Moxifloxacin (BioDeep_00000002548)

   

human metabolite blood metabolite Chemicals and Drugs Volatile Flavor Compounds


代谢物信息卡片


7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

化学式: C21H24FN3O4 (401.1750756)
中文名称: 1-环丙基-7-(2,8-二氮杂双环[4.3.0]壬烷-8-基)-6-氟-8-甲氧基-4-氧代喹啉-3-甲酸, 莫西沙星
谱图信息: 最多检出来源 Homo sapiens(blood) 13.48%

分子结构信息

SMILES: COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
InChI: InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)

描述信息

Moxifloxacin is only found in individuals that have used or taken this drug. It is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.The bactericidal action of moxifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01M - Quinolone antibacterials > J01MA - Fluoroquinolones
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AE - Fluoroquinolones
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
D004791 - Enzyme Inhibitors
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

16 个代谢物同义名

7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylate; 1-cyclopropyl-6-fluoro-8-methoxy-7-(octahydro-6h-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl--7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-quinoline-3-carboxylic acid; Moxifloxacin hydrochloride; Moxifloxacin; BAY 12-8039; Octegra; Proflox; Avelox; Actira; Avalox; Izilox; Moxifloxacin



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuanqin Du, Jingjing Huang, Yaobin Nong, Ruixi Zhong, Ronghuo Zhu, Wenxuan Song, Hongna Huang, Qinwen Tan, Jian Xu, Xiyu Xiao, Juhong Jia. A case of ascetic fluid Mycobacterium aubagnense infection in a patient with severe peritoneal effusion. BMC infectious diseases. 2023 Feb; 23(1):84. doi: 10.1186/s12879-023-08041-1. [PMID: 36750816]
  • Alicja Chrzanowska, Dagmara Kurpios-Piec, Barbara Żyżyńska-Granica, Ewelina Kiernozek-Kalińska, Wen Xin Lay, Andrzej K Ciechanowicz, Marta Struga. Anticancer activity and metabolic alteration in colon and prostate cancer cells by novel moxifloxacin conjugates with fatty acids. European journal of pharmacology. 2023 Feb; 940(?):175481. doi: 10.1016/j.ejphar.2022.175481. [PMID: 36566005]
  • Haiyan Sun, Xinlou Chai, Guangxun Xu, Shuangying Wei. The Formation and Drug Resistance Mechanism of Biofilm for Streptococcus pneumoniae Infection in Severe Respiratory Patients. Cellular and molecular biology (Noisy-le-Grand, France). 2023 Jan; 69(1):75-80. doi: 10.14715/cmb/2022.69.1.13. [PMID: 37213152]
  • Iurii Mochalov, Maryna Kryvtsova, Andrij Chobey, Mariya Kulynych. Identification of Pathogenic Microflora and Its Sensitivity to Antibiotics in Cases of the Odontogenic Purulent Periostitis and Abscesses in the Oral Cavity. Prague medical report. 2023; 124(1):16-32. doi: 10.14712/23362936.2023.2. [PMID: 36763828]
  • Merve Eylul Kiymaci, Gizem Ruya Topal, Ozgur Esim, Merve Bacanli, Cansel Kose Ozkan, Onur Erdem, Ayhan Savaser, Yalcin Ozkan. Evaluation of bacterial uptake, antibacterial efficacy against Escherichia coli, and cytotoxic effects of moxifloxacin-loaded solid lipid nanoparticles. Arhiv za higijenu rada i toksikologiju. 2022 Dec; 73(4):260-269. doi: 10.2478/aiht-2022-73-3667. [PMID: 36607722]
  • Fatih Donmez, Abdulahad Dogan. Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues. Drug and chemical toxicology. 2022 Nov; 45(6):2686-2698. doi: 10.1080/01480545.2021.1982624. [PMID: 34601990]
  • Prashant D Tailor, Marybeth K Farazdaghi, Sanjay V Patel, Keith H Baratz. Oleander-Associated Keratitis and Uveitis. Cornea. 2022 Oct; 41(10):1305-1307. doi: 10.1097/ico.0000000000003032. [PMID: 36107850]
