Phenylethyl alcohol (BioDeep_00000395755)

Chemicals and Drugs

代谢物信息卡片

Phenylethyl alcohol

化学式: C8H10O (122.07316100000001)
中文名称: 2-苯乙醇, 苯乙醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)CCO
InChI: InChI=1S/C8H10O/c9-7-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2

描述信息

C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
D000890 - Anti-Infective Agents
D010592 - Pharmaceutic Aids
D004202 - Disinfectants
2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[1]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.
2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[1]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

同义名列表

4 个代谢物同义名

Phenylethyl alcohol; 2-Phenylethanol; Phenethyl alcohol; Benzyl carbinol

数据库引用编号

17 个数据库交叉引用编号

ChEBI: CHEBI:49000
KEGG: C05853
KEGGdrug: D70868
KEGGdrug: D00192
PubChem: 6054
DrugBank: DB02192
ChEMBL: CHEMBL448500
MeSH: Phenylethyl Alcohol
CAS: 19601-20-8
CAS: 1321-27-3
CAS: 60-12-8
medchemexpress: HY-B1290
PubChem: 8146
KNApSAcK: C00002663
PDB-CCD: PEL
3DMET: B00869
NIKKAJI: J1.924K

分类词条

抗生素

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

254 个相关的物种来源信息

1078594 Erucaria microcarpa: 10.1002/(SICI)1099-1573(199906)13:4<329::AID-PTR458>3.0.CO;2-U
180772 Vaccinium vitis-idaea: 10.3891/ACTA.CHEM.SCAND.21-0945
329675 Daphne odora: 10.1271/BBB1961.47.483
2715869 Daphne papyracea: 10.1271/BBB1961.47.483
200489 Saussurea involucrata: 10.1080/10412905.1992.9698080
225107 Karenia mikimotoi: 10.1016/0031-9422(92)80160-G
671128 Gymnodinium nagasakiense: 10.1016/0031-9422(92)80160-G
547782 Symphyotrichum undulatum: 10.1021/JF00034A033
385370 Aster scaber: 10.1021/JF00034A033
114816 Castanopsis cuspidata: 10.1021/JF60224A025
328070 Dactylanthus taylorii: 10.1016/0031-9422(95)00403-T
74632 Rosa gallica:
29760 Vitis vinifera:
65409 Scutellaria baicalensis: 10.1271/BBB1961.51.1449
62097 Plumeria rubra:
3760 Prunus persica: 10.1021/JF00004A032
36596 Prunus armeniaca: 10.1021/JF00004A032
3758 Prunus domestica: 10.1021/JF00004A032
1392 Bacillus anthracis: 10.1038/S41598-020-66136-0
263 Francisella tularensis: 10.1038/S41598-020-66136-0
35924 Paeonia lactiflora:
3750 Malus domestica: 10.1021/JF00025A025
283210 Malus pumila: 10.1021/JF00025A025
3654 Citrullus lanatus: 10.1271/BBB1961.49.3145
334483 Syzygium jambos: 10.1080/10412905.1991.9697916
128608 Cinnamomum verum: 10.1021/JF60218A031
265416 Solanum stuckertii: 10.1080/10412905.1997.9700728
118700 Nicotiana langsdorffii: 10.1016/J.PHYTOCHEM.2006.05.038
118694 Nicotiana bonariensis: 10.1016/J.PHYTOCHEM.2006.05.038
85571 Citrus reticulata: 10.1016/J.PHYTOCHEM.2009.07.031
558547 Citrus deliciosa: 10.1016/J.PHYTOCHEM.2009.07.031
170989 Citrus hystrix: 10.1016/J.PHYTOCHEM.2009.07.031
3589 Basella alba: 10.1016/0889-1575(91)90017-Z
3635 Gossypium hirsutum: 10.1021/JF60200A011
49827 Glycyrrhiza glabra:
50282 Centaurea benedicta: 10.1055/S-0028-1099484
16719 Juglans nigra:
41492 Bellis perennis: 10.1016/0031-9422(95)00183-8
39338 Melissa officinalis:
39367 Salvia rosmarinus: 10.3390/MOLECULES21111576
146781 Phallus impudicus:
4463 Sauromatum venosum: 10.1016/S0031-9422(00)94756-3
260595 Cedronella canariensis: 10.1016/0031-9422(95)00241-X
3755 Prunus dulcis: 10.1021/JF60228A025
155124 Aspalathus linearis: 10.1021/JF00062A024
174549 Polygala senega: 10.1002/FFJ.2730100408
3039 Euglena gracilis: 10.3389/FBIOE.2021.662655
105884 Lonicera japonica: 10.1021/JF950275B
137129 Swertia japonica: 10.1246/BCSJ.56.3477
282714 Achillea abrotanoides: 10.1016/0305-1978(92)90070-T
114280 Cichorium endivia: 10.1021/JF00068A014
103349 Vitis rotundifolia:
45171 Paeonia suffruticosa: 10.1080/00021369.1983.10866058
3641 Theobroma cacao: 10.1021/JF60160A011
118778 Tussilago farfara: 10.1248/YAKUSHI1947.112.8_571
136225 Zingiber mioga: 10.1271/BBB1961.55.1655
50172 Viscum articulatum: 10.1248/CPB.52.858
4442 Camellia sinensis:
55982 Ips cembrae: 10.1007/S000490050010
226899 Grosmannia clavigera: 10.1139/V86-149
4926 Pichia membranifaciens: 10.1021/NP070605+
