2-Methylanthraquinone (BioDeep_00000396352)

 

Secondary id: BioDeep_00000008074

PANOMIX_OTCML-2023 Volatile Flavor Compounds natural product


代谢物信息卡片


InChI=1/C15H10O2/c1-9-6-7-12-13(8-9)15(17)11-5-3-2-4-10(11)14(12)16/h2-8H,1H

化学式: C15H10O2 (222.06807600000002)
中文名称: 2-甲基蒽醌
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 1.41%

分子结构信息

SMILES: c1ccc2c(c1)C(=O)c1c(C2=O)ccc(c1)C
InChI: InChI=1S/C15H10O2/c1-9-6-7-12-13(8-9)15(17)11-5-3-2-4-10(11)14(12)16/h2-8H,1H3

描述信息

2-methylanthraquinone is an anthraquinone that is 9,10-anthraquinone in which the hydrogen at position 2 is substituted by a methyl group. It is functionally related to a 9,10-anthraquinone.
2-Methylanthraquinone is a natural product found in Clausena heptaphylla, Ophiorrhiza pumila, and other organisms with data available.
Tectoquinone (2-Methylanthraquinone) is a SARSCoV-2 main protease inhibitor against COVID-19. Tectoquinone exhibits strong mosquito larvicidal activity with the LC50 values of 3.3 and 5.4 μg/ml against A. aegypti and A. albopictus in 24 h, respectively[1][2].
Tectoquinone (2-Methylanthraquinone) is a SARSCoV-2 main protease inhibitor against COVID-19. Tectoquinone exhibits strong mosquito larvicidal activity with the LC50 values of 3.3 and 5.4 μg/ml against A. aegypti and A. albopictus in 24 h, respectively[1][2].

同义名列表

30 个代谢物同义名

InChI=1/C15H10O2/c1-9-6-7-12-13(8-9)15(17)11-5-3-2-4-10(11)14(12)16/h2-8H,1H; 2-Methylanthraquinone, technical, >=95\\% (HPLC); Ethyl 2-cyano-2-(4-fluoro-2-nitrophenyl)acetate; 2-methyl-9,10-dihydroanthracene-9,10-dione; 2-Methyl anthraquinone;Tectoquinone; 9,10-Anthracenedione, 2-methyl-; 2-methyl-anthracene-9,10-dione; 2-methyl-9,10-anthracenedione; 2-methylanthracene-9,10-dione; 2-Methyl-9,10-anthraquinone; 2-Methylanthra-9,10-quinone; 2-METHYLANTHRAQUINONE [MI]; .beta.-Methylanthraquinone; beta-Methylanthraquinone; Anthraquinone, 2-methyl-; METHYLANTHRAQUINONE, 2-; 2-Methyl anthraquinone; 2-Methyl-Anthraquinone; 2-Methylanthraquinone; UNII-Q9P233HWAJ; Techtoquinone; Tectoquinone; 9, 2-methyl-; Tox21_302044; CAS-84-54-8; Tectochinon; Q9P233HWAJ; AI3-15182; 2-MAQ; Tectoquinone



