Dacarbazine (BioDeep_00000000370)

 

Secondary id: BioDeep_00001867494

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


Dacarbazine, Pharmaceutical Secondary Standard; Certified Reference Material

化学式: C6H10N6O (182.09160500000002)
中文名称: 达卡巴嗪
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 0.3%

分子结构信息

SMILES: CN(C)N/N=C\1/C(=NC=N1)C(=O)N
InChI: InChI=1S/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)

描述信息

Dacarbazine appears as white to ivory microcrystals or off-white crystalline solid. (NTP, 1992)
(E)-dacarbazine is a dacarbazine in which the N=N double bond adopts a trans-configuration.
An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Dacarbazine is an Alkylating Drug. The mechanism of action of dacarbazine is as an Alkylating Activity.
Dacarbazine (also known as DTIC) is an intravenously administered alkylating agent used in the therapy of Hodgkin disease and malignant melanoma. Dacarbazine therapy has been associated with serum enzyme elevations during therapy and occasional cases of severe and distinctive acute hepatic failure, probably caused by acute sinusoidal obstruction syndrome.
Dacarbazine is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04)
An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564)
Dacarbazine is only found in individuals that have used or taken this drug. It is an antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564)The mechanism of action is not known, but appears to exert cytotoxic effects via its action as an alkylating agent. Other theories include DNA synthesis inhibition by its action as a purine analog, and interaction with SH groups. Dacarbazine is not cell cycle-phase specific.
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
D009676 - Noxae > D000477 - Alkylating Agents
D000970 - Antineoplastic Agents

同义名列表

123 个代谢物同义名

Dacarbazine, Pharmaceutical Secondary Standard; Certified Reference Material; Imidazole-4(or 5)-carboxamide, 5(or 4)-(3,3-dimethyl-1-triazeno)-; Dacarbazine, United States Pharmacopeia (USP) Reference Standard; 4-(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide; 4-[(1E)-3,3-Dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide; (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide; (5E)-5-(dimethylaminohydrazinylidene)-4-imidazolecarboxamide; Dacarbazine, European Pharmacopoeia (EP) Reference Standard; 5-[(1E)-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide; 1 H-IMIDAZOLE-4-CARBOXAMIDE, 5-(3,3-DIMETHYL-1-TRIAZENYL)-; Dacarbazine, British Pharmacopoeia (BP) Reference Standard; 5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide; 1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-; 4-(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide; 4(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide; 4-[(E)-dimethylaminodiazenyl]-1H-imidazole-5-carboxamide; 5-(3,3-Dimethyltriaz-1-enyl)-1H-imidazole-4-carboxamide; 5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide; 5(or 4)-(dimethyltriazeno)imidazole-4(or 5)-carboxamide; 5-(3-3-dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide; 5-(dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide; (5Z)-5-(dimethylaminohydrazono)imidazole-4-carboxamide; (5E)-5-(dimethylaminohydrazono)imidazole-4-carboxamide; Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-; 5- (3,3-Dimethyl-1-triazenyl) imidazole-4-carboxamide; 4(5)-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide; IMIDAZOLE-4-CARBOXAMIDE, 5-(3,3-DIMETHYL-1-TRIAZENO1-; Imidazole-4(or 5)-carboxamide,3-dimethyl-1-triazeno)-; Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-; Carboxamide, 5-(3,3-dimethyl-1-triazeno)imidazole-4-; 5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide; 4-[(E)-dimethylaminoazo]-1H-imidazole-5-carboxamide; 1H-Imidazole-4-carboxamide,3-dimethyl-1-triazenyl)-; 4-(3,3-Dimethyl-1-triazeno)imidazole-5-carboxamide; 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide; 5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide; Imidazole-4-carboxamide,3-dimethyl-1-triazeno)-; Carboxamide,3-dimethyl-1-triazeno)imidazole-4-; 5-(Dimethyltriazeno)imidazole-4-carboxamide; 5-(Dimethyltriazeno)imidazole-4-carboximide; 4-(Dimethyltriazeno)imidazole-5-carboxamide; Dimethyl (triazeno) imidazolecarboxamide; Dimethyl-triazeno-imidazole-carboximide; Dimethyl Triazeno Imidazole Carboxamide; dimethyl-triazeno-imidazole carboxamide; Imidazole Carboxamide Dimethyltriazeno; (Dimethyltriazeno)imidazolecarboxamide; Dimethyl Triazeno Imidazol Carboxamide; Dimethyltriazenoimidazolecarboxamide; Dacarbazine [USAN:USP:INN:BAN:JAN]; Di-me-triazenoimidazolecarboxamide; Carboxamide, Dimethyl Imidazole; Imidazole Carboxamide, Dimethyl; Dimethyl Imidazole Carboxamide; DACARBAZINE [USP MONOGRAPH]; DACARBAZINUM [WHO-IP LATIN]; DACARBAZINE (USP MONOGRAPH); FDKXTQMXEQVLRF-ZHACJKMWSA-N; DACARBAZINE [EP MONOGRAPH]; DACARBAZINE (EP MONOGRAPH); DACARBAZINE [ORANGE BOOK]; Dacarbazine (JAN/USP/INN); Dacarbazino [INN-Spanish]; WLN: T5M CNJ DVZ ENUNN1&1; Dacarbazinum [INN-Latin]; Dacarbazine (DTIC-Dome); Imidazole carboxamide; DACARBAZINE [WHO-DD]; Dacarbazina Almirall; DACARBAZINE (USP-RS); DACARBAZINE [WHO-IP]; DACARBAZINE [USP-RS]; DACARBAZINE (MART.); DACARBAZINE [MART.]; DACARBAZINE [VANDF]; DACARBAZINE [USAN]; DACARBAZINE [IARC]; DACARBAZINE [HSDB]; dacarbazine - dtic; DACARBAZINE (IARC); DACARBAZINE [JAN]; DACARBAZINE [INN]; Dacarbazine-DTIC; DACARBAZINE [MI]; (E)-Dacarbazine; UNII-7GR28W0FJI; Tox21_111171_1; Biocarbazine R; Dtic-Dome (TN); Dacarbazinum; Tox21_111171; Biocarbazine; Tox21_201010; Dacarbazine; Dacarbasine; dacarbazina; Dacarbazino; Dicarbazine; Decarbazine; Dakarbazin; NCI-C04717; Dacarbazin; 7GR28W0FJI; NSC-45388; Fauldetic; AI3-52825; DTIC-Dome; Detimedac; DTIC Dome; dtic-aome; HSDB 3219; NSC 45388; Deticene; DTICDome; L01AX04; Asercit; Dacatic; ICDMT; DTIE; DTCI; DTIC; ICDT; DIC