  • Muthumariappan Akilarasan, Elayappan Tamilalagan, Shen-Ming Chen, Selvarasu Maheshwaran, Chih-Hsuan Fan, Mohamed A Habila, Mika Sillanpää. Rational synthesis of rare-earth lanthanum molybdate covered reduced graphene oxide nanocomposites for the voltammetric detection of Moxifloxacin hydrochloride. Bioelectrochemistry (Amsterdam, Netherlands). 2022 Aug; 146(?):108145. doi: 10.1016/j.bioelechem.2022.108145. [PMID: 35550254]
  • Xiaocui Wu, Guangkun Tan, Jinghui Yang, Yinjuan Guo, Chengchen Huang, Wei Sha, Fangyou Yu. Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2022 Aug; 121(?):47-54. doi: 10.1016/j.ijid.2022.04.061. [PMID: 35523300]
  • Xiaocui Wu, Guangkun Tan, Wei Sha, Haican Liu, Jinghui Yang, Yinjuan Guo, Xin Shen, Zheyuan Wu, Hongbo Shen, Fangyou Yu. Use of Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Complex Drug Resistance from Early Positive Liquid Cultures. Microbiology spectrum. 2022 04; 10(2):e0251621. doi: 10.1128/spectrum.02516-21. [PMID: 35311541]
  • Carlijn H C Litjens, Laurens F M Verscheijden, Celine Bolwerk, Rick Greupink, Jan B Koenderink, Petra H H van den Broek, Jeroen J M W van den Heuvel, Elin M Svensson, Martin J Boeree, Cecile Magis-Escurra, Wouter Hoefsloot, Reinout van Crevel, Arjan van Laarhoven, Jakko van Ingen, Saskia Kuipers, Rovina Ruslami, David M Burger, Frans G M Russel, Rob E Aarnoutse, Lindsey H M Te Brake. Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling. Journal of clinical pharmacology. 2022 03; 62(3):385-396. doi: 10.1002/jcph.1972. [PMID: 34554580]
  • Xin Wen, Cong Shen, Jinyu Xia, Lan-Lan Zhong, Zhongwen Wu, Mohamed Abd El-Gawad El-Sayed Ahmed, Nana Long, Furong Ma, Guili Zhang, Wenwei Wu, Jianlve Luo, Yong Xia, Min Dai, Liyan Zhang, Kang Liao, Siyuan Feng, Cha Chen, Yishen Chen, Wenji Luo, Guo-Bao Tian. Whole-Genome Sequencing Reveals the High Nosocomial Transmission and Antimicrobial Resistance of Clostridioides difficile in a Single Center in China, a Four-Year Retrospective Study. Microbiology spectrum. 2022 02; 10(1):e0132221. doi: 10.1128/spectrum.01322-21. [PMID: 35019676]
  • Obaidur Rehman, Sudesh Kumar Arya, Ujjwal Prakash Jha, Shifali Nayyar, Itisha Goel. Herpes Zoster Ophthalmicus After COVID-19 Vaccination: Chance Occurrence or More?. Cornea. 2022 Feb; 41(2):254-256. doi: 10.1097/ico.0000000000002881. [PMID: 34690265]
  • Josefine Slater, Maiken Stilling, Pelle Hanberg, Mathias Alrø Fichtner Bendtsen, Andrea René Jørgensen, Kjeld Søballe, Nis Pedersen Jørgensen, Mats Bue. Moxifloxacin Concentrations in the Knee Joint, Tibial Bone, and Soft Tissue When Combined with Rifampicin: A Randomized Porcine Microdialysis Study. The Journal of bone and joint surgery. American volume. 2022 01; 104(1):49-54. doi: 10.2106/jbjs.21.00549. [PMID: 34731098]
  • Yuan Sun, Ling Cong, Song Yang, Rui Zhao, Zhuoling An, Lihong Liu. Moxifloxacin Induced Liver Injury by Causing Lachnospiraceae Deficiency and Interfering with Butyric Acid Production through Gut-Liver Axis. Disease markers. 2022; 2022(?):9302733. doi: 10.1155/2022/9302733. [PMID: 35531479]
  • Ashit Trivedi, Cheng-Pang Hsu, Pegah Jafarinasabian, Bianca Terminello, Hanze Zhang, Stephen Flach, Samuel Israel, Ashley Brooks, Hongqi Xue, Borje Darpo, Siddique Abbasi, Sandeep Dutta, Edward Lee. Omecamtiv mecarbil does not prolong QTc intervals at therapeutic concentrations. British journal of clinical pharmacology. 2022 01; 88(1):187-198. doi: 10.1111/bcp.14939. [PMID: 34131942]
  • Atiqah Amran, Ching Yee Tan, Ka-Liong Tan, Ranald Malcom Ho, Anil Kumar Anand, Chuei Wuei Leong. Pharmacokinetics and Bioequivalence Study of a New Branded Generic Moxifloxacin Tablet Among Healthy Volunteers. Clinical pharmacology in drug development. 2021 12; 10(12):1514-1518. doi: 10.1002/cpdd.964. [PMID: 34107173]
