Hymecromone (BioDeep_00000398406)

Main id: BioDeep_00000000248

Secondary id: BioDeep_00000400189, BioDeep_00000860368

natural product PANOMIX_OTCML-2023


代谢物信息卡片


7-HYDROXY-4-METHYLCOUMARIN

化学式: C10H8O3 (176.0473418)
中文名称: 4-甲基伞形酮, 4-甲基伞形酮
谱图信息: 最多检出来源 Viridiplantae(plant) 1.59%

分子结构信息

SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)O
InChI: InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3

描述信息

CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3335; ORIGINAL_PRECURSOR_SCAN_NO 3333
A - Alimentary tract and metabolism > A05 - Bile and liver therapy > A05A - Bile therapy
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
C78272 - Agent Affecting Nervous System > C29698 - Antispasmodic Agent
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3322; ORIGINAL_PRECURSOR_SCAN_NO 3320
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3312; ORIGINAL_PRECURSOR_SCAN_NO 3309
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3317; ORIGINAL_PRECURSOR_SCAN_NO 3316
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3331; ORIGINAL_PRECURSOR_SCAN_NO 3329
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3329; ORIGINAL_PRECURSOR_SCAN_NO 3326
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7326; ORIGINAL_PRECURSOR_SCAN_NO 7323
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7324; ORIGINAL_PRECURSOR_SCAN_NO 7320
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7332; ORIGINAL_PRECURSOR_SCAN_NO 7328
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7358; ORIGINAL_PRECURSOR_SCAN_NO 7356
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7358; ORIGINAL_PRECURSOR_SCAN_NO 7355
CONFIDENCE standard compound; INTERNAL_ID 967; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7342; ORIGINAL_PRECURSOR_SCAN_NO 7340
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3396; ORIGINAL_PRECURSOR_SCAN_NO 3391
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3389; ORIGINAL_PRECURSOR_SCAN_NO 3387
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3360; ORIGINAL_PRECURSOR_SCAN_NO 3358
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3383; ORIGINAL_PRECURSOR_SCAN_NO 3380
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3365; ORIGINAL_PRECURSOR_SCAN_NO 3363
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3363; ORIGINAL_PRECURSOR_SCAN_NO 3361
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7291; ORIGINAL_PRECURSOR_SCAN_NO 7286
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7335; ORIGINAL_PRECURSOR_SCAN_NO 7331
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7307; ORIGINAL_PRECURSOR_SCAN_NO 7303
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7337; ORIGINAL_PRECURSOR_SCAN_NO 7335
CONFIDENCE standard compound; INTERNAL_ID 207; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7336; ORIGINAL_PRECURSOR_SCAN_NO 7332
CONFIDENCE standard compound; INTERNAL_ID 4193
4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.
4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.

