Dibenz(a,h)acridine (BioDeep_00000003045)

   


代谢物信息卡片


Dibenz(a,h)acridine

化学式: C21H13N (279.1048)
中文名称: 二苯并(A,H)吖啶
谱图信息: 最多检出来源 Viridiplantae(plant) 10.53%

分子结构信息

SMILES: C1=CC=C2C(=C1)C=CC3=C2C=C4C=CC5=CC=CC=C5C4=N3
InChI: InChI=1S/C21H13N/c1-3-7-17-14(5-1)11-12-20-19(17)13-16-10-9-15-6-2-4-8-18(15)21(16)22-20/h1-13H

描述信息

D009676 - Noxae > D002273 - Carcinogens
CONFIDENCE standard compound; INTERNAL_ID 8267

同义名列表

3 个代谢物同义名

Dibenz(a,h)acridine; Dibenz[a,h]acridine; Dibenz[a,h]acridine



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AHR, ARRB1, CDH1, CTNNB1, HSP90AA1, HSPA8, PPP2CA, RAC1, TP53
Peripheral membrane protein 1 HSPA8
Endoplasmic reticulum membrane 3 NRAS, RAC1, SLC27A5
Nucleus 10 ACR, AHR, ARRB1, CDH1, CTNNB1, HSP90AA1, HSPA8, PPP2CA, RAC1, TP53
autophagosome 1 HSPA8
cytosol 11 ABR, AHR, ARRB1, CDH1, CTNNB1, HSP90AA1, HSPA8, NRAS, PPP2CA, RAC1, TP53
dendrite 1 RAC1
nuclear body 1 ARRB1
trans-Golgi network 2 CDH1, RAC1
centrosome 2 CTNNB1, TP53
nucleoplasm 7 AHR, ARRB1, CDH1, CTNNB1, HSP90AA1, HSPA8, TP53
Cell membrane 7 ARRB1, CDH1, CTNNB1, HSP90AA1, NRAS, RAC1, SLC27A5
Lipid-anchor 2 NRAS, RAC1
Cytoplasmic side 3 HSPA8, NRAS, RAC1
lamellipodium 3 CDH1, CTNNB1, RAC1
ruffle membrane 1 RAC1
Cell projection, axon 1 ABR
Multi-pass membrane protein 2 SLC27A5, SLC45A2
Golgi apparatus membrane 1 NRAS
Synapse 4 ABR, CTNNB1, PPP2CA, RAC1
cell cortex 2 CTNNB1, RAC1
cell junction 2 CDH1, CTNNB1
cell surface 2 HSP90AA1, HSPA8
dendritic shaft 1 HSPA8
glutamatergic synapse 5 ABR, CDH1, CTNNB1, HSPA8, RAC1
Golgi apparatus 2 CDH1, NRAS
Golgi membrane 2 ARRB1, NRAS
lysosomal membrane 2 ARRB1, HSPA8
neuronal cell body 1 HSP90AA1
postsynapse 2 CDH1, RAC1
presynaptic membrane 1 CTNNB1
synaptic vesicle 1 HSPA8
endosome 1 CDH1
plasma membrane 9 ARRB1, CDH1, CTNNB1, HSP90AA1, HSPA8, NRAS, PPP2CA, RAC1, SLC27A5
terminal bouton 1 HSPA8
Membrane 10 ABR, CDH1, CTNNB1, HSP90AA1, HSPA8, NRAS, PPP2CA, RAC1, SLC45A2, TP53
apical plasma membrane 1 HSP90AA1
axon 1 ABR
basolateral plasma membrane 2 CTNNB1, HSP90AA1
extracellular exosome 7 CDH1, CTNNB1, HSP90AA1, HSPA8, NRAS, PPP2CA, RAC1
Lysosome membrane 1 HSPA8
endoplasmic reticulum 2 SLC27A5, TP53
extracellular space 1 HSPA8
lysosomal lumen 2 HSP90AA1, HSPA8
perinuclear region of cytoplasm 4 CDH1, CTNNB1, HSP90AA1, HSPA8
Schaffer collateral - CA1 synapse 2 ABR, CTNNB1
adherens junction 2 CDH1, CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
mitochondrion 3 HSP90AA1, PPP2CA, TP53
protein-containing complex 6 ACR, AHR, CTNNB1, HSP90AA1, SLC27A5, TP53
postsynaptic density 1 HSPA8
Single-pass type I membrane protein 1 CDH1
Secreted 1 RAC1
extracellular region 5 ACR, CDH1, HSP90AA1, HSPA8, RAC1
cytoplasmic side of plasma membrane 1 CDH1
Mitochondrion matrix 1 TP53
mitochondrial matrix 1 TP53
transcription regulator complex 3 AHR, CTNNB1, TP53
photoreceptor inner segment 1 HSPA8
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
nuclear membrane 1 CDH1
actin cytoskeleton 1 CDH1
dendritic spine 3 ABR, HSPA8, RAC1
perikaryon 1 HSPA8
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
cytoplasmic vesicle 2 ARRB1, RAC1
microtubule cytoskeleton 1 PPP2CA
nucleolus 2 HSPA8, TP53
Wnt signalosome 1 CTNNB1
Melanosome membrane 1 SLC45A2
Membrane, clathrin-coated pit 1 ARRB1
apical part of cell 1 CTNNB1
cell-cell junction 1 CTNNB1
clathrin-coated pit 1 ARRB1
Golgi-associated vesicle 1 ACR
postsynaptic membrane 1 CTNNB1
Cell projection, lamellipodium 1 RAC1
Membrane raft 1 PPP2CA
Cytoplasm, cytoskeleton 2 CTNNB1, TP53
focal adhesion 3 CTNNB1, HSPA8, RAC1
microtubule 1 HSPA8
Cell junction, adherens junction 2 CDH1, CTNNB1
