Cytidine (BioDeep_00000000364)

 

Secondary id: BioDeep_00000398587

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

化学式: C9H13N3O5 (243.0855)
中文名称: 胞嘧啶核苷, 胞苷
谱图信息: 最多检出来源 Homo sapiens(plant) 10.57%

Reviewed

Last reviewed on 2024-07-01.

Cite this Page

Cytidine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/cytidine (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000364). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O
InChI: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1

描述信息

Cytidine is a nucleoside that is composed of the base cytosine linked to the five-carbon sugar D-ribose. Cytidine is a pyrimidine that besides being incorporated into nucleic acids, can serve as a substrate for the salvage pathway of pyrimidine nucleotide synthesis. It is a precursor of cytidine triphosphate (CTP) needed in the phosphatidylcholine (PC) and phosphatidylethanolamine (PE) biosynthetic pathways. These variations probably reflect the species differences in cytidine deaminase, the enzyme that converts cytidine to uridine in the body. The transport of cytidine into the brains extracellular fluid, and then into neurons and glia, are essential prerequisites for cytidine to be utilized in the brain. An efficient mechanism mediating the brain uptake of circulating cytidine has not yet been demonstrated. The biosynthesis of PC, the most abundant phosphatide in the brain, via the Kennedy pathway requires phosphocholine and cytidine triphosphate (CTP), a cytidine nucleotide involved in the rate-limiting step. The enzyme that converts CTP to endogenous CDP-choline (CTP:phosphocholine cytidylyltransferase) is unsaturated at physiological brain CTP levels. APOBEC is a family of enzymes that has been discovered with the ability to deaminate cytidines on RNA or DNA. The human apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G protein (APOBEC3G, or hA3G), provides cells with an intracellular antiretroviral activity that is associated with the hypermutation of viral DNA through cytidine deamination. Indeed, hA3G belongs to a family of vertebrate proteins that contains one or two copies of a signature sequence motif unique to cytidine deaminases (CTDAs) (PMID: 16769123, 15780864, 16720547).
Cytidine is a nucleoside that is composed of the base cytosine linked to the five-carbon sugar D-ribose. Cytidine is a pyrimidine that besides being incorporated into nucleic acids, can serve as substrate for the salvage pathway of pyrimidine nucleotide synthesis; as precursor of the cytidine triphosphate (CTP) needed in the phosphatidylcholine (PC) and phosphatidylethanolamine (PE) biosynthetic pathway. These variations probably reflect the species differences in cytidine deaminase, the enzyme that converts cytidine to uridine in the body. The transports of cytidine into the brains extracellular fluid, and then into neurons and glia, are essential prerequisites for cytidine to be utilized in brain. An efficient mechanism mediating the brain uptake of circulating cytidine has not yet been demonstrated. The biosynthesis of PC, the most abundant phosphatide in the brain, via the Kennedy pathway requires phosphocholine and cytidine triphosphate (CTP), a cytidine nucleotide, which is involved in the rate-limiting step. The enzyme that converts CTP to endogenous CDP-choline (CTP: phosphocholine cytidylyltransferase) is unsaturated at physiological brain CTP levels.
Cytidine is a white crystalline powder. (NTP, 1992)
Cytidine is a pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a cytosine.
Cytidine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Cytidine is a natural product found in Fritillaria thunbergii, Castanopsis fissa, and other organisms with data available.
Cytidine is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RNA synthesis.
Cytidine is a metabolite found in or produced by Saccharomyces cerevisiae.
A pyrimidine nucleoside that is composed of the base CYTOSINE linked to the five-carbon sugar D-RIBOSE.
A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond.
[Spectral] Cytidine (exact mass = 243.08552) and 3,4-Dihydroxy-L-phenylalanine (exact mass = 197.06881) and NAD+ (exact mass = 663.10912) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
[Spectral] Cytidine (exact mass = 243.08552) and 3,4-Dihydroxy-L-phenylalanine (exact mass = 197.06881) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
[Spectral] Cytidine (exact mass = 243.08552) and S-Adenosyl-L-homocysteine (exact mass = 384.12159) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.

Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[1][2][3].
Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[1][2][3].
Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[1][2][3].

同义名列表

88 个代谢物同义名

4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one; 1-(b-delta-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine; Cytidine, BioReagent, suitable for cell culture, powder, >=99\\%; 1-(beta-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine; 1-(b-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine; 1-(Β-D-ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine; 2(1H)-Pyrimidinone, 4-amino-1-.beta.-D-ribofuranosyl-; 4-Amino-1-beta-delta-ribofuranosyl-2(1H)-pyrimidinone; 4-Amino-1-.beta.-D-ribofuranosyl-2-(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 4-amino-1-beta-D-ribofuranosyl-; 2(1H)-Pyrimidinone, 4-amino-1beta-D-ribofuranosyl-; 4-Amino-1.beta.-D-ribofuranosyl-2(1H)-pyrimidinone; Cytosine -D-riboside;Cytosine-1--D-ribofuranoside; 4-Amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone; 4-amino-1-beta-D-ribofuranosylpyrimidin-2(1H)-one; 4-Amino-1beta-D-ribofuranosyl-2(1H)-pyrimidinone; 1-(beta-D-ribofuranosyl)-4-aminopyrimidin-2-one; 4-Amino-1-β-D-ribofuranosylpyrimidin-2(1H)-one; 4-Amino-1-b-D-ribofuranosylpyrimidin-2(1H)-one; 4-AMINO-1-β-D-ribofuranosyl-2(1H)-pyrimidinone; 4-Amino-1-b-D-ribofuranosyl-2(1H)-pyrimidinone; 4-Amino-1β-D-ribofuranosyl-2(1H)-pyrimidinone; 4-Amino-1b-D-ribofuranosyl-2(1H)-pyrimidinone; 6D2DC474-DD76-4081-8B34-10605C218F49; cytosine-1beta-delta-Ribofuranoside; 1-beta-delta-ribofuranosyl-Cytosine; .beta.-D-Ribofuranoside, cytosine-1; Cytosine, 1-.beta.-D-ribofuranosyl-; 1-beta-delta-Ribofuranosylcytosine; beta-D-Ribofuranoside, cytosine-1; Cytosine, 1-beta-D-ribofuranosyl-; 1beta-2-Ribofuranosylcytosine, d-; 1beta-delta-Ribofuranosylcytosine; cytosine-1b-delta-Ribofuranoside; cytosine-1beta-D-Ribofuranoside; Cytidine; Cytarabine Impurity E; 1.beta.-D-Ribofuranosylcytosine; 1-beta-D-ribofuranosyl-Cytosine; 1-beta-D-Ribofuranosylcytosine; 1-beta-delta-ribosyl-Cytosine; 1.beta.-Ribofuranosylcytosine; Cytosine-1-b-D-ribofuranoside; beta-D-ribofuranosyl-cytidine; 1beta-D-Ribofuranosylcytosine; Cytosine-1β-D-ribofuranoside; cytosine-1b-D-Ribofuranoside; 1-beta-Ribofuranosylcytosine; 1-b-D-Ribofuranosylcytosine; 1-Β-D-ribofuranosylcytosine; 1beta-Ribofuranosylcytosine; 1Β-D-ribofuranosylcytosine; 1b-D-Ribofuranosylcytosine; Cytidine, >=99.0\\% (HPLC); Ribonucleoside, Cytosine; Cytosine-beta-D-riboside; 1-beta-D-ribosyl- (6CI); Cytosine Ribonucleoside; 1-b-D-ribosyl-Cytosine; Cytosine b-D-riboside; Riboside, Cytosine; Cytosine riboside; CYTIDINE [WHO-DD]; CYTIDINE [MART.]; CYTIDINE [INCI]; UNII-5CSZ8459RP; beta.-D-Ribo-C; Cytidine, 99\\%; beta-cytidine; Posilent (TN); CYTIDINE [MI]; 3h-cytidine; 5CSZ8459RP; C9H13N3O5; Cytidine; Posilent; Cytidin; Zytidin; CP-C; CTN; Cyd; Cytidine,cell culture tested; Cytidine; Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside; Cytidine