数据库引用编号

24 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Herwig Strik, Thomas Efferth, Bernd Kaina. Artesunate in glioblastoma therapy: Case reports and review of clinical studies. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 123(?):155274. doi: 10.1016/j.phymed.2023.155274. [PMID: 38142662]
  • Nana Wang, Jiejun Wang, Pu Wang, Nan Ji, Shuhua Yue. Label-Free Raman Spectromicroscopy Unravels the Relationship between MGMT Methylation and Intracellular Lipid Accumulation in Glioblastoma. Analytical chemistry. 2023 08; 95(31):11567-11571. doi: 10.1021/acs.analchem.3c00967. [PMID: 37417930]
  • Junxia Pei, Zhou Su, Xin Zeng, Ya Zhong, Yamei Zhang, Yixi Yang, Qiuxia Lu, Jian Li, Yu Deng. Protocatechuic aldehyde acts synergistically with dacarbazine to augment DNA double-strand breaks and promote apoptosis in cutaneous melanoma cells. BMC complementary medicine and therapies. 2023 Apr; 23(1):111. doi: 10.1186/s12906-023-03933-w. [PMID: 37024907]
  • Sui Li, Xiaofang Xie, Fu Peng, Junrong Du, Cheng Peng. Regulation of temozolomide resistance via lncRNAs: Clinical and biological properties of lncRNAs in gliomas (Review). International journal of oncology. 2022 Sep; 61(3):. doi: 10.3892/ijo.2022.5391. [PMID: 35796022]
  • Yugo Horiuchi, Kenichi Hashimoto, Hideyuki Horikoshi, Azusa Sano, Yusuke Kawamura, Naoya Fujita, Motohiro Kimata, Yosuke Ono, Yasuhiro Obuchi, Arisa Makino, Mayuko Kaneko, Fumihiko Kimura, Kenji Itoh, Yuji Tanaka. Fulminant elderly adult-onset Still disease effectively treated with tocilizumab and methotrexate: A case report. Medicine. 2022 Jul; 101(28):e29354. doi: 10.1097/md.0000000000029354. [PMID: 35839054]
  • Valeria Internò, Roberta Rudà, Maria Chiara Sergi, Riccardo Soffietti, Camillo Porta. Newly diagnosed Glioblastoma Multiforme (GBM) during COVID-19 pandemic: changes in therapeutic approach to minimize in-hospital SARS-COV-2 contagion in pre-vaccine era. Acta bio-medica : Atenei Parmensis. 2022 Jul; 93(3):e2022067. doi: 10.23750/abm.v93i3.12452. [PMID: 35775774]
  • Federico Cucchiara, Giacomo Luci, Noemi Giannini, Filippo Sean Giorgi, Paola Orlandi, Marta Banchi, Antonello Di Paolo, Francesco Pasqualetti, Romano Danesi, Guido Bocci. Association of plasma levetiracetam concentration, MGMT methylation and sex with survival of chemoradiotherapy-treated glioblastoma patients. Pharmacological research. 2022 07; 181(?):106290. doi: 10.1016/j.phrs.2022.106290. [PMID: 35680010]
  • A D Makatsariya, E V Slukhanchuk, V O Bitsadze, J K H Khizroeva, M V Tretyakova, V I Tsibizova, I Elalamy, J-C Gris, E Grandone, N A Makatsariya, T Mashkova. Thrombotic microangiopathy, DIC-syndrome and COVID-19: link with pregnancy prothrombotic state. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2022 Jul; 35(13):2536-2544. doi: 10.1080/14767058.2020.1786811. [PMID: 32627622]
  • Eduardo Gutiérrez-Abejón, Francisco Herrera-Gómez, M Aránzazu Pedrosa-Naudín, Eduardo Tamayo, F Javier Álvarez. Hospitalized COVID-19 Patients with Severe Acute Respiratory Syndrome: A Population-Based Registry Analysis to Assess Clinical Findings, Pharmacological Treatment and Survival. Medicina (Kaunas, Lithuania). 2022 Jun; 58(6):. doi: 10.3390/medicina58060829. [PMID: 35744092]
  • Noha A El-Bassiouny, Maged W Helmy, Mostafa Alaa Eldin Hassan, Gehan A Khedr. The Cardioprotective Effect of Vitamin D in Breast Cancer Patients Receiving Adjuvant Doxorubicin Based Chemotherapy. Clinical breast cancer. 2022 06; 22(4):359-366. doi: 10.1016/j.clbc.2022.01.008. [PMID: 35241369]
  • Huijuan Wang, Chunfang Zhang, Chao Zhang, Yishan Wang, Kan Zhai, Zhaohui Tong. MicroRNA-122-5p regulates coagulation and inflammation through MASP1 and HO-1 genes. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2022 06; 100(?):105268. doi: 10.1016/j.meegid.2022.105268. [PMID: 35293311]
  • Paul B Googe, Stamatios Theocharis, Alexandros Pergaris, Haocheng Li, Yibing Yan, Edward F McKenna, Stergios J Moschos. Theragnostic significance of tumor-infiltrating lymphocytes and Ki67 in BRAFV600-mutant metastatic melanoma (BRIM-3 trial). Current problems in cancer. 2022 06; 46(3):100862. doi: 10.1016/j.currproblcancer.2022.100862. [PMID: 35398635]
  • Azra Kugić, Sanja Dabelić, Cvijeta Jakobušić Brala, Nina Dabelić, Monika Barbarić. Extra Virgin Olive Oil Secoiridoids Modulate the Metabolic Activity of Dacarbazine Pre-Treated and Treatment-Naive Melanoma Cells. Molecules (Basel, Switzerland). 2022 May; 27(10):. doi: 10.3390/molecules27103310. [PMID: 35630786]