同义名列表

4 个代谢物同义名

4-Methylumbelliferone; Hymecromone; 7-HYDROXY-4-METHYLCOUMARIN; 4-MU



数据库引用编号

66 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Noreen Halimani, Mikhail Nesterchuk, Alexandra A Tsitrina, Marat Sabirov, Irina N Andreichenko, Nataliya O Dashenkova, Elizaveta Petrova, Alexey M Kulikov, Timofei S Zatsepin, Roman A Romanov, Arsen S Mikaelyan, Yuri V Kotelevtsev. Knockdown of Hyaluronan synthase 2 suppresses liver fibrosis in mice via induction of transcriptomic changes similar to 4MU treatment. Scientific reports. 2024 02; 14(1):2797. doi: 10.1038/s41598-024-53089-x. [PMID: 38307876]
  • Alexandra A Tsitrina, Noreen Halimani, Irina N Andreichenko, Marat Sabirov, Mikhail Nesterchuk, Nataliya O Dashenkova, Roman Romanov, Elena V Bulgakova, Arsen Mikaelyan, Yuri Kotelevtsev. 4-Methylumbelliferone Targets Revealed by Public Data Analysis and Liver Transcriptome Sequencing. International journal of molecular sciences. 2023 Jan; 24(3):. doi: 10.3390/ijms24032129. [PMID: 36768453]
  • Joelle I Rosser, Nadine Nagy, Riya Goel, Gernot Kaber, Sally Demirdjian, Jamie Saxena, Jennifer B Bollyky, Adam R Frymoyer, Ana E Pacheco-Navarro, Elizabeth B Burgener, Jayakumar Rajadas, Zhe Wang, Olga Arbach, Colleen E Dunn, Anissa Kalinowski, Carlos E Milla, Paul L Bollyky. Oral hymecromone decreases hyaluronan in human study participants. The Journal of clinical investigation. 2022 05; 132(9):. doi: 10.1172/jci157983. [PMID: 35499083]
  • Shuai Yang, Yun Ling, Fang Zhao, Wei Li, Zhigang Song, Lu Wang, Qiuting Li, Mengxing Liu, Ying Tong, Lu Chen, Daoping Ru, Tongsheng Zhang, Kaicheng Zhou, Baolong Zhang, Peng Xu, Zhicong Yang, Wenxuan Li, Yuanlin Song, Jianqing Xu, Tongyu Zhu, Fei Shan, Wenqiang Yu, Hongzhou Lu. Hymecromone: a clinical prescription hyaluronan inhibitor for efficiently blocking COVID-19 progression. Signal transduction and targeted therapy. 2022 03; 7(1):91. doi: 10.1038/s41392-022-00952-w. [PMID: 35304437]
  • Rachel E Carlisle, Zahraa Mohammed-Ali, Chao Lu, Tamana Yousof, Victor Tat, Samera Nademi, Melissa E MacDonald, Richard C Austin, Jeffrey G Dickhout. TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease. Cell death & disease. 2021 10; 12(10):921. doi: 10.1038/s41419-021-04197-3. [PMID: 34625532]
  • Jing Chen, Jialin Meng, Chen Jin, Fan Mo, Yang Ding, Xiaomei Gao, Li Zhang, Meng Zhang, Chaozhao Liang. 4-Methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy for chronic prostatitis. The Prostate. 2021 10; 81(14):1078-1090. doi: 10.1002/pros.24205. [PMID: 34320251]
  • Alexandra A Tsitrina, Igor V Krasylov, Dmitry I Maltsev, Irina N Andreichenko, Viktoria S Moskvina, Dmitry N Ivankov, Elena V Bulgakova, Mikhail Nesterchuk, Vera Shashkovskaya, Nataliya O Dashenkova, Vladimir P Khilya, Arsen Mikaelyan, Yuri Kotelevtsev. Inhibition of hyaluronan secretion by novel coumarin compounds and chitin synthesis inhibitors. Glycobiology. 2021 09; 31(8):959-974. doi: 10.1093/glycob/cwab038. [PMID: 33978736]
  • Yoon Mee Yang, Zhijun Wang, Michitaka Matsuda, Ekihiro Seki. Inhibition of hyaluronan synthesis by 4-methylumbelliferone ameliorates non-alcoholic steatohepatitis in choline-deficient L-amino acid-defined diet-induced murine model. Archives of pharmacal research. 2021 Feb; 44(2):230-240. doi: 10.1007/s12272-021-01309-7. [PMID: 33486695]
  • Yanshan Zhong, Xiaodan Lu, Zhiwei Deng, Ziqing Lu, Minghui Fu. A 1232 bp upstream sequence of glutamine synthetase 1b from Eichhornia crassipes is a root-preferential promoter sequence. BMC plant biology. 2021 Jan; 21(1):66. doi: 10.1186/s12870-021-02832-x. [PMID: 33514320]
  • Yang-Liu Xia, Jing-Jing Wang, Shi-Yang Li, Yong Liu, Frank J Gonzalez, Ping Wang, Guang-Bo Ge. Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment. Bioorganic & medicinal chemistry. 2021 01; 29(?):115851. doi: 10.1016/j.bmc.2020.115851. [PMID: 33218896]
  • Pramod C Nair, Nuy Chau, Ross A McKinnon, John O Miners. Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity. Molecular pharmacology. 2020 12; 98(6):710-718. doi: 10.1124/molpharm.120.000104. [PMID: 33008919]
  • Yixuan Li, Weihua Zhang, Tingting Yin, Ce Wang, Feige Wang, Jing Sun, Lina Liu, Qinghuai Zhang, Chunze Zhang. Inhibition of UDP-glucuronosyltransferases by different furoquinoline alkaloids. Xenobiotica; the fate of foreign compounds in biological systems. 2020 Oct; 50(10):1170-1179. doi: 10.1080/00498254.2020.1760400. [PMID: 32367776]
  • Thea B Strøm, Terje Vinje, Katrine Bjune, Luís T da Costa, Jon K Laerdahl, Trond P Leren. Lysosomal acid lipase does not have a propeptide and should not be considered being a proprotein. Proteins. 2020 03; 88(3):440-448. doi: 10.1002/prot.25821. [PMID: 31587363]