3879 Medicago sativa: 10.1016/S0031-9422(97)00119-2
4577 Zea mays: 10.1021/JF60220A012
265783 Artemisia capillaris: 10.1055/S-2005-837790
48027 Anthriscus sylvestris: 10.1248/YAKUSHI1947.99.6_602
13750 Vaccinium macrocarpon: 10.3891/ACTA.CHEM.SCAND.21-2076
127999 Tanacetum parthenium: 10.1007/S004030050433
33171 Eremothecium ashbyi: 10.1007/BF00598377
145953 Ophrys sphegodes: 10.1016/S0031-9422(00)81276-5
33169 Eremothecium gossypii: 10.1007/BF00630334
313948 Rhanterium epapposum: 10.1002/FFJ.2730020106
205076 Vachellia rigidula: 10.1021/JF00120A008
35938 Robinia pseudoacacia: 10.1039/AN9285300411
13393 Cananga odorata: 10.1021/JF00069A028
4081 Solanum lycopersicum: 10.1021/JF00014A016
119949 Myrtus communis:
43982 Ambrosiozyma monospora: 10.1055/S-2007-969476
1807033 Phomopsis velata: 10.1016/S0031-9422(00)83157-X
5791 Physarum polycephalum: 10.1248/CPB.32.797
203015 Rhodiola rosea: 10.1016/S0031-9422(02)00004-3
3728 Sinapis alba: 10.1016/J.PHYTOCHEM.2006.12.009
264418 Hesperis matronalis:
3707 Brassica juncea: 10.1016/0031-9422(88)83085-1
3710 Brassica nigra: 10.1016/0031-9422(88)83085-1
3708 Brassica napus: 10.1016/0031-9422(88)83085-1
3711 Brassica rapa: 10.1016/0031-9422(88)83085-1
492000 Decalepis hamiltonii: 10.1002/1099-1026(200101/02)16:1<27::AID-FFJ937>3.0.CO;2-F
42337 Bidens pilosa: 10.1002/JCCS.200000152
49558 Osmorhiza aristata: 10.1248/YAKUSHI1947.99.11_1116
222877 Phyla nodiflora: 10.1021/NP50039A037
53737 Sphagneticola trilobata: 10.1002/FFJ.3227
64042 Actaea simplex: 10.1016/0305-1978(87)90058-5
39324 Hyssopus officinalis: 10.1002/FFJ.2730060109
2849048 Lucensosergia lucens: 10.1080/00021369.1984.10866348
589641 Sergia lucens: 10.1080/00021369.1984.10866348
483693 Inula racemosa: 10.1016/S0031-9422(00)83760-7
38033 Chaetomium globosum:
57577 Trifolium pratense: 10.1021/JF00122A019
204156 Platostoma africanum: 10.1055/S-2006-962093
39333 Lavandula stoechas: 10.1016/0305-1978(96)00023-3
97307 Prunus padus: 10.1080/10412905.1990.9697889
501610 Agathosma betulina: 10.1021/JF60201A021
175730 Amorphophallus eichleri: 10.1016/S0031-9422(97)00221-5
28974 Averrhoa carambola: 10.1021/JF00062A009
63704 Gonioctena viminalis: 10.1007/BF01940454
78388 Coniothyrium: 10.1021/NP980341E
125157 Peristeria elata: 10.1080/10412905.1992.9698106
5061 Aspergillus niger: 10.1016/0031-9422(88)80021-9
73824 Populus balsamifera: 10.1515/ZNC-1989-5-603
1616482 Populus candicans: 10.1515/ZNC-1989-5-603
4265 Cynara cardunculus: 10.1016/S0031-9422(82)85033-4
67295 Streptomyces fimicarius: 10.1155/2018/4823126
124943 Azadirachta indica: 10.1016/0010-7824(90)90054-Y
140311 Prunus cerasus: 10.1016/0031-9422(90)85126-Z
373155 Gaillardia aestivalis: 10.1016/S0031-9422(00)95216-6
60009 Populus ciliata: 10.1016/0031-9422(91)85033-V
4565 Triticum aestivum: 10.1021/JF0204755
159425 Passiflora incarnata: 10.1080/10412905.1992.9698081
660624 Jasminum sambac: 10.1271/BBB.57.1101
114476 Gardenia jasminoides: 10.1271/BBB.57.1101
85216 Jasminum polyanthum: 10.1271/BBB.57.1101
5482 Candida tropicalis: 10.1007/BF00988116
40698 Paeonia anomala: 10.1007/BF00629664
169388 Fusarium solani: 10.1016/0031-9422(88)80051-7
4956 Zygosaccharomyces rouxii: 10.1271/BBB1961.54.273
1078594 Erucaria microcarpa: 10.1002/(SICI)1099-1573(199906)13:4<329::AID-PTR458>3.0.CO;2-U
180772 Vaccinium vitis-idaea: 10.3891/ACTA.CHEM.SCAND.21-0945
329675 Daphne odora: 10.1271/BBB1961.47.483
2715869 Daphne papyracea: 10.1271/BBB1961.47.483
200489 Saussurea involucrata: 10.1080/10412905.1992.9698080
225107 Karenia mikimotoi: 10.1016/0031-9422(92)80160-G
671128 Gymnodinium nagasakiense: 10.1016/0031-9422(92)80160-G
547782 Symphyotrichum undulatum: 10.1021/JF00034A033
385370 Aster scaber: 10.1021/JF00034A033
114816 Castanopsis cuspidata: 10.1021/JF60224A025
328070 Dactylanthus taylorii: 10.1016/0031-9422(95)00403-T
74632 Rosa gallica:
29760 Vitis vinifera:
65409 Scutellaria baicalensis: 10.1271/BBB1961.51.1449
62097 Plumeria rubra:
3760 Prunus persica: 10.1021/JF00004A032
36596 Prunus armeniaca: 10.1021/JF00004A032
3758 Prunus domestica: 10.1021/JF00004A032
