Diflubenzuron (BioDeep_00000002529)

 

Secondary id: BioDeep_00000397585

human metabolite Endogenous Volatile Flavor Compounds


代谢物信息卡片


N-[[(4-Chlorophenyl)amino]carbonyl]-2,6-difluorobenzamide, 9ci

化学式: C14H9ClF2N2O2 (310.03205879999996)
中文名称: 氟脲杀, 二氟苯脲
谱图信息: 最多检出来源 Escherichia coli(natural_products) 75%

分子结构信息

SMILES: C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC=C(C=C2)Cl)F
InChI: InChI=1S/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Xiang Li, Lili Du, Xiaofeng Lu, Shuai Wang, Xiaoxiao Liu, Licheng Wang, Yong Guo. In situ growth of ZIF-67 to construct core-shell mosaic structural composites for efficient extraction of benzoylurea insecticides. Mikrochimica acta. 2024 01; 191(2):90. doi: 10.1007/s00604-023-06154-7. [PMID: 38214747]
  • Lu Qiao, Lu Chen, Zhen Yang, Jinhua Xu, Jinlong Song, Xingyang Li, Huiwu Sun, Yingchun Mu. Bioaccumulation and elimination, acute toxicity analysis and risk assessment of diflubenzuron in common carp (Cyprinus carpio). Chemosphere. 2023 Jun; 335(?):139154. doi: 10.1016/j.chemosphere.2023.139154. [PMID: 37290502]
  • Hend H A Salem, Shaimaa H Mohammed, Randa I Eltaly, Moataz A M Moustafa, Adrien Fónagy, Shaimaa M Farag. Co-application of entomopathogenic fungi with chemical insecticides against Culex pipiens. Journal of invertebrate pathology. 2023 Mar; 198(?):107916. doi: 10.1016/j.jip.2023.107916. [PMID: 37004917]
  • Daoshuai Huang, Shaonan Li, Yu Lu, Meng Sha, Jiaxin Li. Effects of diflubenzuron on shrimp (Neocaridina palmata) in freshwater systems dominated by submerged plant (Ceratophyllum demersum). Chemosphere. 2023 Feb; 313(?):137567. doi: 10.1016/j.chemosphere.2022.137567. [PMID: 36529168]
  • Xiang Li, Xiaofeng Lu, Xiaojing Liang, Yong Guo, Licheng Wang, Shuai Wang. Extraction of benzoylurea insecticides from tea leaves based on thermoplastic polyethyleneimine embedded magnetic nanoparticle carbon materials. Journal of chromatography. A. 2022 Oct; 1681(?):463476. doi: 10.1016/j.chroma.2022.463476. [PMID: 36088774]
  • Emmanouil A Fotakis, Konstantinos Mavridis, Anastasia Kampouraki, Sofia Balaska, Filianna Tanti, George Vlachos, Sandra Gewehr, Spiros Mourelatos, Antonios Papadakis, Maria Kavalou, Dimitrios Nikolakakis, Maria Moisaki, Nikolaos Kampanis, Manolis Loumpounis, John Vontas. Mosquito population structure, pathogen surveillance and insecticide resistance monitoring in urban regions of Crete, Greece. PLoS neglected tropical diseases. 2022 02; 16(2):e0010186. doi: 10.1371/journal.pntd.0010186. [PMID: 35176020]
  • Abdulwahab M Hafez. Risk assessment of resistance to diflubenzuron in Musca domestica: Realized heritability and cross-resistance to fourteen insecticides from different classes. PloS one. 2022; 17(5):e0268261. doi: 10.1371/journal.pone.0268261. [PMID: 35560149]
  • Esra Nalinci, Mehmet Karagoz, Baris Gulcu, Derya Ulug, Sebnem Hazal Gulsen, Harun Cimen, Mustapha Touray, David Shapiro-Ilan, Selcuk Hazir. The effect of chemical insecticides on the scavenging performance of Steinernema carpocapsae: Direct effects and exposure to insects killed by chemical insecticides. Journal of invertebrate pathology. 2021 09; 184(?):107641. doi: 10.1016/j.jip.2021.107641. [PMID: 34186086]
  • Qiong Yao, Lin-Fa Quan, Shu Xu, Yi-Zhi Dong, Wen-Jing Li, Bing-Xu Chen. Effect of diflubenzuron on the chitin biosynthesis pathway in Conopomorpha sinensis eggs. Insect science. 2021 Aug; 28(4):1061-1075. doi: 10.1111/1744-7917.12848. [PMID: 32686293]
  • Woonghee Lee, Garam An, Hahyun Park, Whasun Lim, Gwonhwa Song. Diflubenzuron leads to apoptotic cell death through ROS generation and mitochondrial dysfunction in bovine mammary epithelial cells. Pesticide biochemistry and physiology. 2021 Aug; 177(?):104893. doi: 10.1016/j.pestbp.2021.104893. [PMID: 34301355]
