3-Hydroxykynurenine (BioDeep_00000399989)

Main id: BioDeep_00000001751

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


3-hydroxy-dl-kynurenine

化学式: C10H12N2O4 (224.0797)
中文名称: 3-羟基-DL-犬尿素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C(=C1)O)N)C(=O)CC(C(=O)O)N
InChI: InChI=1S/C10H12N2O4/c11-6(10(15)16)4-8(14)5-2-1-3-7(13)9(5)12/h1-3,6,13H,4,11-12H2,(H,15,16)

描述信息

A hydroxykynurenine that is kynurenine substituted by a hydroxy group at position 3.
C26170 - Protective Agent > C275 - Antioxidant
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; VCKPUUFAIGNJHC-UHFFFAOYSA-N_STSL_0007_3-Hydroxy-DL-Kynurenine_8000fmol_180416_S2_LC02_MS02_13; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.

同义名列表

3 个代谢物同义名

3-hydroxy-dl-kynurenine; 3-Hydroxykynurenine; 3-Hydroxykynurenine



数据库引用编号

35 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 BDNF, CASP3, CAT, HTT, IDO1, KYNU, QPRT, TYR, XDH
Endosome membrane 1 HTT
Endoplasmic reticulum membrane 1 CD4
Nucleus 2 CASP3, HTT
autophagosome 1 HTT
cytosol 9 CASP3, CAT, HTT, IDO1, KMO, KYNU, QPRT, TDO2, XDH
dendrite 2 BDNF, HTT
nucleoplasm 3 CASP3, HTT, KYNU
Cell membrane 3 CD4, HTT, TNF
Multi-pass membrane protein 2 HTT, KMO
Synapse 1 HTT
cell surface 1 TNF
glutamatergic synapse 1 CASP3
Golgi apparatus 1 HTT
Golgi membrane 1 INS
neuronal cell body 2 CASP3, TNF
presynaptic membrane 1 HTT
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 2 IDO1, KYNU
Lysosome 1 TYR
plasma membrane 4 CD4, HTT, IFNLR1, TNF
Membrane 4 BDNF, CAT, IFNLR1, KMO
axon 2 BDNF, HTT
extracellular exosome 2 CAT, QPRT
endoplasmic reticulum 1 HTT
extracellular space 9 BDNF, CRP, IFNG, IL10, IL6, INS, KMO, TNF, XDH
perinuclear region of cytoplasm 3 BDNF, HTT, TYR
mitochondrion 4 AADAT, CAT, KMO, KYNU
protein-containing complex 2 CAT, HTT
intracellular membrane-bounded organelle 2 CAT, TYR
postsynaptic density 1 CASP3
Single-pass type I membrane protein 3 CD4, IFNLR1, TYR
Secreted 6 BDNF, CRP, IFNG, IL10, IL6, INS
extracellular region 8 BDNF, CAT, CRP, IFNG, IL10, IL6, INS, TNF
Mitochondrion outer membrane 1 KMO
mitochondrial outer membrane 1 KMO
mitochondrial matrix 2 AADAT, CAT
external side of plasma membrane 2 CD4, TNF
Melanosome membrane 1 TYR
Early endosome 2 CD4, HTT
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 1 HTT
Membrane raft 3 CD4, HTT, TNF
Cell junction, focal adhesion 1 HTT
focal adhesion 2 CAT, HTT
Peroxisome 2 CAT, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Late endosome 1 HTT
Cell projection, neuron projection 1 HTT
neuron projection 1 HTT
stereocilium bundle 1 IDO1
phagocytic cup 1 TNF
centriole 1 HTT
Endomembrane system 1 HTT
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 HTT
Melanosome 1 TYR
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 BDNF, CD4, IL6, INS
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 CD4
death-inducing signaling complex 1 CASP3
postsynaptic cytosol 1 HTT
presynaptic cytosol 1 HTT
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
catalase complex 1 CAT
inclusion body 1 HTT
catalytic complex 1 QPRT
interleukin-6 receptor complex 1 IL6
smooth muscle contractile fiber 1 IDO1
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
serotonergic synapse 1 HTT
[Huntingtin]: Cytoplasm 1 HTT
[Huntingtin, myristoylated N-terminal fragment]: Cytoplasmic vesicle, autophagosome 1 HTT