  • Yi Cao, Laia Herrero-Nogareda, Nina Cedergreen. A comparative study of acetylcholinesterase and general-esterase activity assays using different substrates, in vitro and in vivo exposures and model organisms. Ecotoxicology and environmental safety. 2020 Feb; 189(?):109954. doi: 10.1016/j.ecoenv.2019.109954. [PMID: 31759743]
  • Irina N Andreichenko, Alexandra A Tsitrina, Alexander V Fokin, Adelya I Gabdulkhakova, Dmitry I Maltsev, Grigorii S Perelman, Elena V Bulgakova, Alexey M Kulikov, Arsen S Mikaelyan, Yuri V Kotelevtsev. 4-methylumbelliferone Prevents Liver Fibrosis by Affecting Hyaluronan Deposition, FSTL1 Expression and Cell Localization. International journal of molecular sciences. 2019 Dec; 20(24):. doi: 10.3390/ijms20246301. [PMID: 31847129]
  • Jennifer L McKimm-Breschkin, Susan Barrett, Charley McKenzie-Kludas, Julie McAuley, Victor A Streltsov, Stephen G Withers. Passaging of an influenza A(H1N1)pdm09 virus in a difluoro sialic acid inhibitor selects for a novel, but unfit I106M neuraminidase mutant. Antiviral research. 2019 09; 169(?):104542. doi: 10.1016/j.antiviral.2019.104542. [PMID: 31233807]
  • Yoon Mee Yang, Mazen Noureddin, Cheng Liu, Koichiro Ohashi, So Yeon Kim, Divya Ramnath, Elizabeth E Powell, Matthew J Sweet, Yoon Seok Roh, I-Fang Hsin, Nan Deng, Zhenqiu Liu, Jiurong Liang, Edward Mena, Daniel Shouhed, Robert F Schwabe, Dianhua Jiang, Shelly C Lu, Paul W Noble, Ekihiro Seki. Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Science translational medicine. 2019 06; 11(496):. doi: 10.1126/scitranslmed.aat9284. [PMID: 31189722]
  • Nadine Nagy, Irina Gurevich, Hedwich F Kuipers, Shannon M Ruppert, Payton L Marshall, Bryan J Xie, Wenchao Sun, Andrey V Malkovskiy, Jayakumar Rajadas, Maria Grandoch, Jens W Fischer, Adam R Frymoyer, Gernot Kaber, Paul L Bollyky. 4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition. The Journal of biological chemistry. 2019 05; 294(19):7864-7877. doi: 10.1074/jbc.ra118.006166. [PMID: 30914479]
  • Abel Suarez-Fueyo, Maria G Tsokos, Seung-Ki Kwok, Kayaho Maeda, Eri Katsuyama, Peter H Lapchak, George C Tsokos. Hyaluronic Acid Synthesis Contributes to Tissue Damage in Systemic Lupus Erythematosus. Frontiers in immunology. 2019; 10(?):2172. doi: 10.3389/fimmu.2019.02172. [PMID: 31572382]
  • Dan-Dan Tian, Joshua J Kellogg, Neşe Okut, Nicholas H Oberlies, Nadja B Cech, Danny D Shen, Jeannine S McCune, Mary F Paine. Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation. Drug metabolism and disposition: the biological fate of chemicals. 2018 05; 46(5):552-560. doi: 10.1124/dmd.117.079491. [PMID: 29467215]
  • Xia Lv, Jian-Bin Zhang, Xin-Xin Wang, Wen-Zhong Hu, Yu-Sheng Shi, Shu-Wen Liu, Da-Cheng Hao, Wei-Dong Zhang, Guang-Bo Ge, Jie Hou, Ling Yang. Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases. Chemico-biological interactions. 2018 Mar; 284(?):48-55. doi: 10.1016/j.cbi.2018.02.009. [PMID: 29470958]
  • Sara Stridh, Fredrik Palm, Tomoko Takahashi, Mayumi Ikegami-Kawai, Malou Friederich-Persson, Peter Hansell. Hyaluronan Production by Renomedullary Interstitial Cells: Influence of Endothelin, Angiotensin II and Vasopressin. International journal of molecular sciences. 2017 Dec; 18(12):. doi: 10.3390/ijms18122701. [PMID: 29236055]
  • Y-H Gong, G-M Ai, M Li, X-Y Shi, Q-Y Diao, X-W Gao. Functional characterization of carboxylesterase gene mutations involved in Aphis gossypii resistance to organophosphate insecticides. Insect molecular biology. 2017 12; 26(6):702-714. doi: 10.1111/imb.12331. [PMID: 28799241]
  • Jeroen van Smeden, Irini M Dijkhoff, Richard W J Helder, Hanin Al-Khakany, Daphne E C Boer, Anne Schreuder, Wouter W Kallemeijn, Samira Absalah, Herman S Overkleeft, Johannes M F G Aerts, Joke A Bouwstra. In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling. Journal of lipid research. 2017 12; 58(12):2299-2309. doi: 10.1194/jlr.m079376. [PMID: 29025868]
  • Jin-Shuai Lan, Yue Ding, Yun Liu, Ping Kang, Jian-Wei Hou, Xin-Yu Zhang, Sai-Sai Xie, Tong Zhang. Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease. European journal of medicinal chemistry. 2017 Oct; 139(?):48-59. doi: 10.1016/j.ejmech.2017.07.055. [PMID: 28797883]
  • Claire Grignon, Antoine Dupuis, Marion Albouy-Llaty, Maxime Condylis, Laurence Barrier, Pascal Carato, Bertrand Brunet, Virginie Migeot, Nicolas Venisse. Validation of a probe for assessing deconjugation of glucuronide and sulfate phase II metabolites assayed through LC-MS/MS in biological matrices. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Sep; 1061-1062(?):72-78. doi: 10.1016/j.jchromb.2017.07.013. [PMID: 28710970]
