Norethindrone (BioDeep_00000003060)

 

Secondary id: BioDeep_00000399166

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


(1S,2R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one

化学式: C20H26O2 (298.1932696)
中文名称: 炔诺酮
谱图信息: 最多检出来源 Homo sapiens(blood) 1.97%

分子结构信息

SMILES: C#CC1(O)CCC2C3CCC4=CC(=O)CCC4C3CCC21C
InChI: InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1

描述信息

A synthetic progestational hormone with actions similar to those of progesterone but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception. [PubChem]
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4789; ORIGINAL_PRECURSOR_SCAN_NO 4788
INTERNAL_ID 429; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9046; ORIGINAL_PRECURSOR_SCAN_NO 9044
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9061; ORIGINAL_PRECURSOR_SCAN_NO 9058
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9106; ORIGINAL_PRECURSOR_SCAN_NO 9102
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9046; ORIGINAL_PRECURSOR_SCAN_NO 9044
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9063; ORIGINAL_PRECURSOR_SCAN_NO 9058
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4892; ORIGINAL_PRECURSOR_SCAN_NO 4890
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4826; ORIGINAL_PRECURSOR_SCAN_NO 4825
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4801; ORIGINAL_PRECURSOR_SCAN_NO 4798
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4810; ORIGINAL_PRECURSOR_SCAN_NO 4809
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9085; ORIGINAL_PRECURSOR_SCAN_NO 9082
CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4809; ORIGINAL_PRECURSOR_SCAN_NO 4806
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03A - Hormonal contraceptives for systemic use > G03AC - Progestogens
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03D - Progestogens > G03DC - Estren derivatives
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
CONFIDENCE standard compound; INTERNAL_ID 2798
CONFIDENCE standard compound; INTERNAL_ID 4150