  • Alessandro Malagoli, Luca Rossi, Alessia Zanni, Federico Muto, Alberto Tosetti, Stefano Tondi. Sustained right ventricular dysfunction in severe COVID-19: The role of disseminated intravascular coagulation. Echocardiography (Mount Kisco, N.Y.). 2022 04; 39(4):584-591. doi: 10.1111/echo.15332. [PMID: 35277886]
  • Elsa P Bianchini, Mahita Razanakolona, Julie Helms, Fouzia Zouiti, Amélie Couteau-Chardon, Viviana Marin-Esteban, Luc de Chaisemartin, Allan De-Carvalho, Roselyne Bironien, Sylvie Chollet-Martin, Cécile V Denis, Jean-Luc Diehl, Marc Vasse, Ferhat Meziani, Delphine Borgel. The Proteolytic Inactivation of Protein Z-Dependent Protease Inhibitor by Neutrophil Elastase Might Promote the Procoagulant Activity of Neutrophil Extracellular Traps in Sepsis. Thrombosis and haemostasis. 2022 04; 122(4):506-516. doi: 10.1055/a-1530-3980. [PMID: 34134169]
  • Larissa J Sanches, Poliana C Marinello, Walison A da Silva Brito, Natália M D Lopes, Rodrigo C Luiz, Rubens Cecchini, Alessandra L Cecchini. Metformin pretreatment reduces effect to dacarbazine and suppresses melanoma cell resistance. Cell biology international. 2022 Jan; 46(1):73-82. doi: 10.1002/cbin.11700. [PMID: 34506671]
  • Keisuke Mori, Yasuyuki Tsujita, Tetsunobu Yamane, Yutaka Eguchi. Decreasing Plasma Fibrinogen Levels in the Intensive Care Unit Are Associated with High Mortality Rates In Patients With Sepsis-Induced Coagulopathy. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 2022 Jan; 28(?):10760296221101386. doi: 10.1177/10760296221101386. [PMID: 35549920]
  • Hiroyuki Fujii, Taisuke Tsuji, Mio Sugitani, Yosuke Matsumoto, Tatsuya Yuba, Shunya Tanaka, Yoshifumi Suga, Aosa Matsuyama, Shiho Goda, Ayaka Omura, Shinsuke Shiotsu, Chieko Takumi, Seiko Ono, Noriya Hiraoka. Prolonged persistence of SARS-CoV-2 infection during A+AVD therapy for classical Hodgkin's lymphoma: A case report. Current problems in cancer. 2021 12; 45(6):100739. doi: 10.1016/j.currproblcancer.2021.100739. [PMID: 33810911]
  • Patrick M Honore, Sebastien Redant, Thierry Preseau, Keitiane Kaefer, Leonel Barreto Gutierrez, Rachid Attou, Andrea Gallerani, David De Bels. In Septic ICU Patients, Presepsin is Predictor of AKI, ARDS, and DIC: Beware of Some Potential Confounding Factors!. Shock (Augusta, Ga.). 2021 12; 56(6):1092. doi: 10.1097/shk.0000000000001802. [PMID: 33927138]
  • Yuichiro Shimoyama, Osamu Umegaki, Noriko Kadono, Toshiaki Minami. Response to A Letter to the Editor: In Septic ICU Patients, Presepsin is A Predictor of AKI, ARDS, and DIC-Renal Replacement Therapy Initiation only has A Minor Impact on The Results of The Present Study. Shock (Augusta, Ga.). 2021 12; 56(6):1092-1093. doi: 10.1097/shk.0000000000001801. [PMID: 33927139]
  • Hongxu Liu, William Kwame Amakye, Jiaoyan Ren. Codonopsis pilosula polysaccharide in synergy with dacarbazine inhibits mouse melanoma by repolarizing M2-like tumor-associated macrophages into M1-like tumor-associated macrophages. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Oct; 142(?):112016. doi: 10.1016/j.biopha.2021.112016. [PMID: 34385100]
  • Tejashree Waghule, Ranendra Narayan Saha, Gautam Singhvi. UV spectroscopic method for estimation of temozolomide: Application in stability studies in simulated plasma pH, degradation rate kinetics, formulation design, and selection of dissolution media. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Sep; 258(?):119848. doi: 10.1016/j.saa.2021.119848. [PMID: 33933945]
  • Mae Xintong Huo, Alzira Rocheteau M Avelino, Gurpreet Singh. Severe cutaneous presentation of hydralazine-induced ANCA vasculitis without renal or pulmonary involvement, complicated by DIC. BMJ case reports. 2021 May; 14(5):. doi: 10.1136/bcr-2020-238609. [PMID: 33975832]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Ying Liu, Li-Ying Sun, Zhi-Jun Zhu, Lin Wei, Wei Qu, Lin Wang, Lei-Lei Yuan, Zhi-Gui Zeng. Post-transplant lymphoproliferative disorder after paediatric liver transplantation. International journal of clinical practice. 2021 Apr; 75(4):e13843. doi: 10.1111/ijcp.13843. [PMID: 33222369]
  • Buket Kara, Kubilay K Kart, Yavuz Koksal. A Prolonged Activated Partial Thromboplastin Time in a Child With Hodgkin Lymphoma. Journal of pediatric hematology/oncology. 2021 04; 43(3):e401-e403. doi: 10.1097/mph.0000000000001732. [PMID: 32000198]
  • Akinleye Stephen Akinrinde, Halimot Olawalarami Hameed. Glycine and L-Arginine supplementation ameliorates gastro-duodenal toxicity in a rat model of NSAID (Diclofenac)-gastroenteropathy via inhibition of oxidative stress. Journal of basic and clinical physiology and pharmacology. 2021 Feb; 33(3):285-295. doi: 10.1515/jbcpp-2020-0307. [PMID: 33559459]
  • Yuhua Yue, Bingjun Zhou, Jiayuan Ai, Shun Feng. [Determination of dacarbazine in the urine of mice with melanoma by high performance liquid chromatography]. Se pu = Chinese journal of chromatography. 2020 Nov; 38(11):1302-1307. doi: 10.3724/sp.j.1123.2020.01003. [PMID: 34213101]