  • Salma Luaiby Dahash, Salah Burhan Al-Windy, Azhar Hatif Al-Kuraishi, Nawar Raad Hussien, Marwa Salih Al-Niemi, Hayder Mutter Al-Kuraishy. Ellagic acid-rich Pomegranate extracts synergizes moxifloxacin against methicillin resistance Staphylococcus aureus (MRSA). JPMA. The Journal of the Pakistan Medical Association. 2021 Dec; 71(Suppl 8)(12):S88-S92. doi: ". [PMID: 35130226]
  • Mahwish Akhtar, Somia Gul, Sana Shamim, Rubina Siddiqui. Simultaneous determination of moxifloxacin with NSAIDs in API, dosage and serum by reverse phase high-performance liquid chromatography: Application to in vitro drug interactions. Pakistan journal of pharmaceutical sciences. 2021 Nov; 34(6):2091-2099. doi: NULL. [PMID: 35034869]
  • Lloyd Tanner, Gabriel T Mashabela, Charles C Omollo, Timothy J de Wet, Christopher J Parkinson, Digby F Warner, Richard K Haynes, Lubbe Wiesner. Intracellular Accumulation of Novel and Clinically Used TB Drugs Potentiates Intracellular Synergy. Microbiology spectrum. 2021 10; 9(2):e0043421. doi: 10.1128/spectrum.00434-21. [PMID: 34585951]
  • George P Allen, Kristina M Deao, Stephanie A Hill, Sandra M Schipelliti, Thomas Tran. In vitro evaluation of antimicrobial resistance selection in Neisseria gonorrhoeae. International journal of antimicrobial agents. 2021 Oct; 58(4):106417. doi: 10.1016/j.ijantimicag.2021.106417. [PMID: 34391903]
  • Rita M Pinto, Claudia Monteiro, Sofia A Costa Lima, Susana Casal, Patrick Van Dijck, M Cristina L Martins, Cláudia Nunes, Salette Reis. N-Acetyl-l-cysteine-Loaded Nanosystems as a Promising Therapeutic Approach Toward the Eradication of Pseudomonas aeruginosa Biofilms. ACS applied materials & interfaces. 2021 Sep; 13(36):42329-42343. doi: 10.1021/acsami.1c05124. [PMID: 34464076]
  • Ramesh Boinpally, Brian McNamee, Li Yao, Matthew Butler, Danielle McGeeney, Lisa Borbridge, Antonia Periclou. A Single Supratherapeutic Dose of Atogepant Does Not Affect Cardiac Repolarization in Healthy Adults: Results From a Randomized, Single-Dose, Phase 1 Crossover Trial. Clinical pharmacology in drug development. 2021 09; 10(9):1099-1107. doi: 10.1002/cpdd.940. [PMID: 33942560]
  • Sudhakar M Pai, Hiroyuki Yamada, Robert B Kleiman, Rui Zhuo, Qingtao Mike Huang, Ryosuke Koretomo. Thorough QT/QTc Evaluation of the Cardiac Safety of Enarodustat (JTZ-951), an Oral Erythropoiesis-Stimulating Agent, in Healthy Adults. Clinical pharmacology in drug development. 2021 08; 10(8):884-898. doi: 10.1002/cpdd.933. [PMID: 34159762]
  • Gang Fang, Ning-Chang Cheng, Li-Li Huang, Wei-Ping Xie, Chun-Mei Hu, Wei Chen. The first report of co-existence of pulmonary tuberculosis and lung malignancy in a kidney transplant recipient: a case report and literature review. BMC infectious diseases. 2021 Jul; 21(1):629. doi: 10.1186/s12879-021-06350-x. [PMID: 34210287]
  • Li Yu, Congcong Yan, Shanshan Chu, Yingjun Chen, Junwei Wang. The differential diagnosis of pneumonia in two patients infected by atypical pathogens. Future microbiology. 2021 07; 16(11):769-776. doi: 10.2217/fmb-2021-0127. [PMID: 34253052]
  • Lei Tang, Xianchun Zeng. One-year Follow-up after Severe SARS-CoV-2 Pneumonia. Radiology. 2021 07; 300(1):E310. doi: 10.1148/radiol.2021210615. [PMID: 33787340]
  • Jinju Guk, Jérémie Guedj, Charles Burdet, Antoine Andremont, Jean de Gunzburg, Annie Ducher, France Mentré. Modeling the Effect of DAV132, a Novel Colon-Targeted Adsorbent, on Fecal Concentrations of Moxifloxacin and Gut Microbiota Diversity in Healthy Volunteers. Clinical pharmacology and therapeutics. 2021 04; 109(4):1045-1054. doi: 10.1002/cpt.1977. [PMID: 32617960]