  • Guang Xian Pang, Chao Niu, Nuramina Mamat, Haji Akber Aisa. Synthesis and in vitro biological evaluation of novel coumarin derivatives containing isoxazole moieties on melanin synthesis in B16 cells and inhibition on bacteria. Bioorganic & medicinal chemistry letters. 2017 06; 27(12):2674-2677. doi: 10.1016/j.bmcl.2017.04.039. [PMID: 28476568]
  • Xin Liu, Yun-Feng Cao, Pei-Pei Dong, Liang-Liang Zhu, Zhenying Zhao, Xue Wu, Zhi-Wei Fu, Chun-Ting Huang, Zhong-Ze Fang, Hong-Zhi Sun. The inhibition of UDP-glucuronosyltransferases (UGTs) by vitamin A. Xenobiotica; the fate of foreign compounds in biological systems. 2017 May; 47(5):376-381. doi: 10.1080/00498254.2016.1198841. [PMID: 27359323]
  • H F Kuipers, N Nagy, S M Ruppert, V G Sunkari, P L Marshall, J A Gebe, H D Ishak, S G Keswani, J Bollyky, A R Frymoyer, T N Wight, L Steinman, P L Bollyky. The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice. Clinical and experimental immunology. 2016 09; 185(3):372-81. doi: 10.1111/cei.12815. [PMID: 27218304]
  • Si Liu, Anna Kulinich, Zhi P Cai, Hong Y Ma, Ya M Du, Yong M Lv, Li Liu, Josef Voglmeir. The fucosidase-pool of Emticicia oligotrophica: Biochemical characterization and transfucosylation potential. Glycobiology. 2016 08; 26(8):871-879. doi: 10.1093/glycob/cww030. [PMID: 26941394]
  • . Pancreatic lipase and α-amylase inhibitory activities of plants used in Traditional Chinese Medicine (TCM). Die Pharmazie. 2016 Jul; 71(7):420-424. doi: 10.1691/ph.2016.6569. [PMID: 29441920]
  • Xia Lv, Xin-Xin Wang, Jie Hou, Zhong-Ze Fang, Jing-Jing Wu, Yun-Feng Cao, Shu-Wen Liu, Guang-Bo Ge, Ling Yang. Comparison of the inhibitory effects of tolcapone and entacapone against human UDP-glucuronosyltransferases. Toxicology and applied pharmacology. 2016 06; 301(?):42-9. doi: 10.1016/j.taap.2016.04.009. [PMID: 27089846]
  • F Tang, Y Xiong, H Zhang, K Wu, Y Xiang, J-B Shao, H-W Ai, Y-P Xiang, X-L Zheng, J-R Lv, H Sun, L-S Bao, Z Zhang, H-B Hu, J-Y Zhang, L Chen, J Lu, W-Y Liu, H Mei, Y Ma, C-F Xu, A-Y Fang, M Gu, C-Y Xu, Y Chen, Z Chen, Z-Y Sun. Visual detection technique for efficient screening and isolation of Salmonella based on a novel enrichment assay using chromatography membrane. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2016 Mar; 35(3):353-61. doi: 10.1007/s10096-015-2543-2. [PMID: 26796551]
  • Mingjie Tang, Yanjie Guo, Youshui Gao, Chao Tang, Xiaoqian Dang, Zubin Zhou, Yuqiang Sun, Kunzheng Wang. Albumin's Influence on Carprofen Enantiomers-Hymecromone Interaction. Chirality. 2016 Mar; 28(3):226-9. doi: 10.1002/chir.22562. [PMID: 26708612]
  • Vivekanand Tiwari, Manish Kumar Patel, Amit Kumar Chaturvedi, Avinash Mishra, Bhavanath Jha. Functional Characterization of the Tau Class Glutathione-S-Transferases Gene (SbGSTU) Promoter of Salicornia brachiata under Salinity and Osmotic Stress. PloS one. 2016; 11(2):e0148494. doi: 10.1371/journal.pone.0148494. [PMID: 26885663]
  • N V Olkhovych. Chitotriosidase activity as additional biomarker in the diagnosis of lysosomal storage diseases. Ukrainian biochemical journal. 2016 Jan; 88(1):69-78. doi: 10.15407/ubj88.01.069. [PMID: 29227082]
  • Qian Zhang, Yun-Feng Cao, Rui-Xue Ran, Rong-Shan Li, Xue Wu, Pei-Pei Dong, Yan-Yan Zhang, Cui-Min Hu, Wei-Ming Wang. Strong Specific Inhibition of UDP-glucuronosyltransferase 2B7 by Atractylenolide I and III. Phytotherapy research : PTR. 2016 Jan; 30(1):25-30. doi: 10.1002/ptr.5496. [PMID: 26536846]
  • Dan Liu, Jie Wu, Hongbo Xie, Mingyi Liu, Isaiah Takau, Hong Zhang, Yuqing Xiong, Chunhua Xia. Inhibitory Effect of Hesperetin and Naringenin on Human UDP-Glucuronosyltransferase Enzymes: Implications for Herb-Drug Interactions. Biological & pharmaceutical bulletin. 2016; 39(12):2052-2059. doi: 10.1248/bpb.b16-00581. [PMID: 27904048]
  • Travis J Yates, Luis E Lopez, Soum D Lokeshwar, Nicolas Ortiz, Georgios Kallifatidis, Andre Jordan, Kelly Hoye, Norman Altman, Vinata B Lokeshwar. Dietary supplement 4-methylumbelliferone: an effective chemopreventive and therapeutic agent for prostate cancer. Journal of the National Cancer Institute. 2015 Jul; 107(7):. doi: 10.1093/jnci/djv085. [PMID: 25868577]
  • Akihiro Ogawa, Toshiya Kobayashi, Fumihiko Sakai, Yukio Kadooka, Yoshihiro Kawasaki. Lactobacillus gasseri SBT2055 suppresses fatty acid release through enlargement of fat emulsion size in vitro and promotes fecal fat excretion in healthy Japanese subjects. Lipids in health and disease. 2015 Mar; 14(?):20. doi: 10.1186/s12944-015-0019-0. [PMID: 25884980]
  • Jianbin Zhang, Yan Lv, Bing Wang, Shan Zhao, Mingqian Tan, Guojun Lv, Xiaojun Ma. Influence of microemulsion-mucin interaction on the fate of microemulsions diffusing through pig gastric mucin solutions. Molecular pharmaceutics. 2015 Mar; 12(3):695-705. doi: 10.1021/mp500475y. [PMID: 25608210]
