Anastrozole (BioDeep_00000003057)

 

Secondary id: BioDeep_00000398831

human metabolite blood metabolite Chemicals and Drugs Volatile Flavor Compounds


代谢物信息卡片


alpha,alpha,Alpha,alpha-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

化学式: C17H19N5 (293.1640374)
中文名称: 阿那曲唑
谱图信息: 最多检出来源 Viridiplantae(plant) 20%

分子结构信息

SMILES: CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N
InChI: InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3

描述信息

Anastrozole is a drug indicated in the treatment of breast cancer in post-menopausal women. It is used both in adjuvant therapy (i.e. following surgery) and in metastatic breast cancer. It decreases the amount of estrogens that the body makes. Anastrozole belongs in the class of drugs known as aromatase inhibitors. It inhibits the enzyme aromatase, which is responsible for converting androgens (produced by women in the adrenal glands) to estrogens.
CONFIDENCE standard compound; INTERNAL_ID 166; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7616; ORIGINAL_PRECURSOR_SCAN_NO 7613
CONFIDENCE standard compound; INTERNAL_ID 166; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7651; ORIGINAL_PRECURSOR_SCAN_NO 7649
CONFIDENCE standard compound; INTERNAL_ID 166; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7606; ORIGINAL_PRECURSOR_SCAN_NO 7604
CONFIDENCE standard compound; INTERNAL_ID 166; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7609; ORIGINAL_PRECURSOR_SCAN_NO 7607
CONFIDENCE standard compound; INTERNAL_ID 166; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7592; ORIGINAL_PRECURSOR_SCAN_NO 7590
CONFIDENCE standard compound; INTERNAL_ID 166; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7638; ORIGINAL_PRECURSOR_SCAN_NO 7636
L - Antineoplastic and immunomodulating agents > L02 - Endocrine therapy > L02B - Hormone antagonists and related agents > L02BG - Aromatase inhibitors
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D065088 - Steroid Synthesis Inhibitors
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor
D004791 - Enzyme Inhibitors > D065088 - Steroid Synthesis Inhibitors > D047072 - Aromatase Inhibitors
C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1740 - Aromatase Inhibitor
C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist
CONFIDENCE standard compound; INTERNAL_ID 2750
CONFIDENCE standard compound; INTERNAL_ID 8532
D000970 - Antineoplastic Agents

同义名列表

15 个代谢物同义名

alpha,alpha,Alpha,alpha-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile; 2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile; Α,α,alpha,alpha-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile; a,a,Alpha,alpha-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile; 2,2-(5-(1H-1,2,4-Triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile); AstraZeneca brand OF anastrozole; Zeneca brand OF anastrozole; Astra brand OF anastrozole; Zeneca ZD 1033; Anastrazole; Anastrozole; Anastrozol; ICI D1033; Arimidex; Anastrozole