  • Yuichiro Shimoyama, Osamu Umegaki, Noriko Kadono, Toshiaki Minami. Urinary neutrophil gelatinase-associated lipocalin values alone and combined with Prognostic Index predict septic AKI, DIC, and shock: a pilot study. BMC research notes. 2020 Aug; 13(1):387. doi: 10.1186/s13104-020-05232-w. [PMID: 32811546]
  • Mina Alimohammadi, Monireh Golpur, Farshad Sohbatzadeh, Seyedehniaz Hadavi, Sander Bekeschus, Haleh Akhavan Niaki, Reza Valadan, Alireza Rafiei. Cold Atmospheric Plasma Is a Potent Tool to Improve Chemotherapy in Melanoma In Vitro and In Vivo. Biomolecules. 2020 07; 10(7):. doi: 10.3390/biom10071011. [PMID: 32650505]
  • Zhili Jin, Yini Wang, Na Wei, Zhao Wang. Hodgkin lymphoma-associated hemophagocytic lymphohistiocytosis-a dangerous disease. Annals of hematology. 2020 Jul; 99(7):1575-1581. doi: 10.1007/s00277-020-04093-4. [PMID: 32500223]
  • Rainer Seitz, Wolfgang Schramm. DIC in COVID-19: Implications for prognosis and treatment?. Journal of thrombosis and haemostasis : JTH. 2020 07; 18(7):1798-1799. doi: 10.1111/jth.14878. [PMID: 32344469]
  • Brendan O'Kelly, Padraig McGettrick, Daniel Angelov, Michael Fay, Tara McGinty, Aoife G Cotter, Gerard Sheehan, John S Lambert. Outcome of a patient with refractory Hodgkin lymphoma on pembrolizumab, infected with SARS-CoV-2. British journal of haematology. 2020 Jul; 190(1):e1-e3. doi: 10.1111/bjh.16798. [PMID: 32379903]
  • Nerea Arratibel, Eduardo Sobejano, Jose Carlos Moran, Luis G Diaz, Almudena Blázquez, Mónica Baile, Álvaro Veiga, Maria Dolores Caballero, Ramón García-Sanz. A Case of Paraneoplastic Cerebellar Degeneration that Preceded the Diagnosis of Classical Hodgkin's Lymphoma by 16 Months. The American journal of case reports. 2020 Jun; 21(?):e922342. doi: 10.12659/ajcr.922342. [PMID: 32574156]
  • Y D Wang, S P Zhang, Q Z Wei, M M Zhao, H Mei, Z L Zhang, Y Hu. [COVID-19 complicated with DIC: 2 cases report and literatures review]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 2020 03; 41(3):245-247. doi: 10.3760/cma.j.issn.0253-2727.2020.0001. [PMID: 32133824]
  • Yeliz Demir, Cüneyt Türkeş, Şükrü Beydemir. Molecular Docking Studies and Inhibition Properties of Some Antineoplastic Agents against Paraoxonase-I. Anti-cancer agents in medicinal chemistry. 2020; 20(7):887-896. doi: 10.2174/1871520620666200218110645. [PMID: 32067621]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Masanobu Tsubaki, Tomoya Takeda, Naoya Obata, Keishi Kawashima, Mitsuki Tabata, Motohiro Imano, Takao Satou, Shozo Nishida. Combination therapy with dacarbazine and statins improved the survival rate in mice with metastatic melanoma. Journal of cellular physiology. 2019 08; 234(10):17975-17989. doi: 10.1002/jcp.28430. [PMID: 30834527]
  • Yuki Yokota, Kazutaka Mitsuke, Hiroko Minami, Akihiko Morita, Hiromichi Takahashi, Satoshi Kamei. [Acute sensory neuropathy associated with Hodgkin's lymphoma: a case study]. Rinsho shinkeigaku = Clinical neurology. 2019 Jun; 59(6):349-355. doi: 10.5692/clinicalneurol.cn-001271. [PMID: 31142709]
  • Raimundo Gonçalves de Oliveira Júnior, Antoine Bonnet, Estelle Braconnier, Hugo Groult, Grégoire Prunier, Laureen Beaugeard, Raphäel Grougnet, Jackson Roberto Guedes da Silva Almeida, Christiane Adrielly Alves Ferraz, Laurent Picot. Bixin, an apocarotenoid isolated from Bixa orellana L., sensitizes human melanoma cells to dacarbazine-induced apoptosis through ROS-mediated cytotoxicity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2019 Mar; 125(?):549-561. doi: 10.1016/j.fct.2019.02.013. [PMID: 30738990]
  • Maria João Ramalho, Stéphanie Andrade, Manuel Álvaro Neto Coelho, Joana Angélica Loureiro, Maria Carmo Pereira. Biophysical interaction of temozolomide and its active metabolite with biomembrane models: The relevance of drug-membrane interaction for Glioblastoma Multiforme therapy. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2019 Mar; 136(?):156-163. doi: 10.1016/j.ejpb.2019.01.015. [PMID: 30682492]
  • Indranil Banerjee, Manjarika De, Goutam Dey, Rashmi Bharti, Sankha Chattopadhyay, Nahid Ali, Partha Chakrabarti, Rui L Reis, Subhas C Kundu, Mahitosh Mandal. A peptide-modified solid lipid nanoparticle formulation of paclitaxel modulates immunity and outperforms dacarbazine in a murine melanoma model. Biomaterials science. 2019 Feb; 7(3):1161-1178. doi: 10.1039/c8bm01403e. [PMID: 30652182]
  • Parul Thakral, Ishita Sen, Vineet Pant, Santosh Kumar Gupta, Sugandha Dureja, Jyotsna Kumari, Sunil Kumar, Pallavi Un, Vindhya Malasani. Dosimetric analysis of patients with gastro entero pancreatic neuroendocrine tumors (NETs) treated with PRCRT (peptide receptor chemo radionuclide therapy) using Lu-177 DOTATATE and capecitabine/temozolomide (CAP/TEM). The British journal of radiology. 2018 Nov; 91(1091):20170172. doi: 10.1259/bjr.20170172. [PMID: 30028180]
  • Anam Khan, Mohd Aqil, Syed Sarim Imam, Abdul Ahad, Yasmin Sultana, Asgar Ali, Khalid Khan. Temozolomide loaded nano lipid based chitosan hydrogel for nose to brain delivery: Characterization, nasal absorption, histopathology and cell line study. International journal of biological macromolecules. 2018 Sep; 116(?):1260-1267. doi: 10.1016/j.ijbiomac.2018.05.079. [PMID: 29775717]