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Aleksandr V Zhuravlev, Boris F Shchegolev, Gennadii A Zakharov, Polina N Ivanova, Ekaterina A Nikitina, Elena V Savvateeva-Popova. 3-Hydroxykynurenine as a Potential Ligand for Hsp70 Proteins and Its Effects on Drosophila Memory After Heat Shock. Molecular neurobiology. 2022 Mar; 59(3):1862-1871. doi: 10.1007/s12035-021-02704-3. [PMID: 35029786]
  • Laura Ansone, Monta Briviba, Ivars Silamikelis, Anna Terentjeva, Ingus Perkons, Liga Birzniece, Vita Rovite, Baiba Rozentale, Ludmila Viksna, Oksana Kolesova, Kristaps Klavins, Janis Klovins. Amino Acid Metabolism is Significantly Altered at the Time of Admission in Hospital for Severe COVID-19 Patients: Findings from Longitudinal Targeted Metabolomics Analysis. Microbiology spectrum. 2021 12; 9(3):e0033821. doi: 10.1128/spectrum.00338-21. [PMID: 34878333]
  • Lieke Bakker, Inez H G B Ramakers, Martin P J van Boxtel, Miranda T Schram, Coen D A Stehouwer, Carla J H van der Kallen, Pieter C Dagnelie, Marleen M J van Greevenbroek, Anke Wesselius, Øivind Midttun, Per M Ueland, Frans R J Verhey, Simone J P M Eussen, Sebastian Köhler. Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study. Diabetologia. 2021 11; 64(11):2445-2457. doi: 10.1007/s00125-021-05521-4. [PMID: 34409496]
  • Cristina C Clement, Angelo D'Alessandro, Sangeetha Thangaswamy, Samantha Chalmers, Raquel Furtado, Sheila Spada, Giada Mondanelli, Federica Ianni, Sarah Gehrke, Marco Gargaro, Giorgia Manni, Luisa Carlota Lopez Cara, Peter Runge, Wanxia Li Tsai, Sinem Karaman, Jorge Arasa, Ruben Fernandez-Rodriguez, Amanda Beck, Antonio Macchiarulo, Massimo Gadina, Cornelia Halin, Francesca Fallarino, Mihaela Skobe, Marc Veldhoen, Simone Moretti, Silvia Formenti, Sandra Demaria, Rajesh K Soni, Roberta Galarini, Roccaldo Sardella, Gregoire Lauvau, Chaim Putterman, Kari Alitalo, Ursula Grohmann, Laura Santambrogio. 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine. Nature communications. 2021 07; 12(1):4447. doi: 10.1038/s41467-021-24785-3. [PMID: 34290243]
  • Ewa Dudzińska, Kinga Szymona, Renata Kloc, Tomasz Kocki, Paulina Gil-Kulik, Jacek Bogucki, Janusz Kocki, Roman Paduch, Ewa M Urbańska. Fractalkine, sICAM-1 and Kynurenine Pathway in Restrictive Anorexia Nervosa-Exploratory Study. Nutrients. 2021 Jan; 13(2):. doi: 10.3390/nu13020339. [PMID: 33498837]
  • Michal Fiedorowicz, Tomasz Choragiewicz, Waldemar A Turski, Tomasz Kocki, Dominika Nowakowska, Kamila Wertejuk, Agnieszka Kamińska, Teresio Avitabile, Marlena Wełniak-Kaminska, Pawel Grieb, Sandrine Zweifel, Robert Rejdak, Mario Damiano Toro. Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma. International journal of molecular sciences. 2021 Jan; 22(3):. doi: 10.3390/ijms22031039. [PMID: 33494373]
  • Paul Carrillo-Mora, Verónica Pérez-De la Cruz, Berenice Estrada-Cortés, Paola Toussaint-González, José Antonio Martínez-Cortéz, Marlene Rodríguez-Barragán, Jimena Quinzaños-Fresnedo, Fernanda Rangel-Caballero, Gabriela Gamboa-Coria, Itzel Sánchez-Vázquez, Karina Barajas-Martínez, Kenia Franyutti-Prado, Laura Sánchez-Chapul, Daniela Ramírez-Ortega, Lucio A Ramos-Chávez. Serum Kynurenines Correlate With Depressive Symptoms and Disability in Poststroke Patients: A Cross-sectional Study. Neurorehabilitation and neural repair. 2020 10; 34(10):936-944. doi: 10.1177/1545968320953671. [PMID: 32917127]
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  • Gregory Oxenkrug, Hans-Gert Bernstein, Paul C Guest, Marieke van der Hart, Julien Roeser, Paul Summergrad, Johann Steiner. Plasma xanthurenic acid in a context of insulin resistance and obesity in schizophrenia. Schizophrenia research. 2019 09; 211(?):98-99. doi: 10.1016/j.schres.2019.07.038. [PMID: 31383514]
