022-33465-9. [PMID: 36171419]
  • Chao-Yuan Huang, Li-Ju Chen, Grace Chen, Tzu-I Chao, Cheng-Yi Wang. SHP-1/STAT3-Signaling-Axis-Regulated Coupling between BECN1 and SLC7A11 Contributes to Sorafenib-Induced Ferroptosis in Hepatocellular Carcinoma. International journal of molecular sciences. 2022 Sep; 23(19):. doi: 10.3390/ijms231911092. [PMID: 36232407]
  • Ling Gao, Qiang Gu, Hong Wang, Xingkong Ma, Feng Xue, Xing Zhang, Jiachun Ge, Tao Ding, Weijian Shen. [Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry]. Se pu = Chinese journal of chromatography. 2022 Sep; 40(9):825-832. doi: 10.3724/sp.j.1123.2022.03027. [PMID: 36156629]
  • Jennifer A Hollywood, Prasanna K Kallingappa, Pang Yuk Cheung, Renita M Martis, Sree Sreebhavan, Robert D 'Atiola, Aparajita Chatterjee, Emma J Buckels, Brya G Matthews, Paula M Lewis, Alan J Davidson. Cystinosin-deficient rats recapitulate the phenotype of nephropathic cystinosis. American journal of physiology. Renal physiology. 2022 08; 323(2):F156-F170. doi: 10.1152/ajprenal.00277.2021. [PMID: 35695380]
  • Viola D'Ambrosio, Giovanna Capolongo, David Goldfarb, Giovanni Gambaro, Pietro Manuel Ferraro. Cystinuria: an update on pathophysiology, genetics, and clinical management. Pediatric nephrology (Berlin, Germany). 2022 08; 37(8):1705-1711. doi: 10.1007/s00467-021-05342-y. [PMID: 34812923]
  • Yusei Tataka, Miki Haramura, Yuka Hamada, Miho Ono, Sakiko Toyoda, Toshiyuki Yamada, Ayano Hiratsu, Katsuhiko Suzuki, Masashi Miyashita. Effects of oral cystine and glutamine on exercise-induced changes in gastrointestinal permeability and damage markers in young men. European journal of nutrition. 2022 Aug; 61(5):2331-2339. doi: 10.1007/s00394-022-02806-1. [PMID: 35106632]
  • Hui Chen, Lixing Cao, Kai Han, Han Zhang, Jinling Cui, Xuan Ma, Shuang Zhao, Chong Zhao, Shutao Yin, Lihong Fan, Hongbo Hu. Patulin disrupts SLC7A11-cystine-cysteine-GSH antioxidant system and promotes renal cell ferroptosis both in vitro and in vivo. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Aug; 166(?):113255. doi: 10.1016/j.fct.2022.113255. [PMID: 35772596]
  • Shuichi Okamoto, Shogo Tamura, Naomi Sanda, Koya Odaira, Yuri Hayakawa, Masato Mukaide, Atsuo Suzuki, Takeshi Kanematsu, Fumihiko Hayakawa, Akira Katsumi, Hitoshi Kiyoi, Tetsuhito Kojima, Tadashi Matsushita, Nobuaki Suzuki. VWF-Gly2752Ser, a novel non-cysteine substitution variant in the CK domain, exhibits severe secretory impairment by hampering C-terminal dimer formation. Journal of thrombosis and haemostasis : JTH. 2022 08; 20(8):1784-1796. doi: 10.1111/jth.15746. [PMID: 35491445]
  • Patrick Krohn, Laura Rita Rega, Marianne Harvent, Beatrice Paola Festa, Anna Taranta, Alessandro Luciani, Joseph Dewulf, Alessio Cremonesi, Francesca Diomedi Camassei, James V M Hanson, Christina Gerth-Kahlert, Francesco Emma, Marine Berquez, Olivier Devuyst. Multisystem involvement, defective lysosomes and impaired autophagy in a novel rat model of nephropathic cystinosis. Human molecular genetics. 2022 Jul; 31(13):2262-2278. doi: 10.1093/hmg/ddac033. [PMID: 35137071]
  • Guangming He, Keling Chen, Hao Wang, Xiaoou Li, Wenhao Li, Lian Liu, Jun Chen, Deqing Yang, Jun Hu, Dan Xu, Fuqiang Wen, Tao Wang. Fudosteine attenuates acute lung injury in septic mice by inhibiting pyroptosis via the TXNIP/NLRP3/GSDMD pathway. European journal of pharmacology. 2022 Jul; 926(?):175047. doi: 10.1016/j.ejphar.2022.175047. [PMID: 35609679]
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