  • Vivian Adamski, Christina Schmitt, Florian Ceynowa, Rainer Adelung, Ralph Lucius, Michael Synowitz, Kirsten Hattermann, Janka Held-Feindt. Effects of sequentially applied single and combined temozolomide, hydroxychloroquine and AT101 treatment in a long-term stimulation glioblastoma in vitro model. Journal of cancer research and clinical oncology. 2018 Aug; 144(8):1475-1485. doi: 10.1007/s00432-018-2680-y. [PMID: 29858681]
  • Hong Li, Junjie Chen, Xiao Wang, Mei He, Zhenyu Zhang, Ying Cen. Nodal induced by hypoxia exposure contributes to dacarbazine resistance and the maintenance of stemness in melanoma cancer stem‑like cells. Oncology reports. 2018 Jun; 39(6):2855-2864. doi: 10.3892/or.2018.6387. [PMID: 29693169]
  • Amy L Winship, Monika Bakai, Urooza Sarma, Seng H Liew, Karla J Hutt. Dacarbazine depletes the ovarian reserve in mice and depletion is enhanced with age. Scientific reports. 2018 04; 8(1):6516. doi: 10.1038/s41598-018-24960-5. [PMID: 29695822]
  • Maria Angeles Marques-Torrejon, Ester Gangoso, Steven M Pollard. Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture. Disease models & mechanisms. 2018 02; 11(2):. doi: 10.1242/dmm.031435. [PMID: 29196443]
  • Meiguang Zheng, Shengwen Wang, Zhenghao Liu, Lin Xie, Yuefei Deng. Development of temozolomide coated nano zinc oxide for reversing the resistance of malignant glioma stem cells. Materials science & engineering. C, Materials for biological applications. 2018 Feb; 83(?):44-50. doi: 10.1016/j.msec.2017.07.015. [PMID: 29208287]
  • Nausicaa Clemente, Benedetta Ferrara, Casimiro Luca Gigliotti, Elena Boggio, Maria Teresa Capucchio, Elena Biasibetti, Davide Schiffer, Marta Mellai, Laura Annovazzi, Luigi Cangemi, Elisabetta Muntoni, Gianluca Miglio, Umberto Dianzani, Luigi Battaglia, Chiara Dianzani. Solid Lipid Nanoparticles Carrying Temozolomide for Melanoma Treatment. Preliminary In Vitro and In Vivo Studies. International journal of molecular sciences. 2018 Jan; 19(2):. doi: 10.3390/ijms19020255. [PMID: 29364157]
  • Sadhana Jackson, Jon Weingart, Edjah K Nduom, Thura T Harfi, Richard T George, Dorothea McAreavey, Xiaobu Ye, Nicole M Anders, Cody Peer, William D Figg, Mark Gilbert, Michelle A Rudek, Stuart A Grossman. The effect of an adenosine A2A agonist on intra-tumoral concentrations of temozolomide in patients with recurrent glioblastoma. Fluids and barriers of the CNS. 2018 Jan; 15(1):2. doi: 10.1186/s12987-017-0088-8. [PMID: 29332604]
  • Yutaro Yamamoto, Arata Tomiyama, Nobuyoshi Sasaki, Hideki Yamaguchi, Takuya Shirakihara, Katsuhiko Nakashima, Kosuke Kumagai, Satoru Takeuchi, Terushige Toyooka, Naoki Otani, Kojiro Wada, Yoshitaka Narita, Koichi Ichimura, Ryuichi Sakai, Hiroki Namba, Kentaro Mori. Intracellular cholesterol level regulates sensitivity of glioblastoma cells against temozolomide-induced cell death by modulation of caspase-8 activation via death receptor 5-accumulation and activation in the plasma membrane lipid raft. Biochemical and biophysical research communications. 2018 01; 495(1):1292-1299. doi: 10.1016/j.bbrc.2017.11.113. [PMID: 29162448]
  • Lingzhi Wang, Yuexia Peng, Jianxin Peng, Min Shao, Li Ma, Zhuoli Zhu, Guocheng Zhong, Zhengyuan Xia, Huansen Huang. Tramadol attenuates the sensitivity of glioblastoma to temozolomide through the suppression of Cx43‑mediated gap junction intercellular communication. International journal of oncology. 2018 Jan; 52(1):295-304. doi: 10.3892/ijo.2017.4188. [PMID: 29115581]
  • Jicai Zhang, Xiang Xiao, Jianming Zhu, Ziyun Gao, Xianliang Lai, Xingen Zhu, Guohua Mao. Lactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy. International journal of nanomedicine. 2018; 13(?):3039-3051. doi: 10.2147/ijn.s161163. [PMID: 29861635]
  • Guo-Zhong Yi, Wei Xiang, Wen-Yan Feng, Zi-Yang Chen, Yao-Min Li, Sheng-Ze Deng, Man-Lan Guo, Liang Zhao, Xue-Gang Sun, Min-Yi He, Song-Tao Qi, Ya-Wei Liu. Identification of Key Candidate Proteins and Pathways Associated with Temozolomide Resistance in Glioblastoma Based on Subcellular Proteomics and Bioinformatical Analysis. BioMed research international. 2018; 2018(?):5238760. doi: 10.1155/2018/5238760. [PMID: 29687002]
  • Yushi Yamauchi, Yoshihisa Matsukawa, Masashi Kato, Yasushi Yoshino, Tokunori Yamamoto, Hiroaki Kobayashi, Momokazu Gotoh. [A CASE OF MALIGNANT PARAGANGLIOMA OF THE URINARY BLADDER TREATED WITH CYCLOPHOSPHAMIDE, VINCRISTINE, AND DACARBAZINE CHEMOTHERAPY AND METAIODOBENZYLGUANIDINE THERAPY]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology. 2018; 109(2):106-110. doi: 10.5980/jpnjurol.109.106. [PMID: 31006739]
  • Mariko Kinoshita, Ai Yamada, Daisuke Sawa, Sachiyo Kamimura, Mitsuru Miyachi, Hiroshi Moritake. Successful treatment of metastatic alveolar rhabdomyosarcoma with MGMT gene promoter methylation by temozolomide-based combination chemotherapy. Pediatric blood & cancer. 2018 Jan; 65(1):. doi: 10.1002/pbc.26750. [PMID: 28834127]
  • Nu-Man Tsai, Kai-Fu Chang, Jun-Cheng Wang. Juniperus Communis Extract Exerts Antitumor Effects in Human Glioblastomas Through Blood-Brain Barrier. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2018; 49(6):2443-2462. doi: 10.1159/000493842. [PMID: 30261501]