  • Brandon T Gufford, Gang Chen, Philip Lazarus, Tyler N Graf, Nicholas H Oberlies, Mary F Paine. Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation. Drug metabolism and disposition: the biological fate of chemicals. 2014 Oct; 42(10):1675-83. doi: 10.1124/dmd.114.059451. [PMID: 25008344]
  • Mi-Ok Sim, Ju Ri Ham, Hae-In Lee, Kwon-Il Seo, Mi-Kyung Lee. Long-term supplementation of umbelliferone and 4-methylumbelliferone alleviates high-fat diet induced hypertriglyceridemia and hyperglycemia in mice. Chemico-biological interactions. 2014 Jun; 216(?):9-16. doi: 10.1016/j.cbi.2014.03.003. [PMID: 24661945]
  • Jianbin Zhang, Yan Lv, Shan Zhao, Bing Wang, Mingqian Tan, Hongguo Xie, Guojun Lv, Xiaojun Ma. Effect of lipolysis on drug release from self-microemulsifying drug delivery systems (SMEDDS) with different core/shell drug location. AAPS PharmSciTech. 2014 Jun; 15(3):731-40. doi: 10.1208/s12249-014-0096-9. [PMID: 24554238]
  • Aditya G Kohli, Heidi M Kieler-Ferguson, Darren Chan, Francis C Szoka. A robust and quantitative method for tracking liposome contents after intravenous administration. Journal of controlled release : official journal of the Controlled Release Society. 2014 Feb; 176(?):86-93. doi: 10.1016/j.jconrel.2013.12.014. [PMID: 24368300]
  • Yan Fang, Hua Wang, Wenjuan Zhu, Lu Wang, Hengjiang Liu, Yue He, Xu Xu, Weimin Yin, Yanghu Sima, Shiqing Xu. Antioxidative capacity in the fat body of Bombyx mori is increased following oral administration of 4-methylumbelliferone. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2014 Jan; 159(?):31-7. doi: 10.1016/j.cbpc.2013.09.003. [PMID: 24080584]
  • Zhong-Ze Fang, Rong-Rong He, Yun-Feng Cao, Naoki Tanaka, Changtao Jiang, Kristopher W Krausz, Yunpeng Qi, Pei-Pei Dong, Chun-Zhi Ai, Xiao-Yu Sun, Mo Hong, Guang-Bo Ge, Frank J Gonzalez, Xiao-Chi Ma, Hong-Zhi Sun. A model of in vitro UDP-glucuronosyltransferase inhibition by bile acids predicts possible metabolic disorders. Journal of lipid research. 2013 Dec; 54(12):3334-44. doi: 10.1194/jlr.m040519. [PMID: 24115227]
  • Sara Stridh, Fredrik Palm, Peter Hansell. Inhibition of hyaluronan synthesis in rats reduces renal ability to excrete fluid and electrolytes during acute hydration. Upsala journal of medical sciences. 2013 Nov; 118(4):217-21. doi: 10.3109/03009734.2013.834013. [PMID: 24102146]
  • Vanessa Colombaro, Anne-Emilie Declèves, Inès Jadot, Virginie Voisin, Laetitia Giordano, Isabelle Habsch, Denis Nonclercq, Bruno Flamion, Nathalie Caron. Inhibition of hyaluronan is protective against renal ischaemia-reperfusion injury. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2013 Oct; 28(10):2484-93. doi: 10.1093/ndt/gft314. [PMID: 24078641]
  • Z Shu-Yao, J Hong, L Chao-Xian, Z Zhi-Wei, Xin Dai-Shan, C Lei. In vitro evidence of possible influence of scutellarein towards bile acids' metabolism. African health sciences. 2013 Sep; 13(3):556-9. doi: 10.4314/ahs.v13i3.4. [PMID: 24250288]
  • Cécile Ouairy, Thierry Cresteil, Bernard Delpech, David Crich. Synthesis and evaluation of 3-deoxy and 3-deoxy-3-fluoro derivatives of gluco- and manno-configured tetrahydropyridoimidazole glycosidase inhibitors. Carbohydrate research. 2013 Aug; 377(?):35-43. doi: 10.1016/j.carres.2013.05.011. [PMID: 23792222]
  • Amira Mira, Akinobu Tanaka, Yumie Tateyama, Ryuichiro Kondo, Kuniyoshi Shimizu. Comparative biological study of roots, stems, leaves, and seeds of Angelica shikokiana Makino. Journal of ethnopharmacology. 2013 Jul; 148(3):980-7. doi: 10.1016/j.jep.2013.06.008. [PMID: 23769982]
  • Anaid Benitez, Travis J Yates, N Shamaldevi, Tim Bowen, Vinata B Lokeshwar. Dietary supplement hymecromone and sorafenib: a novel combination for the control of renal cell carcinoma. The Journal of urology. 2013 Jul; 190(1):285-90. doi: 10.1016/j.juro.2012.12.011. [PMID: 23228386]
  • Ming-Lian Yu, Yue Yang, Cong-Min Wang, Meng-Meng Zhang, Miao-Chun Bai, Yue-Ling Guo. Acitretin exhibits inhibitory effects towards UDP-glucuronosyltransferase (UGT)1A9-mediated 4-methylumbelliferone (4-MU) and propofol glucuronidation reaction. Die Pharmazie. 2013 Jun; 68(6):449-52. doi: . [PMID: 23875253]
  • Yutaka Yoshioka, Eiji Kozawa, Hiroshi Urakawa, Eisuke Arai, Naohisa Futamura, Lisheng Zhuo, Koji Kimata, Naoki Ishiguro, Yoshihiro Nishida. Suppression of hyaluronan synthesis alleviates inflammatory responses in murine arthritis and in human rheumatoid synovial fibroblasts. Arthritis and rheumatism. 2013 May; 65(5):1160-70. doi: 10.1002/art.37861. [PMID: 23335273]
  • Zhuo Luan, Linjing Li, Katsumi Higaki, Eiji Nanba, Yoshiyuki Suzuki, Kousaku Ohno. The chaperone activity and toxicity of ambroxol on Gaucher cells and normal mice. Brain & development. 2013 Apr; 35(4):317-22. doi: 10.1016/j.braindev.2012.05.008. [PMID: 22682976]
