Dauricine (BioDeep_00000000338)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Phenol, 4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)-2-(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-, (R-(R*,R*))-

化学式: C38H44N2O6 (624.3199)
中文名称: 蝙蝠葛碱, 山豆根碱
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 94.59%

分子结构信息

SMILES: CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)OC)O)OC)OC
InChI: InChI=1S/C38H44N2O6/c1-39-15-13-26-20-35(42-3)37(44-5)22-29(26)31(39)17-24-7-10-28(11-8-24)46-34-19-25(9-12-33(34)41)18-32-30-23-38(45-6)36(43-4)21-27(30)14-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3

描述信息

Dauricine is a bisbenzylisoquinoline alkaloid resulting from the formal oxidative dimerisation of 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}phenol by attachment of the phenolic oxygen of one molecule to the benzene ring of the second (ortho to the phenolic hydroxy group of the latter). It has a role as a plant metabolite. It is a tertiary amino compound, a member of phenols, an aromatic ether, a member of isoquinolines and a bisbenzylisoquinoline alkaloid.
Dauricine is a natural product found in Nelumbo nucifera, Menispermum canadense, and Menispermum dauricum with data available.
A bisbenzylisoquinoline alkaloid resulting from the formal oxidative dimerisation of 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}phenol by attachment of the phenolic oxygen of one molecule to the benzene ring of the second (ortho to the phenolic hydroxy group of the latter).
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000077264 - Calcium-Regulating Hormones and Agents
D049990 - Membrane Transport Modulators
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
Dauricine, a bisbenzylisoquinoline alkaloid in Menispermum dauricum, possesses anti-inflammatory activity. Dauricine inhibits cell proliferation and invasion, and induces apoptosis by suppressing NF-κB activation in a dose- and time-dependent manner in colon cancer[1].
Dauricine, a bisbenzylisoquinoline alkaloid in Menispermum dauricum, possesses anti-inflammatory activity. Dauricine inhibits cell proliferation and invasion, and induces apoptosis by suppressing NF-κB activation in a dose- and time-dependent manner in colon cancer[1].

同义名列表

14 个代谢物同义名

Phenol, 4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)-2-(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-, (R-(R*,R*))-; Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-; 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-(4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}phenoxy)phenol; 4-(((1R)-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-1-ISOQUINOLINYL)METHYL)-2-(4-(((1R)-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-1-ISOQUINOLINYL)METHYL)PHENOXY)PHENOL; 4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]phenoxy]phenol; 4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)-2-(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)phenol; dauricine monohydrochloride; 6,6-Di-O-methyldauricoline; UNII-8QTO90G5W5; DAURICINE [MI]; 8QTO90G5W5; Dauricine; 4-[(6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)methyl]-2-[4-[(6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)methyl]phenoxy]phenol; Dauricine



