Vecuronium (BioDeep_00000398472)
Main id: BioDeep_00000003190
Secondary id: BioDeep_00001868276
代谢物信息卡片
化学式: [C34H57N2O4]+ (557.4318)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C([N+1]1(C(C2)C(C(C3)(C)C([H])2C(C6)([H])C(C(C4(C6)[H])(CC(N(C5)CCCC5)C(C4)OC(C)=O)C)([H])C3)OC(C)=O)C)CCCC1
InChI: InChI=1S/C34H57N2O4/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36/h25-32H,6-22H2,1-5H3/q+1/t25-,26+,27-,28-,29-,30-,31-,32-,33-,34-/m0/s1
描述信息
D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents > D009466 - Neuromuscular Blocking Agents
M - Musculo-skeletal system > M03 - Muscle relaxants > M03A - Muscle relaxants, peripherally acting agents
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists
同义名列表
1 个代谢物同义名
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:9939
- KEGG: C07553
- PubChem: 39765
- DrugBank: DB01339
- ChEMBL: CHEMBL1201219
- MeSH: Vecuronium Bromide
- CAS: 86029-43-8
- MoNA: WA001761
- MoNA: WA001760
- MoNA: WA001759
- MoNA: WA001758
- MoNA: CO000510
- MoNA: CO000509
- MoNA: CO000508
- MoNA: CO000507
- MoNA: CO000506
- PubChem: 9756
- NIKKAJI: J355.440F
- RefMet: Vecuronium
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Analía I Alet, Marcus V Batista da Silva, Horacio V Castellini, Nicolás A Alet, Bibiana D Riquelme. In vitro alteration on erythrocytes mechanical properties by propofol, remifentanil and vecuronium.
Microvascular research.
2021 05; 135(?):104132. doi:
10.1016/j.mvr.2021.104132
. [PMID: 33421433] - Kate Mostoller, Rebecca Wrishko, Lata Maganti, W Joseph Herring, Mariëlle van Zutphen-van Geffen. Pharmacokinetics of Sugammadex Dosed by Actual and Ideal Body Weight in Patients With Morbid Obesity Undergoing Surgery.
Clinical and translational science.
2021 03; 14(2):737-744. doi:
10.1111/cts.12941
. [PMID: 33278332] - YingYing Jiang, YuJun Zhang, ShunJu Xiang, WenLing Zhao, Jin Liu, WenSheng Zhang. Safety, tolerability, and pharmacokinetics of adamgammadex sodium, a novel agent to reverse the action of rocuronium and vecuronium, in healthy volunteers.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2020 Jan; 141(?):105134. doi:
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International journal of medical sciences.
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Anesthesiology.
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Masui. The Japanese journal of anesthesiology.
2013 Oct; 62(10):1225-9. doi:
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2011 Oct; 27(4):556-8. doi:
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2011 Sep; 60(9):835-40. doi:
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The Korean journal of pain.
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2011 Sep; 31(9):1181-6. doi:
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2011 Sep; 40(3):722-9. doi:
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2011 Jul; 49(1):16-9. doi:
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Korean journal of anesthesiology.
2011 Jul; 61(1):35-41. doi:
10.4097/kjae.2011.61.1.35
. [PMID: 21860749] - Marcel A H de Zwart, Jolanda ten Bruggencate-Broeders, Henk J M van Hal, René H J J J Megens, Helma W L H Frasa. Determination of sugammadex in human plasma, urine, and dialysate using a high-performance liquid chromatography/tandem mass spectrometry assay.
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2011 Jun; 879(19):1573-86. doi:
10.1016/j.jchromb.2011.03.050
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Masui. The Japanese journal of anesthesiology.
2011 Jun; 60(6):703-5. doi:
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British journal of anaesthesia.
2011 May; 106(5):665-74. doi:
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Journal of anaesthesiology, clinical pharmacology.
