S-Methylglutathione (BioDeep_00000268163)
代谢物信息卡片
化学式: C11H19N3O6S (321.0994514)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N
InChI: InChI=1S/C11H19N3O6S/c1-21-5-7(10(18)13-4-9(16)17)14-8(15)3-2-6(12)11(19)20/h6-7H,2-5,12H2,1H3,(H,13,18)(H,14,15)(H,16,17)(H,19,20)/t6-,7-/m0/s1
描述信息
S-Methylglutathione is an S-substitued?glutathione and a stronger nucleophile than GSH[1]. S-Methylglutathione has inhibitory effect on glyoxalase 1[2].
同义名列表
2 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:141472
- PubChem: 115260
- DrugBank: DB04701
- ChEMBL: CHEMBL1233129
- KNApSAcK: C00051719
- CAS: 2922-56-7
- RefMet: S-Methylglutathione
- medchemexpress: HY-W009177
- KEGG: C11347
- PubChem: 13522
- KNApSAcK: 141472
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mercè Garcia-Belinchón, María Sánchez-Osuna, Laura Martínez-Escardó, Carla Granados-Colomina, Sònia Pascual-Guiral, Victoria Iglesias-Guimarais, Elisenda Casanelles, Judit Ribas, Victor J Yuste. An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
The Journal of biological chemistry.
2015 Aug; 290(34):20841-20855. doi:
10.1074/jbc.m115.644179. [PMID: 26124276] - Beverly J Wolpert, Max G Beauvoir, Elizabeth Fortson Wells, John M Hawdon. Plant vermicides of Haitian Vodou show in vitro activity against larval hookworm.
The Journal of parasitology.
2008 Oct; 94(5):1155-60. doi:
10.1645/ge-1446.1. [PMID: 18576795] - Maria Rius, Anne T Nies, Johanna Hummel-Eisenbeiss, Gabriele Jedlitschky, Dietrich Keppler. Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.
Hepatology (Baltimore, Md.).
2003 Aug; 38(2):374-84. doi:
10.1053/jhep.2003.50331. [PMID: 12883481] - N E Pettigrew, E J Brush, R F Colman. 3-Methyleneoxindole: an affinity label of glutathione S-transferase pi which targets tryptophan 38.
Biochemistry.
2001 Jun; 40(25):7549-58. doi:
10.1021/bi002840w. [PMID: 11412109] - O K Vatamaniuk, S Mari, Y P Lu, P A Rea. Mechanism of heavy metal ion activation of phytochelatin (PC) synthase: blocked thiols are sufficient for PC synthase-catalyzed transpeptidation of glutathione and related thiol peptides.
The Journal of biological chemistry.
2000 Oct; 275(40):31451-9. doi:
10.1074/jbc.m002997200. [PMID: 10807919] - A M Cantin, P Larivée, R O Bégin. Extracellular glutathione suppresses human lung fibroblast proliferation.
American journal of respiratory cell and molecular biology.
1990 Jul; 3(1):79-85. doi:
10.1165/ajrcmb/3.1.79. [PMID: 2363938] - K Hanai, H Kato, S Matsuhashi, H Morita, E W Raines, R Ross. Platelet proteins, including platelet-derived growth factor, specifically depress a subset of the multiple components of the response elicited by glutathione in Hydra.
The Journal of cell biology.
1987 Jun; 104(6):1675-81. doi:
10.1083/jcb.104.6.1675. [PMID: 3584244] - G Loo, J T Smith. Glutathione: an endogenous substrate for thiopurine methyltransferase?.
Biochemical and biophysical research communications.
1985 Feb; 126(3):1201-7. doi:
10.1016/0006-291x(85)90313-4. [PMID: 3977911]