数据库引用编号

24 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ABCB1, ACE2, AIMP2, BCL2, CASP3, CASP9, MTOR, MVD, NFKBIA, PIK3CA, PTGS2, VEGFA
Peripheral membrane protein 3 GORASP1, MTOR, PTGS2
Endoplasmic reticulum membrane 3 BCL2, MTOR, PTGS2
Nucleus 7 AIMP2, BCL2, CASP3, CASP9, MTOR, NFKBIA, VEGFA
cytosol 8 AIMP2, BCL2, CASP3, CASP9, MTOR, MVD, NFKBIA, PIK3CA
dendrite 2 ACVRL1, MTOR
phagocytic vesicle 1 MTOR
nucleoplasm 4 CASP3, MTOR, NFKBIA, SCN5A
Cell membrane 5 ABCB1, ACE2, ACVRL1, SCN5A, TNF
Cytoplasmic side 2 GORASP1, MTOR
lamellipodium 1 PIK3CA
Multi-pass membrane protein 3 ABCB1, CACNA1I, SCN5A
Golgi apparatus membrane 2 GORASP1, MTOR
cell junction 1 SCN5A
cell surface 6 ABCB1, ACE2, ACVRL1, SCN5A, TNF, VEGFA
glutamatergic synapse 1 CASP3
Golgi apparatus 2 GORASP1, VEGFA
Golgi membrane 2 GORASP1, MTOR
lysosomal membrane 1 MTOR
neuronal cell body 3 ACVRL1, CASP3, TNF
sarcolemma 1 SCN5A
Cytoplasm, cytosol 1 AIMP2
Lysosome 1 MTOR
plasma membrane 9 ABCB1, ACE2, ACVRL1, CACNA1I, F2, NFKBIA, PIK3CA, SCN5A, TNF
Membrane 9 ABCB1, ACE2, ACVRL1, AIMP2, BCL2, CACNA1I, MTOR, SCN5A, VEGFA
apical plasma membrane 2 ABCB1, ACE2
caveola 2 PTGS2, SCN5A
extracellular exosome 3 ABCB1, ACE2, F2
Lysosome membrane 1 MTOR
endoplasmic reticulum 4 BCL2, PTGS2, SCN5A, VEGFA
extracellular space 6 ACE2, F2, IL12A, IL6, TNF, VEGFA
perinuclear region of cytoplasm 2 PIK3CA, SCN5A
adherens junction 1 VEGFA
intercalated disc 2 PIK3CA, SCN5A
mitochondrion 2 BCL2, CASP9
protein-containing complex 3 BCL2, CASP9, PTGS2
Microsome membrane 2 MTOR, PTGS2
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 2 ACE2, ACVRL1
Secreted 5 ACE2, F2, IL12A, IL6, VEGFA
extracellular region 6 ACE2, F2, IL12A, IL6, TNF, VEGFA
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, MTOR
Cell projection, cilium 1 ACE2
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
T-tubule 1 SCN5A
Z disc 1 SCN5A
nucleolus 1 SCN5A
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 2 ABCB1, ACE2
Cytoplasm, perinuclear region 1 SCN5A
Membrane raft 2 ACE2, TNF
pore complex 1 BCL2
cis-Golgi network 1 GORASP1
extracellular matrix 1 VEGFA
Nucleus, PML body 1 MTOR
PML body 1 MTOR
collagen-containing extracellular matrix 1 F2
secretory granule 1 VEGFA
lateral plasma membrane 1 SCN5A
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
cilium 1 ACE2
phagocytic cup 1 TNF
brush border membrane 1 ACE2
blood microparticle 1 F2
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
myelin sheath 1 BCL2
Cell membrane, sarcolemma, T-tubule 1 SCN5A
Golgi lumen 1 F2
endoplasmic reticulum lumen 5 ACE2, F2, IL12A, IL6, PTGS2
platelet alpha granule lumen 1 VEGFA
voltage-gated calcium channel complex 1 CACNA1I
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
endocytic vesicle membrane 1 ACE2
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
apoptosome 1 CASP9
external side of apical plasma membrane 1 ABCB1
death-inducing signaling complex 1 CASP3
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
Cytoplasmic vesicle, phagosome 1 MTOR
voltage-gated sodium channel complex 1 SCN5A
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
BMP receptor complex 1 ACVRL1
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
I-kappaB/NF-kappaB complex 1 NFKBIA
interleukin-12 complex 1 IL12A
late endosome lumen 1 IL12A
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
caspase complex 1 CASP9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
[Processed angiotensin-converting enzyme 2]: Secreted 1 ACE2
[Isoform 2]: Apical cell membrane 1 ACE2