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Osama Alomar, Kehinde S Okunade, Hamed Kord Varkaneh, Ghada Ghourab, Jouri Ahmed Alsourani, Kamar Allayl Alras, Mohd Diya Masmoum, Aya Alfardous Alazm, Ismail A Al-Badawi, Hany Salem, Ahmed Abu-Zaid. The Effect of Anastrozole on the Lipid Profile: Systematic Review and Meta-analysis of Randomized Controlled Trials. Clinical therapeutics. 2022 09; 44(9):1214-1224. doi: 10.1016/j.clinthera.2022.08.003. [PMID: 36031476]
  • Bin Guo, Jiao-Jiao Li, Ya-Ling Ma, Yu-Tao Zhao, Jian-Guo Liu. Efficacy and safety of letrozole or anastrozole in the treatment of male infertility with low testosterone-estradiol ratio: A meta-analysis and systematic review. Andrology. 2022 07; 10(5):894-909. doi: 10.1111/andr.13185. [PMID: 35438843]
  • Ying Wang, Tongtong Wang, Han Fang, Hui Huang, Lijuan Fang, XuanGuo Zhang. Evaluation of Pharmacokinetics and Safety With Bioequivalence of Anastrozole in Healthy Chinese Volunteers: Bioequivalence Study Findings. Clinical pharmacology in drug development. 2022 06; 11(6):687-694. doi: 10.1002/cpdd.1099. [PMID: 35485182]
  • Bjørn-Erik Bertelsen, Kristin Viste, Thomas Helland, Magnus Hagland, Håvard Søiland, Jürgen Geisler, Tone Hoel Lende, Per Eystein Lønning, Jørn V Sagen, Gunnar Mellgren, Bjørg Almås. Simultaneous Quantification of Aromatase Inhibitors and Estrogens in Postmenopausal Breast Cancer Patients. The Journal of clinical endocrinology and metabolism. 2022 04; 107(5):1368-1374. doi: 10.1210/clinem/dgab923. [PMID: 34958096]
  • Dilshad Ahmad, Faisal A Al Meshaiti, Yazeed K Al Anazi, Osama Al Owassil, Alaa Eldeen B Yassin. Rapid and Sensitive Liquid Chromatographic Method for Determination of Anastrozole in Different Polymer-Lipid Hybrid Nanoparticles. SLAS technology. 2021 08; 26(4):384-391. doi: 10.1177/2472630320982308. [PMID: 33435790]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Koji Shiraishi, Shintaro Oka, Hideyasu Matsuyama. Testicular Testosterone and Estradiol Concentrations and Aromatase Expression in Men with Nonobstructive Azoospermia. The Journal of clinical endocrinology and metabolism. 2021 03; 106(4):e1803-e1815. doi: 10.1210/clinem/dgaa860. [PMID: 33236081]
  • Alyssa Streff, Michele Chu-Pilli, Alison Stopeck, Pavani Chalasani. Changes in serum estradiol levels with Estring in postmenopausal women with breast cancer treated with aromatase inhibitors. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2021 Jan; 29(1):187-191. doi: 10.1007/s00520-020-05466-1. [PMID: 32328775]
  • Ashish Kumar, Ajit Singh, S J S Flora, Rahul Shukla. Box-Behnken Design Optimized TPGS Coated Bovine Serum Albumin Nanoparticles Loaded with Anastrozole. Current drug delivery. 2021; 18(8):1136-1147. doi: 10.2174/1567201818666210202104810. [PMID: 33530907]
  • Ying Wang, Yu An, Weiwei Ma, Huiyan Yu, Yanhui Lu, Xiaona Zhang, Yushan Wang, Wen Liu, Tao Wang, Rong Xiao. 27-Hydroxycholesterol contributes to cognitive deficits in APP/PS1 transgenic mice through microbiota dysbiosis and intestinal barrier dysfunction. Journal of neuroinflammation. 2020 Jun; 17(1):199. doi: 10.1186/s12974-020-01873-7. [PMID: 32593306]
  • Mohit Butaney, Nannan Thirumavalavan, Adithya Balasubramanian, J Abram McBride, Jabez Gondokusumo, Alexander W Pastuszak, Larry I Lipshultz. Treatment of Estrogen Levels in the Management of Hypogonadism: An Anonymous Survey of ISSM Members. Urology. 2020 05; 139(?):104-109. doi: 10.1016/j.urology.2020.01.032. [PMID: 32045591]
  • Tao He, Wenhao Yang, Xinyi Zhang, Ping Li, Dandan Yang, Yunhao Wu, Yuan Fan, Mengya Xiang, Qianqian Huang, Jing Chen, Runke Zhou, Qing Lv, Jie Chen. Comparative effectiveness of tamoxifen, toremifene, letrozole, anastrozole, and exemestane on lipid profiles in breast cancer patients: A network meta-analysis. Medicine. 2020 Jan; 99(2):e18550. doi: 10.1097/md.0000000000018550. [PMID: 31914031]