2011 Apr; 27(2):211-4. doi:
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Korean journal of anesthesiology.
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. [PMID: 22347654] - Alex Zwiers, Michiel van den Heuvel, Jean Smeets, Samantha Rutherford. Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach.
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Critical care research and practice.
2011; 2011(?):361737. doi:
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Masui. The Japanese journal of anesthesiology.
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British journal of anaesthesia.
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Masui. The Japanese journal of anesthesiology.
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Korean journal of anesthesiology.
2010 Feb; 58(2):136-41. doi:
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Masui. The Japanese journal of anesthesiology.
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Korean journal of anesthesiology.
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Indian journal of anaesthesia.
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Indian journal of anaesthesia.
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Revista espanola de anestesiologia y reanimacion.
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Saudi journal of anaesthesia.
2009 Jul; 3(2):83-6. doi:
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British journal of anaesthesia.
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Masui. The Japanese journal of anesthesiology.
2009 Jun; 58(6):762-4. doi:
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- Sampa Dutta Gupta, Soumendu Pal, Anupam Goswami, Sandip Bhadra, Sripurna Mandal, Chandashi Naskar, Sudakshina Mukherjee, Debasish Boral. A Comparative Study to Determine the Effect of Intravenous Magnesium on Postoperative Bleeding after on Pump CABG in Patients Receiving Pre-Operative Aspirin.
Indian journal of anaesthesia.
2009 Apr; 53(2):197-203. doi:
NULL
. [PMID: 20640123] - Sukran Geze, Ali Abbas Yilmaz, Filiz Tuzuner. The effect of scalp block and local infiltration on the haemodynamic and stress response to skull-pin placement for craniotomy.
European journal of anaesthesiology.
2009 Apr; 26(4):298-303. doi:
10.1097/eja.0b013e32831aedb2
. [PMID: 19262392] - Hans D de Boer. Neuromuscular transmission: new concepts and agents.
Journal of critical care.
2009 Mar; 24(1):36-42. doi:
10.1016/j.jcrc.2008.08.004
. [PMID: 19272537] - Jin Won Huh, Hoon Jung, Hye Sook Choi, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh. Efficacy of positive end-expiratory pressure titration after the alveolar recruitment manoeuvre in patients with acute respiratory distress syndrome.
Critical care (London, England).
2009; 13(1):R22. doi:
10.1186/cc7725
. [PMID: 19239703] - Bart A Ploeger, Jean Smeets, Ashley Strougo, Henk-Jan Drenth, Ge Ruigt, Natalie Houwing, Meindert Danhof. Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscular blockade by sugammadex.
Anesthesiology.
2009 Jan; 110(1):95-105. doi:
10.1097/aln.0b013e318190bc32
. [PMID: 19104176] - Man Liu, James P Dilger. Site selectivity of competitive antagonists for the mouse adult muscle nicotinic acetylcholine receptor.
Molecular pharmacology.
2009 Jan; 75(1):166-73. doi:
10.1124/mol.108.051060
. [PMID: 18842832] - Younsuk Lee, Sangseok Lee, Junyong In, Seung-Hyun Chung, Jun Heum Yon. Prediction of plasma hemoglobin concentration by near-infrared spectroscopy.
Journal of Korean medical science.
2008 Aug; 23(4):674-7. doi:
10.3346/jkms.2008.23.4.674
. [PMID: 18756056] - Yuko Sakata, Hiroki Wada, Takashi Oshima, Yoshihiko Aramaki, Yoshinori Kikuta, Yasuji Iwasaki. [Anesthetic management of a patient with transfusion-related acute lung injury (TRALI)].
Masui. The Japanese journal of anesthesiology.
2008 Aug; 57(8):1017-20. doi:
NULL
. [PMID: 18710014] - Shawn P Vorce, Craig T Mallak, Aaron Jacobs. Quantitative analysis of the aminosteroidal non-depolarizing neuromuscular blocking agent vecuronium by LC-ESI-MS: A Postmortem Investigation.