1392 Bacillus anthracis: 10.1038/S41598-020-66136-0
263 Francisella tularensis: 10.1038/S41598-020-66136-0
35924 Paeonia lactiflora:
3750 Malus domestica: 10.1021/JF00025A025
283210 Malus pumila: 10.1021/JF00025A025
3654 Citrullus lanatus: 10.1271/BBB1961.49.3145
334483 Syzygium jambos: 10.1080/10412905.1991.9697916
128608 Cinnamomum verum: 10.1021/JF60218A031
265416 Solanum stuckertii: 10.1080/10412905.1997.9700728
118700 Nicotiana langsdorffii: 10.1016/J.PHYTOCHEM.2006.05.038
118694 Nicotiana bonariensis: 10.1016/J.PHYTOCHEM.2006.05.038
85571 Citrus reticulata: 10.1016/J.PHYTOCHEM.2009.07.031
558547 Citrus deliciosa: 10.1016/J.PHYTOCHEM.2009.07.031
170989 Citrus hystrix: 10.1016/J.PHYTOCHEM.2009.07.031
3589 Basella alba: 10.1016/0889-1575(91)90017-Z
3635 Gossypium hirsutum: 10.1021/JF60200A011
49827 Glycyrrhiza glabra:
50282 Centaurea benedicta: 10.1055/S-0028-1099484
16719 Juglans nigra:
41492 Bellis perennis: 10.1016/0031-9422(95)00183-8
39338 Melissa officinalis:
39367 Salvia rosmarinus: 10.3390/MOLECULES21111576
146781 Phallus impudicus:
4463 Sauromatum venosum: 10.1016/S0031-9422(00)94756-3
260595 Cedronella canariensis: 10.1016/0031-9422(95)00241-X
3755 Prunus dulcis: 10.1021/JF60228A025
155124 Aspalathus linearis: 10.1021/JF00062A024
174549 Polygala senega: 10.1002/FFJ.2730100408
3039 Euglena gracilis: 10.3389/FBIOE.2021.662655
105884 Lonicera japonica: 10.1021/JF950275B
137129 Swertia japonica: 10.1246/BCSJ.56.3477
282714 Achillea abrotanoides: 10.1016/0305-1978(92)90070-T
114280 Cichorium endivia: 10.1021/JF00068A014
103349 Vitis rotundifolia:
45171 Paeonia suffruticosa: 10.1080/00021369.1983.10866058
3641 Theobroma cacao: 10.1021/JF60160A011
118778 Tussilago farfara: 10.1248/YAKUSHI1947.112.8_571
136225 Zingiber mioga: 10.1271/BBB1961.55.1655
50172 Viscum articulatum: 10.1248/CPB.52.858
4442 Camellia sinensis:
55982 Ips cembrae: 10.1007/S000490050010
226899 Grosmannia clavigera: 10.1139/V86-149
4926 Pichia membranifaciens: 10.1021/NP070605+
3879 Medicago sativa: 10.1016/S0031-9422(97)00119-2
4577 Zea mays: 10.1021/JF60220A012
265783 Artemisia capillaris: 10.1055/S-2005-837790
48027 Anthriscus sylvestris: 10.1248/YAKUSHI1947.99.6_602
13750 Vaccinium macrocarpon: 10.3891/ACTA.CHEM.SCAND.21-2076
127999 Tanacetum parthenium: 10.1007/S004030050433
33171 Eremothecium ashbyi: 10.1007/BF00598377
145953 Ophrys sphegodes: 10.1016/S0031-9422(00)81276-5
33169 Eremothecium gossypii: 10.1007/BF00630334
313948 Rhanterium epapposum: 10.1002/FFJ.2730020106
205076 Vachellia rigidula: 10.1021/JF00120A008
35938 Robinia pseudoacacia: 10.1039/AN9285300411
13393 Cananga odorata: 10.1021/JF00069A028
4081 Solanum lycopersicum: 10.1021/JF00014A016
119949 Myrtus communis:
43982 Ambrosiozyma monospora: 10.1055/S-2007-969476
1807033 Phomopsis velata: 10.1016/S0031-9422(00)83157-X
5791 Physarum polycephalum: 10.1248/CPB.32.797
203015 Rhodiola rosea: 10.1016/S0031-9422(02)00004-3
3728 Sinapis alba: 10.1016/J.PHYTOCHEM.2006.12.009
264418 Hesperis matronalis:
3707 Brassica juncea: 10.1016/0031-9422(88)83085-1
3710 Brassica nigra: 10.1016/0031-9422(88)83085-1
3708 Brassica napus: 10.1016/0031-9422(88)83085-1
3711 Brassica rapa: 10.1016/0031-9422(88)83085-1
492000 Decalepis hamiltonii: 10.1002/1099-1026(200101/02)16:1<27::AID-FFJ937>3.0.CO;2-F
42337 Bidens pilosa: 10.1002/JCCS.200000152
49558 Osmorhiza aristata: 10.1248/YAKUSHI1947.99.11_1116
222877 Phyla nodiflora: 10.1021/NP50039A037
53737 Sphagneticola trilobata: 10.1002/FFJ.3227
64042 Actaea simplex: 10.1016/0305-1978(87)90058-5
39324 Hyssopus officinalis: 10.1002/FFJ.2730060109
2849048 Lucensosergia lucens: 10.1080/00021369.1984.10866348
589641 Sergia lucens: 10.1080/00021369.1984.10866348
483693 Inula racemosa: 10.1016/S0031-9422(00)83760-7
38033 Chaetomium globosum:
57577 Trifolium pratense: 10.1021/JF00122A019
204156 Platostoma africanum: 10.1055/S-2006-962093
39333 Lavandula stoechas: 10.1016/0305-1978(96)00023-3
97307 Prunus padus: 10.1080/10412905.1990.9697889
501610 Agathosma betulina: 10.1021/JF60201A021
