Glycolic acid (BioDeep_00000002845)
Secondary id: BioDeep_00000405201
natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite
代谢物信息卡片
Glycolic acid, monopotassium salt
化学式: C2H4O3 (76.0160434)
中文名称: 乙醇酸, 乙醇酸, 乙醇酸, 羟基乙酸
谱图信息:
最多检出来源 Homo sapiens(blood) 0.73%
Reviewed
Last reviewed on 2024-09-14.
Cite this Page
Glycolic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/glycolic_acid (retrieved
2024-09-17) (BioDeep RN: BioDeep_00000002845). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: C(C(=O)O)O
InChI: InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
描述信息
Glycolic acid (or hydroxyacetic acid) is the smallest alpha-hydroxy acid (AHA). This colourless, odourless, and hygroscopic crystalline solid is highly soluble in water. Due to its excellent capability to penetrate skin, glycolic acid is often used in skin care products, most often as a chemical peel. It may reduce wrinkles, acne scarring, and hyperpigmentation and improve many other skin conditions, including actinic keratosis, hyperkeratosis, and seborrheic keratosis. Once applied, glycolic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together. This allows the outer skin to dissolve, revealing the underlying skin. It is thought that this is due to the reduction of calcium ion concentrations in the epidermis and the removal of calcium ions from cell adhesions, leading to desquamation. Glycolic acid is a known inhibitor of tyrosinase. This can suppress melanin formation and lead to a lightening of skin colour. Acute doses of glycolic acid on skin or eyes leads to local effects that are typical of a strong acid (e.g. dermal and eye irritation). Glycolate is a nephrotoxin if consumed orally. A nephrotoxin is a compound that causes damage to the kidney and kidney tissues. Glycolic acids renal toxicity is due to its metabolism to oxalic acid. Glycolic and oxalic acid, along with excess lactic acid, are responsible for the anion gap metabolic acidosis. Oxalic acid readily precipitates with calcium to form insoluble calcium oxalate crystals. Renal tissue injury is caused by widespread deposition of oxalate crystals and the toxic effects of glycolic acid. Glycolic acid does exhibit some inhalation toxicity and can cause respiratory, thymus, and liver damage if present in very high levels over long periods of time. Elevated glycolic acid without elevated oxalic acid is most likely a result of GI yeast overgrowth (Aspergillus, Penicillium, probably Candida) or due to dietary sources containing glycerol (glycerine). (http://drweyrich.weyrich.com/labs/oat.html). Glycolic acid has also been found to be a metabolite in Acetobacter, Acidithiobacillus, Alcaligenes, Corynebacterium, Cryptococcus, Escherichia, Gluconobacter, Kluyveromyces, Leptospirillum, Pichia, Rhodococcus, Rhodotorula and Saccharomyces (PMID: 11758919; PMID: 26360870; PMID: 14390024).
D003879 - Dermatologic Agents > D007641 - Keratolytic Agents
Found in sugar cane (Saccharum officinarum)
KEIO_ID G012
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
同义名列表
36 个代谢物同义名
Glycolic acid, monopotassium salt; Glycolic acid, monoammonium salt; Glycolic acid, monolithium salt; Glycolic acid, 2-(14)C-labeled; Glycolic acid, monosodium salt; Glycolic acid, 1-(14)C-labeled; Glycolic acid, potassium salt; Glycolic acid, calcium salt; α-Hydroxyacetic acid; alpha-Hydroxyacetic acid; 2-Hydroxyethanoic acid; α-Hydroxyacetate; Hydroxyethanoic acid; 2-Hydroxyacetic acid; Α-hydroxyacetic acid; alpha-Hydroxyacetate; a-Hydroxyacetic acid; Hydroxy-acetic acid; Potassium glycolate; Hydroxyacetic acid; 2-Hydroxyethanoate; Hydroxyethanoate; 2-Hydroxyacetate; Α-hydroxyacetate; Sodium glycolate; a-Hydroxyacetate; Glycollic acid; Hydroxyacetate; glycolic acid; Glycollate; GlyPure 70; HOCH2COOH; Glycocide; Glycolate; GlyPure; Glycolic acid
数据库引用编号
25 个数据库交叉引用编号
- ChEBI: CHEBI:17497
- KEGG: C00160
- KEGGdrug: D78078
- PubChem: 757
- HMDB: HMDB0000115
- Metlin: METLIN3219
- DrugBank: DB03085
- ChEMBL: CHEMBL252557
- Wikipedia: Glycolic_acid
- MetaCyc: GLYCOLLATE
- KNApSAcK: C00007461
- foodb: FDB003298
- chemspider: 737
- CAS: 79-14-1
- MoNA: KO000832
- MoNA: KO000833
- MoNA: KO000834
- MoNA: PS023607
- PMhub: MS000006654
- PubChem: 3460
- PDB-CCD: GOA
- 3DMET: B01175
- NIKKAJI: J1.494J
- RefMet: Glycolic acid
- medchemexpress: HY-W015967
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
145 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- fatty acid ω-oxidation:
O2 + a ω-hydroxy fatty acid ⟶ an ω-oxo fatty acid + hydrogen peroxide
WikiPathways(0)
Plant Reactome(144)
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - PCO cycle:
Gly + NAD + THF ⟶ 5,10-methylene-THF + NADH + ammonia + carbon dioxide
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ajay S Kumar, D Prema, R Gagana Rao, J Prakash, P Balashanmugam, T Devasena, G Devanand Venkatasubbu. Fabrication of poly (lactic-co-glycolic acid)/gelatin electro spun nanofiber patch containing CaCO3/SiO2 nanocomposite and quercetin for accelerated diabetic wound healing.