flotillin complex 2 CDH1, CTNNB1
Cell projection, dendritic spine 1 ABR
Nucleus, PML body 1 TP53
PML body 1 TP53
collagen-containing extracellular matrix 1 HSP90AA1
fascia adherens 1 CTNNB1
intermediate filament 1 HSPA8
lateral plasma membrane 2 CDH1, CTNNB1
Late endosome 1 HSPA8
chromatin 3 AHR, ARRB1, TP53
axonal growth cone 1 HSP90AA1
cell periphery 1 CTNNB1
cytoskeleton 1 RAC1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
cytoplasmic ribonucleoprotein granule 1 RAC1
brush border membrane 1 HSP90AA1
Golgi apparatus, trans-Golgi network 1 CDH1
Nucleus, nucleolus 1 HSPA8
spindle pole 2 CTNNB1, PPP2CA
blood microparticle 1 HSPA8
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
spliceosomal complex 1 HSPA8
site of double-strand break 1 TP53
Cytoplasm, cytoskeleton, spindle pole 1 PPP2CA
Recycling endosome membrane 1 RAC1
Endomembrane system 1 CTNNB1
Chromosome, centromere 1 PPP2CA
aryl hydrocarbon receptor complex 1 AHR
Cytoplasmic vesicle membrane 1 ARRB1
Cell projection, dendrite 1 RAC1
tertiary granule membrane 1 NRAS
Melanosome 3 HSP90AA1, HSPA8, RAC1
euchromatin 1 CTNNB1
germ cell nucleus 1 TP53
replication fork 1 TP53
dendritic growth cone 1 HSP90AA1
myelin sheath 1 HSP90AA1
sperm mitochondrial sheath 1 HSP90AA1
sperm plasma membrane 1 HSP90AA1
pseudopodium 1 ARRB1
basal plasma membrane 1 SLC27A5
Microsome 1 SLC27A5
ficolin-1-rich granule lumen 2 HSP90AA1, HSPA8
secretory granule lumen 2 HSP90AA1, HSPA8
secretory granule membrane 1 RAC1
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
endocytic vesicle membrane 1 ARRB1
FAR/SIN/STRIPAK complex 1 PPP2CA
beta-catenin-TCF complex 1 CTNNB1
anaphase-promoting complex 1 CDH1
chromosome, centromeric region 1 PPP2CA
presynaptic active zone cytoplasmic component 1 CTNNB1
ribonucleoprotein complex 1 HSPA8
[Isoform 2]: Nucleus 1 CDH1
[Isoform 1]: Nucleus 1 TP53
protein folding chaperone complex 1 HSPA8
protein-DNA complex 1 CTNNB1
ficolin-1-rich granule membrane 1 RAC1
postsynaptic specialization membrane 1 HSPA8
apical junction complex 1 CDH1
Prp19 complex 1 HSPA8
Cell junction, desmosome 1 CDH1
desmosome 1 CDH1
Cell projection, pseudopodium 1 ARRB1
catenin complex 2 CDH1, CTNNB1
endocytic vesicle lumen 1 HSP90AA1
NADPH oxidase complex 1 RAC1
glycinergic synapse 1 HSPA8
acrosomal matrix 1 ACR
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane 1 HSPA8
lumenal side of lysosomal membrane 1 HSPA8
lysosomal matrix 1 HSPA8
photoreceptor ribbon synapse 1 HSPA8
beta-catenin-TCF7L2 complex 1 CTNNB1
protein serine/threonine phosphatase complex 1 PPP2CA
nuclear aryl hydrocarbon receptor complex 1 AHR
protein phosphatase type 2A complex 1 PPP2CA
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
cytosolic aryl hydrocarbon receptor complex 1 AHR


文献列表

  • Arkadiusz Szterk, Marek Roszko, Adam Cybulski. Determination of azaarenes in oils using the LC-APCI-MS/MS technique: new environmental toxicant in food oils. Journal of separation science. 2012 Nov; 35(21):2858-65. doi: 10.1002/jssc.201200570. [PMID: 23047737]
  • D H Li, D C Xu, K Randerath. Species and tissue specificities of I-compounds as contrasted with carcinogen adducts in liver, kidney and skin DNA of Sprague-Dawley rats, ICR mice and Syrian hamsters. Carcinogenesis. 1990 Dec; 11(12):2227-32. doi: 10.1093/carcin/11.12.2227. [PMID: 2124953]
  • H K Robinson, C C Duke, G M Holder, A J Ryan. The metabolism of the carcinogen dibenz[a,j]acridine in isolated rat hepatocytes and in vivo in rats. Xenobiotica; the fate of foreign compounds in biological systems. 1990 May; 20(5):457-70. doi: 10.3109/00498259009046861. [PMID: 2349805]