  • Min Wei, Yu-Rong Xu, Kui Liu, Peng Wen. Anastrozole-induced pulmonary cryptococcosis in a patient with early breast cancer: A case report. Medicine. 2020 Jan; 99(2):e18688. doi: 10.1097/md.0000000000018688. [PMID: 31914067]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Rebecca L Glaser, Anne E York. Subcutaneous Testosterone Anastrozole Therapy in Men: Rationale, Dosing, and Levels on Therapy. International journal of pharmaceutical compounding. 2019 Jul; 23(4):325-339. doi: NULL. [PMID: 31315085]
  • Rüdiger Nave, Uwe Mellinger, Stefan Klein, Joachim Höchel, Heinz Schmitz. Absence of Drug-Drug Interaction of Anastrozole on Levonorgestrel Delivered Simultaneously by an Intravaginal Ring: Results of a Phase 2 Trial. Journal of clinical pharmacology. 2019 07; 59(7):1022-1028. doi: 10.1002/jcph.1396. [PMID: 30791125]
  • Tanda M Dudenkov, Duan Liu, Junmei Cairns, Sandhya Devarajan, Yongxian Zhuang, James N Ingle, Aman U Buzdar, Mark E Robson, Michiaki Kubo, Anthony Batzler, Poulami Barman, Gregory D Jenkins, Erin E Carlson, Matthew P Goetz, Donald W Northfelt, Alvaro Moreno-Aspitia, Zeruesenay Desta, Joel M Reid, Krishna R Kalari, Liewei Wang, Richard M Weinshilboum. Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2. Clinical pharmacology and therapeutics. 2019 07; 106(1):219-227. doi: 10.1002/cpt.1359. [PMID: 30648747]
  • Kirsty M Mair, Katie Y Harvey, Alasdair D Henry, Dianne Z Hillyard, Margaret Nilsen, Margaret R MacLean. Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension. The European respiratory journal. 2019 06; 53(6):. doi: 10.1183/13993003.01524-2018. [PMID: 30923189]
  • Ved Bhushan Arya, Justin H Davies. Idiopathic gonadotropin-independent precocious puberty - is regular surveillance required?. Journal of pediatric endocrinology & metabolism : JPEM. 2019 Apr; 32(4):403-407. doi: 10.1515/jpem-2018-0419. [PMID: 30849047]
  • Liangyu Xia, Shunchen Qiu, Zhenqi Liu, Meiying Ning. Preparation and in vitro/in vivo evaluation of anastrozole reservoir-type intravaginal ring. Biomedical chromatography : BMC. 2019 Apr; 33(4):e4459. doi: 10.1002/bmc.4459. [PMID: 30536439]
  • Katherine N Bachmann, Shi Huang, Hang Lee, Laura E Dichtel, Deepak K Gupta, John C Burnett, Karen K Miller, Thomas J Wang, Joel S Finkelstein. Effect of Testosterone on Natriuretic Peptide Levels. Journal of the American College of Cardiology. 2019 03; 73(11):1288-1296. doi: 10.1016/j.jacc.2018.12.062. [PMID: 30898204]
  • Stefanie L Groenland, Merel van Nuland, Remy B Verheijen, Jan H M Schellens, Jos H Beijnen, Alwin D R Huitema, Neeltje Steeghs. Therapeutic Drug Monitoring of Oral Anti-Hormonal Drugs in Oncology. Clinical pharmacokinetics. 2019 03; 58(3):299-308. doi: 10.1007/s40262-018-0683-0. [PMID: 29862467]
  • M van Nuland, N Venekamp, N de Vries, K A M de Jong, H Rosing, J H Beijnen. Development and validation of an UPLC-MS/MS method for the therapeutic drug monitoring of oral anti-hormonal drugs in oncology. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2019 Feb; 1106-1107(?):26-34. doi: 10.1016/j.jchromb.2019.01.001. [PMID: 30639947]
  • Aideen M Campbell, Melanie Morris, Rebecca Gallagher, Ruth Boyd, Hazel Carson, D Paul Harkin, Ewa Wielogorska, Christopher Elliott, Kienan I Savage, Stuart A McIntosh. Chemoprevention in BRCA1 mutation carriers (CIBRAC): protocol for an open allocation crossover feasibility trial assessing mechanisms of chemoprevention with goserelin and anastrozole versus tamoxifen and acceptability of treatment. BMJ open. 2018 12; 8(12):e023115. doi: 10.1136/bmjopen-2018-023115. [PMID: 30580266]
  • Yuzhu Zhang, Jingjing Wu, Yue Zhou, Yulian Yin, Hongfeng Chen. Effects of psoralen on the pharmacokinetics of anastrozole in rats. Pharmaceutical biology. 2018 Dec; 56(1):433-439. doi: 10.1080/13880209.2018.1501584. [PMID: 30345900]
