Chemical Formula: C20H26O2
Chemical Formula C20H26O2
Found 183 metabolite its formula value is C20H26O2
Norethindrone
A synthetic progestational hormone with actions similar to those of progesterone but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception. [PubChem] CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4789; ORIGINAL_PRECURSOR_SCAN_NO 4788 INTERNAL_ID 429; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9046; ORIGINAL_PRECURSOR_SCAN_NO 9044 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9061; ORIGINAL_PRECURSOR_SCAN_NO 9058 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9106; ORIGINAL_PRECURSOR_SCAN_NO 9102 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9046; ORIGINAL_PRECURSOR_SCAN_NO 9044 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9063; ORIGINAL_PRECURSOR_SCAN_NO 9058 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4892; ORIGINAL_PRECURSOR_SCAN_NO 4890 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4826; ORIGINAL_PRECURSOR_SCAN_NO 4825 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4801; ORIGINAL_PRECURSOR_SCAN_NO 4798 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4810; ORIGINAL_PRECURSOR_SCAN_NO 4809 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9085; ORIGINAL_PRECURSOR_SCAN_NO 9082 CONFIDENCE standard compound; INTERNAL_ID 429; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4809; ORIGINAL_PRECURSOR_SCAN_NO 4806 G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03A - Hormonal contraceptives for systemic use > G03AC - Progestogens G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03D - Progestogens > G03DC - Estren derivatives C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents CONFIDENCE standard compound; INTERNAL_ID 2798 CONFIDENCE standard compound; INTERNAL_ID 4150
Norethynodrel
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents Same as: D05207
Juvocimene 2
Juvocimene 2 is found in herbs and spices. Juvocimene 2 is a constituent of the oil of Ocimum basilicum (sweet basil). Constituent of the oil of Ocimum basilicum (sweet basil). Juvocimene 2 is found in sweet basil and herbs and spices.
4-Oxoretinal
4-Oxoretinal is a predominant retinoids during morphogenesis in mouse skin in vivo. Topical 4-oxoretinal and 4-oxoretinol promoted significant epidermal hyperplasia and metaplasia in mouse tail. They induced a moderate response for epidermal inflammation, compared with retinal, whereas neither 4-oxoretinal nor 4-oxoretinol prevented menadione-induced epidermal lipid peroxidation, unlike retinal and retinol. As analyzed by quantitative PCR, 4-oxoretinal and 4-oxoretinol did not reproduce the significant increased expression of genes coding for keratin 4, amphiregulin, heparin-EGF and CYP26A1, that did induce retinal and retinol. However, both retinal and 4-oxoretinal significantly inhibited the lipopolysaccharide-induced maturation of human dendritic cells in vitro. As analyzed in vivo and in vitro, 4-oxoretinal and 4-oxoretinol were not converted into retinoic acid. We conclude that 4-oxoretinal and 4-oxoretinol exert a moderate direct retinoid-like activity in vivo, thus confirming previous in vitro studies in amphibians showing 4-oxometabolites of vitamin A as bioactive agents rather than inactive catabolites. [HMDB] 4-Oxoretinal is a predominant retinoids during morphogenesis in mouse skin in vivo. Topical 4-oxoretinal and 4-oxoretinol promoted significant epidermal hyperplasia and metaplasia in mouse tail. They induced a moderate response for epidermal inflammation, compared with retinal, whereas neither 4-oxoretinal nor 4-oxoretinol prevented menadione-induced epidermal lipid peroxidation, unlike retinal and retinol. As analyzed by quantitative PCR, 4-oxoretinal and 4-oxoretinol did not reproduce the significant increased expression of genes coding for keratin 4, amphiregulin, heparin-EGF and CYP26A1, that did induce retinal and retinol. However, both retinal and 4-oxoretinal significantly inhibited the lipopolysaccharide-induced maturation of human dendritic cells in vitro. As analyzed in vivo and in vitro, 4-oxoretinal and 4-oxoretinol were not converted into retinoic acid. We conclude that 4-oxoretinal and 4-oxoretinol exert a moderate direct retinoid-like activity in vivo, thus confirming previous in vitro studies in amphibians showing 4-oxometabolites of vitamin A as bioactive agents rather than inactive catabolites.