  • Jana Vondroušová, Miloš Mikoška, Kamila Syslová, Adéla Böhmová, Hana Tejkalová, Lukáš Vacek, Petr Kodym, Daniel Krsek, Jiří Horáček. Monitoring of kynurenine pathway metabolites, neurotransmitters and their metabolites in blood plasma and brain tissue of individuals with latent toxoplasmosis. Journal of pharmaceutical and biomedical analysis. 2019 Jun; 170(?):139-152. doi: 10.1016/j.jpba.2019.03.039. [PMID: 30925271]
  • Martina Curto, Luana Lionetto, Francesco Fazio, Valentina Corigliano, Anna Comparelli, Stefano Ferracuti, Maurizio Simmaco, Ferdinando Nicoletti, Ross J Baldessarini. Serum xanthurenic acid levels: Reduced in subjects at ultra high risk for psychosis. Schizophrenia research. 2019 06; 208(?):465-466. doi: 10.1016/j.schres.2019.02.020. [PMID: 30837204]
  • Jon Sigurd Sande, Arve Ulvik, Øivind Midttun, Per M Ueland, Hilde B Hammer, Merete Valen, Ellen M Apalset, Clara G Gjesdal. Vitamin B-6 Status Correlates with Disease Activity in Rheumatoid Arthritis Patients During Treatment with TNFα Inhibitors. The Journal of nutrition. 2019 05; 149(5):770-775. doi: 10.1093/jn/nxz001. [PMID: 31050750]
  • Livia De Picker, Erik Fransen, Violette Coppens, Maarten Timmers, Peter de Boer, Herbert Oberacher, Dietmar Fuchs, Robert Verkerk, Bernard Sabbe, Manuel Morrens. Immune and Neuroendocrine Trait and State Markers in Psychotic Illness: Decreased Kynurenines Marking Psychotic Exacerbations. Frontiers in immunology. 2019; 10(?):2971. doi: 10.3389/fimmu.2019.02971. [PMID: 32010121]
  • Zhenzhao Wang, Rui Xu, Guiping Shen, Jianghua Feng. Metabolic Response in Rabbit Urine to Occurrence and Relief of Unilateral Ureteral Obstruction. Journal of proteome research. 2018 09; 17(9):3184-3194. doi: 10.1021/acs.jproteome.8b00304. [PMID: 30024170]
  • Freek J H Sorgdrager, Jorien Werumeus Buning, Elske H Bos, André P Van Beek, Ido P Kema. Hydrocortisone Affects Fatigue and Physical Functioning Through Metabolism of Tryptophan: A Randomized Controlled Trial. The Journal of clinical endocrinology and metabolism. 2018 09; 103(9):3411-3419. doi: 10.1210/jc.2018-00582. [PMID: 29982583]
  • Joyce Y Huang, Lesley M Butler, Øivind Midttun, Arve Ulvik, Renwei Wang, Aizhen Jin, Yu-Tang Gao, Per M Ueland, Woon-Puay Koh, Jian-Min Yuan. A prospective evaluation of serum kynurenine metabolites and risk of pancreatic cancer. PloS one. 2018; 13(5):e0196465. doi: 10.1371/journal.pone.0196465. [PMID: 29734388]
  • Gertrud L Haverkamp, Wim L Loosman, Robbert W Schouten, Casper F Franssen, Ido P Kema, Merel van Diepen, Friedo W Dekker, Carl E Siegert, Adriaan Honig. Differences in the association of inflammation and tryptophan with depressive symptoms between white and non-white chronic dialysis patients. General hospital psychiatry. 2018 Jan; 50(?):76-82. doi: 10.1016/j.genhosppsych.2017.10.003. [PMID: 29065338]
  • Isidor Minović, Anna van der Veen, Martijn van Faassen, Ineke J Riphagen, Else van den Berg, Claude van der Ley, António W Gomes-Neto, Johanna M Geleijnse, Manfred Eggersdorfer, Gerjan J Navis, Ido P Kema, Stephan Jl Bakker. Functional vitamin B-6 status and long-term mortality in renal transplant recipients. The American journal of clinical nutrition. 2017 Dec; 106(6):1366-1374. doi: 10.3945/ajcn.117.164012. [PMID: 28978540]