  • Keisei Anan, Shoshu Mitsuyama, Yasuhiro Yanagita, Morihiko Kimura, Hiroyoshi Doihara, Kansei Komaki, Mikihiro Kusama, Tadashi Ikeda. [Follicle-Stimulating Hormone and Estradiol Levels in Japanese Women Treated with Toremifene and Anastrozole for Two Years - A Retrospective Analysis of Data from a Prospective Randomized Trial]. Gan to kagaku ryoho. Cancer & chemotherapy. 2018 Dec; 45(12):1725-1728. doi: . [PMID: 30587728]
  • Amany Abdel-Rahman Mohamed, Mona M Ahmed, Mohamed Gomaa, Lamiaa L M Ebraheim. Bone health consequence of adjuvant Anastrozole in monotherapy or associated with biochanin-A in ovariectomized rat model. Life sciences. 2018 Nov; 212(?):159-167. doi: 10.1016/j.lfs.2018.09.059. [PMID: 30290186]
  • Wei Tian, Miaowei Wu, Yongchuan Deng. Comparison of Changes in the Lipid Profiles of Eastern Chinese Postmenopausal Women With Early-Stage Breast Cancer Treated With Different Aromatase Inhibitors: A Retrospective Study. Clinical pharmacology in drug development. 2018 11; 7(8):837-843. doi: 10.1002/cpdd.420. [PMID: 29287126]
  • Xu Liang, Adrien Briaux, Véronique Becette, Camille Benoist, Anais Boulai, Walid Chemlali, Anne Schnitzler, Sylvain Baulande, Sofia Rivera, Marie-Ange Mouret-Reynier, Laurence Venat Bouvet, Thibaut De La Motte Rouge, Jérôme Lemonnier, Florence Lerebours, Céline Callens. Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609). Journal of hematology & oncology. 2018 10; 11(1):124. doi: 10.1186/s13045-018-0670-9. [PMID: 30305115]
  • Azza A A Galal, Amany Abdel-Rahman Mohamed, Safaa I Khater, Mohamed M M Metwally. Beneficial role of biochanin A on cutaneous and renal tissues of ovariectomized rats treated with anastrozole. Life sciences. 2018 May; 201(?):9-16. doi: 10.1016/j.lfs.2018.03.037. [PMID: 29567078]
  • Xiaoyang Sun, Mingming Lv, Binjie Wang, Simin Zhao, Ping Guo, Shixiao Wang, Liqiang Gu, Xiaohui Chen. Comparative pharmacokinetics study of anastrozole after single administration and combination with celecoxib. Xenobiotica; the fate of foreign compounds in biological systems. 2018 Mar; 48(3):279-284. doi: 10.1080/00498254.2017.1298872. [PMID: 28906164]
  • Nasimeh Yazdani, Stacy Matthews Branch. Daily subcutaneous testosterone for management of testosterone deficiency. Frontiers in bioscience (Elite edition). 2018 03; 10(2):334-343. doi: 10.2741/e825. [PMID: 29293461]
  • Polly Niravath, Bingshu Chen, Judy-Anne W Chapman, Sandeep K Agarwal, Robert L Welschhans, Tim Bongartz, Krishna R Kalari, Lois E Shepherd, John Bartlett, Kathleen Pritchard, Karen Gelmon, Susan G Hilsenbeck, Mothaffar F Rimawi, C Kent Osborne, Paul E Goss, James N Ingle. Vitamin D Levels, Vitamin D Receptor Polymorphisms, and Inflammatory Cytokines in Aromatase Inhibitor-Induced Arthralgias: An Analysis of CCTG MA.27. Clinical breast cancer. 2018 02; 18(1):78-87. doi: 10.1016/j.clbc.2017.10.009. [PMID: 29128193]
  • Giovanna Di Nardo, Giuseppe Cimicata, Roberta Baravalle, Valentina Dell'Angelo, Alberto Ciaramella, Gianluca Catucci, Piero Ugliengo, Gianfranco Gilardi. Working at the membrane interface: Ligand-induced changes in dynamic conformation and oligomeric structure in human aromatase. Biotechnology and applied biochemistry. 2018 Jan; 65(1):46-53. doi: 10.1002/bab.1613. [PMID: 28926141]
  • Rüdiger Nave, Stefan Klein, André Müller, Xinying Chang, Joachim Höchel. Absence of Effect of Intravaginal Miconazole, Clindamycin, Nonoxynol-9, and Tampons on the Pharmacokinetics of an Anastrozole/Levonorgestrel Intravaginal Ring. Journal of clinical pharmacology. 2018 Jan; 58(1):97-106. doi: 10.1002/jcph.984. [PMID: 28783867]
  • Yusra A Alyafee, Manal Alaamery, Shahad Bawazeer, Mansour S Almutairi, Badr Alghamdi, Nawaf Alomran, Atia Sheereen, Maha Daghestani, Salam Massadeh. Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines. International journal of nanomedicine. 2018; 13(?):199-208. doi: 10.2147/ijn.s151139. [PMID: 29343958]