175730 Amorphophallus eichleri: 10.1016/S0031-9422(97)00221-5
28974 Averrhoa carambola: 10.1021/JF00062A009
63704 Gonioctena viminalis: 10.1007/BF01940454
78388 Coniothyrium: 10.1021/NP980341E
125157 Peristeria elata: 10.1080/10412905.1992.9698106
5061 Aspergillus niger: 10.1016/0031-9422(88)80021-9
73824 Populus balsamifera: 10.1515/ZNC-1989-5-603
1616482 Populus candicans: 10.1515/ZNC-1989-5-603
4265 Cynara cardunculus: 10.1016/S0031-9422(82)85033-4
67295 Streptomyces fimicarius: 10.1155/2018/4823126
124943 Azadirachta indica: 10.1016/0010-7824(90)90054-Y
140311 Prunus cerasus: 10.1016/0031-9422(90)85126-Z
373155 Gaillardia aestivalis: 10.1016/S0031-9422(00)95216-6
60009 Populus ciliata: 10.1016/0031-9422(91)85033-V
4565 Triticum aestivum: 10.1021/JF0204755
159425 Passiflora incarnata: 10.1080/10412905.1992.9698081
660624 Jasminum sambac: 10.1271/BBB.57.1101
114476 Gardenia jasminoides: 10.1271/BBB.57.1101
85216 Jasminum polyanthum: 10.1271/BBB.57.1101
5482 Candida tropicalis: 10.1007/BF00988116
40698 Paeonia anomala: 10.1007/BF00629664
169388 Fusarium solani: 10.1016/0031-9422(88)80051-7
4956 Zygosaccharomyces rouxii: 10.1271/BBB1961.54.273
569774 金线莲: -
201509 Gmelina arborea: -
4432 Nelumbo nucifera: -
33090 Plants: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Ying Lu, Luyan Gao, Wenwen Zhang, Ying Zeng, Ji Hu, Kai Song. Caffeic acid phenethyl ester restores mitochondrial homeostasis against peritoneal fibrosis induced by peritoneal dialysis through the AMPK/SIRT1 pathway. Renal failure. 2024 Dec; 46(1):2350235. doi: 10.1080/0886022x.2024.2350235. [PMID: 38721924]
Vinayak Laxman Pachapur, Mariana Valdez Castillo, Rahul Saini, Satinder Kaur Brar, Yann Le Bihan. Integrated biorefinery approach for utilization of wood waste into levulinic acid and 2-Phenylethanol production under mild treatment conditions. Journal of biotechnology. 2024 Jun; 389(?):78-85. doi: 10.1016/j.jbiotec.2024.05.002. [PMID: 38718873]
Adam J Lewis, Amanda C Richards, Alejandra A Mendez, Bijaya K Dhakal, Tiffani A Jones, Jamie L Sundsbak, Danelle S Eto, Alexis A Rousek, Matthew A Mulvey. Plant phenolics inhibit focal adhesion kinase and suppress host cell invasion by uropathogenic Escherichia coli. Infection and immunity. 2024 May; 92(5):e0008024. doi: 10.1128/iai.00080-24. [PMID: 38534100]
Li Fan, Lijuan Zhao, Yangbo Zhu, Lin Li, Xueping Yang, Ping Ma, Jian Liu, Qingwei Zhao, Xiaobo Li. Hydroxytyrosol ameliorates stress-induced liver injury through activating autophagy via HDAC1/2 inhibition. Food & function. 2024 May; 15(9):5103-5117. doi: 10.1039/d4fo01027b. [PMID: 38680105]
Zhanding Cui, Jing Zhang, Jinlong Wang, Jinlong Liu, Pu Sun, Jiaoyang Li, Guoxiu Li, Ying Sun, Juanbin Ying, Kun Li, Zhixun Zhao, Hong Yuan, Xingwen Bai, Xueqing Ma, Pinghua Li, Yuanfang Fu, Huifang Bao, Dong Li, Qiang Zhang, Zaixin Liu, Yimei Cao, Zengjun Lu. Caffeic acid phenethyl ester: an effective antiviral agent against porcine reproductive and Respiratory Syndrome Virus. Antiviral research. 2024 May; 225(?):105868. doi: 10.1016/j.antiviral.2024.105868. [PMID: 38490343]
Qizhen Cui, Qingqing Liu, Yutong Fan, Chenhe Wang, Yufei Li, Shuyuan Li, Jianguo Zhang, Guodong Rao. Functional differentiation of olive PLP_deC genes: insights into metabolite biosynthesis and genetic improvement at the whole-genome level. Plant cell reports. 2024 Apr; 43(5):127. doi: 10.1007/s00299-024-03212-z. [PMID: 38652203]
Daniela Gabbia, Katia Sayaf, Ilaria Zanotto, Martina Colognesi, Yahima Frion-Herrera, Maria Carrara, Francesco Paolo Russo, Sara De Martin. Tyrosol attenuates NASH features by reprogramming the hepatic immune milieu. European journal of pharmacology. 2024 Apr; 969(?):176453. doi: 10.1016/j.ejphar.2024.176453. [PMID: 38408597]
Yu Wang, Jihang Hou, Xiaoping Li, Pan Chen, Fang Chen, Yao Pan, Zeyuan Deng, Jing Li, Rong Liu, Ting Luo. Tyrosol regulates hepatic lipid metabolism in high-fat diet-induced NAFLD mice. Food & function. 2024 Apr; 15(7):3752-3764. doi: 10.1039/d3fo05345h. [PMID: 38506160]