数据库引用编号

51 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(14)

PlantCyc(4)

代谢反应

611 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(106)

WikiPathways(2)

Plant Reactome(0)

INOH(1)

PlantCyc(480)

COVID-19 Disease Map(2)

PathBank(20)

PharmGKB(0)

88 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 15 AICDA, APOB, APOBEC1, APOBEC3A, APOBEC3B, APOBEC3C, APOBEC3F, APOBEC3G, APOBEC3H, BCL2, DAG1, POMC, PRKX, TYR, UCK2
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 2 APOB, BCL2
Nucleus 10 AICDA, APOBEC1, APOBEC3A, APOBEC3B, APOBEC3C, APOBEC3F, APOBEC3G, APOBEC3H, BCL2, PRKX
cytosol 9 AICDA, APOB, APOBEC3G, APOBEC3H, BCL2, CDA, DAG1, PRKCQ, UCK2
nucleoplasm 6 APOBEC1, APOBEC3A, APOBEC3B, APOBEC3H, DAG1, PRKX
Cell membrane 1 ADRB3
lamellipodium 1 DAG1
Multi-pass membrane protein 1 ADRB3
glutamatergic synapse 1 DAG1
neuronal cell body 1 APOB
sarcolemma 1 DAG1
smooth endoplasmic reticulum 1 APOB
Cytoplasm, cytosol 1 AICDA
Lysosome 1 TYR
plasma membrane 6 ADRB3, APOB, DAG1, GCG, IFNLR1, PRKCQ
Membrane 3 BCL2, DAG1, IFNLR1
basolateral plasma membrane 1 DAG1
extracellular exosome 2 APOB, DAG1
endoplasmic reticulum 1 BCL2
extracellular space 4 APOB, DAG1, GCG, POMC
lysosomal lumen 1 APOB
perinuclear region of cytoplasm 1 TYR
adherens junction 1 DAG1
mitochondrion 1 BCL2
protein-containing complex 2 AICDA, BCL2
intracellular membrane-bounded organelle 3 APOB, DAG1, TYR
filopodium 1 DAG1
Single-pass type I membrane protein 2 IFNLR1, TYR
Secreted 3 APOB, GCG, POMC
extracellular region 5 APOB, CDA, DAG1, GCG, POMC
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
centriolar satellite 1 PRKCQ
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 DAG1
chylomicron 1 APOB
low-density lipoprotein particle 1 APOB
very-low-density lipoprotein particle 1 APOB
Melanosome membrane 1 TYR
Cytoplasm, P-body 3 APOBEC3F, APOBEC3G, APOBEC3H
P-body 7 AICDA, APOBEC3A, APOBEC3B, APOBEC3C, APOBEC3F, APOBEC3G, APOBEC3H
Early endosome 1 APOB
Golgi-associated vesicle 1 TYR
postsynaptic membrane 1 DAG1
Cell membrane, sarcolemma 1 DAG1
pore complex 1 BCL2
focal adhesion 1 DAG1
GABA-ergic synapse 1 DAG1
basement membrane 1 DAG1
collagen-containing extracellular matrix 1 DAG1
secretory granule 1 POMC
Postsynaptic cell membrane 1 DAG1
receptor complex 1 ADRB3
apolipoprotein B mRNA editing enzyme complex 3 APOBEC1, APOBEC3F, APOBEC3G
cytoskeleton 1 DAG1
endosome lumen 1 APOB
Lipid droplet 1 APOB
Nucleus, nucleoplasm 1 DAG1
Melanosome 1 TYR
myelin sheath 1 BCL2
plasma membrane raft 1 DAG1
ficolin-1-rich granule lumen 1 CDA
secretory granule lumen 3 CDA, GCG, POMC
Golgi lumen 1 DAG1
endoplasmic reticulum lumen 3 APOB, DAG1, GCG
tertiary granule lumen 1 CDA
node of Ranvier 1 DAG1
endoplasmic reticulum exit site 1 APOB
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
clathrin-coated endocytic vesicle membrane 1 APOB
ribonucleoprotein complex 2 APOBEC3F, APOBEC3G
costamere 1 DAG1
dystrophin-associated glycoprotein complex 1 DAG1
contractile ring 1 DAG1
postsynaptic cytosol 1 DAG1
mRNA editing complex 1 APOBEC1
nuclear periphery 1 DAG1
endocytic vesicle lumen 1 APOB
[Glucagon-like peptide 1]: Secreted 1 GCG
chylomicron remnant 1 APOB
intermediate-density lipoprotein particle 1 APOB
mature chylomicron 1 APOB
BAD-BCL-2 complex 1 BCL2
photoreceptor ribbon synapse 1 DAG1
interleukin-28 receptor complex 1 IFNLR1
[Beta-dystroglycan]: Cell membrane 1 DAG1
dystroglycan complex 1 DAG1