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

93 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Phoebe Sussana Primus, Carol Hsin-Yi Wu, Chai-Lin Kao, Yeun-Mun Choo. Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton. Natural product research. 2022 Nov; ?(?):1-8. doi: 10.1080/14786419.2022.2147932. [PMID: 36416441]
  • Yulia Anita, Syelvia Putri Utami, Hiroshi Ohi, Evelyn Evelyn, Akiko Nakagawa-Izumi. Mutagenicity of Tectona grandis Wood Extracts and Their Ability to Improve Carbohydrate Yield for Kraft Cooking Eucalyptus Wood. Molecules (Basel, Switzerland). 2021 Nov; 26(23):. doi: 10.3390/molecules26237171. [PMID: 34885752]
  • Phi-Hung Nguyen, Hong Seok Choi, Thi Kim Quy Ha, Ji Yeon Seo, Jun-Li Yang, Da-Woon Jung, Darren R Williams, Won-Keun Oh. Anthraquinones from Morinda longissima and their insulin mimetic activities via AMP-activated protein kinase (AMPK) activation. Bioorganic & medicinal chemistry letters. 2017 01; 27(1):40-44. doi: 10.1016/j.bmcl.2016.11.034. [PMID: 27887844]
  • Yun-Lan Li, Jiali Zhang, Dong Min, Zhou Hongyan, Niu Lin, Qing-Shan Li. Anticancer Effects of 1,3-Dihydroxy-2-Methylanthraquinone and the Ethyl Acetate Fraction of Hedyotis Diffusa Willd against HepG2 Carcinoma Cells Mediated via Apoptosis. PloS one. 2016; 11(4):e0151502. doi: 10.1371/journal.pone.0151502. [PMID: 27064569]
  • Meng Qiao, Weixiao Qi, Huijuan Liu, Jiuhui Qu. Occurrence, behavior and removal of typical substituted and parent polycyclic aromatic hydrocarbons in a biological wastewater treatment plant. Water research. 2014 Apr; 52(?):11-9. doi: 10.1016/j.watres.2013.12.032. [PMID: 24440761]
  • Chi-Sheng Shia, Yu-Chi Hou, Shin-Hun Juang, Shang-Yuan Tsai, Pei-Hsun Hsieh, Lu-Ching Ho, Pei-Dawn Lee Chao. Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. Evidence-based complementary and alternative medicine : eCAM. 2011; 2011(?):721293. doi: 10.1093/ecam/nep124. [PMID: 19737807]
  • Sen-Sung Cheng, Chin-Gi Huang, Wei-June Chen, Yueh-Hsiung Kuo, Shang-Tzen Chang. Larvicidal activity of tectoquinone isolated from red heartwood-type Cryptomeria japonica against two mosquito species. Bioresource technology. 2008 Jun; 99(9):3617-22. doi: 10.1016/j.biortech.2007.07.038. [PMID: 17804221]
  • Pittaya Tuntiwachwuttikul, Yuttapon Butsuri, Piyanut Sukkoet, Uma Prawat, Walter Charles Taylor. Anthraquinones from the roots of Prismatomeris malayana. Natural product research. 2008; 22(11):962-8. doi: 10.1080/14786410701650261. [PMID: 18629711]
  • Pattarawadee Sumthong, Robbert A Damveld, Young H Choi, Mark Arentshorst, Arthur F Ram, Cees A van den Hondel, Rob Verpoorte. Activity of quinones from teak (Tectona grandis) on fungal cell wall stress. Planta medica. 2006 Aug; 72(10):943-4. doi: 10.1055/s-2006-946676. [PMID: 16972200]
  • Man-Yuan Wang, Lan Yang, You-You Tu. [Studies on the chemical constituents from stem of Chirita longgangensis var. Hongyao]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Feb; 31(4):307-8. doi: . [PMID: 16706021]
  • Kenneth Oben Eyong, Karsten Krohn, Hidayat Hussain, Gabriel Ngosong Folefoc, Augustin Ephram Nkengfack, Barbara Schulz, Qunxiu Hu. Newbouldiaquinone and newbouldiamide: a new naphthoquinone-anthraquinone coupled pigment and a new ceramide from Newbouldia laevis. Chemical & pharmaceutical bulletin. 2005 Jun; 53(6):616-9. doi: 10.1248/cpb.53.616. [PMID: 15930769]
  • Seru Ganapaty, Pannakal Steve Thomas, Serge Fotso, Hartmut Laatsch. Antitermitic quinones from Diospyros sylvatica. Phytochemistry. 2004 May; 65(9):1265-71. doi: 10.1016/j.phytochem.2004.03.011. [PMID: 15184011]
  • Samir El-Hady, Jacques Bukuru, Bart Kesteleyn, Luc Van Puyvelde, Tuyen Nguyen Van, Norbert De Kimpe. New pyranonaphthoquinone and pyranonaphthohydroquinone from the roots of Pentas longiflora. Journal of natural products. 2002 Sep; 65(9):1377-9. doi: 10.1021/np020110e. [PMID: 12350172]
  • S Li, Q Ouyang, X Tan, S Shi, Z Yao. [Chemical constituents of Morinda officinalis How]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1991 Nov; 16(11):675-6, 703. doi: . [PMID: 1804172]
  • M Sano. Subcellular localizations of guanylate cyclase and 3',5'-cyclic nucleotide phosphodiesterase in sea urchin sperm. Biochimica et biophysica acta. 1976 Apr; 428(2):525-31. doi: 10.1016/0304-4165(76)90061-1. [PMID: 6049]