Guosi Li, Wei Wang, Heng Guo, Shanyong Yi, Fang Wang, Shiping Huang, Nan Hu, Qilin Xu, Yongjun Zang, Bangxing Han, Xinjian Yin. Mutability landscape guided engineering of a promiscuous microbial glycosyltransferase for regioselective synthesis of salidroside and icariside D2. International journal of biological macromolecules. 2024 Apr; 263(Pt 1):130229. doi: 10.1016/j.ijbiomac.2024.130229. [PMID: 38378110]
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Jiaojiao Yuan, Su Tuo, Xiuhong Shi, Junling Tu. A new combined technology: Macroporous adsorption resin and high speed counter current chromatography for hydroxytyrosol separation from olive leaf enzymatic hydrolysate. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2024 Mar; 1235(?):124058. doi: 10.1016/j.jchromb.2024.124058. [PMID: 38394917]
Mojtaba Baharsaadi, Maryam Hezavehei, Abdolhossein Shahverdi, Iman Halvaei. Evaluation of the effects of hydroxytyrosol on human sperm parameters during cryopreservation. Cryobiology. 2024 03; 114(?):104840. doi: 10.1016/j.cryobiol.2023.104840. [PMID: 38104853]
Regina Viana de Carvalho Faria, Matheus Silva Duarte, Jeane de Souza Nogueira, Bianca Martins Gregório, Bruna Romana-Souza. Nrf2 activation by hydroxytyrosol and dimethyl fumarate ameliorates skin tissue repair in high-fat diet-fed mice by promoting M2 macrophage polarization and normalizing inflammatory response and oxidative damage. Journal of biochemical and molecular toxicology. 2024 Feb; 38(2):e23652. doi: 10.1002/jbt.23652. [PMID: 38348708]
Anabel González-Acedo, Rebeca Illescas-Montes, Elvira de Luna-Bertos, Concepción Ruiz, Javier Ramos-Torrecillas, Olga García-Martínez, Lucía Melguizo-Rodríguez. Extra Virgin Olive Oil Phenolic Compounds Modulate the Gene Expression of Biomarkers Involved in Fibroblast Proliferation and Differentiation. Genes. 2024 Jan; 15(2):. doi: 10.3390/genes15020173. [PMID: 38397163]
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Xiangru Zhou, Fushuai Gong, Jiawei Dong, Xiaoru Lin, Kun Cao, Hongwei Xu, Xiaofu Zhou. Abscisic Acid Affects Phenolic Acid Content to Increase Tolerance to UV-B Stress in Rhododendron chrysanthum Pall. International journal of molecular sciences. 2024 Jan; 25(2):. doi: 10.3390/ijms25021234. [PMID: 38279235]
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Maria Kourti, Zoi Skaperda, Fotios Tekos, Panagiotis Stathopoulos, Christina Koutra, Alexios Leandros Skaltsounis, Demetrios Kouretas. The Bioactivity of a Hydroxytyrosol-Enriched Extract Originated after Direct Hydrolysis of Olive Leaves from Greek Cultivars. Molecules (Basel, Switzerland). 2024 Jan; 29(2):. doi: 10.3390/molecules29020299. [PMID: 38257212]
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Guoqing Zhang, Yu Fu, Yikang Shao, Jing Zhao, Xin Lei, Yueguan Fu, Lei Li, Aiming Zhou. Semiochemicals Produced by Microbes in Mealybug Honeydew Attract Fire Ants. Journal of agricultural and food chemistry. 2023 Oct; 71(42):15456-15465. doi: 10.1021/acs.jafc.3c04444. [PMID: 37843466]
Munmun Kumar Singh, Kumari Savita, Swati Singh, Divya Mishra, Poonam Rani, Debabrata Chanda, Ram Swaroop Verma. Vasorelaxant property of 2-phenyl ethyl alcohol isolated from the spent floral distillate of damask rose (Rosa damascena Mill.) and its possible mechanism. Journal of ethnopharmacology. 2023 Sep; 313(?):116603. doi: 10.1016/j.jep.2023.116603. [PMID: 37149069]
Junming Sun, Kexin Tian, Lu Jing, Yafei Niu, Qian Lou, Hongwu Chen. Identification of characteristic aroma compounds for spicy in Iris lactea var. chinensis. Physiologia plantarum. 2023 Sep; 175(5):e14016. doi: 10.1111/ppl.14016. [PMID: 37882258]
Xiang Li, Denise Tieman, Saleh Alseekh, Alisdair R Fernie, Harry J Klee. Natural variations in the Sl-AKR9 aldo/keto reductase gene impact fruit flavor volatile and sugar contents. The Plant journal : for cell and molecular biology. 2023 May; ?(?):. doi: 10.1111/tpj.16310. [PMID: 37243881]
