Norethindrone (BioDeep_00000003060)

 

Secondary id: BioDeep_00000399166

human metabolite blood metabolite


代谢物信息卡片


(1S,2R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one

化学式: C20H26O2 (298.1933)
中文名称: 炔诺酮
谱图信息: 最多检出来源 Homo sapiens(blood) 14.05%

分子结构信息

SMILES: C#CC1(O)CCC2C3CCC4=CC(=O)CCC4C3CCC21C
InChI: InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1

描述信息

A synthetic progestational hormone with actions similar to those of progesterone but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception. [PubChem]
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4789; ORIGINAL_PRECURSOR_SCAN_NO 4788
INTERNAL_ID 429; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9046; ORIGINAL_PRECURSOR_SCAN_NO 9044
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9061; ORIGINAL_PRECURSOR_SCAN_NO 9058
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9106; ORIGINAL_PRECURSOR_SCAN_NO 9102
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9046; ORIGINAL_PRECURSOR_SCAN_NO 9044
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9063; ORIGINAL_PRECURSOR_SCAN_NO 9058
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4892; ORIGINAL_PRECURSOR_SCAN_NO 4890
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4826; ORIGINAL_PRECURSOR_SCAN_NO 4825
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4801; ORIGINAL_PRECURSOR_SCAN_NO 4798
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4810; ORIGINAL_PRECURSOR_SCAN_NO 4809
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9085; ORIGINAL_PRECURSOR_SCAN_NO 9082
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4809; ORIGINAL_PRECURSOR_SCAN_NO 4806
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03A - Hormonal contraceptives for systemic use > G03AC - Progestogens
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03D - Progestogens > G03DC - Estren derivatives
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
CONFIDENCE standard compound; INTERNAL_ID 2798
CONFIDENCE standard compound; INTERNAL_ID 4150