  • Claudio Ferrante, Lucia Recinella, Marcello Locatelli, Paolo Guglielmi, Daniela Secci, Lidia Leporini, Annalisa Chiavaroli, Sheila Leone, Sara Martinotti, Luigi Brunetti, Michele Vacca, Luigi Menghini, Giustino Orlando. Protective Effects Induced by Microwave-Assisted Aqueous Harpagophytum Extract on Rat Cortex Synaptosomes Challenged with Amyloid β-Peptide. Phytotherapy research : PTR. 2017 Aug; 31(8):1257-1264. doi: 10.1002/ptr.5850. [PMID: 28635142]
  • Laura V de Vries, Isidor Minović, Casper F M Franssen, Martijn van Faassen, Jan-Stephan F Sanders, Stefan P Berger, Gerjan Navis, Ido P Kema, Stephan J L Bakker. The tryptophan/kynurenine pathway, systemic inflammation, and long-term outcome after kidney transplantation. American journal of physiology. Renal physiology. 2017 08; 313(2):F475-F486. doi: 10.1152/ajprenal.00690.2016. [PMID: 28490533]
  • Martina Platzer, Nina Dalkner, Frederike T Fellendorf, Armin Birner, Susanne A Bengesser, Robert Queissner, Nora Kainzbauer, René Pilz, Simone Herzog-Eberhard, Carlo Hamm, Christa Hörmanseder, Alexander Maget, Philipp Rauch, Harald Mangge, Dietmar Fuchs, Sieglinde Zelzer, Gregor Schütze, Natalie Moll, Markus J Schwarz, Rodrigo B Mansur, Roger S McIntyre, Eva Z Reininghaus. Tryptophan breakdown and cognition in bipolar disorder. Psychoneuroendocrinology. 2017 Jul; 81(?):144-150. doi: 10.1016/j.psyneuen.2017.04.015. [PMID: 28482311]
  • Sai-Ying Wang, Kai-Ming Duan, Xiao-Fang Tan, Ji-Ye Yin, Xiao-Yuan Mao, Wei Zheng, Chun-Yan Wang, Mi Yang, Cheng Peng, Hong-Hao Zhou, Zhao-Qian Liu. Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women. Journal of affective disorders. 2017 06; 215(?):94-101. doi: 10.1016/j.jad.2017.03.023. [PMID: 28319697]
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  • Björn Gylling, Robin Myte, Jörn Schneede, Göran Hallmans, Jenny Häggström, Ingegerd Johansson, Arve Ulvik, Per M Ueland, Bethany Van Guelpen, Richard Palmqvist. Vitamin B-6 and colorectal cancer risk: a prospective population-based study using 3 distinct plasma markers of vitamin B-6 status. The American journal of clinical nutrition. 2017 04; 105(4):897-904. doi: 10.3945/ajcn.116.139337. [PMID: 28275126]
  • Therese Karlsson, Elin Strand, Jutta Dierkes, Christian A Drevon, Jannike Øyen, Øivind Midttun, Per M Ueland, Oddrun A Gudbrandsen, Eva Ringdal Pedersen, Ottar Nygård. Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease. European journal of nutrition. 2017 Feb; 56(1):261-272. doi: 10.1007/s00394-015-1077-9. [PMID: 26482150]
  • Tomoyuki Tashiro, Yuki Murakami, Akihiro Mouri, Yukio Imamura, Toshitaka Nabeshima, Yasuko Yamamoto, Kuniaki Saito. Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions. Behavioural brain research. 2017 01; 317(?):279-285. doi: 10.1016/j.bbr.2016.09.050. [PMID: 27693848]
  • Nick Goeden, Francesca M Notarangelo, Ana Pocivavsek, Sarah Beggiato, Alexandre Bonnin, Robert Schwarcz. Prenatal Dynamics of Kynurenine Pathway Metabolism in Mice: Focus on Kynurenic Acid. Developmental neuroscience. 2017; 39(6):519-528. doi: 10.1159/000481168. [PMID: 29080891]
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  • Oana M Deac, James L Mills, Clair M Gardiner, Barry Shane, Louise Quinn, Øivind Midttun, Adrian McCann, Klaus Meyer, Per M Ueland, Ruzong Fan, Zhaohui Lu, Lawrence C Brody, Anne M Molloy. Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults. The Journal of nutrition. 2016 09; 146(9):1801-6. doi: 10.3945/jn.116.230698. [PMID: 27489009]