同义名列表

147 个代谢物同义名

(1S,2R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one; (17alpha)-17-Ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one; 19-Nor-17-alpha-ethynyl-17-beta-hydroxy-4-androsten-3-one; 19-Nor-17alpha-ethynyl-17beta-hydroxy-4-androsten-3-one; 17alpha-Ethynyl-17beta-hydroxy-19-norandrost-4-en-3-one; (17Α)-17-ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one; (17a)-17-Ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one; 17-alpha-Ethynyl-19-norandrost-4-en-17-beta-ol-3-one; 17-Ethynyl-17-hydroxyestr-4-en-3-one (acd/name 4.0); 19-Nor-17-α-ethynyl-17-β-hydroxy-4-androsten-3-one; (17-alpha)-17-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17alpha-Ethynyl-19-norandrost-4-en-17beta-ol-3-one; 17alpha-Ethynyl-19-nor-4-androsten-17beta-ol-3-one; 19-Nor-17-a-ethynyl-17-b-hydroxy-4-androsten-3-one; 17alpha-Ethinyl-17alpha-ethinyl-19-nortestosterone; 17-Hydroxy-19-nor-17-alpha-pregn-4-en-20-yn-3-one; 19-Nor-17-alpha-ethynylandrosten-17-beta-ol-3-one; 17-Hydroxy-(17alpha)-19-norpregn-4-en-20-yn-3-one; 17-Hydroxy-19-nor-17alpha-pregn-4-en-20-yn-3-one; 17a-Ethynyl-17b-hydroxy-19-norandrost-4-en-3-one; 17-Hydroxy-17-alpha-19-norpregn-4-en-20-yn-3-one; 19-Nor-17α-ethynyl-17β-hydroxy-4-androsten-3-one; 19-Nor-17a-ethynyl-17b-hydroxy-4-androsten-3-one; 17Α-ethynyl-17β-hydroxy-19-norandrost-4-en-3-one; 19-Nor-17alpha-ethynylandrosten-17beta-ol-3-one; 17-alpha-Ethynyl-17-beta-hydroxy-4-estren-3-one; 17-Hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one; 17beta-Hydroxy-17alpha-ethynylestr-4-en-3-one; 17alpha-Ethynyl-17beta-hydroxyestr-4-en-3-one; 17-Α-ethynyl-19-norandrost-4-en-17-β-ol-3-one; 17-Hydroxy-19-nor-17-a-pregn-4-en-20-yn-3-one; 17-a-Ethynyl-19-norandrost-4-en-17-b-ol-3-one; 17-Hydroxy-19-nor-17a-pregn-4-en-20-yn-3-one; 17alpha-hydroxy-19-norpregn-4-en-20-yn-3-one; 17-Hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one; 17-beta-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17Α-ethynyl-19-nor-4-androsten-17β-ol-3-one; 17beta-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17a-Ethynyl-19-nor-4-androsten-17b-ol-3-one; 17a-Ethynyl-19-norandrost-4-en-17b-ol-3-one; 17Α-ethynyl-19-norandrost-4-en-17β-ol-3-one; 19-Nor-17-a-ethynylandrosten-17-b-ol-3-one; 19-Nor-17-α-ethynylandrosten-17-β-ol-3-one; 17-alpha-Ethynyl-17-hydroxy-4-estren-3-one; 17alpha-Ethynyl-17-hydroxy-estr-4-en-3-one; 17alpha-Ethinylestra-4-en-17beta-ol-3-one; 