文献列表

  • Jie Ding, Yang Su, Yinglu Ruan, Nan Li, Qianchao Meng, Jiabang Yang, Li Chen, Chi Liu. Clinical features and outcomes of patients with acute myeloid leukemia: the single-center experience of 668 patients in China. Hematology (Amsterdam, Netherlands). 2024 Dec; 29(1):2310960. doi: 10.1080/16078454.2024.2310960. [PMID: 38323781]
  • David Calderón Guzmán, Norma Osnaya Brizuela, Maribel Ortíz Herrera, Hugo Juárez Olguín, Armando Valenzuela Peraza, Norma Labra Ruíz, Gerardo Barragán Mejía. Intake of oligoelements with cytarabine or etoposide alters dopamine levels and oxidative damage in rat brain. Scientific reports. 2024 05; 14(1):10835. doi: 10.1038/s41598-024-61766-0. [PMID: 38736022]
  • Yan Jia, Xiyu Li, Lulu Chen, Ling Li, Suzhen Zhang, Wenhui Huang, Hao Zhang. AHR signaling pathway mediates mitochondrial oxidative phosphorylation which leads to cytarabine resistance. Acta biochimica et biophysica Sinica. 2024 04; 56(4):597-606. doi: 10.3724/abbs.2024022. [PMID: 38404179]
  • Bei Zheng, Qinqin Zhao, Wenjuan Yang, Pinpin Feng, Chuanwei Xin, Yin Ying, Bo Yang, Bing Han, Jun Zhu, Meiling Zhang, Gonghua Li. Small-molecule antiviral treatments for COVID-19: A systematic review and network meta-analysis. International journal of antimicrobial agents. 2024 Mar; 63(3):107096. doi: 10.1016/j.ijantimicag.2024.107096. [PMID: 38244811]
  • Monika Jamioł, Magdalena Sozoniuk, Jacek Wawrzykowski, Marta Kankofer. Changes in plasma PLAC-1 concentration and its expression during early-mid pregnancy in bovine placental tissues - a pilot study. BMC veterinary research. 2024 Feb; 20(1):59. doi: 10.1186/s12917-024-03898-z. [PMID: 38378537]
  • Nagi M El-Shafai, Yasser S Mostafa, Mohamed S Ramadan, Ibrahim M El-Mehasseb. Enhancement efficiency delivery of antiviral Molnupiravir-drug via the loading with self-assembly nanoparticles of pycnogenol and cellulose which are decorated by zinc oxide nanoparticles for COVID-19 therapy. Bioorganic chemistry. 2024 Feb; 143(?):107028. doi: 10.1016/j.bioorg.2023.107028. [PMID: 38086240]
  • Cody Aplin, Richard A Cerione. Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6. The Journal of biological chemistry. 2023 Dec; 300(2):105608. doi: 10.1016/j.jbc.2023.105608. [PMID: 38159849]
  • Elena Lesch, Maike Simone Stempel, Vanessa Dressnandt, Bastian Oldenkott, Volker Knoop, Mareike Schallenberg-Rüdinger. Conservation of the moss RNA editing factor PPR78 despite the loss of its known C-to-U editing sites is explained by a hidden extra target. The Plant cell. 2023 Nov; ?(?):. doi: 10.1093/plcell/koad292. [PMID: 38000897]