Qi Jia, Pei-Yuan Yang, Ya-Ling Li, Guo-Dong Yao, Shao-Jiang Song, Xiao-Xiao Huang. Two New Enantiomers of Phenylethanoid and Their Anti-Inflammatory Activities. Chemistry & biodiversity. 2023 Apr; 20(4):e202300067. doi: 10.1002/cbdv.202300067. [PMID: 36810976]
Rong-San Jiang, Karen Yan, Yi-Fang Chiang, Pei-Jung Chiang. The Effect of Chinese Herbal Medicine on Traumatic Anosmia: A Prospective, Randomized Clinical Trial. The Laryngoscope. 2023 Mar; ?(?):. doi: 10.1002/lary.30676. [PMID: 36960884]
Ubashini Vijakumaran, Janushaa Shanmugam, Jun Wei Heng, Siti Sarah Azman, Muhammad Dain Yazid, Nur Atiqah Haizum Abdullah, Nadiah Sulaiman. Effects of Hydroxytyrosol in Endothelial Functioning: A Comprehensive Review. Molecules (Basel, Switzerland). 2023 Feb; 28(4):. doi: 10.3390/molecules28041861. [PMID: 36838850]
Shuang Liang, Fang Wang, Daniel Granato, Xiaoyu Zhong, An-Feng Xiao, Qun Ye, Lijun Li, Chun Zou, Jun-Feng Yin, Yong-Quan Xu. Effect of β-glucosidase on the aroma of liquid-fermented black tea juice as an ingredient for tea-based beverages. Food chemistry. 2023 Feb; 402(?):134201. doi: 10.1016/j.foodchem.2022.134201. [PMID: 36122474]
Yangyang Zhan, Haixia Xu, Hween Tong Tan, Ying Swan Ho, Dongxiao Yang, Shuwen Chen, Dave Siak-Wei Ow, Xin Lv, Fang Wei, Xuezhi Bi, Shouwen Chen. Systematic Adaptation of Bacillus licheniformis to 2-Phenylethanol Stress. Applied and environmental microbiology. 2023 Feb; ?(?):e0156822. doi: 10.1128/aem.01568-22. [PMID: 36752618]
Monica Nardi, Steve Brocchini, Satyanarayana Somavarapu, Antonio Procopio. Hydroxytyrosol oleate: A promising neuroprotective nanocarrier delivery system of oleuropein and derivatives. International journal of pharmaceutics. 2023 Jan; 631(?):122498. doi: 10.1016/j.ijpharm.2022.122498. [PMID: 36535454]
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Bahrie Ramadan, Lidia Cabeza, Stéphanie Cramoisy, Christophe Houdayer, Patrice Andrieu, Jean-Louis Millot, Emmanuel Haffen, Pierre-Yves Risold, Yvan Peterschmitt. Beneficial effects of prolonged 2-phenylethyl alcohol inhalation on chronic distress-induced anxio-depressive-like phenotype in female mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Jul; 151(?):113100. doi: 10.1016/j.biopha.2022.113100. [PMID: 35597115]
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Halil Sezgin Semis, Cihan Gur, Mustafa Ileriturk, Ozgur Kaynar, Fatih Mehmet Kandemir. Investigation of the anti-inflammatory effects of caffeic acid phenethyl ester in a model of λ-Carrageenan-induced paw edema in rats. Human & experimental toxicology. 2021 Dec; 40(12_suppl):S721-S738. doi: 10.1177/09603271211054436. [PMID: 34789018]
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Shu-Shong Hsu, Yung-Shang Lin, Wei-Zhe Liang. Inhibition of the pesticide rotenone-induced Ca2+ signaling, cytotoxicity and oxidative stress in HCN-2 neuronal cells by the phenolic compound hydroxytyrosol. Pesticide biochemistry and physiology. 2021 Nov; 179(?):104979. doi: 10.1016/j.pestbp.2021.104979. [PMID: 34802529]
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Nikolaos Katsinas, Amalia Enríquez-de-Salamanca, Andreia Bento da Silva, Maria Rosário Bronze, Soraya Rodríguez-Rojo. Olive Pomace Phenolic Compounds Stability and Safety Evaluation: From Raw Material to Future Ophthalmic Applications. Molecules (Basel, Switzerland). 2021 Oct; 26(19):. doi: 10.3390/molecules26196002. [PMID: 34641545]
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Ramasamy Chandramohan, Leelavinothan Pari. Antihyperlipidemic effect of tyrosol, a phenolic compound in streptozotocin-induced diabetic rats. Toxicology mechanisms and methods. 2021 Sep; 31(7):507-516. doi: 10.1080/15376516.2021.1926030. [PMID: 33942700]
Rajashri R Naik, Ashok K Shakya, Ghaleb A Oriquat, Shankar Katekhaye, Anant Paradkar, Hugo Fearnley, James Fearnley. Fatty Acid Analysis, Chemical Constituents, Biological Activity and Pesticide Residues Screening in Jordanian Propolis. Molecules (Basel, Switzerland). 2021 Aug; 26(16):. doi: 10.3390/molecules26165076. [PMID: 34443664]