同义名列表

147 个代谢物同义名

(1S,2R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one; (17alpha)-17-Ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one; 19-Nor-17-alpha-ethynyl-17-beta-hydroxy-4-androsten-3-one; 19-Nor-17alpha-ethynyl-17beta-hydroxy-4-androsten-3-one; 17alpha-Ethynyl-17beta-hydroxy-19-norandrost-4-en-3-one; (17Α)-17-ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one; (17a)-17-Ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one; 17-alpha-Ethynyl-19-norandrost-4-en-17-beta-ol-3-one; 17-Ethynyl-17-hydroxyestr-4-en-3-one (acd/name 4.0); 19-Nor-17-α-ethynyl-17-β-hydroxy-4-androsten-3-one; (17-alpha)-17-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17alpha-Ethynyl-19-norandrost-4-en-17beta-ol-3-one; 17alpha-Ethynyl-19-nor-4-androsten-17beta-ol-3-one; 19-Nor-17-a-ethynyl-17-b-hydroxy-4-androsten-3-one; 17alpha-Ethinyl-17alpha-ethinyl-19-nortestosterone; 17-Hydroxy-19-nor-17-alpha-pregn-4-en-20-yn-3-one; 19-Nor-17-alpha-ethynylandrosten-17-beta-ol-3-one; 17-Hydroxy-(17alpha)-19-norpregn-4-en-20-yn-3-one; 17-Hydroxy-19-nor-17alpha-pregn-4-en-20-yn-3-one; 17a-Ethynyl-17b-hydroxy-19-norandrost-4-en-3-one; 17-Hydroxy-17-alpha-19-norpregn-4-en-20-yn-3-one; 19-Nor-17α-ethynyl-17β-hydroxy-4-androsten-3-one; 19-Nor-17a-ethynyl-17b-hydroxy-4-androsten-3-one; 17Α-ethynyl-17β-hydroxy-19-norandrost-4-en-3-one; 19-Nor-17alpha-ethynylandrosten-17beta-ol-3-one; 17-alpha-Ethynyl-17-beta-hydroxy-4-estren-3-one; 17-Hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one; 17beta-Hydroxy-17alpha-ethynylestr-4-en-3-one; 17alpha-Ethynyl-17beta-hydroxyestr-4-en-3-one; 17-Α-ethynyl-19-norandrost-4-en-17-β-ol-3-one; 17-Hydroxy-19-nor-17-a-pregn-4-en-20-yn-3-one; 17-a-Ethynyl-19-norandrost-4-en-17-b-ol-3-one; 17-Hydroxy-19-nor-17a-pregn-4-en-20-yn-3-one; 17alpha-hydroxy-19-norpregn-4-en-20-yn-3-one; 17-Hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one; 17-beta-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17Α-ethynyl-19-nor-4-androsten-17β-ol-3-one; 17beta-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17a-Ethynyl-19-nor-4-androsten-17b-ol-3-one; 17a-Ethynyl-19-norandrost-4-en-17b-ol-3-one; 17Α-ethynyl-19-norandrost-4-en-17β-ol-3-one; 19-Nor-17-a-ethynylandrosten-17-b-ol-3-one; 19-Nor-17-α-ethynylandrosten-17-β-ol-3-one; 17-alpha-Ethynyl-17-hydroxy-4-estren-3-one; 17alpha-Ethynyl-17-hydroxy-estr-4-en-3-one; 17alpha-Ethinylestra-4-en-17beta-ol-3-one; 