  • J G Nam, K M Kang, S H Choi, W H Lim, R-E Yoo, J-H Kim, T J Yun, C-H Sohn. Comparison between the Prebolus T1 Measurement and the Fixed T1 Value in Dynamic Contrast-Enhanced MR Imaging for the Differentiation of True Progression from Pseudoprogression in Glioblastoma Treated with Concurrent Radiation Therapy and Temozolomide Chemotherapy. AJNR. American journal of neuroradiology. 2017 Dec; 38(12):2243-2250. doi: 10.3174/ajnr.a5417. [PMID: 29074633]
  • Sani H Kizilbash, Shiv K Gupta, Kenneth Chang, Ryo Kawashima, Karen E Parrish, Brett L Carlson, Katrina K Bakken, Ann C Mladek, Mark A Schroeder, Paul A Decker, Gaspar J Kitange, Yuqiao Shen, Ying Feng, Andrew A Protter, William F Elmquist, Jann N Sarkaria. Restricted Delivery of Talazoparib Across the Blood-Brain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma. Molecular cancer therapeutics. 2017 Dec; 16(12):2735-2746. doi: 10.1158/1535-7163.mct-17-0365. [PMID: 28947502]
  • Varun Kumar, Daniel Radin, Donna Leonardi. Probing the Oncolytic and Chemosensitizing Effects of Dihydrotanshinone in an In Vitro Glioblastoma Model. Anticancer research. 2017 11; 37(11):6025-6030. doi: 10.21873/anticanres.12049. [PMID: 29061781]
  • A Guidetti, A Mazzocchi, R Miceli, E Paterno', F Taverna, F Spina, F Crippa, L Farina, P Corradini, A M Gianni, S Viviani. Early reduction of serum TARC levels may predict for success of ABVD as frontline treatment in patients with Hodgkin Lymphoma. Leukemia research. 2017 11; 62(?):91-97. doi: 10.1016/j.leukres.2017.09.018. [PMID: 28992524]
  • Sara M Federico, M Beth McCarville, Barry L Shulkin, Paul M Sondel, Jacquelyn A Hank, Paul Hutson, Michael Meagher, Aaron Shafer, Catherine Y Ng, Wing Leung, William E Janssen, Jianrong Wu, Shenghua Mao, Rachel C Brennan, Victor M Santana, Alberto S Pappo, Wayne L Furman. A Pilot Trial of Humanized Anti-GD2 Monoclonal Antibody (hu14.18K322A) with Chemotherapy and Natural Killer Cells in Children with Recurrent/Refractory Neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Nov; 23(21):6441-6449. doi: 10.1158/1078-0432.ccr-17-0379. [PMID: 28939747]
  • Alessandro Canella, Alessandra M Welker, Ji Young Yoo, Jihong Xu, Fazly S Abas, Divya Kesanakurti, Prabakaran Nagarajan, Christine E Beattie, Erik P Sulman, Joseph Liu, Joy Gumin, Frederick F Lang, Metin N Gurcan, Balveen Kaur, Deepa Sampath, Vinay K Puduvalli. Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Oct; 23(20):6215-6226. doi: 10.1158/1078-0432.ccr-16-3151. [PMID: 28679777]
  • Ezequiel Cordova, Laura Morganti, Andrea Odzak, Florencia Arcondo, Mariana Silva, Marcelo Zylberman, Claudia Rodriguez. Severe hypokalemia due to a possible drug-drug interaction between vinblastine and antiretrovirals in a HIV-infected patient with Hodgkin's lymphoma. International journal of STD & AIDS. 2017 10; 28(12):1259-1262. doi: 10.1177/0956462417703026. [PMID: 28403692]
  • Rebecca Y Tay, Elizabeth Blackley, Catriona McLean, Maggie Moore, Peter Bergin, Sanjeev Gill, Andrew Haydon. Successful use of equine anti-thymocyte globulin (ATGAM) for fulminant myocarditis secondary to nivolumab therapy. British journal of cancer. 2017 Sep; 117(7):921-924. doi: 10.1038/bjc.2017.253. [PMID: 28797029]
  • Qian Tan, Xiaoqiong Yan, Lin Song, Hongxiang Yi, Ping Li, Guobin Sun, Danfang Yu, Le Li, Zheng Zeng, Zhenlin Guo. Induction of Mitochondrial Dysfunction and Oxidative Damage by Antibiotic Drug Doxycycline Enhances the Responsiveness of Glioblastoma to Chemotherapy. Medical science monitor : international medical journal of experimental and clinical research. 2017 Aug; 23(?):4117-4125. doi: 10.12659/msm.903245. [PMID: 28842551]
  • Quintino Giorgio D'Alessandris, Mauro Biffoni, Maurizio Martini, Daniele Runci, Mariachiara Buccarelli, Tonia Cenci, Michele Signore, Louis Stancato, Alessandro Olivi, Ruggero De Maria, Luigi M Larocca, Lucia Ricci-Vitiani, Roberto Pallini. The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response. Neuro-oncology. 2017 Aug; 19(8):1097-1108. doi: 10.1093/neuonc/now304. [PMID: 28204560]
  • Gulcin Tezcan, Berrin Tunca, Hilal Demirci, Ahmet Bekar, Mevlut Ozgur Taskapilioglu, Hasan Kocaeli, Unal Egeli, Gulsah Cecener, Sahsine Tolunay, Ozgur Vatan. Olea europaea Leaf Extract Improves the Efficacy of Temozolomide Therapy by Inducing MGMT Methylation and Reducing P53 Expression in Glioblastoma. Nutrition and cancer. 2017 Aug; 69(6):873-880. doi: 10.1080/01635581.2017.1339810. [PMID: 28718668]
  • Monika Witusik-Perkowska, Magdalena Zakrzewska, Beata Sikorska, Wielislaw Papierz, Dariusz J Jaskolski, Janusz Szemraj, Pawel P Liberski. Glioblastoma-derived cells in vitro unveil the spectrum of drug resistance capability - comparative study of tumour chemosensitivity in different culture systems. Bioscience reports. 2017 Jun; 37(3):. doi: 10.1042/bsr20170058. [PMID: 28522553]
  • Bhim Bali Prasad, Purnendu Kumar Pathak. Development of surface imprinted nanospheres using the inverse suspension polymerization method for electrochemical ultra sensing of dacarbazine. Analytica chimica acta. 2017 Jun; 974(?):75-86. doi: 10.1016/j.aca.2017.04.001. [PMID: 28535884]