International journal of biological macromolecules.
2024 Jan; 254(Pt 3):128060. doi:
10.1016/j.ijbiomac.2023.128060. [PMID: 37963500] - Yuanyuan Li, Chaojie Wang, Xile Deng, Runze Cai, Lidong Cao, Chong Cao, Li Zheng, Pengyue Zhao, Qiliang Huang. Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings.
International journal of molecular sciences.
2023 Jun; 24(12):. doi:
10.3390/ijms241210121. [PMID: 37373269] - Asghar Narmani, Roghayyeh Jahedi, Ehsan Bakhshian-Dehkordi, Saeid Ganji, Mahnaz Nemati, Ruhollah Ghahramani-Asl, Kave Moloudi, Seyed Mohammad Hosseini, Hamed Bagheri, Prashant Kesharwani, Ali Khani, Bagher Farhood, Amirhossein Sahebkar. Biomedical applications of PLGA nanoparticles in nanomedicine: Advances in drug delivery systems and cancer therapy.
Expert opinion on drug delivery.
2023 Jun; ?(?):. doi:
10.1080/17425247.2023.2223941. [PMID: 37294853] - Xiangyu Zhang, Santosh Kumar Misra, Parikshit Moitra, Xiuli Zhang, Se-Jin Jeong, Jeremiah Stitham, Astrid Rodriguez-Velez, Arick Park, Yu-Sheng Yeh, William E Gillanders, Daping Fan, Abhinav Diwan, Jaehyung Cho, Slava Epelman, Irfan J Lodhi, Dipanjan Pan, Babak Razani. Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis.
Autophagy.
2023 Mar; 19(3):886-903. doi:
10.1080/15548627.2022.2108252. [PMID: 35982578] - Yue Na, Ning Zhang, Xinyu Zhong, Jinlian Gu, Chang Yan, Shun Yin, Xia Lei, Jihui Zhao, Fang Geng. Polylactic-co-glycolic acid-based nanoparticles modified with peptides and other linkers cross the blood-brain barrier for targeted drug delivery.
Nanomedicine (London, England).
2023 01; 18(2):125-143. doi:
10.2217/nnm-2022-0287. [PMID: 36916394] - Jing Wei, Qianghua Quan, Peiyu Wang, Yiming Wang, Tong Huo, Quan An. Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling.
Cutaneous and ocular toxicology.
2022 Sep; 41(3):257-263. doi:
10.1080/15569527.2022.2109658. [PMID: 35920724] - Maomao Tang, Yuzhe Huang, Xiao Liang, Yaotian Tao, Ning He, Zhenbao Li, Jian Guo, Shuangying Gui. Sorafenib-Loaded PLGA-TPGS Nanosystems Enhance Hepatocellular Carcinoma Therapy Through Reversing P-Glycoprotein-Mediated Multidrug Resistance.
AAPS PharmSciTech.
2022 Apr; 23(5):130. doi:
10.1208/s12249-022-02214-y. [PMID: 35487999] - Giorgia Ceselin, Zoi Salta, Julien Bloino, Nicola Tasinato, Vincenzo Barone. Accurate Quantum Chemical Spectroscopic Characterization of Glycolic Acid: A Route Toward its Astrophysical Detection.
The journal of physical chemistry. A.
2022 Apr; 126(15):2373-2387. doi:
10.1021/acs.jpca.2c01419. [PMID: 35384666] - Shengtang Li, Xuewen Shi, Bo Xu, Jian Wang, Peng Li, Xin Wang, Jinpeng Lou, Ziyao Li, Chengwei Yang, Songkai Li, Ping Zhen. In vitro drug release and antibacterial activity evaluation of silk fibroin coated vancomycin hydrochloride loaded poly (lactic-co-glycolic acid) (PLGA) sustained release microspheres.
Journal of biomaterials applications.
2022 04; 36(9):1676-1688. doi:
10.1177/08853282211064098. [PMID: 35015589] - Avni Nautiyal, Sarika Wairkar. Management of hyperpigmentation: Current treatments and emerging therapies.
Pigment cell & melanoma research.
2021 11; 34(6):1000-1014. doi:
10.1111/pcmr.12986. [PMID: 33998768] - Ankang Gu, Litao Zhang, Faku Ma, Xiangjun Kong. Induction of localized bullous pemphigoid on a young woman following a chemical peel.
Indian journal of dermatology, venereology and leprology.