Rosario Pastor, Cristina Bouzas, Josep A Tur. Beneficial effects of dietary supplementation with olive oil, oleic acid, or hydroxytyrosol in metabolic syndrome: Systematic review and meta-analysis. Free radical biology & medicine. 2021 08; 172(?):372-385. doi: 10.1016/j.freeradbiomed.2021.06.017. [PMID: 34153478]
Elisa Pannucci, Rocco Caracciolo, Annalisa Romani, Francesco Cacciola, Paola Dugo, Roberta Bernini, Leonardo Varvaro, Luca Santi. An hydroxytyrosol enriched extract from olive mill wastewaters exerts antioxidant activity and antimicrobial activity on Pseudomonas savastanoi pv. savastanoi and Agrobacterium tumefaciens. Natural product research. 2021 Aug; 35(16):2677-2684. doi: 10.1080/14786419.2019.1662006. [PMID: 31496275]
Halil Ibrahim Guler, Gizem Tatar, Oktay Yildiz, Ali Osman Belduz, Sevgi Kolayli. Investigation of potential inhibitor properties of ethanolic propolis extracts against ACE-II receptors for COVID-19 treatment by molecular docking study. Archives of microbiology. 2021 Aug; 203(6):3557-3564. doi: 10.1007/s00203-021-02351-1. [PMID: 33950349]
Aurélia Malapert, Emmanuelle Reboul, Olivier Dangles, Alain Thiéry, N'nabinty Sylla, Valérie Tomao. One-Step Extraction of Olive Phenols from Aqueous Solution Using β-Cyclodextrin in the Solid State, a Simple Eco-Friendly Method Providing Photochemical Stability to the Extracts. Molecules (Basel, Switzerland). 2021 Jul; 26(15):. doi: 10.3390/molecules26154463. [PMID: 34361616]
Limei Wen, Junping Hu, Jiawei Zhang, Jianhua Yang. Phenylethanol glycosides from Herba Cistanche improve the hypoxic tumor microenvironment and enhance the effects of oxaliplatin via the HIF‑1α signaling pathway. Molecular medicine reports. 2021 07; 24(1):. doi: 10.3892/mmr.2021.12156. [PMID: 34013363]
Chen Chen, Qidi Ai, Yuhui Wei. Hydroxytyrosol protects against cisplatin-induced nephrotoxicity via attenuating CKLF1 mediated inflammation, and inhibiting oxidative stress and apoptosis. International immunopharmacology. 2021 Jul; 96(?):107805. doi: 10.1016/j.intimp.2021.107805. [PMID: 34162164]
Camila Macaúbas-Silva, Maysa D G Félix, Ana Karoline S de Aquino, Paulo G Pereira-Júnior, Emmily Vieira de O Brito, Abrahão A de Oliveira-Filho, John O Igoli, David G Watson, Yanna C F Teles. Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw. Natural product research. 2021 Jul; 35(14):2424-2428. doi: 10.1080/14786419.2019.1672683. [PMID: 31581838]
Vipul Kumar, Jaspreet Kaur Dhanjal, Sunil C Kaul, Renu Wadhwa, Durai Sundar. Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity. Journal of biomolecular structure & dynamics. 2021 07; 39(11):3842-3854. doi: 10.1080/07391102.2020.1772108. [PMID: 32431217]
Umut Yiğit, Fatma Yeşim Kırzıoğlu, Özlem Özmen, Abdülhadi Cihangir Uğuz. Protective effects of caffeic acid phenethyl ester on the heart in experimental periodontitis against oxidative stress in rats. Dental and medical problems. 2021 Jul; 58(3):335-341. doi: 10.17219/dmp/132388. [PMID: 34597478]
Zaid Badra, Sebastian Larsson Herrera, Luca Cappellin, Franco Biasioli, Teun Dekker, Sergio Angeli, Marco Tasin. Species-Specific Induction of Plant Volatiles by Two Aphid Species in Apple: Real Time Measurement of Plant Emission and Attraction of Lacewings in the Wind Tunnel. Journal of chemical ecology. 2021 Jul; 47(7):653-663. doi: 10.1007/s10886-021-01288-5. [PMID: 34196858]
Jia Liu, Zengyuan Liu, Lili Wang, Hao He, Hailong Mu, Wenjing Sun, Yu Zhou, Yingqiu Liu, Wuren Ma, Weimin Zhang, Mingzhe Fu, Yunpeng Fan, Xiaoping Song. Bioactivity-guided isolation of immunomodulatory compounds from the fruits of Ligustrum lucidum. Journal of ethnopharmacology. 2021 Jun; 274(?):114079. doi: 10.1016/j.jep.2021.114079. [PMID: 33798661]
Sebastià Galmés, Bàrbara Reynés, Mariona Palou, Andreu Palou-March, Andreu Palou. Absorption, Distribution, Metabolism, and Excretion of the Main Olive Tree Phenols and Polyphenols: A Literature Review. Journal of agricultural and food chemistry. 2021 May; 69(18):5281-5296. doi: 10.1021/acs.jafc.1c00737. [PMID: 33908772]
