Spinosad (BioDeep_00000002637)

   


代谢物信息卡片


Spinosad factor A

化学式: C41H65NO10 (731.4608)
中文名称: 多杀菌素
谱图信息: 最多检出来源 Viridiplantae(plant) 5.91%

分子结构信息

SMILES: CCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C=CC3C2CC(=O)O1)OC5C(C(C(C(O5)C)OC)OC)OC)C)OC6CCC(C(O6)C)N(C)C
InChI: InChI=1S/C41H65NO10/c1-10-26-12-11-13-34(52-36-17-16-33(42(5)6)23(3)48-36)22(2)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(47-9)39(46-8)38(45-7)24(4)49-41/h14-15,20,22-31,33-34,36,38-41H,10-13,16-19,21H2,1-9H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36+,38+,39-,40-,41+/m1/s1

描述信息

A spinosyn in which the sugar amino and hydroxy groups are globally methylated. One of the two active ingredients of spinosad.
CONFIDENCE standard compound; INTERNAL_ID 2635

同义名列表

4 个代谢物同义名

Spinosad factor A; Spinosyn A; Spinosad; Spinosyn A



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ASS1, EGFR, PIK3CA, SPN, SPTAN1
Peripheral membrane protein 1 CYP1B1
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 2 CYP1B1, EGFR
Cytoplasmic vesicle, autophagosome 1 GABARAP
Nucleus 4 EGFR, KDR, PPARA, SPN
autophagosome 1 GABARAP
cytosol 7 ASS1, GABARAP, KCNA1, LIPE, MAT1A, PIK3CA, SPTAN1
dendrite 1 KCNA1
nucleoplasm 3 ASS1, PPARA, SPN
Cell membrane 5 EGFR, KCNA1, KCNC1, KDR, LIPE
lamellipodium 1 PIK3CA
ruffle membrane 1 EGFR
Cell projection, axon 2 KCNA1, KCNC1
Early endosome membrane 1 EGFR
Multi-pass membrane protein 2 KCNA1, KCNC1
Golgi apparatus membrane 1 GABARAP
Synapse 1 KCNA1
cell cortex 1 SPTAN1
cell junction 4 EGFR, KCNA1, KDR, SPTAN1
cell surface 4 EGFR, KCNA1, KCNC1, SPN
glutamatergic synapse 2 EGFR, KCNA1
Golgi apparatus 1 KDR
Golgi membrane 2 EGFR, GABARAP
neuronal cell body 1 KCNA1
presynaptic membrane 2 KCNA1, KCNC1
smooth endoplasmic reticulum 1 GABARAP
Cytoplasm, cytosol 2 ASS1, LIPE
Lysosome 1 GABARAP
Presynapse 1 KCNA1
endosome 2 EGFR, KDR
plasma membrane 8 EGFR, GABARAP, KCNA1, KCNC1, KDR, PIK3CA, SPN, SPTAN1
Membrane 9 CYP1B1, EGFR, GABARAP, KCNA1, KCNC1, LIPE, PPP1R3A, SPN, SPTAN1
apical plasma membrane 2 EGFR, KCNA1
basolateral plasma membrane 1 EGFR
caveola 1 LIPE
extracellular exosome 3 ASS1, SPN, SPTAN1
endoplasmic reticulum 2 KCNA1, KDR
extracellular space 2 EGFR, SPN
perinuclear region of cytoplasm 2 EGFR, PIK3CA
intercalated disc 1 PIK3CA
mitochondrion 1 CYP1B1
protein-containing complex 1 EGFR
intracellular membrane-bounded organelle 2 CYP1B1, SPTAN1
Microsome membrane 1 CYP1B1
Single-pass type I membrane protein 2 EGFR, SPN
extracellular region 3 KDR, SPN, SPTAN1
Single-pass membrane protein 1 PPP1R3A
mitochondrial outer membrane 1 ASS1
neuronal cell body membrane 1 KCNC1
[Isoform 2]: Secreted 1 KDR
anchoring junction 2 KCNA1, KDR
nuclear membrane 1 EGFR
external side of plasma membrane 2 KDR, SPN
Extracellular vesicle 1 SPTAN1
actin cytoskeleton 2 GABARAP, SPTAN1
perikaryon 2 ASS1, KCNA1
cytoplasmic vesicle 2 GABARAP, KCNA1
microtubule cytoskeleton 1 SPTAN1
Early endosome 1 KDR
postsynaptic membrane 2 KCNA1, KCNC1
Membrane raft 2 EGFR, KDR
Cytoplasm, cytoskeleton 2 GABARAP, SPTAN1
focal adhesion 1 EGFR
microtubule 1 GABARAP
axolemma 1 KCNC1
GABA-ergic synapse 1 GABARAP
basement membrane 1 SPN
intracellular vesicle 1 EGFR
Nucleus, PML body 1 SPN
PML body 1 SPN
axoneme 1 GABARAP
receptor complex 2 EGFR, KDR
chromatin 2 PPARA, SPN
microtubule associated complex 1 GABARAP
Cytoplasmic vesicle, autophagosome membrane 1 GABARAP
autophagosome membrane 1 GABARAP
cell projection 1 SPTAN1
cytoskeleton 1 GABARAP
Cytoplasm, cell cortex 1 SPTAN1
sperm midpiece 1 GABARAP
fibrillar center 1 SPN
Endomembrane system 1 GABARAP
sorting endosome 1 KDR
microvillus 1 SPN
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Cell projection, microvillus 1 SPN
cell body fiber 1 ASS1
axon initial segment 1 KCNA1
Cell projection, dendrite 1 KCNA1
Presynaptic cell membrane 2 KCNA1, KCNC1
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
voltage-gated potassium channel complex 2 KCNA1, KCNC1
cortical actin cytoskeleton 1 SPTAN1
axon terminus 2 KCNA1, KCNC1
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
specific granule lumen 1 SPTAN1
tertiary granule lumen 1 SPTAN1
paranode region of axon 1 KCNA1
calyx of Held 2 KCNA1, KCNC1
clathrin-coated endocytic vesicle membrane 1 EGFR
uropod 1 SPN
spectrin 1 SPTAN1
dendrite membrane 1 KCNC1
Cell projection, uropodium 1 SPN
protein phosphatase type 1 complex 1 PPP1R3A
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
[CD43 cytoplasmic tail]: Nucleus 1 SPN
juxtaparanode region of axon 1 KCNA1
methionine adenosyltransferase complex 1 MAT1A
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
organelle 1 SPTAN1


文献列表

  • Ryan J Smith, Yinting Chen, Christine Isabelle Lafleur, Diljot Kaur, Jacqueline C Bede. Effect of sublethal concentrations of the bioinsecticide spinosyn treatment of Trichoplusia ni eggs on the caterpillar and its parasitoid, Trichogramma brassicae. Pest management science. 2024 Jan; ?(?):. doi: 10.1002/ps.8004. [PMID: 38298017]
  • Sinue I Morales, Ana M Martínez, José I Figueroa, Jesús Campos-García, Alberto Gómez-Tagle, Philippe Lobit, Guy Smagghe, Samuel Pineda. Foliar persistence and residual activity of four insecticides of different mode of action on the predator Engytatus varians (Hemiptera: Miridae). Chemosphere. 2019 Nov; 235(?):76-83. doi: 10.1016/j.chemosphere.2019.06.163. [PMID: 31255768]