  • Yihan Zhao, Shiqing Jiang, Yujun Tang, Lin Zhao. Venetoclax with CAG regimen for early T-cell precursor acute lymphoblastic leukemia: a case report and literature review. International journal of hematology. 2023 Oct; 118(4):483-488. doi: 10.1007/s12185-023-03623-w. [PMID: 37269505]
  • Chen Wang, Guangming Ma, Shanqi Zhang, Kunhong Zhao, Xiangyang Li. Study on the binding of ningnanmycin to the helicase of Tobamovirus virus. Pesticide biochemistry and physiology. 2023 Aug; 194(?):105494. doi: 10.1016/j.pestbp.2023.105494. [PMID: 37532353]
  • Wenlei Wang, Huijie Liu, Feifei Wang, Xiaoye Liu, Yu Sun, Jie Zhao, Changhua Zhu, Lijun Gan, Jinping Yu, Claus-Peter Witte, Mingjia Chen. N4-acetylation of cytidine in (m)RNA plays essential roles in plants. The Plant cell. 2023 Jun; ?(?):. doi: 10.1093/plcell/koad189. [PMID: 37367221]
  • Bin Li, Donghao Li, Linjun Cai, Qiting Zhou, Cong Liu, Jianzhong Lin, Yixing Li, Xiaoying Zhao, Li Li, Xuanming Liu, Chongsheng He. Transcriptome-wide profiling of RNA N4-cytidine acetylation in Arabidopsis thaliana and Oryza sativa. Molecular plant. 2023 06; 16(6):1082-1098. doi: 10.1016/j.molp.2023.04.009. [PMID: 37073130]
  • Han Yao, Cheng Zhang, Xu Tan, Jieping Li, Xiaolin Yin, Xiaojuan Deng, Ting Chen, Jun Rao, Lei Gao, Peiyan Kong, Xi Zhang. Efficacy and toxicity of CLAG combined with pegylated liposomal doxorubicin in the treatment of refractory or relapsed acute myeloid leukemia. Cancer medicine. 2023 06; 12(11):12377-12387. doi: 10.1002/cam4.5938. [PMID: 37161845]
  • Mi-Rae Park, Hye-Jin Lee, Hye-Min Jang, Nam Hoon Kim, Jun-Seok Lee, Yong Taek Jeong, Inho Kim, Sang-Hyun Choi, Kwan Sik Seo, Dong-Hoon Kim. Cytarabine induces cachexia with lipid malabsorption via zippering the junctions of lacteal in murine small intestine. Journal of lipid research. 2023 06; 64(6):100387. doi: 10.1016/j.jlr.2023.100387. [PMID: 37201659]
  • Zhixin Ma, Wenle Ye, Jinghan Wang, Xin Huang, Jiansong Huang, Xia Li, Chao Hu, Chenying Li, Yile Zhou, Xiangjie Lin, Wenwen Wei, Yu Qian, Yutong Zhou, Shihui Mao, Xiufeng Yin, Bo Zhu, Jie Jin. Glutamate dehydrogenase 1: A novel metabolic target in inhibiting acute myeloid leukaemia progression. British journal of haematology. 2023 May; ?(?):. doi: 10.1111/bjh.18884. [PMID: 37231991]
  • Wei Chu, Ya-Ling Li, Jun-Jie Li, Jia Lin, Mi Li, Jiao Wang, Jian-Zheng He, Yue-Mei Zhang, Juan Yao, Xiao-Jie Jin, Hui Cai, Yong-Qi Liu. Guiqi Baizhu prescription ameliorates cytarabine-induced intestinal mucositis by targeting JAK2 to inhibit M1 macrophage polarization. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 May; 164(?):114902. doi: 10.1016/j.biopha.2023.114902. [PMID: 37209628]