2021 Sep; 87(5):706-708. doi:
10.25259/ijdvl_1116_20. [PMID: 34379953] - Pouria Jarsiah, Joerg Roehrich, Theresa Kueting, Walter Martz, Cornelius Hess. GHB related acids are useful in routine casework of suspected GHB intoxication cases.
Forensic science international.
2021 Jul; 324(?):110833. doi:
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Clinical journal of the American Society of Nephrology : CJASN.
2021 07; 16(7):1025-1036. doi:
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Photodiagnosis and photodynamic therapy.
2021 Jun; 34(?):102286. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2021 May; 46(10):2481-2488. doi:
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Biofabrication.
2021 03; 13(2):. doi:
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Forensic science international.
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Journal of cosmetic dermatology.
2020 Sep; 19(9):2349-2351. doi:
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Photosynthesis research.
2020 Jun; 144(3):361-372. doi:
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Journal of cosmetic dermatology.
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eLife.
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Biochimica et biophysica acta. Molecular basis of disease.
2020 03; 1866(3):165633. doi:
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Materials science & engineering. C, Materials for biological applications.
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Analytical chemistry.
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Reproductive toxicology (Elmsford, N.Y.).
2020 01; 91(?):74-91. doi:
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Journal of nanoscience and nanotechnology.
2019 12; 19(12):7539-7545. doi:
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Carbohydrate polymers.
2019 Nov; 223(?):115074. doi:
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In vivo (Athens, Greece).
2019 Sep; 33(5):1507-1519. doi:
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The New phytologist.
2019 09; 223(4):1762-1769. doi:
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International urology and nephrology.
2019 Jul; 51(7):1121-1127. doi:
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Nutrition research (New York, N.Y.).
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Forensic science international.
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Talanta.
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Journal of the American Society of Nephrology : JASN.
2018 06; 29(6):1615-1623. doi:
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Journal of dermatological science.
2018 Jan; 89(1):67-76. doi:
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Pediatric nephrology (Berlin, Germany).
2017 Nov; 32(11):2159-2163. doi:
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Facial plastic surgery : FPS.
2017 Oct; 33(5):545-550. doi:
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Annals of clinical biochemistry.
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Photosynthesis research.
2017 May; 132(2):183-196. doi:
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Plant physiology.
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Methods in molecular biology (Clifton, N.J.).
2017; 1653(?):97-104. doi:
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Methods in molecular biology (Clifton, N.J.).
2017; 1653(?):157-166. doi:
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Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.
2016 Dec; 24(12):911-915. doi:
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Phytochemistry.
2016 Dec; 132(?):26-32. doi:
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Annals of clinical biochemistry.
2016 Jul; 53(Pt 4):485-94. doi:
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Photosynthesis research.
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Biochimica et biophysica acta.
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Journal of experimental botany.
2016 05; 67(10):3041-52. doi:
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Journal of experimental botany.
2016 05; 67(10):3165-75. doi:
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The Plant journal : for cell and molecular biology.
2015 Nov; 84(4):718-32. doi:
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Journal of pharmaceutical and biomedical analysis.
2015 Oct; 114(?):16-21. doi:
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Plant physiology.
2015 Oct; 169(2):1042-61. doi:
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Journal of analytical toxicology.
2015 Jul; 39(6):481-5. doi:
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Clinical biochemistry.
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The Journal of biological chemistry.
2015 Jan; 290(3):1885-97. doi:
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PloS one.
2015; 10(3):e0118804. doi:
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Journal of biomaterials science. Polymer edition.
2015; 26(8):497-514. doi:
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The AAPS journal.
2015 Jan; 17(1):256-67. doi:
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Talanta.
2014 Dec; 130(?):470-4. doi:
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Annals of surgical oncology.
2014 Dec; 21 Suppl 4(?):S736-42. doi:
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Journal of medical genetics.
2014 Aug; 51(8):526-9. doi:
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Journal of drugs in dermatology : JDD.
2014 Jun; 13(6):678-83. doi:
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Pakistan journal of pharmaceutical sciences.
2014 Mar; 27(2):233-7. doi:
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Journal of chromatography. A.
2014 Jan; 1325(?):241-6. doi:
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Journal of biomaterials science. Polymer edition.
2014; 25(9):943-64. doi:
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Carbohydrate polymers.
2014 Jan; 99(?):284-90. doi:
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Phytochemistry.
2013 Nov; 95(?):168-76. doi:
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BMJ case reports.
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Plant biology (Stuttgart, Germany).
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Proceedings of the National Academy of Sciences of the United States of America.
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Annals of clinical biochemistry.
2013 Jan; 50(Pt 1):70-2. doi:
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Bioresource technology.
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Journal of proteome research.
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Biochimica et biophysica acta.
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Journal of pharmaceutical sciences.
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Physiologia plantarum.
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Plant signaling & behavior.
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Plant physiology and biochemistry : PPB.
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Journal of plant physiology.
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Journal of experimental botany.
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Transplant international : official journal of the European Society for Organ Transplantation.
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BMC plant biology.
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American journal of physiology. Renal physiology.
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