Journal of analytical toxicology.
2008 Jul; 32(6):422-7. doi:
10.1093/jat/32.6.422
. [PMID: 18652748] - Ju Mizuno, Kazumichi Yonenaga, Yoshikazu Mimura, Hideko Arita, Kazuo Hanaoka. [Hyperthermia and metabolic acidosis during subtotal thyroidectomy for a patient with Basedow's disease].
Masui. The Japanese journal of anesthesiology.
2008 Jul; 57(7):897-900. doi:
. [PMID: 18649649]
- Yuhong Li, Shengmei Zhu, Meijuan Yan. Combined general/epidural anesthesia (ropivacaine 0.375\%) versus general anesthesia for upper abdominal surgery.
Anesthesia and analgesia.
2008 May; 106(5):1562-5, table of contents. doi:
10.1213/ane.0b013e31816d1976
. [PMID: 18420877] - G Cammu, P J De Kam, I Demeyer, M Decoopman, P A M Peeters, J M W Smeets, L Foubert. Safety and tolerability of single intravenous doses of sugammadex administered simultaneously with rocuronium or vecuronium in healthy volunteers.
British journal of anaesthesia.
2008 Mar; 100(3):373-9. doi:
10.1093/bja/aem402
. [PMID: 18238834] - C Kaymak, B Karahalil, N N Ozcan, D Oztuna. Association between GSTP1 gene polymorphism and serum alpha-GST concentrations undergoing sevoflurane anaesthesia.
European journal of anaesthesiology.
2008 Mar; 25(3):193-9. doi:
10.1017/s0265021507002724
. [PMID: 17892615] - J López-Herce, M J Santiago, C Sánchez, S Mencía, A Carrillo, D Vigil. Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutrition.
European journal of clinical nutrition.
2008 Mar; 62(3):395-400. doi:
10.1038/sj.ejcn.1602710
. [PMID: 17327861] - Yi-Hong Ding, Chen-Yi Gu. [Effect of acupuncture--general anesthesia on hemodynamics in perioperative period of patients undergoing cholecystectomy].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2008 Mar; 28(3):206-8. doi:
"
. [PMID: 18476416] - Taketo Nakamura, Yutaka Oda, Mitsuji Matsushita, Takashi Mori, Kazutoshi Ikeshita, Akira Asada. [Anesthetic management for thymectomy in a patient with stiff-person syndrome].
Masui. The Japanese journal of anesthesiology.
2007 Oct; 56(10):1200-2. doi:
NULL
. [PMID: 17966628] - Avishai Ziser. Was it a true emergency?.
Anesthesia and analgesia.
2007 Sep; 105(3):876-7; author reply 878. doi:
10.1213/01.ane.0000268704.80213.fe
. [PMID: 17717254] - Philip M Jones, Timothy P Turkstra. Urgent usage of sugammadex to treat residual neuromuscular blockade in the PACU.
Anesthesia and analgesia.
2007 Sep; 105(3):877; author reply 878. doi:
10.1213/01.ane.0000268705.04400.10
. [PMID: 17717257] - David Wax. Where's the Fire?.
Anesthesia and analgesia.
2007 Sep; 105(3):877-8; author reply 878. doi:
10.1213/01.ane.0000268706.67403.61
. [PMID: 17717256] - Shinichiro Kira, Naozumi Takeshima, Junji Takatani, Akira Hasegawa, Hiroshi Miyakawa, Takayuki Noguchi. [Resistance to vecuronium bromide induced muscle relaxation in a patient with chronic renal failure and secondary hyperparathyroidism].
Masui. The Japanese journal of anesthesiology.
2007 Sep; 56(9):1091-3. doi:
NULL
. [PMID: 17877055] - Edwin J Rosman. Pseudo-emergent use of an investigational drug.
Anesthesia and analgesia.