  • Ralf Regenthal, Margarita Voskanian, Frank Baumann, Jens Teichert, Christian Brätter, Achim Aigner, Getu Abraham. Pharmacokinetic evaluation of a transdermal anastrozole-in-adhesive formulation. Drug design, development and therapy. 2018; 12(?):3653-3664. doi: 10.2147/dddt.s170764. [PMID: 30464397]
  • M B Abubakar, S H Gan. Correlation of Serum Estradiol and Duration of Anastrazole Therapy with Treatment Related Adverse Effects Among Postmenopausal Breast Cancer Women: A Cross-sectional Study. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. 2017 Dec; 32(2):219-225. doi: NULL. [PMID: 29485645]
  • Irene E G van Hellemond, Ingeborg J H Vriens, Petronella G M Peer, Astrid C P Swinkels, Carolien H Smorenburg, Caroline M Seynaeve, Maurice J C van der Sangen, Judith R Kroep, Hiltje de Graaf, Aafke H Honkoop, Frans L G Erdkamp, Franchette W P J van den Berkmortel, Jos J E M Kitzen, Maaike de Boer, Wïlfred K de Roos, Sabine C Linn, Alexander L T Imholz, Vivianne C G Tjan-Heijnen. Ovarian Function Recovery During Anastrozole in Breast Cancer Patients With Chemotherapy-Induced Ovarian Function Failure. Journal of the National Cancer Institute. 2017 12; 109(12):. doi: 10.1093/jnci/djx074. [PMID: 29546343]
  • Hiroyuki Kusuhara, Tadayuki Takashima, Hisako Fujii, Tsutomu Takashima, Masaaki Tanaka, Akira Ishii, Shusaku Tazawa, Kazuhiro Takahashi, Kayo Takahashi, Hidekichi Tokai, Tsuneo Yano, Makoto Kataoka, Akihiro Inano, Suguru Yoshida, Takamitsu Hosoya, Yuichi Sugiyama, Shinji Yamashita, Taisuke Hojo, Yasuyoshi Watanabe. Comparison of pharmacokinetics of newly discovered aromatase inhibitors by a cassette microdosing approach in healthy Japanese subjects. Drug metabolism and pharmacokinetics. 2017 Dec; 32(6):293-300. doi: 10.1016/j.dmpk.2017.09.003. [PMID: 29137842]
  • Ellen Werber Leschek, Armando C Flor, Joy C Bryant, Janet V Jones, Kevin M Barnes, Gordon B Cutler. Effect of Antiandrogen, Aromatase Inhibitor, and Gonadotropin-releasing Hormone Analog on Adult Height in Familial Male Precocious Puberty. The Journal of pediatrics. 2017 11; 190(?):229-235. doi: 10.1016/j.jpeds.2017.07.047. [PMID: 29144249]
  • Namki Hong, Han Gyul Yoon, Da Hea Seo, Seho Park, Seung Il Kim, Joo Hyuk Sohn, Yumie Rhee. Different patterns in the risk of newly developed fatty liver and lipid changes with tamoxifen versus aromatase inhibitors in postmenopausal women with early breast cancer: A propensity score-matched cohort study. European journal of cancer (Oxford, England : 1990). 2017 09; 82(?):103-114. doi: 10.1016/j.ejca.2017.05.002. [PMID: 28651157]
  • Oleksandra Klapko, Elie Ghoulam, Shriram Jakate, Sheila Eswaran, Lydia Usha. Anastrozole-induced Autoimmune Hepatitis: A Rare Complication of Breast Cancer Therapy. Anticancer research. 2017 08; 37(8):4173-4176. doi: 10.21873/anticanres.11805. [PMID: 28739702]
  • Lee S Schwartzberg, Denise A Yardley, Anthony D Elias, Manish Patel, Patricia LoRusso, Howard A Burris, Ayca Gucalp, Amy C Peterson, Martha E Blaney, Joyce L Steinberg, Jacqueline A Gibbons, Tiffany A Traina. A Phase I/Ib Study of Enzalutamide Alone and in Combination with Endocrine Therapies in Women with Advanced Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Aug; 23(15):4046-4054. doi: 10.1158/1078-0432.ccr-16-2339. [PMID: 28280092]
  • Xinping Chen, Eric D Austin, Megha Talati, Joshua P Fessel, Eric H Farber-Eger, Evan L Brittain, Anna R Hemnes, James E Loyd, James West. Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects. The European respiratory journal. 2017 08; 50(2):. doi: 10.1183/13993003.02337-2016. [PMID: 28775043]
  • A Oberguggenberger, V Meraner, M Sztankay, B Beer, G Weigel, H Oberacher, G Kemmler, T Czech, B Holzner, L Wildt, B Sperner-Unterweger, M Daniaux, M Hubalek. Can we use gonadotropin plasma concentration as surrogate marker for BMI-related incomplete estrogen suppression in breast cancer patients receiving anastrozole?. BMC cancer. 2017 03; 17(1):226. doi: 10.1186/s12885-017-3208-6. [PMID: 28351392]
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