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  • Timothy B Meier, Jonathan Savitz, Rashmi Singh, T Kent Teague, Patrick S F Bellgowan. Smaller Dentate Gyrus and CA2 and CA3 Volumes Are Associated with Kynurenine Metabolites in Collegiate Football Athletes. Journal of neurotrauma. 2016 07; 33(14):1349-57. doi: 10.1089/neu.2015.4118. [PMID: 26493952]
  • Timothy B Meier, Wayne C Drevets, Brent E Wurfel, Bart N Ford, Harvey M Morris, Teresa A Victor, Jerzy Bodurka, T Kent Teague, Robert Dantzer, Jonathan Savitz. Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder. Brain, behavior, and immunity. 2016 Mar; 53(?):39-48. doi: 10.1016/j.bbi.2015.11.003. [PMID: 26546831]
  • Malgorzata Jasiewicz, Marcin Moniuszko, Dariusz Pawlak, Malgorzata Knapp, Malgorzata Rusak, Remigiusz Kazimierczyk, Wlodzimierz Jerzy Musial, Milena Dabrowska, Karol Adam Kaminski. Activity of the kynurenine pathway and its interplay with immunity in patients with pulmonary arterial hypertension. Heart (British Cardiac Society). 2016 Feb; 102(3):230-7. doi: 10.1136/heartjnl-2015-308581. [PMID: 26769378]
  • James Henry Obol, Denis Anywar Arony, Ronald Wanyama, Kenneth Luryama Moi, Bongomin Bodo, Patrick Olwedo Odong, Michael Odida. Reduced plasma concentrations of vitamin B6 and increased plasma concentrations of the neurotoxin 3-hydroxykynurenine are associated with nodding syndrome: a case control study in Gulu and Amuru districts, Northern Uganda. The Pan African medical journal. 2016; 24(?):123. doi: 10.11604/pamj.2016.24.123.8409. [PMID: 27642461]
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  • Luisa Rios-Avila, Bonnie Coats, Maria Ralat, Yueh-Yun Chi, Øivind Midttun, Per M Ueland, Peter W Stacpoole, Jesse F Gregory. Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users. The American journal of clinical nutrition. 2015 Sep; 102(3):616-25. doi: 10.3945/ajcn.115.113159. [PMID: 26201817]
  • Sinan Guloksuz, Baer Arts, Sharon Walter, Marjan Drukker, Laura Rodriguez, Aye-Mu Myint, Markus J Schwarz, Rudolf Ponds, Jim van Os, Gunter Kenis, Bart P F Rutten. The impact of electroconvulsive therapy on the tryptophan-kynurenine metabolic pathway. Brain, behavior, and immunity. 2015 Aug; 48(?):48-52. doi: 10.1016/j.bbi.2015.02.029. [PMID: 25765557]
  • Hui Zuo, Per M Ueland, Simone J P M Eussen, Grethe S Tell, Stein E Vollset, Ottar Nygård, Øivind Midttun, Klaus Meyer, Arve Ulvik. Markers of vitamin B6 status and metabolism as predictors of incident cancer: the Hordaland Health Study. International journal of cancer. 2015 Jun; 136(12):2932-9. doi: 10.1002/ijc.29345. [PMID: 25404109]
  • Oana M Deac, James L Mills, Barry Shane, Øivind Midttun, Per M Ueland, John T Brosnan, Margaret E Brosnan, Eamon Laird, Eileen R Gibney, Ruzong Fan, Yifan Wang, Lawrence C Brody, Anne M Molloy. Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults. The Journal of nutrition. 2015 Apr; 145(4):701-7. doi: 10.3945/jn.114.203091. [PMID: 25833774]
  • Martina Curto, Luana Lionetto, Andrea Negro, Matilde Capi, Francesca Perugino, Francesco Fazio, Maria Adele Giamberardino, Maurizio Simmaco, Ferdinando Nicoletti, Paolo Martelletti. Altered serum levels of kynurenine metabolites in patients affected by cluster headache. The journal of headache and pain. 2015; 17(?):27. doi: 10.1186/s10194-016-0620-2. [PMID: 27000870]
  • Luisa Rios-Avila, Bonnie Coats, Yueh-Yun Chi, Øivind Midttun, Per M Ueland, Peter W Stacpoole, Jesse F Gregory. Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives on these processes. The Journal of nutrition. 2015 Jan; 145(1):87-95. doi: 10.3945/jn.114.201095. [PMID: 25527663]
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