all-trans-3,4-Didehydroretinoate
This compound belongs to the family of Retinoids. These are compounds that is related to vitamin A, especially retinol. D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
17-Dihydroexemestane
Norethynodrel
Microstegiol
Microstegiol is a natural product found in Salvia lanigera, Salvia microstegia, and other organisms with data available.
(4bS-trans)-4b,5,6,7,8,8a-Hexahydro-4b,8,8-trimethyl-2-(1-methylethyl)-3,9-phenanthrendion|taxodione
abieta-5,8,11,13-tetraene-18-oic acid|centdaroic acid
Podocarpa-1,8,11,13-tetraen-3-one, 12-hydroxy-13-isopropyl-
18-norabieta-3,8,11,13-tetraene-3-oic acid|triptobenzene D
(13(15))-10-Oxo-4,10-seco-2,4,13(15),17-spatatetraen-12-al|(13Z)-10-oxo-4,10-secospata-2,4,13(15),17-tetraen-12-al
8,11,13-cleistanthatrien-3,7-dione|8,11,13-Cleistanthatriene-3,7-dione
3,4,18beta-cyclopropa-ent-abieta-8(14),13(15)-dien-16,12-olide
(+)-(10R*)-cembra-1Z,3Z,7E,11Z,15-pentaen-20,10-olide
15,16-epoxylabda-5,8,13(16),14-tetraen-7-one|leoleorin B
8,9,11,14-didehydrovouacapen-5alpha-ol|8,9,11,14-Tetradehydro-5alpha-5-Vouacapenol
(R)-2-Isopropyl-8,8,8a-trimethyl-6,7,8,8a-tetrahydrophenanthrene-3,4-diol
Norethindrone
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03A - Hormonal contraceptives for systemic use > G03AC - Progestogens G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03D - Progestogens > G03DC - Estren derivatives C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents CONFIDENCE standard compound; INTERNAL_ID 8723
h_253_Methandienone_m3_lt
4-Oxoretinal
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
Benzestrol
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen
(4S)-4α-[(Z)-2-(3-Furyl)vinyl]-4a,5,6,7,8,8aβ-hexahydro-3,4aα,8,8-tetramethylnaphthalen-1(4H)-one
(8S,9S,10R,14S)-13-Ethyl-11-methylene-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione
(8R,9S,10R,13S,14S)-17-hydroxy-10,13,17-trimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
13-Ethyl-3-methoxygona-1,3,5(10),8-tetraen-17beta-ol
3-Hydroxy-1,2-dimethylestra-1,3,5(10)-trien-17-one
4-[2-(4-hydroxy-3,5-dimethylphenyl)butan-2-yl]-2,6-dimethylphenol
Atamestane
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1740 - Aromatase Inhibitor D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist D004791 - Enzyme Inhibitors
Infecundin
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D011372 - Progestins D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
Methestrol
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen
1,2,3,4,4a,5,6,11,12,12a-Decahydro-8-methoxy-12a-methyl-1-chrysenol
17alpha-Ethinyl-19-nortestosterone
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
(13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
(10R,13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
rel-(+)-(10R)-cembra-1E,3E,7E,11Z,15-pentaen-20,10-olide
A cembrane diterpenoid isolated from the leaves of Croton gratissimus.
rel-(+)-(10R)-cembra-1Z,3Z,7E,11Z,15-pentaen-20,10-olide
A cembrane diterpenoid isolated from the leaves of Croton gratissimus.
Triptobenzene D
An abietane diterpenoid with formula C20H26O2, originally isolated from Tripterygium wilfordii.