文献列表

  • Gan-Qing Xia, Mei-Peng Zhu, Jian-Wen Li, Hui Huang. An alkaloid from Menispermum dauricum, dauricine mediates Ca2+ influx and inhibits NF-κB pathway to protect chondrocytes from IL-1β-induced inflammation and catabolism. Journal of ethnopharmacology. 2024 Mar; 321(?):117560. doi: 10.1016/j.jep.2023.117560. [PMID: 38081396]
  • Lei Xie, Sai Shi, Lin Cheng, Binghong Xu, Sen Ma, Jie Liu, Xilin Wu, Yaxin Wang, Sheng Ye. Dauricine interferes with SARS-CoV-2 variants infection by blocking the interface between RBD and ACE2. International journal of biological macromolecules. 2023 Oct; 253(Pt 7):127344. doi: 10.1016/j.ijbiomac.2023.127344. [PMID: 37848107]
  • Chiwei Peng, Xiang Fu, Kaixuan Wang, Ling Chen, Beijiao Luo, Ni Huang, Yunfeng Luo, Wei Chen. Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells. European journal of pharmacology. 2022 Jan; 914(?):174461. doi: 10.1016/j.ejphar.2021.174461. [PMID: 34469757]
  • Bo Deng, Xiao-Li Jiang, Zhang-Bin Tan, Min Cai, Sui-Hui Deng, Wen-Jun Ding, You-Cai Xu, Yu-Ting Wu, Shuang-Wei Zhang, Rui-Xue Chen, Jun Kan, En-Xin Zhang, Bin Liu, Jing-Zhi Zhang. Dauricine inhibits proliferation and promotes death of melanoma cells via inhibition of Src/STAT3 signaling. Phytotherapy research : PTR. 2021 Jul; 35(7):3836-3847. doi: 10.1002/ptr.7089. [PMID: 33792976]
  • Wencheng Xu, Shuhe Chen, Xiaoqin Wang, Hongguang Wu, Haruki Yamada, Toshihiko Hirano. Bisbenzylisoquinoline alkaloids and P-glycoprotein function: A structure activity relationship study. Bioorganic & medicinal chemistry. 2020 06; 28(12):115553. doi: 10.1016/j.bmc.2020.115553. [PMID: 32503690]
  • Baoru Qiao, Hao Wang, Cheng Wang, Minglu Liang, Kai Huang, Yiqing Li. Dauricine negatively regulates lipopolysaccharide- or cecal ligation and puncture-induced inflammatory response via NF-κB inactivation. Archives of biochemistry and biophysics. 2019 05; 666(?):99-106. doi: 10.1016/j.abb.2019.03.018. [PMID: 30946805]
  • Shu-Rong Ma, Qian Tong, Zhen-Xiong Zhao, Lin Cong, Jin-Bo Yu, Jie Fu, Pei Han, Li-Bin Pan, Randy Gu, Ran Peng, Zheng-Wei Zhang, Yan Wang, Jian-Dong Jiang. Determination of berberine-upregulated endogenous short-chain fatty acids through derivatization by 2-bromoacetophenone. Analytical and bioanalytical chemistry. 2019 May; 411(14):3191-3207. doi: 10.1007/s00216-019-01793-3. [PMID: 30972469]
  • Shuwei Zhang, Yu Ren, Jianxin Qiu. Dauricine inhibits viability and induces cell cycle arrest and apoptosis via inhibiting the PI3K/Akt signaling pathway in renal cell carcinoma cells. Molecular medicine reports. 2018 05; 17(5):7403-7408. doi: 10.3892/mmr.2018.8732. [PMID: 29568902]
  • Pei-Liang Dong, Hua Han, Tian-Yu Zhang, Bingyou Yang, Qiu-Hong Wang, Gao-Wa Eerdun. P‑glycoprotein inhibition increases the transport of dauricine across the blood‑brain barrier. Molecular medicine reports. 2014 Mar; 9(3):985-8. doi: 10.3892/mmr.2013.1880. [PMID: 24378368]
  • Jun Wang, Yuan Li, Xiong-Bing Zu, Min-Feng Chen, Lin Qi. Dauricine can inhibit the activity of proliferation of urinary tract tumor cells. Asian Pacific journal of tropical medicine. 2012 Dec; 5(12):973-6. doi: 10.1016/s1995-7645(12)60185-0. [PMID: 23199717]
  • Jing Zhao, Yong Lian, Chunfeng Lu, Li Jing, Haitao Yuan, Shuangqing Peng. Inhibitory effects of a bisbenzylisoquinline alkaloid dauricine on HERG potassium channels. Journal of ethnopharmacology. 2012 Jun; 141(2):685-91. doi: 10.1016/j.jep.2011.08.054. [PMID: 21920426]
  • Zhengfeng Yang, Chenghai Li, Xiu Wang, Chunyan Zhai, Zhengfang Yi, Lei Wang, Bisheng Liu, Bing Du, Huihui Wu, Xizhi Guo, Mingyao Liu, Dali Li, Jian Luo. Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells. Journal of cellular physiology. 2010 Oct; 225(1):266-75. doi: 10.1002/jcp.22261. [PMID: 20509140]
  • Stella Chai, Kenneth Kw To, Ge Lin. Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines. Chinese medicine. 2010 Jul; 5(?):26. doi: 10.1186/1749-8546-5-26. [PMID: 20653978]
  • Houding Luo, Ming Peng, Haoyu Ye, Lijuan Chen, Aihua Peng, Minghai Tang, Fan Zhang, Jie Shi. Predictable and linear scale-up of four phenolic alkaloids separation from the roots of Menispermum dauricum using high-performance counter-current chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 Jul; 878(22):1929-33. doi: 10.1016/j.jchromb.2010.05.002. [PMID: 20576475]