  • Zeynep Kayaarasi Ozturker. Conjunctivitis as sole symptom of COVID-19: A case report and review of literature. European journal of ophthalmology. 2021 Mar; 31(2):NP161-NP166. doi: 10.1177/1120672120946287. [PMID: 32703010]
  • Ting Hu, Yuan Sun, Han Li, Ping Du, Lihong Liu, Zhuoling An. Dual derivatization strategy for the comprehensive quantification and double bond location characterization of fatty acids by ultra-high performance liquid chromatography-tandem mass spectrometry. Journal of chromatography. A. 2021 Feb; 1639(?):461939. doi: 10.1016/j.chroma.2021.461939. [PMID: 33530009]
  • Erkan Ozcan, Serap Yavuzer, Betul Borku Uysal, Mehmet Sami Islamoglu, Hande Ikitimur, Omer Faruk Unal, Yunus Emre Akpinar, Serhat Seyhan, Suna Koc, Hakan Yavuzer, Mahir Cengiz. The relationship between positivity for COVID-19 RT-PCR and symptoms, clinical findings, and mortality in Turkey. Expert review of molecular diagnostics. 2021 02; 21(2):245-250. doi: 10.1080/14737159.2021.1882305. [PMID: 33496627]
  • Dong Liang, Jing Ma, Bo Wei. Oral absorption and drug interaction kinetics of moxifloxacin in an animal model of weightlessness. Scientific reports. 2021 01; 11(1):2605. doi: 10.1038/s41598-021-82044-3. [PMID: 33510326]
  • Lichao Fan, Huan Liu, Na Li, Chang Liu, Ye Gu, Yongyu Liu, Yu Chen. Medical treatment of 55 patients with COVID-19 from seven cities in northeast China who fully recovered: A single-center, retrospective, observational study. Medicine. 2021 Jan; 100(2):e23923. doi: 10.1097/md.0000000000023923. [PMID: 33466134]
  • Tingyu Yan, Zhongxu Ma, Jingjing Liu, Na Yin, Shizhen Lei, Xinxin Zhang, Xuedong Li, Yu Zhang, Jun Kong. Thermoresponsive GenisteinNLC-dexamethasone-moxifloxacin multi drug delivery system in lens capsule bag to prevent complications after cataract surgery. Scientific reports. 2021 01; 11(1):181. doi: 10.1038/s41598-020-80476-x. [PMID: 33420301]
  • Stacey L P Scroggs, Danielle K Offerdahl, Dylan P Flather, Ciera N Morris, Benjamin L Kendall, Rebecca M Broeckel, Paul A Beare, Marshall E Bloom. Fluoroquinolone Antibiotics Exhibit Low Antiviral Activity against SARS-CoV-2 and MERS-CoV. Viruses. 2020 12; 13(1):. doi: 10.3390/v13010008. [PMID: 33374514]
  • Krzysztof Marciniec, Artur Beberok, Paweł Pęcak, Stanisław Boryczka, Dorota Wrześniok. Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis. Pharmacological reports : PR. 2020 Dec; 72(6):1553-1561. doi: 10.1007/s43440-020-00169-0. [PMID: 33063271]
  • Shaojia Lu, Ning Wei, Jiajun Jiang, Lingling Wu, Jifang Sheng, Jianying Zhou, Qiang Fang, Yu Chen, Shufa Zheng, Feng Chen, Tingbo Liang, Shaohua Hu. First report of manic-like symptoms in a COVID-19 patient with no previous history of a psychiatric disorder. Journal of affective disorders. 2020 12; 277(?):337-340. doi: 10.1016/j.jad.2020.08.031. [PMID: 32858315]
  • Yaguang Hu, Tianyan Chen, Miaomiao Liu, Li Zhang, Fang Wang, Shuo Zhao, Hui Liu, Han Xia, Yawen Wang, Li Li. Positive detection of SARS-CoV-2 combined HSV1 and HHV6B virus nucleic acid in tear and conjunctival secretions of a non-conjunctivitis COVID-19 patient with obstruction of common lacrimal duct. Acta ophthalmologica. 2020 Dec; 98(8):859-863. doi: 10.1111/aos.14456. [PMID: 32406606]
  • Zhi Xu. 1,2,3-Triazole-containing hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). European journal of medicinal chemistry. 2020 Nov; 206(?):112686. doi: 10.1016/j.ejmech.2020.112686. [PMID: 32795773]
  • Valeria Tellone, Maria Teresa Rosignoli, Rossella Picollo, Patrizia Dragone, Alessandra Del Vecchio, Alessandro Comandini, Milko Radicioni, Chiara Leuratti, Fabrizio Calisti. Effect of 3 Single Doses of Trazodone on QTc Interval in Healthy Subjects. Journal of clinical pharmacology. 2020 11; 60(11):1483-1495. doi: 10.1002/jcph.1640. [PMID: 32488885]