  • Liliana R Oancea-Castillo, Carmen Klein, Amir Abdollahi, Klaus-Josef Weber, Anne Régnier-Vigouroux, Ivana Dokic. Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines. Cancer biology & therapy. 2017 06; 18(6):400-406. doi: 10.1080/15384047.2017.1323583. [PMID: 28494176]
  • Matthias Holdhoff, Xiaobu Ye, Jeffrey G Supko, Louis B Nabors, Arati S Desai, Tobias Walbert, Glenn J Lesser, William L Read, Frank S Lieberman, Martin A Lodge, Jeffrey Leal, Joy D Fisher, Serena Desideri, Stuart A Grossman, Richard L Wahl, David Schiff. Timed sequential therapy of the selective T-type calcium channel blocker mibefradil and temozolomide in patients with recurrent high-grade gliomas. Neuro-oncology. 2017 06; 19(6):845-852. doi: 10.1093/neuonc/nox020. [PMID: 28371832]
  • S Denies, L Cicchelero, H de Rooster, S Daminet, I Polis, I Van de Maele, N N Sanders. Immunological and angiogenic markers during metronomic temozolomide and cyclophosphamide in canine cancer patients. Veterinary and comparative oncology. 2017 Jun; 15(2):594-605. doi: 10.1111/vco.12203. [PMID: 26961119]
  • Dongyong Zhang, Bo Qiu, Yunjie Wang, Yanlei Guan, Luyang Zhang, Anhua Wu. Temozolomide increases MHC-I expression via NF-κB signaling in glioma stem cells. Cell biology international. 2017 Jun; 41(6):680-690. doi: 10.1002/cbin.10773. [PMID: 28403532]
  • Hai Lu, Ruya Sheng, Chunhong Zhang, Ta-Ya Lee. Comments regarding 'Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature'. Archives of toxicology. 2017 06; 91(6):2493-2494. doi: 10.1007/s00204-016-1915-4. [PMID: 28032144]
  • Nan Wang, Pei Sun, Mingming Lv, Gangsheng Tong, Xin Jin, Xinyuan Zhu. Mustard-inspired delivery shuttle for enhanced blood-brain barrier penetration and effective drug delivery in glioma therapy. Biomaterials science. 2017 May; 5(5):1041-1050. doi: 10.1039/c7bm00133a. [PMID: 28378865]
  • Zong-Yang Li, Ce Zhang, Lei Chen, Bao-Dong Chen, Qing-Zhong Li, Xie-Jun Zhang, Wei-Ping Li. Radicol, a Novel Trinorguaiane-Type Sesquiterpene, Induces Temozolomide-Resistant Glioma Cell Apoptosis via ER Stress and Akt/mTOR Pathway Blockade. Phytotherapy research : PTR. 2017 May; 31(5):729-739. doi: 10.1002/ptr.5793. [PMID: 28240396]
  • James C League-Pascual, Cynthia M Lester-McCully, Shaefali Shandilya, Lukas Ronner, Louis Rodgers, Rafael Cruz, Cody J Peer, William D Figg, Katherine E Warren. Plasma and cerebrospinal fluid pharmacokinetics of select chemotherapeutic agents following intranasal delivery in a non-human primate model. Journal of neuro-oncology. 2017 05; 132(3):401-407. doi: 10.1007/s11060-017-2388-x. [PMID: 28290002]
  • S Stacchiotti, M Saponara, R Frapolli, M Tortoreto, D Cominetti, S Provenzano, T Negri, G P Dagrada, A Gronchi, C Colombo, B Vincenzi, G Badalamenti, V Zuco, S L Renne, P Collini, C Morosi, A P Dei Tos, E Bello, S Pilotti, P G Casali, M D'Incalci, N Zaffaroni. Patient-derived solitary fibrous tumour xenografts predict high sensitivity to doxorubicin/dacarbazine combination confirmed in the clinic and highlight the potential effectiveness of trabectedin or eribulin against this tumour. European journal of cancer (Oxford, England : 1990). 2017 05; 76(?):84-92. doi: 10.1016/j.ejca.2017.02.002. [PMID: 28284173]
  • Wei Chen, Xin-Ke Xu, Jun-Liang Li, Kuan-Kei Kong, Hui Li, Cheng Chen, Jing He, Fangyu Wang, Ping Li, Xiao-Song Ge, Fang-Cheng Li. MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression. Oncotarget. 2017 Apr; 8(14):22783-22799. doi: 10.18632/oncotarget.15199. [PMID: 28187000]
  • Sarah J Nelson, Achuta K Kadambi, Ilwoo Park, Yan Li, Jason Crane, Marram Olson, Annette Molinaro, Ritu Roy, Nicholas Butowski, Soonmee Cha, Susan Chang. Association of early changes in 1H MRSI parameters with survival for patients with newly diagnosed glioblastoma receiving a multimodality treatment regimen. Neuro-oncology. 2017 03; 19(3):430-439. doi: 10.1093/neuonc/now159. [PMID: 27576874]
  • Alissa A Thomas, Jan L Fisher, Thomas H Hampton, Brock C Christensen, Gregory J Tsongalis, Gilbert J Rahme, Chery A Whipple, Sandra E Steel, Melissa C Davis, Arti B Gaur, Lionel D Lewis, Marc S Ernstoff, Camilo E Fadul. Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma. Cancer immunology, immunotherapy : CII. 2017 Mar; 66(3):379-389. doi: 10.1007/s00262-016-1941-3. [PMID: 27942839]
  • Quan Cheng, Xiaoqiang Ma, Hui Cao, Zigui Chen, Xin Wan, Rui Chen, Renjun Peng, Jun Huang, Bing Jiang. Role of miR-223/paired box 6 signaling in temozolomide chemoresistance in glioblastoma multiforme cells. Molecular medicine reports. 2017 Feb; 15(2):597-604. doi: 10.3892/mmr.2016.6078. [PMID: 28035389]
  • Kishore Balasubramanian, Michael Evangelopoulos, Brandon S Brown, Alessandro Parodi, Christian Celia, Iman K Yazdi, Ennio Tasciotti. Ghee Butter as a Therapeutic Delivery System. Journal of nanoscience and nanotechnology. 2017 Feb; 17(2):977-82. doi: 10.1166/jnn.2017.12623. [PMID: 29671486]