17-Β-hydroxy-19-norpregn-4-en-20-yn-3-one; 17alpha-Ethynyl-17-hydroxy-4-estren-3-one; 17-b-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17alpha-Ethynyl-3-oxo-4-estren-17beta-ol; 17Β-hydroxy-19-norpregn-4-en-20-yn-3-one; 4-Estren-17alpha-ethynyl-17beta-ol-3-one; 19-Nor-17a-ethynylandrosten-17b-ol-3-one; 17b-Hydroxy-19-norpregn-4-en-20-yn-3-one; 17alpha-Ethynyl-17-hydroxyest-4-en-3-one; 19-Nor-17α-ethynylandrosten-17β-ol-3-one; 17-Ethynyl-17beta-hydroxyestr-4-en-3-one; 17-a-Ethynyl-17-hydroxy-4-estren-3-one; 17-Α-ethynyl-17-hydroxy-4-estren-3-one; 17-alpha-Ethynyl-4-estren-17-ol-3-one; 17a-Ethynyl-17-hydroxy-4-estren-3-one; 17Α-ethynyl-17-hydroxy-4-estren-3-one; 17alpha-Ethynyl-4-estren-17-ol-3-one; 19-Nor-17-alpha-ethynyltestosterone; 17-alpha-Ethynyl-19-nortestosterone; 17Α-ethinylestra-4-en-17β-ol-3-one; 17alpha-Ethynyl-19-nortestosterone; 19-Nor-17alpha-ethynyltestosterone; 17a-Ethinylestra-4-en-17b-ol-3-one; 17alpha-Ethinyl-19-nortestosterone; 4-Estren-17a-ethynyl-17b-ol-3-one; 17-a-Ethynyl-4-estren-17-ol-3-one; 4-Estren-17α-ethynyl-17β-ol-3-one; 17-Α-ethynyl-4-estren-17-ol-3-one; 17a-Ethynyl-4-estren-17-ol-3-one; 17Α-ethynyl-4-estren-17-ol-3-one; 17-a-Ethynyl-19-nortestosterone; 17-Α-ethynyl-19-nortestosterone; 19-Nor-17-a-ethynyltestosterone; 19-Nor-17-α-ethynyltestosterone; 17Α-ethinyl-19-nortestosterone; 17a-Ethinyl-19-nortestosterone; 17a-Ethynyl-19-nortestosterone; 17-Ethinyl-19-nor-testosterone; 17alpha-Pregn-4-en-20-yn-3-one; 19-Nor-17a-ethynyltestosterone; Norethindrone, (1 beta)-isomer; Norethisterone / norethindrone; 17Α-ethynyl-19-nortestosterone; 19-Nor-17α-ethynyltestosterone; Anhydrohydroxynorprogesterone; 19-Nor-17-ethinyltestosterone; 17-Ethynyl-19-nortestosterone; Ethinyl-19-nortestosterone; 19-Norethinyltestosterone; Ethynylnortestosterone; Ethinylnortestosterone; Norpregneninolone; 19-Norethisterone; 19-Nor-ethindrone; Norpregneninlone; Norethisteronum; Noresthisterone; Norethisterone; Norethynodrone; Norethisteron; Noretisterona; Norethindrone; Norethyndron; Primolut N; Primolut-N; ST 20:4;O2; Proluteasi; Micronovum; Normapause; Noralutin; Norlutate; Mini-pill; Conceplan; Norcolute; Norgestin; Micronett; Monogest; Norcolut; Minovlar; Norluten; Conludaf; Norlutin; Micronor; Conludag; Norluton; Nor-q.d.; Mini-pe; Utovlan; Noriday; Gestest; Utovlar; Anovule; Nor QD; Norfor; Menzol; Camila; Nor-QD; NorQD; NET; ENT; Norethindrone