  • Zhong-Ze Fang, Yun-Feng Cao, Cui-Min Hu, Mo Hong, Xiao-Yu Sun, Guang-Bo Ge, Yong Liu, Yan-Yan Zhang, Ling Yang, Hong-Zhi Sun. Structure-inhibition relationship of ginsenosides towards UDP-glucuronosyltransferases (UGTs). Toxicology and applied pharmacology. 2013 Mar; 267(2):149-54. doi: 10.1016/j.taap.2012.12.019. [PMID: 23306165]
  • Rui-Hua Dong, Zhong-Ze Fang, Liang-Liang Zhu, Guang-Bo Ge, Xiao-Bao Li, Cui-Min Hu, Yun-Feng Cao, Yang-Liu Xia, Ling Yang, Ze-Yuan Liu. Deep understanding of the interaction between thienorphine and UDP-glucuronosyltransferase (UGT) isoforms. Xenobiotica; the fate of foreign compounds in biological systems. 2013 Feb; 43(2):133-9. doi: 10.3109/00498254.2012.706723. [PMID: 22813462]
  • Bindumadhav M Marathe, Vincent Lévêque, Klaus Klumpp, Robert G Webster, Elena A Govorkova. Determination of neuraminidase kinetic constants using whole influenza virus preparations and correction for spectroscopic interference by a fluorogenic substrate. PloS one. 2013; 8(8):e71401. doi: 10.1371/journal.pone.0071401. [PMID: 23977037]
  • Archit Garg, Darla Mark Manidhar, Mahesh Gokara, Chandramouli Malleda, Cirandur Suresh Reddy, Rajagopal Subramanyam. Elucidation of the binding mechanism of coumarin derivatives with human serum albumin. PloS one. 2013; 8(5):e63805. doi: 10.1371/journal.pone.0063805. [PMID: 23724004]
  • Nenad Manevski, Jari Yli-Kauhaluoma, Moshe Finel. UDP-glucuronic acid binds first and the aglycone substrate binds second to form a ternary complex in UGT1A9-catalyzed reactions, in both the presence and absence of bovine serum albumin. Drug metabolism and disposition: the biological fate of chemicals. 2012 Nov; 40(11):2192-203. doi: 10.1124/dmd.112.047746. [PMID: 22912433]
  • Mariana Silvia Cretoiu, Anna Maria Kielak, Waleed Abu Al-Soud, Søren J Sørensen, Jan Dirk van Elsas. Mining of unexplored habitats for novel chitinases--chiA as a helper gene proxy in metagenomics. Applied microbiology and biotechnology. 2012 Jun; 94(5):1347-58. doi: 10.1007/s00253-012-4057-5. [PMID: 22526805]
  • Alan S Cross, Sang Won Hyun, Alba Miranda-Ribera, Chiguang Feng, Anguo Liu, Chinh Nguyen, Lei Zhang, Irina G Luzina, Sergei P Atamas, William S Twaddell, Wei Guang, Erik P Lillehoj, Adam C Puché, Wei Huang, Lai-Xi Wang, Antonino Passaniti, Simeon E Goldblum. NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not. The Journal of biological chemistry. 2012 May; 287(19):15966-80. doi: 10.1074/jbc.m112.346817. [PMID: 22403397]
  • Gulhan Cakır, Seyfettin Gumus, Ergun Ucar, Hatice Kaya, Ergun Tozkoparan, Emin Ozgur Akgul, Bulent Karaman, Omer Deniz, Ismail Kurt, Metin Ozkan, Hayati Bilgic. Serum chitotriosidase activity in pulmonary tuberculosis: response to treatment and correlations with clinical parameters. Annals of laboratory medicine. 2012 May; 32(3):184-9. doi: 10.3343/alm.2012.32.3.184. [PMID: 22563552]
  • Shu-Xiao Zheng, Shi Xiao, Mee-Len Chye. The gene encoding Arabidopsis acyl-CoA-binding protein 3 is pathogen inducible and subject to circadian regulation. Journal of experimental botany. 2012 May; 63(8):2985-3000. doi: 10.1093/jxb/ers009. [PMID: 22345636]
  • Nam-Hee Kang, Won Kyung Lee, Bo-Rim Yi, Min-Ah Park, Hye-Rim Lee, Sang-Ki Park, Kyung-A Hwang, Hyoung Kook Park, Kyung-Chul Choi. Modulation of lipid metabolism by mixtures of protamine and chitooligosaccharide through pancreatic lipase inhibitory activity in a rat model. Laboratory animal research. 2012 Mar; 28(1):31-8. doi: 10.5625/lar.2012.28.1.31. [PMID: 22474472]
  • Ok Jeong Lee, Su-Jin Kim, Young Bae Sohn, Hyung-Doo Park, Soo-Youn Lee, Chi-Hwa Kim, Ah-Ra Ko, Yeon-Joo Yook, Su-Jin Lee, Sung Won Park, Se-Hwa Kim, Sung-Yoon Cho, Eun-Kyung Kwon, Sun Ju Han, Dong-Kyu Jin. A study of the relationship between clinical phenotypes and plasma iduronate-2-sulfatase enzyme activities in Hunter syndrome patients. Korean journal of pediatrics. 2012 Mar; 55(3):88-92. doi: 10.3345/kjp.2012.55.3.88. [PMID: 22474463]
  • Jaroslav Matoušek, Tomáš Kocábek, Josef Patzak, Zoltán Füssy, Jitka Procházková, Arne Heyerick. Combinatorial analysis of lupulin gland transcription factors from R2R3Myb, bHLH and WDR families indicates a complex regulation of chs_H1 genes essential for prenylflavonoid biosynthesis in hop (Humulus Lupulus L.). BMC plant biology. 2012 Feb; 12(?):27. doi: 10.1186/1471-2229-12-27. [PMID: 22340661]
  • Rui-Hua Dong, Zhong-Ze Fang, Liang-Liang Zhu, Si-Cheng Liang, Guang-Bo Ge, Ling Yang, Ze-Yuan Liu. Investigation of UDP-glucuronosyltransferases (UGTs) inhibitory properties of carvacrol. Phytotherapy research : PTR. 2012 Jan; 26(1):86-90. doi: 10.1002/ptr.3525. [PMID: 21544887]