  • Keith Woodley, Laura S Dillingh, George Giotopoulos, Pedro Madrigal, Kevin M Rattigan, Céline Philippe, Vilma Dembitz, Aoife M S Magee, Ryan Asby, Louie N van de Lagemaat, Christopher Mapperley, Sophie C James, Jochen H M Prehn, Konstantinos Tzelepis, Kevin Rouault-Pierre, George S Vassiliou, Kamil R Kranc, G Vignir Helgason, Brian J P Huntly, Paolo Gallipoli. Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death. Nature communications. 2023 04; 14(1):2132. doi: 10.1038/s41467-023-37652-0. [PMID: 37059720]
  • Shuzhen Han, Minghui Xiu, Shuang Li, Yan Shi, Xiaoqian Wang, Xingyao Lin, Hui Cai, Yongqi Liu, Jianzheng He. Exposure to cytarabine causes side effects on adult development and physiology and induces intestinal damage via apoptosis in Drosophila. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Mar; 159(?):114265. doi: 10.1016/j.biopha.2023.114265. [PMID: 36652735]
  • Kaixia Niu, Pengpeng Bai, Junyang Zhang, Xinchi Feng, Feng Qiu. Cytidine Alleviates Dyslipidemia and Modulates the Gut Microbiota Composition in ob/ob Mice. Nutrients. 2023 Feb; 15(5):. doi: 10.3390/nu15051147. [PMID: 36904146]
  • Junjie Yue, Caiting Sun, Jinyuan Tang, Qiyuan Zhang, Mengjie Lou, Hongwen Sun, Lianying Zhang. Downregulation of miRNA-155-5p contributes to the adipogenic activity of 2-ethylhexyl diphenyl phosphate in 3T3-L1 preadipocytes. Toxicology. 2023 Feb; 487(?):153452. doi: 10.1016/j.tox.2023.153452. [PMID: 36764644]
  • Lei Li, Hailong Tian, Zhe Zhang, Ning Ding, Kai He, Shuaijun Lu, Ruolan Liu, Peijie Wu, Yu Wang, Bo He, Maochao Luo, Peilan Peng, Mao Yang, Edouard C Nice, Canhua Huang, Na Xie, Dong Wang, Wei Gao. Carrier-Free Nanoplatform via Evoking Pyroptosis and Immune Response against Breast Cancer. ACS applied materials & interfaces. 2023 Jan; 15(1):452-468. doi: 10.1021/acsami.2c17579. [PMID: 36538368]
  • Ting Li, Jiesen Yu, Mengyuan Hou, Sijie Zha, Qingqing Cheng, Qingshan Zheng, Lujin Li. Quantitative evaluation of therapy options for relapsed/refractory diffuse large B-cell lymphoma: A model-based meta-analysis. Pharmacological research. 2023 01; 187(?):106592. doi: 10.1016/j.phrs.2022.106592. [PMID: 36470547]
  • Wen Wen, Chen Chen, Jiake Tang, Chunyi Wang, Mengyun Zhou, Yongran Cheng, Xiang Zhou, Qi Wu, Xingwei Zhang, Zhanhui Feng, Mingwei Wang, Qin Mao. Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19：a meta-analysis. Annals of medicine. 2022 12; 54(1):516-523. doi: 10.1080/07853890.2022.2034936. [PMID: 35118917]
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