数据库引用编号

42 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ishani Landry, Jagadeesh Aluri, Nancy Hall, Gleb Filippov, Satish Dayal, Margaret Moline, Larisa Reyderman. Effects of Lemborexant on the Pharmacokinetics of Oral Contraceptives: Results From a Phase 1 Drug-Drug Interaction Study in Healthy Females. Clinical pharmacology in drug development. 2021 09; 10(9):1089-1098. doi: 10.1002/cpdd.953. [PMID: 34107159]
  • Refilwe P Molatlhegi, Samkelisiwe Ngcobo, Lenine J P Liebenberg, Sinaye Ngcapu, Amanda Mabhula, Alasdair Leslie, Nobuhle Mchunu, Mthobisi M Zondi, John H Adamson, Katya Govender, Natasha Samsunder, Salim S Abdool Karim, Quarraisha Abdool Karim, Jo-Ann S Passmore, Aida Sivro, Lyle R McKinnon. Genital and systemic immune effects of the injectable, contraceptive norethisterone enanthate (NET-EN), in South African women. American journal of reproductive immunology (New York, N.Y. : 1989). 2021 08; 86(2):e13411. doi: 10.1111/aji.13411. [PMID: 33641222]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Smritee Dabee, Ramla F Tanko, Bryan P Brown, Rubina Bunjun, Christina Balle, Colin Feng, Iyaloo N Konstantinus, Shameem Z Jaumdally, Maricianah Onono, Gonasagrie Nair, Thesla Palanee-Phillips, Katherine Gill, Jared M Baeten, Linda-Gail Bekker, Jo-Ann S Passmore, Renee Heffron, Heather B Jaspan, Anna-Ursula Happel. Comparison of Female Genital Tract Cytokine and Microbiota Signatures Induced by Initiation of Intramuscular DMPA and NET-EN Hormonal Contraceptives - a Prospective Cohort Analysis. Frontiers in immunology. 2021; 12(?):760504. doi: 10.3389/fimmu.2021.760504. [PMID: 34956191]
  • Liping Hou, Shanduo Chen, Wenjun Shi, Hongxing Chen, Yanqiu Liang, Xiaolan Wang, Jiefeng Tan, Yifan Wang, Xikai Deng, Manjun Zhan, Jianzhao Long, Guowei Cai, Shaowen Luo, Cuiping Zhang, Juan Liu, Jonathan Y S Leung, Lingtian Xie. Norethindrone alters mating behaviors, ovary histology, hormone production and transcriptional expression of steroidogenic genes in zebrafish (Danio rerio). Ecotoxicology and environmental safety. 2020 Jun; 195(?):110496. doi: 10.1016/j.ecoenv.2020.110496. [PMID: 32213369]
  • Bob Gray, Lisa Tuckley, Charlotte Cutler, Simon Biddle, Simon Hudson, Simon Gower, Lynn Vanhaecke. Investigations into the analysis of intact drug conjugates in animal sport doping control - Development and assessment of a rapid and economical approach for screening greyhound urine. Drug testing and analysis. 2020 Jun; 12(6):731-742. doi: 10.1002/dta.2779. [PMID: 32052913]
  • Payal Trupti Kotecha, Ian F Godsland, David Crook, John C Stevenson. Effects of tibolone or continuous combined oestradiol and norethisterone acetate on lipids, high-density lipoprotein subfractions and apolipoproteins in postmenopausal women in a two-year, randomized, double-blind, placebo-controlled trial. Clinical endocrinology. 2020 04; 92(4):303-311. doi: 10.1111/cen.14155. [PMID: 31925799]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Leo Han, Emily Padua, Kyle D Hart, Alison Edelman, Jeffrey T Jensen. Comparing cervical mucus changes in response to an oral progestin or oestrogen withdrawal in ovarian-suppressed women: a clinical pilot. The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception. 2019 Jun; 24(3):209-215. doi: 10.1080/13625187.2019.1605503. [PMID: 31066303]
  • Jessica K Hartman, Tyler Beames, Bethany Parks, Daniel Doheny, Gina Song, Alina Efremenko, Miyoung Yoon, Briana Foley, Chad Deisenroth, Patrick D McMullen, Rebecca A Clewell. An in vitro approach for prioritization and evaluation of chemical effects on glucocorticoid receptor mediated adipogenesis. Toxicology and applied pharmacology. 2018 09; 355(?):112-126. doi: 10.1016/j.taap.2018.05.016. [PMID: 29782964]
  • Christian Friedrich, Matthias Berse, Stefan Klein, Beate Rohde, Joachim Höchel. In Vivo Formation of Ethinylestradiol After Intramuscular Administration of Norethisterone Enantate. Journal of clinical pharmacology. 2018 06; 58(6):781-789. doi: 10.1002/jcph.1079. [PMID: 29522253]
  • Alison C Bryant-Smith, Anne Lethaby, Cindy Farquhar, Martha Hickey. Antifibrinolytics for heavy menstrual bleeding. The Cochrane database of systematic reviews. 2018 04; 4(?):CD000249. doi: 10.1002/14651858.cd000249.pub2. [PMID: 29656433]
