Hemipyocyanine (BioDeep_00000003944)
代谢物信息卡片
化学式: C12H8N2O (196.0637)
中文名称: 1-羟基吩嗪
谱图信息:
最多检出来源 Homo sapiens(blood) 47.71%
分子结构信息
SMILES: C1=CC=C2C(=C1)N=C3C=CC=C(C3=N2)O
InChI: InChI=1S/C12H8N2O/c15-11-7-3-6-10-12(11)14-9-5-2-1-4-8(9)13-10/h1-7,15H
描述信息
CONFIDENCE standard compound; INTERNAL_ID 186
同义名列表
3 个代谢物同义名
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:62216
- KEGG: C21477
- PubChem: 135412648
- ChEMBL: CHEMBL1416045
- KNApSAcK: C00018654
- CAS: 528-71-2
- MoNA: RP018603
- MoNA: RP018602
- MoNA: RP018601
- PMhub: MS000013762
- PubChem: 329970429
- PDB-CCD: 6QF
- LOTUS: LTS0027970
- wikidata: Q27131689
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 1883 - Streptomyces: 10.1021/NP100818D
- 66431 - Streptomyces thioluteus: 10.1021/JO01287A075
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yupeng Wan, Hongchen Liu, Mo Xian, Wei Huang. Biosynthesis and metabolic engineering of 1-hydroxyphenazine in Pseudomonas chlororaphis H18.
Microbial cell factories.
2021 Dec; 20(1):235. doi:
10.1186/s12934-021-01731-y
. [PMID: 34965873] - Jun Xiao, Aye Aye Thwe, Tingting Liu, Dafei Gong, Wanhua Lin, Changhua Shang, ZuJun Lu. Anti-Inflammatory Effects of an Extract from Pseudomonas aeruginosa and Its Purified Product 1-Hydroxyphenazine on RAW264.7 Cells.
Current microbiology.
2021 Jul; 78(7):2762-2773. doi:
10.1007/s00284-021-02544-3
. [PMID: 34043026] - T T Liu, F C Ye, C P Pang, T Q Yong, W D Tang, J Xiao, C H Shang, Z J Lu. Isolation and identification of bioactive substance 1-hydroxyphenazine from Pseudomonas aeruginosa and its antimicrobial activity.
Letters in applied microbiology.
2020 Sep; 71(3):303-310. doi:
10.1111/lam.13332
. [PMID: 32449160] - Valeri V Mossine, Deborah L Chance, James K Waters, Thomas P Mawhinney. Interaction of Bacterial Phenazines with Colistimethate in Bronchial Epithelial Cells.
Antimicrobial agents and chemotherapy.
2018 08; 62(8):. doi:
10.1128/aac.02349-17
. [PMID: 29784845] - Seema Dharni, Mansoor Alam, Komal Kalani, Abdul-Khaliq, Abdul Samad, Santosh Kumar Srivastava, Dharani Dhar Patra. Production, purification, and characterization of antifungal metabolite from Pseudomonas aeruginosa SD12, a new strain obtained from tannery waste polluted soil.
Journal of microbiology and biotechnology.
2012 May; 22(5):674-83. doi:
10.4014/jmb.1109.09061
. [PMID: 22561863] - Leland S Pierson, Elizabeth A Pierson. Metabolism and function of phenazines in bacteria: impacts on the behavior of bacteria in the environment and biotechnological processes.
Applied microbiology and biotechnology.
2010 May; 86(6):1659-70. doi:
10.1007/s00253-010-2509-3
. [PMID: 20352425] - D V Mavrodi, R F Bonsall, S M Delaney, M J Soule, G Phillips, L S Thomashow. Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1.
Journal of bacteriology.
2001 Nov; 183(21):6454-65. doi:
10.1128/jb.183.21.6454-6465.2001
. [PMID: 11591691] - G Ramafi, R Anderson, A Theron, C Feldman, G W Taylor, R Wilson, P J Cole. Exposure of N-formyl-L-methionyl-L-leucyl-L-phenylalanine-activated human neutrophils to the Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine is associated with impaired calcium efflux and potentiation of primary granule enzyme release.
Infection and immunity.
1999 Oct; 67(10):5157-62. doi:
10.1128/iai.67.10.5157-5162.1999
. [PMID: 10496890] - I Dormehl, G Ras, G Taylor, N Hugo. Effect of Pseudomonas aeruginosa-derived pyocyanin and 1-hydroxyphenazine on pulmonary mucociliary clearance monitored scintigraphically in the baboon model.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.
1991; 18(5):455-9. doi:
10.1016/0883-2897(91)90105-t
. [PMID: 1917514]