  • Defang Ding, Caisong Zhu, Weiwu Yao. A Cured Patient With 2019-nCoV Pneumonia. The American journal of medicine. 2020 11; 133(11):1291-1292. doi: 10.1016/j.amjmed.2020.02.023. [PMID: 32205073]
  • Katarina Ilic, Ivy Song, Jingyang Wu, Patrick Martin. Evaluation of the Effect of Maribavir on Cardiac Repolarization in Healthy Participants: Thorough QT/QTc Study. Clinical and translational science. 2020 11; 13(6):1260-1270. doi: 10.1111/cts.12814. [PMID: 32506738]
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  • Azmi Nasser, Shamia L Faison, Tesfaye Liranso, Toyin Adewole, Gregory D Busse, Maurizio Fava, Robert B Kleiman, Stefan Schwabe. Evaluation of the Effect of SPN-812 (Viloxazine Extended-Release) on QTc Interval in Healthy Adults. The Journal of clinical psychiatry. 2020 10; 81(6):. doi: 10.4088/jcp.20m13395. [PMID: 33049804]
  • Li-Yu Liang, Ying-Chun He, Yun-Fei Li, Juan Yang, Feng-Yan Xu, Lu-Jin Li, Ji-Han Huang, Kun Wang, Qing-Shan Zheng. Relationship between antofloxacin concentration and QT prolongation and estimation of the possible false-positive rate. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2020 Oct; 130(?):110619. doi: 10.1016/j.biopha.2020.110619. [PMID: 32795925]
  • Irene Karampela, Maria Dalamaga. Could Respiratory Fluoroquinolones, Levofloxacin and Moxifloxacin, Prove to be Beneficial as an Adjunct Treatment in COVID-19?. Archives of medical research. 2020 10; 51(7):741-742. doi: 10.1016/j.arcmed.2020.06.004. [PMID: 32546446]
  • Svetlana N Kondratenko, Irina V Zolkina, Eugenia V Shikh. A study of the pharmacokinetics of moxifloxacin by the dynamics of its distribution in the blood plasma and saliva of healthy volunteers: a comparative analysis and possible extrapolation methods. Drug metabolism and personalized therapy. 2020 09; 35(4):. doi: 10.1515/dmpt-2020-0115. [PMID: 34704694]
  • K Iqbal, A Broeker, H Nowak, T Rahmel, A Nussbaumer-Pröll, Z Österreicher, M Zeitlinger, S G Wicha. A pharmacometric approach to define target site-specific breakpoints for bacterial killing and resistance suppression integrating microdialysis, time-kill curves and heteroresistance data: a case study with moxifloxacin. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2020 Sep; 26(9):1255.e1-1255.e8. doi: 10.1016/j.cmi.2020.02.013. [PMID: 32088331]
  • Feng He, Qingqing Luo, Ming Lei, Lixin Fan, Xinning Shao, Kaiyuan Hu, Shuguang Qin, Na Yu, Jie Cao, Liuping Yang. Successful recovery of recurrence of positive SARS-CoV-2 RNA in COVID-19 patient with systemic lupus erythematosus: a case report and review. Clinical rheumatology. 2020 Sep; 39(9):2803-2810. doi: 10.1007/s10067-020-05230-0. [PMID: 32725351]
  • Ming-Cheng Chang, Yu-Jen Kuo, Kuo-Hsuan Hung, Cheng-Liang Peng, Kuan-Yin Chen, Lung-Kun Yeh. Liposomal dexamethasone-moxifloxacin nanoparticle combinations with collagen/gelatin/alginate hydrogel for corneal infection treatment and wound healing. Biomedical materials (Bristol, England). 2020 08; 15(5):055022. doi: 10.1088/1748-605x/ab9510. [PMID: 32434164]
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  • Josefine Slater, Pelle Hanberg, Mathias Alrø Fichtner Bendtsen, Andrea René Jørgensen, Eva Greibe, Kjeld Søballe, Mats Bue, Nis Pedersen Jørgensen, Maiken Stilling. Effects of rifampicin on moxifloxacin concentrations in porcine cervical spine: a randomized microdialysis study. The Journal of antimicrobial chemotherapy. 2020 08; 75(8):2206-2212. doi: 10.1093/jac/dkaa153. [PMID: 32413120]
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