  • Weiguo Xie, Xiaohu Ge, Ling Li, Athena Yao, Xiaoyan Wang, Min Li, Xiang Gong, Zhigang Chu, Zhe Lu, Xiaodong Huang, Yun Jiao, Yifei Wang, Meifang Xiao, Haijia Chen, Wei Xiang, Paul Yao. Resveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation. Molecular autism. 2018; 9(?):43. doi: 10.1186/s13229-018-0225-5. [PMID: 30123446]
  • Michelle F Maritz, Roslyn M Ray, Alexis J Bick, Michele Tomasicchio, John G Woodland, Yashini Govender, Chanel Avenant, Janet P Hapgood. Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels. PloS one. 2018; 13(4):e0196043. doi: 10.1371/journal.pone.0196043. [PMID: 29698514]
  • Karen L Middlemiss, Denham G Cook, Alistair R Jerrett, William Davison. Morphology and hydro-sensory role of superficial neuromasts in schooling behaviour of yellow-eyed mullet (Aldrichetta forsteri). Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 2017 Oct; 203(10):807-817. doi: 10.1007/s00359-017-1192-6. [PMID: 28600601]
  • Jennifer E Balkus, Thesla Palanee-Phillips, Krishnaveni Reddy, Samantha Siva, Ishana Harkoo, Clemensia Nakabiito, Kenneth Kintu, Gonasangrie Nair, Catherine Chappell, Flavia Matovu Kiweewa, Samuel Kabwigu, Logashvari Naidoo, Nitesha Jeenarain, Mark Marzinke, Lydia Soto-Torres, Elizabeth R Brown, Jared M Baeten. Brief Report: Dapivirine Vaginal Ring Use Does Not Diminish the Effectiveness of Hormonal Contraception. Journal of acquired immune deficiency syndromes (1999). 2017 10; 76(2):e47-e51. doi: 10.1097/qai.0000000000001455. [PMID: 28542081]
  • M Zitzmann, J Rohayem, J Raidt, S Kliesch, N Kumar, R Sitruk-Ware, E Nieschlag. Impact of various progestins with or without transdermal testosterone on gonadotropin levels for non-invasive hormonal male contraception: a randomized clinical trial. Andrology. 2017 May; 5(3):516-526. doi: 10.1111/andr.12328. [PMID: 28189123]
  • Jiawei He, Qing Wang, Xiangling Ma, Hongqin Yang, Shanshan Li, Kailin Xu, Hui Li. Probing the binding of two 19-nortestosterone derivatives to human serum albumin: insights into the interactions of steroid hormone drugs with functional biomacromolecule. Journal of molecular recognition : JMR. 2016 09; 29(9):415-25. doi: 10.1002/jmr.2540. [PMID: 26940023]
  • Xiangling Ma, Qing Wang, Lili Wang, Yanmei Huang, Xiaoxiang Liao, Hui Li. Investigation on the Interaction of Norgestrel with Human Serum Albumin Using Spectroscopy and Molecular-Docking Method. Journal of biochemical and molecular toxicology. 2016 Jun; 30(6):287-94. doi: 10.1002/jbt.21790. [PMID: 26778492]
  • Gopinath Nallani, Barney Venables, Lisa Constantine, Duane Huggett. Comparison of Measured and Predicted Bioconcentration Estimates of Pharmaceuticals in Fish Plasma and Prediction of Chronic Risk. Bulletin of environmental contamination and toxicology. 2016 May; 96(5):580-4. doi: 10.1007/s00128-016-1782-y. [PMID: 27003806]
  • Magdalena M Piróg, Tomasz Milewicz, Robert Jach, Anetta Undas. Plasma fibrin clot properties in postmenopausal women: effects of hormone therapy. Menopause (New York, N.Y.). 2016 05; 23(5):511-7. doi: 10.1097/gme.0000000000000585. [PMID: 26836244]
  • Mary Abraham, Jennifer Mitchell, Debra Simsovits, James Gasperino. Hypertriglyceridemic Pancreatitis Caused by the Oral Contraceptive Agent Estrostep. Journal of intensive care medicine. 2015 Jul; 30(5):303-7. doi: 10.1177/0885066614528083. [PMID: 24671004]
  • Eli Marcelo Lakryc, Rogério Bonassi Machado, José Maria Soares, César Eduardo Fernandes, Edmund Chada Baracat. What is the influence of hormone therapy on homocysteine and crp levels in postmenopausal women?. Clinics (Sao Paulo, Brazil). 2015 02; 70(2):107-13. doi: 10.6061/clinics/2015(02)07. [PMID: 25789519]
  • Eva Lundström, Peter Conner, Sabine Naessén, Lars Löfgren, Kjell Carlström, Gunnar Söderqvist. Estrone - a partial estradiol antagonist in the normal breast. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 2015; 31(9):747-9. doi: 10.3109/09513590.2015.1062866. [PMID: 26190536]
  • Barent N DuBois, Jessica Atrio, Frank Z Stanczyk, Ganesh Cherala. Increased exposure of norethindrone in HIV+ women treated with ritonavir-boosted atazanavir therapy. Contraception. 2015 Jan; 91(1):71-5. doi: 10.1016/j.contraception.2014.08.009. [PMID: 25245190]
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