  • M G L Basurto-Cadena, M Vázquez-Arista, J García-Jiménez, R Salcedo-Hernández, D K Bideshi, J E Barboza-Corona. Isolation of a new Mexican strain of Bacillus subtilis with antifungal and antibacterial activities. TheScientificWorldJournal. 2012; 2012(?):384978. doi: 10.1100/2012/384978. [PMID: 22593682]
  • Nicola Martinelli, Roberta Micaglio, Letizia Consoli, Patrizia Guarini, Elisa Grison, Francesca Pizzolo, Simonetta Friso, Elisabetta Trabetti, Pier Franco Pignatti, Roberto Corrocher, Oliviero Olivieri, Domenico Girelli. Low levels of serum paraoxonase activities are characteristic of metabolic syndrome and may influence the metabolic-syndrome-related risk of coronary artery disease. Experimental diabetes research. 2012; 2012(?):231502. doi: 10.1155/2012/231502. [PMID: 21960992]
  • Stephen J Genuis, Sanjay Beesoon, Detlef Birkholz, Rebecca A Lobo. Human excretion of bisphenol A: blood, urine, and sweat (BUS) study. Journal of environmental and public health. 2012; 2012(?):185731. doi: 10.1155/2012/185731. [PMID: 22253637]
  • Gabriella Cotugno, Patrizia Annunziata, Maria Vittoria Barone, Marianthi Karali, Sandro Banfi, Alberto Auricchio. Impact of age at administration, lysosomal storage, and transgene regulatory elements on AAV2/8-mediated rat liver transduction. PloS one. 2012; 7(3):e33286. doi: 10.1371/journal.pone.0033286. [PMID: 22428010]
  • Maria Vardakou, Frank Sainsbury, Neil Rigby, Francis Mulholland, George P Lomonossoff. Expression of active recombinant human gastric lipase in Nicotiana benthamiana using the CPMV-HT transient expression system. Protein expression and purification. 2012 Jan; 81(1):69-74. doi: 10.1016/j.pep.2011.09.005. [PMID: 21945702]
  • Dietmar Funck, Karen Clauß, Wolf B Frommer, Hanjo A Hellmann. The Arabidopsis CstF64-Like RSR1/ESP1 Protein Participates in Glucose Signaling and Flowering Time Control. Frontiers in plant science. 2012; 3(?):80. doi: 10.3389/fpls.2012.00080. [PMID: 22629280]
  • Paola C Zucchi, Michael Zick. Membrane fusion catalyzed by a Rab, SNAREs, and SNARE chaperones is accompanied by enhanced permeability to small molecules and by lysis. Molecular biology of the cell. 2011 Dec; 22(23):4635-46. doi: 10.1091/mbc.e11-08-0680. [PMID: 21976702]
  • Mukadder Atmaca, Hakkı Murat Bilgin, Basra Deniz Obay, Hüda Diken, Mustafa Kelle, Ebru Kale. The hepatoprotective effect of coumarin and coumarin derivates on carbon tetrachloride-induced hepatic injury by antioxidative activities in rats. Journal of physiology and biochemistry. 2011 Dec; 67(4):569-76. doi: 10.1007/s13105-011-0103-5. [PMID: 21656273]
  • Maria S Dwiyanti, Tetsuya Yamada, Masako Sato, Jun Abe, Keisuke Kitamura. Genetic variation of γ-tocopherol methyltransferase gene contributes to elevated α-tocopherol content in soybean seeds. BMC plant biology. 2011 Nov; 11(?):152. doi: 10.1186/1471-2229-11-152. [PMID: 22053941]
  • Xiang Li, Ming-Jun Gao. Modulation of root branching by a coumarin derivative. Plant signaling & behavior. 2011 Nov; 6(11):1654-5. doi: 10.4161/psb.6.11.17768. [PMID: 22057336]
  • Nenad Manevski, Paolo Svaluto Moreolo, Jari Yli-Kauhaluoma, Moshe Finel. Bovine serum albumin decreases Km values of human UDP-glucuronosyltransferases 1A9 and 2B7 and increases Vmax values of UGT1A9. Drug metabolism and disposition: the biological fate of chemicals. 2011 Nov; 39(11):2117-29. doi: 10.1124/dmd.111.041418. [PMID: 21856742]
  • Daisuke Tamaoki, Ichirou Karahara, Takumi Nishiuchi, Tatsuya Wakasugi, Kyoji Yamada, Seiichiro Kamisaka. Involvement of auxin dynamics in hypergravity-induced promotion of lignin-related gene expression in Arabidopsis inflorescence stems. Journal of experimental botany. 2011 Nov; 62(15):5463-9. doi: 10.1093/jxb/err224. [PMID: 21841171]
  • Paul J Orchard, Troy Lund, Wes Miller, Steven M Rothman, Gerald Raymond, David Nascene, Lisa Basso, James Cloyd, Jakub Tolar. Chitotriosidase as a biomarker of cerebral adrenoleukodystrophy. Journal of neuroinflammation. 2011 Oct; 8(?):144. doi: 10.1186/1742-2094-8-144. [PMID: 22014002]
  • Jerusa A Q A Faria, Pedro A B Reis, Marco T B Reis, Gustavo L Rosado, Guilherme L Pinheiro, Giselle C Mendes, Elizabeth P B Fontes. The NAC domain-containing protein, GmNAC6, is a downstream component of the ER stress- and osmotic stress-induced NRP-mediated cell-death signaling pathway. BMC plant biology. 2011 Sep; 11(?):129. doi: 10.1186/1471-2229-11-129. [PMID: 21943253]
  • Ayako Kato, Jun Ueyama, Fumie Abe, Kazuo Hotta, Ikuto Tsukiyama, Taeyuki Oshima, Fumio Kondo, Hiroko Saito, Takaaki Hasegawa. Panipenem does not alter the pharmacokinetics of the active metabolite of irinotecan SN-38 and inactive metabolite SN-38 glucuronide (SN-38G) in rats. Anticancer research. 2011 Sep; 31(9):2915-22. doi: . [PMID: 21868538]