2007 Sep; 105(3):876; author reply 876, 878. doi:
10.1213/01.ane.0000268702.75645.c0
. [PMID: 17717255] - Xin-Hua Yao, Pu Zhou, Zhen-Ke Xiao, Bao Wang, Chen-Yan Chen, Zhao-Hui Qing, Ji-Yun Liu. [Comparison of target controlled propofol infusion and sevoflurane inhalational anesthesia in laparoscopic cholecystectomy].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University.
2007 Aug; 27(8):1280-1, 1284. doi:
"
. [PMID: 17715049] - Rie Mieda, Chizu Aso, Koichi Nishikawa, Shigeru Saito, Fumio Goto. [Transient hyperglycemia following intra-peritoneal irrigation with 5\% glucose in a patient with pseudomyxoma peritonei].
Masui. The Japanese journal of anesthesiology.
2007 Aug; 56(8):959-61. doi:
NULL
. [PMID: 17715692] - Tomoko Morota, Katsuya Endo, Setsuo Furuta, Shinju Obara, Hiroshi Ohmuzo, Toshikazu Kaneko, Toshiyasu Onuma, Kazuhiro Watanabe. [Case of malignant hyperthermia in which treatment was carried out smoothly].
Masui. The Japanese journal of anesthesiology.
2007 Jul; 56(7):826-30. doi:
NULL
. [PMID: 17633846] - Tae-Soo Hahm, Jeong-Jin Lee, Mi-Kyung Yang, Jie-Ae Kim. Risk factors for an intraoperative arrhythmia during esophagectomy.
Yonsei medical journal.
2007 Jun; 48(3):474-9. doi:
10.3349/ymj.2007.48.3.474
. [PMID: 17594156] - Shoko Murakami, Tadanobu Yasuda, Tetsuya Kushikata, Hiroshi Hashimoto, Kazuyoshi Hirota. [Case of hemoglobinuria following glycerin enema].
Masui. The Japanese journal of anesthesiology.
2007 Jun; 56(6):689-91. doi:
. [PMID: 17571610]
- M Kanbak, A H Karagoz, N Erdem, B Oc, F Saricaoglu, N Ertas, A Berkkan, O Abbasoglu, U Aypar. Renal safety and extrahepatic defluorination of sevoflurane in hepatic transplantations.
Transplantation proceedings.
2007 Jun; 39(5):1544-8. doi:
10.1016/j.transproceed.2007.01.081
. [PMID: 17580185] - Tatsuya Ichinohe, Yuzuru Kaneko. Nitrous oxide does not aggravate postoperative emesis after orthognathic surgery in female and nonsmoking patients.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
2007 May; 65(5):936-9. doi:
10.1016/j.joms.2006.06.283
. [PMID: 17448844] - Mohamed Naguib. Sugammadex: another milestone in clinical neuromuscular pharmacology.
Anesthesia and analgesia.
2007 Mar; 104(3):575-81. doi:
10.1213/01.ane.0000244594.63318.fc
. [PMID: 17312211] - Jaishri Bogra, R Gangoo, V C Pandey, Pratima Srivastava. Effect on free radical generation with different anaesthesia.
Journal of the Indian Medical Association.
2007 Mar; 105(3):128-9, 132. doi:
. [PMID: 17824463]
- Pelin Cizmeci, Zerrin Ozkose. Magnesium sulphate as an adjuvant to total intravenous anesthesia in septorhinoplasty: a randomized controlled study.
Aesthetic plastic surgery.
2007 Mar; 31(2):167-73. doi:
10.1007/s00266-006-0194-5
. [PMID: 17437152] - Hao-Bo Yang, Qu-Lian Guo. [Effects of BIS and AEPindex monitoring on the depth of anesthesia in in intravenous-inhalational anesthesia anesthesia].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.
2007 Feb; 32(1):127-31. doi:
NULL
. [PMID: 17344602]