3-Methoxy-5,10-seco-5,19-cycloandrosta-1(10),2,4-trien-17-one
(8R,9R,13S,14R,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
3,4-Didehydroretinoic acid
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
3-Methoxy-D-homoestra-1,3,5(10),8-tetraen-17abeta-ol
3-Methoxy-5,19-cyclo-5,10-secoandrosta-1(10),2,4-trien-17-one
all-trans-3,4-Didehydroretinoic acid
A retinoid obtained by 3,4-desaturation of beta-ionone ring of all-trans-retinoic acid
all-trans-4-oxoretinal
A retinoid that is all-trans-retinal carrying an oxo substituent at position 4 on the cyclohexenyl ring.
(1s,8z,13r,17r)-4,9,13,17-tetramethyl-6-oxatricyclo[11.4.0.0³,⁷]heptadeca-3(7),4,8,15-tetraen-14-one
(9e)-4,9,13,17-tetramethyl-6-oxatricyclo[11.4.0.0³,⁷]heptadeca-3(7),4,9,15-tetraen-14-one
(4as)-6-hydroxy-7-isopropyl-1,1,4a-trimethyl-3,4-dihydro-2h-phenanthren-9-one
(1s,9e,13r,17r)-4,9,13,17-tetramethyl-6-oxatricyclo[11.4.0.0³,⁷]heptadeca-3(7),4,9,15-tetraen-14-one
2-isopropyl-4b,8,8-trimethyl-5,6,7,8a-tetrahydrophenanthrene-1,4-dione
(4bs)-4-hydroxy-2-isopropyl-4b,8,8-trimethyl-6,7-dihydro-5h-phenanthren-3-one
6-hydroxy-7-isopropyl-1,1,4a-trimethyl-3,4-dihydro-2h-phenanthren-9-one
(1r,2s,5r,7s,8r,17r)-2,7,14-trimethyl-16-oxapentacyclo[9.7.0.0²,⁸.0⁵,⁷.0¹³,¹⁷]octadeca-11,13-dien-15-one
(4bs,8as)-2-isopropyl-4b,8,8-trimethyl-5,6,7,8a-tetrahydrophenanthrene-1,4-dione
(1s,4as)-1,4a-dimethyl-7-(prop-1-en-2-yl)-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
(4ar,11br)-4,4,7,11b-tetramethyl-1h,2h,3h,5h,6h-phenanthro[3,2-b]furan-4a-ol
(4as,10as)-7-hydroxy-8-isopropyl-1,1,4a-trimethyl-10,10a-dihydro-9h-phenanthren-4-one
(4as,10ar)-7-hydroxy-8-isopropyl-1,1,4a-trimethyl-10,10a-dihydro-9h-phenanthren-2-one
(1s,2s,5s,6r,7r,10r)-10-methyl-5-[(2z)-6-methylhepta-2,5-dien-2-yl]-8-oxotricyclo[5.2.1.0²,⁶]dec-3-ene-2-carbaldehyde
6-hydroxy-8-isopropyl-1,1,4a-trimethyl-10,10a-dihydro-9h-phenanthren-2-one
(1s,2s,5r,6s,7r,10s)-10-methyl-5-[(2z)-6-methylhepta-2,5-dien-2-yl]-8-oxotricyclo[5.2.1.0²,⁶]dec-3-ene-2-carbaldehyde
methyl (1s,5r,6s)-4-methyl-5-(3-methylbut-2-en-1-yl)-6-phenylcyclohex-3-ene-1-carboxylate
(4as,10ar)-8-ethyl-1,1,4a,7-tetramethyl-3,4,10,10a-tetrahydrophenanthrene-2,9-dione
8,11,13,15-abietatetraen-19-oicacid
{"Ingredient_id": "HBIN013515","Ingredient_name": "8,11,13,15-abietatetraen-19-oicacid","Alias": "NA","Ingredient_formula": "C20H26O2","Ingredient_Smile": "CC(=C)C1=CC2=C(C=C1)C3(CCCC(C3CC2)(C)C(=O)O)C","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "5","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