  • Zachary R Stephen, Rachel N Gebhart, Mike Jeon, Allison A Blair, Richard G Ellenbogen, John R Silber, Miqin Zhang. pH-Sensitive O6-Benzylguanosine Polymer Modified Magnetic Nanoparticles for Treatment of Glioblastomas. Bioconjugate chemistry. 2017 01; 28(1):194-202. doi: 10.1021/acs.bioconjchem.6b00545. [PMID: 27936607]
  • Jin-Xue He, Meng Wang, Xia-Juan Huan, Chuan-Huizi Chen, Shan-Shan Song, Ying-Qing Wang, Xue-Mei Liao, Cun Tan, Qian He, Lin-Jiang Tong, Yu-Ting Wang, Xiao-Hua Li, Yi Su, Yan-Yan Shen, Yi-Ming Sun, Xin-Ying Yang, Yi Chen, Zhi-Wei Gao, Xiao-Yan Chen, Bing Xiong, Xiu-Lian Lu, Jian Ding, Chun-Hao Yang, Ze-Hong Miao. Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution. Oncotarget. 2017 Jan; 8(3):4156-4168. doi: 10.18632/oncotarget.13749. [PMID: 27926532]
  • Mark R Gilbert, Stephanie L Pugh, Ken Aldape, A Gregory Sorensen, Tom Mikkelsen, Marta Penas-Prado, Felix Bokstein, Young Kwok, R Jeffrey Lee, Minesh Mehta. NRG oncology RTOG 0625: a randomized phase II trial of bevacizumab with either irinotecan or dose-dense temozolomide in recurrent glioblastoma. Journal of neuro-oncology. 2017 01; 131(1):193-199. doi: 10.1007/s11060-016-2288-5. [PMID: 27770279]
  • Mihaela Surcel, Carolina Constantin, Constantin Caruntu, Sabina Zurac, Monica Neagu. Inflammatory Cytokine Pattern Is Sex-Dependent in Mouse Cutaneous Melanoma Experimental Model. Journal of immunology research. 2017; 2017(?):9212134. doi: 10.1155/2017/9212134. [PMID: 29318162]
  • Anam Khan, Syed Sarim Imam, Mohammed Aqil, Abdul Ahad, Yasmin Sultana, Asgar Ali, Khalid Khan. Brain Targeting of Temozolomide via the Intranasal Route Using Lipid-Based Nanoparticles: Brain Pharmacokinetic and Scintigraphic Analyses. Molecular pharmaceutics. 2016 11; 13(11):3773-3782. doi: 10.1021/acs.molpharmaceut.6b00586. [PMID: 27661966]
  • Jie Qu, Liangqiao Zhang, Zhihua Chen, Guohua Mao, Ziyun Gao, Xianliang Lai, Xingen Zhu, Jianming Zhu. Nanostructured lipid carriers, solid lipid nanoparticles, and polymeric nanoparticles: which kind of drug delivery system is better for glioblastoma chemotherapy?. Drug delivery. 2016 Nov; 23(9):3408-3416. doi: 10.1080/10717544.2016.1189465. [PMID: 27181462]
  • Muhammad Zubair Malik, Mahmood Ahmad, Saleh Muahammad, Muhammad Naeem Aamir. Pharmacokinetic evaluation of anticancer drugs in Hodgkin's lymphoma patients after their simultaneous administration. Pakistan journal of pharmaceutical sciences. 2016 Nov; 29(6):2079-2082. doi: NULL. [PMID: 28375127]
  • Roopa Rai, Monali Banerjee, Darren H Wong, Emma McCullagh, Ashu Gupta, Shailendra Tripathi, Eduardo Riquelme, Ramnivas Jangir, Shyamraj Yadav, Mohd Raja, Pankaj Melkani, Vikas Dixit, Umesh Patil, Ritesh Shrivastava, Sandip Middya, Felipe Olivares, Javier Guerrero, Arjun Surya, Son M Pham, Sebastián Bernales, Andrew A Protter, David T Hung, Sarvajit Chakravarty. Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide. Bioorganic & medicinal chemistry letters. 2016 10; 26(20):5103-5109. doi: 10.1016/j.bmcl.2016.08.064. [PMID: 27614414]
  • Miaojing Wu, Yanghua Fan, Shigang Lv, Bing Xiao, Minhua Ye, Xingen Zhu. Vincristine and temozolomide combined chemotherapy for the treatment of glioma: a comparison of solid lipid nanoparticles and nanostructured lipid carriers for dual drugs delivery. Drug delivery. 2016 Oct; 23(8):2720-2725. doi: 10.3109/10717544.2015.1058434. [PMID: 26203691]
  • Sarah J Nelson, Yan Li, Janine M Lupo, Marram Olson, Jason C Crane, Annette Molinaro, Ritu Roy, Jennifer Clarke, Nicholas Butowski, Michael Prados, Soonmee Cha, Susan M Chang. Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab. Journal of neuro-oncology. 2016 10; 130(1):171-179. doi: 10.1007/s11060-016-2229-3. [PMID: 27535746]
  • F K Holla, T J Postma, M A Blankenstein, T J M van Mierlo, M J Vos, E M Sizoo, M de Groot, B M J Uitdehaag, J Buter, M Klein, J C Reijneveld, J J Heimans. Prognostic value of the S100B protein in newly diagnosed and recurrent glioma patients: a serial analysis. Journal of neuro-oncology. 2016 09; 129(3):525-532. doi: 10.1007/s11060-016-2204-z. [PMID: 27401156]
  • Jeffrey J Raizer, James P Chandler, Roberto Ferrarese, Sean A Grimm, Robert M Levy, Kenji Muro, Joshua Rosenow, Irene Helenowski, Alfred Rademaker, Martin Paton, Markus Bredel. A phase II trial evaluating the effects and intra-tumoral penetration of bortezomib in patients with recurrent malignant gliomas. Journal of neuro-oncology. 2016 08; 129(1):139-46. doi: 10.1007/s11060-016-2156-3. [PMID: 27300524]
  • Hai Wang, Wenfeng Feng, Yuntao Lu, Hezhen Li, Wei Xiang, Ziyang Chen, Minyi He, Liang Zhao, Xuegang Sun, Bingxi Lei, Songtao Qi, Yawei Liu. Expression of dynein, cytoplasmic 2, heavy chain 1 (DHC2) associated with glioblastoma cell resistance to temozolomide. Scientific reports. 2016 07; 6(?):28948. doi: 10.1038/srep28948. [PMID: 27375225]
  • Roman Akasov, Daria Zaytseva-Zotova, Sergey Burov, Maria Leko, Monique Dontenwill, Manuela Chiper, Thierry Vandamme, Elena Markvicheva. Formation of multicellular tumor spheroids induced by cyclic RGD-peptides and use for anticancer drug testing in vitro. International journal of pharmaceutics. 2016 Jun; 506(1-2):148-57. doi: 10.1016/j.ijpharm.2016.04.005. [PMID: 27107900]