17-Β-hydroxy-19-norpregn-4-en-20-yn-3-one; 17alpha-Ethynyl-17-hydroxy-4-estren-3-one; 17-b-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17alpha-Ethynyl-3-oxo-4-estren-17beta-ol; 17Β-hydroxy-19-norpregn-4-en-20-yn-3-one; 4-Estren-17alpha-ethynyl-17beta-ol-3-one; 19-Nor-17a-ethynylandrosten-17b-ol-3-one; 17b-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17alpha-Ethynyl-17-hydroxyest-4-en-3-one; 19-Nor-17α-ethynylandrosten-17β-ol-3-one; 17-Ethynyl-17beta-hydroxyestr-4-en-3-one; 17-a-Ethynyl-17-hydroxy-4-estren-3-one; 17-Α-ethynyl-17-hydroxy-4-estren-3-one; 17-alpha-Ethynyl-4-estren-17-ol-3-one; 17a-Ethynyl-17-hydroxy-4-estren-3-one; 17Α-ethynyl-17-hydroxy-4-estren-3-one; 17alpha-Ethynyl-4-estren-17-ol-3-one; 19-Nor-17-alpha-ethynyltestosterone; 17-alpha-Ethynyl-19-nortestosterone; 17Α-ethinylestra-4-en-17β-ol-3-one; 17alpha-Ethynyl-19-nortestosterone; 19-Nor-17alpha-ethynyltestosterone; 17a-Ethinylestra-4-en-17b-ol-3-one; 17alpha-Ethinyl-19-nortestosterone; 4-Estren-17a-ethynyl-17b-ol-3-one; 17-a-Ethynyl-4-estren-17-ol-3-one; 4-Estren-17α-ethynyl-17β-ol-3-one; 17-Α-ethynyl-4-estren-17-ol-3-one; 17a-Ethynyl-4-estren-17-ol-3-one; 17Α-ethynyl-4-estren-17-ol-3-one; 17-a-Ethynyl-19-nortestosterone; 17-Α-ethynyl-19-nortestosterone; 19-Nor-17-a-ethynyltestosterone; 19-Nor-17-α-ethynyltestosterone; 17Α-ethinyl-19-nortestosterone; 17a-Ethinyl-19-nortestosterone; 17a-Ethynyl-19-nortestosterone; 17-Ethinyl-19-nor-testosterone; 17alpha-Pregn-4-en-20-yn-3-one; 19-Nor-17a-ethynyltestosterone; Norethindrone, (1 beta)-isomer; Norethisterone / norethindrone; 17Α-ethynyl-19-nortestosterone; 19-Nor-17α-ethynyltestosterone; Anhydrohydroxynorprogesterone; 19-Nor-17-ethinyltestosterone; 17-Ethynyl-19-nortestosterone; Ethinyl-19-nortestosterone; 19-Norethinyltestosterone; Ethynylnortestosterone; Ethinylnortestosterone; Norpregneninolone; 19-Norethisterone; 19-Nor-ethindrone; Norpregneninlone; Norethisteronum; Noresthisterone; Norethisterone; Norethynodrone; Norethisteron; Noretisterona; Norethindrone; Norethyndron; Primolut N; Primolut-N; ST 20:4;O2; Proluteasi; Micronovum; Normapause; Noralutin; Norlutate; Mini-pill; Conceplan; Norcolute; Norgestin; Micronett; Monogest; Norcolut; Minovlar; Norluten; Conludaf; Norlutin; Micronor; Conludag; Norluton; Nor-q.d.; Mini-pe; Utovlan; Noriday; Gestest; Utovlar; Anovule; Nor QD; Norfor; Menzol; Camila; Nor-QD; NorQD; NET; ENT; Norethindrone