Camila G Dossi, Romina G Vargas, Rodrigo Valenzuela, Luis A Videla. Beneficial effects of natural compounds on experimental liver ischemia-reperfusion injury. Food & function. 2021 May; 12(9):3787-3798. doi: 10.1039/d1fo00289a. [PMID: 33977997]
Mingzhe Li, Baoan Ning, Tianhui Wang. The mechanism and prevention of mitochondrial injury after exercise. Journal of physiology and biochemistry. 2021 May; 77(2):215-225. doi: 10.1007/s13105-021-00802-3. [PMID: 33650090]
Wei Gao, Shengdao Zheng, Eunson Hwang, Tae-Hoo Yi, Yu-Shuai Wang. Effects of phenylethanol glycosides from Orobanche cernua Loefling on UVB-Induced skin photodamage: a comparative study. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 2021 May; 20(5):599-614. doi: 10.1007/s43630-021-00038-6. [PMID: 33909279]
Emanuele Mauri, Manuele Gori, Sara Maria Giannitelli, Andrea Zancla, Pamela Mozetic, Franca Abbruzzese, Nicolò Merendino, Giuseppe Gigli, Filippo Rossi, Marcella Trombetta, Alberto Rainer. Nano-encapsulation of hydroxytyrosol into formulated nanogels improves therapeutic effects against hepatic steatosis: An in vitro study. Materials science & engineering. C, Materials for biological applications. 2021 May; 124(?):112080. doi: 10.1016/j.msec.2021.112080. [PMID: 33947572]
Mehmet Gül, Serkan Dündar, Gökhan Artaş, Akın Yiğin, Abdulsamet Tanık, Mehmet Emrah Polat, Erhan Cahit Özcan. The effect of caffeic acid phenethyl ester and Ankaferd Blood Stopper on the diabetic and nondiabetic gingival wound healing: an experimental study. Turkish journal of medical sciences. 2021 04; 51(2):848-856. doi: 10.3906/sag-2007-193. [PMID: 33244945]
Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
Shafi Mahmud, Gobindo Kumar Paul, Mirola Afroze, Shirmin Islam, Swagota Briti Ray Gupt, Mamudul Hasan Razu, Suvro Biswas, Shahriar Zaman, Md Salah Uddin, Mala Khan, Nunzio Antonio Cacciola, Talha Bin Emran, Md Abu Saleh, Raffaele Capasso, Jesus Simal-Gandara. Efficacy of Phytochemicals Derived from Avicennia officinalis for the Management of COVID-19: A Combined In Silico and Biochemical Study. Molecules (Basel, Switzerland). 2021 Apr; 26(8):. doi: 10.3390/molecules26082210. [PMID: 33921289]
Alfredo García-Layana, Sergio Recalde, Maria Hernandez, Maximino J Abraldes, João Nascimento, Emiliano Hernández-Galilea, Begoña Olmedilla-Alonso, Jose Juan Escobar-Barranco, Miguel Angel Zapata, Rufino Silva, Mariana Caballero Arredondo, María Carmen Lopez-Sabater, Silvia Mendez-Martínez, Nieves Pardiñas-Barón, Pilar Calvo, Patricia Fernández-Robredo. A Randomized Study of Nutritional Supplementation in Patients with Unilateral Wet Age-Related Macular Degeneration. Nutrients. 2021 Apr; 13(4):. doi: 10.3390/nu13041253. [PMID: 33920232]
Francesca Luzi, Elisa Pannucci, Mariangela Clemente, Edoardo Grande, Silvia Urciuoli, Annalisa Romani, Luigi Torre, Debora Puglia, Roberta Bernini, Luca Santi. Hydroxytyrosol and Oleuropein-Enriched Extracts Obtained from Olive Oil Wastes and By-Products as Active Antioxidant Ingredients for Poly (Vinyl Alcohol)-Based Films. Molecules (Basel, Switzerland). 2021 Apr; 26(7):. doi: 10.3390/molecules26072104. [PMID: 33917644]
Carolina Alemán-Jiménez, Raúl Domínguez-Perles, Sonia Medina, Iva Prgomet, Iván López-González, Agustín Simonelli-Muñoz, Maria Campillo-Cano, David Auñón, Federico Ferreres, Ángel Gil-Izquierdo. Pharmacokinetics and bioavailability of hydroxytyrosol are dependent on the food matrix in humans. European journal of nutrition. 2021 Mar; 60(2):905-915. doi: 10.1007/s00394-020-02295-0. [PMID: 32524230]
Tomoko Oshima, Michiho Ito. Sedative effects of l-menthol, d-camphor, phenylethyl alcohol, and geraniol. Journal of natural medicines. 2021 Mar; 75(2):319-325. doi: 10.1007/s11418-020-01470-1. [PMID: 33389551]
Riichi Hashimoto, Hiyori Iai, Rie Fujita, Kengo Hanaya, Shuhei Higashibayashi, Hiroyoshi Inoue, Takeshi Sugai. Chemoenzymatic semisynthesis of caffeic acid β-phenethyl ester, an antioxidative component in propolis, from raw coffee bean extract. Bioscience, biotechnology, and biochemistry. 2021 Feb; 85(3):476-480. doi: 10.1093/bbb/zbaa077. [PMID: 33624772]