  • Chao-Zhan Lin, Chen-Chen Zhu, Gui-Hua Deng, Ling Chai, Yao-Bing Li, Yong-Kai Cao, Cui-Xian Zhang, Zhong-Xiang Zhao. [Studies on the chemical constituents of Callicarpa kochiana]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2010 Jun; 33(6):897-900. doi: ". [PMID: 21049609]
  • Xiaoying Liu, Qian Liu, Dongmei Wang, Xueya Wang, Peng Zhang, Haiyan Xu, Hui Zhao, Huaiqing Zhao. Validated liquid chromatography-tandem mass spectrometry method for quantitative determination of dauricine in human plasma and its application to pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 May; 878(15-16):1199-203. doi: 10.1016/j.jchromb.2010.03.028. [PMID: 20371215]
  • Hua Jin, Jieyu Dai, Xiaoyan Chen, Jia Liu, Dafang Zhong, Yansong Gu, Jiang Zheng. Pulmonary toxicity and metabolic activation of dauricine in CD-1 mice. The Journal of pharmacology and experimental therapeutics. 2010 Mar; 332(3):738-46. doi: 10.1124/jpet.109.162297. [PMID: 20008063]
  • Libo Zhao, Xiaomin Wang, Jianhong Wu, Yongsheng Jia, Wenquan Wang, Shaohui Zhang, Jialing Wang. Improved RP-HPLC method to determine neferine in dog plasma and its application to pharmacokinetics. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Oct; 857(2):341-6. doi: 10.1016/j.jchromb.2007.07.043. [PMID: 17707700]
  • F M Han, Z H Peng, W Song, H M Zhang, M M Zhu, Y Chen. Identification of dauricine and its metabolites in rat urine by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Jul; 854(1-2):1-7. doi: 10.1016/j.jchromb.2007.03.036. [PMID: 17448738]
  • Wen-yi Kang, Bai-rang Zhang, Qi-tai Xu, Li Li, Xiao-jiang Hao. [Study on the chemical constituents of Mitragyna rotundifolia]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2006 Jun; 29(6):557-60. doi: ". [PMID: 17039876]
  • Xiang-Ying Kong, Pei-Li Gong. [Effect of phenolic alkaloids of Menispermum dauricum on thrombosis and platelet aggregation]. Yao xue xue bao = Acta pharmaceutica Sinica. 2005 Oct; 40(10):916-9. doi: NULL. [PMID: 16408809]
  • Ihsan Ergün, M Cenk Akbostanci, Başol Canbakan, Bilge Koçer, Arzu Ensari, Gökhan Nergizoglu, Kenan Keven. Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005 Jul; 46(1):e11-4. doi: 10.1053/j.ajkd.2005.03.009. [PMID: 15983949]
  • Ling-Jun Ho, Ting-Yi Juan, Ping Chao, Wan-Lin Wu, Deh-Ming Chang, Sun-Yran Chang, Jenn-Haung Lai. Plant alkaloid tetrandrine downregulates IkappaBalpha kinases-IkappaBalpha-NF-kappaB signaling pathway in human peripheral blood T cell. British journal of pharmacology. 2004 Dec; 143(7):919-27. doi: 10.1038/sj.bjp.0706000. [PMID: 15504755]
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  • Z G Ye, J H Wang, A X Sun, A H Liang, B Y Xue, C Y Li, L Wang. [Poteintation of vincristine-induced apoptosis by tetrandrine, neferine and dauricine in the human mammary MCF-7 multidrug-resistant cells]. Yao xue xue bao = Acta pharmaceutica Sinica. 2001 Feb; 36(2):96-9. doi: . [PMID: 12579872]
  • S Chen, Y Yang, L Zhang, X Pang, Z Dai, F Zeng. A sensitive HPLC technique for the quantitation of dauricine. Journal of Tongji Medical University = Tong ji yi ke da xue xue bao. 2000; 20(1):39-42. doi: 10.1007/bf02887672. [PMID: 12845753]
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  • Y Zhang, D Liu, Y Li. [Effect of dauricine on redistribution of glycoprotein IV in platelet membrane of patients with mitral stenosis]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. 1998 Aug; 18(8):461-3. doi: . [PMID: 11477827]
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  • J A Zhou, W Y Fang, C Wang, J L Zhou, H P Guan. The effects of dauricine and verapamil as calcium channel blockers on the plasma concentration of 6-keto-prostaglandin F1 alpha and thromboxane B2 during cardiopulmonary bypass. The Thoracic and cardiovascular surgeon. 1987 Jun; 35(3):172-5. doi: . [PMID: 2442837]
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  • T Fukushima. [Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 1975 Jul; 71(5):457-62. doi: . [PMID: 280]