数据库引用编号

42 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, AR, BGLAP, CYP3A4, ESR1, NR3C1, PGR, TRPC6, VEGFA
Peripheral membrane protein 1 ESR1
Endoplasmic reticulum membrane 3 CYP19A1, CYP3A4, PGRMC1
Nucleus 6 ALB, AR, ESR1, NR3C1, PGR, VEGFA
cytosol 6 ALB, APOA1, AR, ESR1, NR3C1, PGR
dendrite 1 BGLAP
centrosome 2 ALB, NR3C1
nucleoplasm 4 AR, ESR1, NR3C1, PGR
Cell membrane 2 ESR1, TRPC6
Cytoplasmic side 1 ESR1
Multi-pass membrane protein 2 CYP19A1, TRPC6
Synapse 2 NR3C1, PGRMC1
cell surface 2 PLG, VEGFA
glutamatergic synapse 1 PLG
Golgi apparatus 3 ALB, ESR1, VEGFA
Golgi membrane 1 INS
neuronal cell body 1 PGRMC1
plasma membrane 9 APOA1, AR, ESR1, F2, PGR, PGRMC1, PLG, REN, TRPC6
Membrane 9 AR, CYP19A1, CYP3A4, ESR1, NR3C1, PGRMC1, REN, TRPC6, VEGFA
extracellular exosome 5 ALB, APOA1, F2, PLG, SHBG
endoplasmic reticulum 4 ALB, CYP19A1, PGRMC1, VEGFA
extracellular space 11 ALB, APOA1, BGLAP, F2, GNRH1, INS, LPA, PLG, PTH, REN, VEGFA
Schaffer collateral - CA1 synapse 1 PLG
adherens junction 1 VEGFA
mitochondrion 1 NR3C1
protein-containing complex 4 ALB, AR, ESR1, NR3C1
intracellular membrane-bounded organelle 1 CYP3A4
Microsome membrane 3 CYP19A1, CYP3A4, PGRMC1
Secreted 10 ALB, APOA1, BGLAP, F2, INS, PGRMC1, PLG, REN, SHBG, VEGFA
extracellular region 13 ALB, APOA1, BGLAP, F2, GNRH1, INS, LPA, PGRMC1, PLG, PTH, REN, SHBG, VEGFA
Mitochondrion outer membrane 1 PGRMC1
Single-pass membrane protein 1 PGRMC1
mitochondrial outer membrane 2 PGR, PGRMC1
mitochondrial matrix 1 NR3C1
Extracellular side 1 PGRMC1
anchoring junction 1 ALB
transcription regulator complex 1 ESR1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 NR3C1
external side of plasma membrane 1 PLG
Extracellular vesicle 1 APOA1
Secreted, extracellular space, extracellular matrix 1 VEGFA
chylomicron 1 APOA1
high-density lipoprotein particle 1 APOA1
low-density lipoprotein particle 1 APOA1
very-low-density lipoprotein particle 1 APOA1
perikaryon 1 BGLAP
slit diaphragm 1 TRPC6
cytoplasmic vesicle 1 APOA1
Early endosome 1 APOA1
apical part of cell 1 REN
vesicle 1 BGLAP
Cytoplasm, cytoskeleton, spindle 1 NR3C1
spindle 1 NR3C1
extracellular matrix 1 VEGFA
collagen-containing extracellular matrix 3 APOA1, F2, PLG
secretory granule 1 VEGFA
nuclear speck 2 AR, NR3C1
neuron projection 1 PGRMC1
ciliary basal body 1 ALB
chromatin 4 AR, ESR1, NR3C1, PGR
Chromosome 1 NR3C1
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 4 ALB, APOA1, F2, PLG
Endomembrane system 1 PGRMC1
endosome lumen 1 INS
Nucleus, nucleoplasm 1 NR3C1
specific granule membrane 1 PGRMC1
euchromatin 1 ESR1
Smooth endoplasmic reticulum membrane 1 PGRMC1
cell body 1 PGRMC1
secretory granule lumen 2 APOA1, INS
Golgi lumen 3 BGLAP, F2, INS
endoplasmic reticulum lumen 5 ALB, APOA1, BGLAP, F2, INS
platelet alpha granule lumen 3 ALB, PLG, VEGFA
endocytic vesicle 1 APOA1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
[Isoform 1]: Nucleus 1 ESR1
[Isoform Alpha]: Cytoplasm 1 NR3C1
spherical high-density lipoprotein particle 1 APOA1
endocytic vesicle lumen 1 APOA1
[Isoform Beta]: Nucleus 1 NR3C1
[Isoform Alpha-B]: Nucleus 1 NR3C1
[Isoform 4]: Mitochondrion outer membrane 1 PGR
plasma lipoprotein particle 1 LPA
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
cation channel complex 1 TRPC6
ciliary transition fiber 1 ALB