  • Xiang Li, Margaret Y Gruber, Dwayne D Hegedus, Derek J Lydiate, Ming-Jun Gao. Effects of a coumarin derivative, 4-methylumbelliferone, on seed germination and seedling establishment in Arabidopsis. Journal of chemical ecology. 2011 Aug; 37(8):880-90. doi: 10.1007/s10886-011-9987-3. [PMID: 21713565]
  • Cristian Calderon, Elsa Abuin, Eduardo Lissi, Rodrigo Montecinos. Effect of human serum albumin on the kinetics of 4-methylumbelliferyl-β-D-N-N'-N″ Triacetylchitotrioside hydrolysis catalyzed by hen egg white lysozyme. The protein journal. 2011 Aug; 30(6):367-73. doi: 10.1007/s10930-011-9339-8. [PMID: 21748378]
  • David G J Mann, Zachary R King, Wusheng Liu, Blake L Joyce, Ryan J Percifield, Jennifer S Hawkins, Peter R LaFayette, Barbara J Artelt, Jason N Burris, Mitra Mazarei, Jeffrey L Bennetzen, Wayne A Parrott, Charles N Stewart. Switchgrass (Panicum virgatum L.) polyubiquitin gene (PvUbi1 and PvUbi2) promoters for use in plant transformation. BMC biotechnology. 2011 Jul; 11(?):74. doi: 10.1186/1472-6750-11-74. [PMID: 21745390]
  • Yan Liang, Wen-juan Deng, Liang-bin Zhou, Chun-yan Yan, Rong-min Yu. [Biotransformation of 4-methyl-7-allyloxy coumarin by transgenic hairy roots of Polygonum multiflorum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Jun; 34(6):901-4. doi: ". [PMID: 22017006]
  • Hakkı Murat Bilgin, Mukadder Atmaca, Basra Deniz Obay, Selver Ozekinci, Ezel Taşdemir, Aydın Ketani. Protective effects of coumarin and coumarin derivatives against carbon tetrachloride-induced acute hepatotoxicity in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 2011 May; 63(4):325-30. doi: 10.1016/j.etp.2010.02.006. [PMID: 20207117]
  • Liran I Shlush, Shalev Itzkovitz, Ariel Cohen, Aviad Rutenberg, Ron Berkovitz, Shiran Yehezkel, Hofit Shahar, Sara Selig, Karl Skorecki. Quantitative digital in situ senescence-associated β-galactosidase assay. BMC cell biology. 2011 Apr; 12(?):16. doi: 10.1186/1471-2121-12-16. [PMID: 21496240]
  • Jiping Wang, Allan M Evans, Kathleen M Knights, John O Miners. Differential disposition of intra-renal generated and preformed glucuronides: studies with 4-methylumbelliferone and 4-methylumbelliferyl glucuronide in the filtering and nonfiltering isolated perfused rat kidney. The Journal of pharmacy and pharmacology. 2011 Apr; 63(4):507-14. doi: 10.1111/j.2042-7158.2010.01244.x. [PMID: 21401602]
  • Heli Simojoki, Tiina Salomäki, Suvi Taponen, Antti Iivanainen, Satu Pyörälä. Innate immune response in experimentally induced bovine intramammary infection with Staphylococcus simulans and S. epidermidis. Veterinary research. 2011 Mar; 42(?):49. doi: 10.1186/1297-9716-42-49. [PMID: 21414189]
  • Nobuaki Ishihama, Reiko Yamada, Miki Yoshioka, Shinpei Katou, Hirofumi Yoshioka. Phosphorylation of the Nicotiana benthamiana WRKY8 transcription factor by MAPK functions in the defense response. The Plant cell. 2011 Mar; 23(3):1153-70. doi: 10.1105/tpc.110.081794. [PMID: 21386030]
  • Peter I MacKenzie, Anne Rogers, David J Elliot, Nuy Chau, Julie-Ann Hulin, John O Miners, Robyn Meech. The novel UDP glycosyltransferase 3A2: cloning, catalytic properties, and tissue distribution. Molecular pharmacology. 2011 Mar; 79(3):472-8. doi: 10.1124/mol.110.069336. [PMID: 21088224]
  • Ting Yuan, Xianghua Li, Jinghua Xiao, Shiping Wang. Characterization of Xanthomonas oryzae-responsive cis-acting element in the promoter of rice race-specific susceptibility gene Xa13. Molecular plant. 2011 Mar; 4(2):300-9. doi: 10.1093/mp/ssq076. [PMID: 21208999]
  • Jin Zhou, Timothy S Tracy, Rory P Remmel. Correlation between bilirubin glucuronidation and estradiol-3-gluronidation in the presence of model UDP-glucuronosyltransferase 1A1 substrates/inhibitors. Drug metabolism and disposition: the biological fate of chemicals. 2011 Feb; 39(2):322-9. doi: 10.1124/dmd.110.035030. [PMID: 21030469]
  • Ryan T Bushey, Gang Chen, Andrea S Blevins-Primeau, Jacek Krzeminski, Shantu Amin, Philip Lazarus. Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis. Pharmacogenetics and genomics. 2011 Feb; 21(2):55-65. doi: 10.1097/fpc.0b013e328341db05. [PMID: 21164388]
  • Hoang Trong Phan, Udo Conrad. Membrane-based inverse transition cycling: an improved means for purifying plant-derived recombinant protein-elastin-like polypeptide fusions. International journal of molecular sciences. 2011; 12(5):2808-21. doi: 10.3390/ijms12052808. [PMID: 21686152]
  • Mamiko Shimazaki, Keiko Fujita, Hironori Kobayashi, Shunji Suzuki. Pink-colored grape berry is the result of short insertion in intron of color regulatory gene. PloS one. 2011; 6(6):e21308. doi: 10.1371/journal.pone.0021308. [PMID: 21695059]