文献列表

  • Ishani Landry, Jagadeesh Aluri, Nancy Hall, Gleb Filippov, Satish Dayal, Margaret Moline, Larisa Reyderman. Effects of Lemborexant on the Pharmacokinetics of Oral Contraceptives: Results From a Phase 1 Drug-Drug Interaction Study in Healthy Females. Clinical pharmacology in drug development. 2021 09; 10(9):1089-1098. doi: 10.1002/cpdd.953. [PMID: 34107159]
  • Refilwe P Molatlhegi, Samkelisiwe Ngcobo, Lenine J P Liebenberg, Sinaye Ngcapu, Amanda Mabhula, Alasdair Leslie, Nobuhle Mchunu, Mthobisi M Zondi, John H Adamson, Katya Govender, Natasha Samsunder, Salim S Abdool Karim, Quarraisha Abdool Karim, Jo-Ann S Passmore, Aida Sivro, Lyle R McKinnon. Genital and systemic immune effects of the injectable, contraceptive norethisterone enanthate (NET-EN), in South African women. American journal of reproductive immunology (New York, N.Y. : 1989). 2021 08; 86(2):e13411. doi: 10.1111/aji.13411. [PMID: 33641222]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Smritee Dabee, Ramla F Tanko, Bryan P Brown, Rubina Bunjun, Christina Balle, Colin Feng, Iyaloo N Konstantinus, Shameem Z Jaumdally, Maricianah Onono, Gonasagrie Nair, Thesla Palanee-Phillips, Katherine Gill, Jared M Baeten, Linda-Gail Bekker, Jo-Ann S Passmore, Renee Heffron, Heather B Jaspan, Anna-Ursula Happel. Comparison of Female Genital Tract Cytokine and Microbiota Signatures Induced by Initiation of Intramuscular DMPA and NET-EN Hormonal Contraceptives - a Prospective Cohort Analysis. Frontiers in immunology. 2021; 12(?):760504. doi: 10.3389/fimmu.2021.760504. [PMID: 34956191]
  • Liping Hou, Shanduo Chen, Wenjun Shi, Hongxing Chen, Yanqiu Liang, Xiaolan Wang, Jiefeng Tan, Yifan Wang, Xikai Deng, Manjun Zhan, Jianzhao Long, Guowei Cai, Shaowen Luo, Cuiping Zhang, Juan Liu, Jonathan Y S Leung, Lingtian Xie. Norethindrone alters mating behaviors, ovary histology, hormone production and transcriptional expression of steroidogenic genes in zebrafish (Danio rerio). Ecotoxicology and environmental safety. 2020 Jun; 195(?):110496. doi: 10.1016/j.ecoenv.2020.110496. [PMID: 32213369]
  • Bob Gray, Lisa Tuckley, Charlotte Cutler, Simon Biddle, Simon Hudson, Simon Gower, Lynn Vanhaecke. Investigations into the analysis of intact drug conjugates in animal sport doping control - Development and assessment of a rapid and economical approach for screening greyhound urine. Drug testing and analysis. 2020 Jun; 12(6):731-742. doi: 10.1002/dta.2779. [PMID: 32052913]
  • Payal Trupti Kotecha, Ian F Godsland, David Crook, John C Stevenson. Effects of tibolone or continuous combined oestradiol and norethisterone acetate on lipids, high-density lipoprotein subfractions and apolipoproteins in postmenopausal women in a two-year, randomized, double-blind, placebo-controlled trial. Clinical endocrinology. 2020 04; 92(4):303-311. doi: 10.1111/cen.14155. [PMID: 31925799]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Leo Han, Emily Padua, Kyle D Hart, Alison Edelman, Jeffrey T Jensen. Comparing cervical mucus changes in response to an oral progestin or oestrogen withdrawal in ovarian-suppressed women: a clinical pilot. The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception. 2019 Jun; 24(3):209-215. doi: 10.1080/13625187.2019.1605503. [PMID: 31066303]
  • Jessica K Hartman, Tyler Beames, Bethany Parks, Daniel Doheny, Gina Song, Alina Efremenko, Miyoung Yoon, Briana Foley, Chad Deisenroth, Patrick D McMullen, Rebecca A Clewell. An in vitro approach for prioritization and evaluation of chemical effects on glucocorticoid receptor mediated adipogenesis. Toxicology and applied pharmacology. 2018 09; 355(?):112-126. doi: 10.1016/j.taap.2018.05.016. [PMID: 29782964]
  • Christian Friedrich, Matthias Berse, Stefan Klein, Beate Rohde, Joachim Höchel. In Vivo Formation of Ethinylestradiol After Intramuscular Administration of Norethisterone Enantate. Journal of clinical pharmacology. 2018 06; 58(6):781-789. doi: 10.1002/jcph.1079. [PMID: 29522253]
  • Alison C Bryant-Smith, Anne Lethaby, Cindy Farquhar, Martha Hickey. Antifibrinolytics for heavy menstrual bleeding. The Cochrane database of systematic reviews. 2018 04; 4(?):CD000249. doi: 10.1002/14651858.cd000249.pub2. [PMID: 29656433]
  • Weiguo Xie, Xiaohu Ge, Ling Li, Athena Yao, Xiaoyan Wang, Min Li, Xiang Gong, Zhigang Chu, Zhe Lu, Xiaodong Huang, Yun Jiao, Yifei Wang, Meifang Xiao, Haijia Chen, Wei Xiang, Paul Yao. Resveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation. Molecular autism. 2018; 9(?):43. doi: 10.1186/s13229-018-0225-5. [PMID: 30123446]
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