  • André Luiz N Silva, Robson Andrade Rodrigues, Mayara Schueroff Siqueira, Karine Nathiele Nogueira Farias, Karin Virgínia Kuibida, Lilian Franco-Belussi, Carlos E Fernandes. Transaminase profile and hepatic histopathological traits in Piaractus mesopotamicus exposed to insecticide Diflubenzuron. Environmental science and pollution research international. 2021 May; 28(17):22002-22010. doi: 10.1007/s11356-020-12013-2. [PMID: 33410075]
  • Christos I Rumbos, Christos G Athanassiou. Assessment of selected larvicides for the control of Culex pipiens biotype pipiens and Culex pipiens biotype molestus under laboratory and semi-field conditions. Pest management science. 2020 Nov; 76(11):3568-3576. doi: 10.1002/ps.5847. [PMID: 32533802]
  • Nurper Guz, Naciye Sena Cagatay, Emmanouil A Fotakis, Enver Durmusoglu, John Vontas. Detection of diflubenzuron and pyrethroid resistance mutations in Culex pipiens from Muğla, Turkey. Acta tropica. 2020 Mar; 203(?):105294. doi: 10.1016/j.actatropica.2019.105294. [PMID: 31836282]
  • Falin He, Shiang Sun, Xiao Sun, Shoumin Ji, Xiangdong Li, Jiwang Zhang, Xingyin Jiang. Effects of insect growth-regulator insecticides on the immature stages of Harmonia axyridis (Coleoptera: Coccinellidae). Ecotoxicology and environmental safety. 2018 Nov; 164(?):665-674. doi: 10.1016/j.ecoenv.2018.08.076. [PMID: 30170315]
  • Huili Wang, Yun Xie, Meng Jiao, Xiao Hu, Jitong Li, Peng Xu, Yanfeng Zhang, Jing Chang. Metabolism of Diflubenzuron in Lizard ( Eremias argus) and Comparative Toxicity of Diflubenzuron and Its Metabolite. Journal of agricultural and food chemistry. 2018 Nov; 66(44):11640-11646. doi: 10.1021/acs.jafc.8b03713. [PMID: 30346759]
  • Jing Chang, Jitong Li, Weiyu Hao, Huili Wang, Wei Li, Baoyuan Guo, Jianzhong Li, Yinghuan Wang, Peng Xu. The body burden and thyroid disruption in lizards (Eremias argus) living in benzoylurea pesticides-contaminated soil. Journal of hazardous materials. 2018 04; 347(?):218-226. doi: 10.1016/j.jhazmat.2018.01.005. [PMID: 29316515]
  • Pengqiang Du, Xiaohu Wu, Jun Xu, Fengshou Dong, Yingchun Shi, Yuanbo Li, Xingang Liu, Yongquan Zheng. Different residue behaviors of four pesticides in mushroom using two different application methods. Environmental science and pollution research international. 2018 Mar; 25(9):8377-8387. doi: 10.1007/s11356-017-1142-4. [PMID: 29307062]
  • Jing Chang, Huili Wang, Peng Xu, Baoyuan Guo, Jianzhong Li, Yinghuan Wang, Wei Li. Oral and dermal diflubenzuron exposure causes a hypothalamic-pituitary-thyroid (HPT) axis disturbance in the Mongolian racerunner (Eremias argus). Environmental pollution (Barking, Essex : 1987). 2018 Jan; 232(?):338-346. doi: 10.1016/j.envpol.2017.08.115. [PMID: 29017816]
  • Jing Chang, Wei Li, Peng Xu, Baoyuan Guo, Yinghuan Wang, Jianzhong Li, Huili Wang. The tissue distribution, metabolism and hepatotoxicity of benzoylurea pesticides in male Eremias argus after a single oral administration. Chemosphere. 2017 Sep; 183(?):1-8. doi: 10.1016/j.chemosphere.2017.05.009. [PMID: 28511076]
  • Ricardo Alcántara-de la Cruz, José Cola Zanuncio, Mabio Chrisley Lacerda, Carlos Frederico Wilcken, Flávio Lemes Fernandes, Wagner de Souza Tavares, Marcus Alvarenga Soares, Carlos Sigueyuki Sediyama. Side-effects of pesticides on the generalist endoparasitoid Palmistichus elaeisis (Hymenoptera: Eulophidae). Scientific reports. 2017 08; 7(1):10064. doi: 10.1038/s41598-017-10462-3. [PMID: 28855720]
  • Pengqiang Du, Xiaohu Wu, Hairong He, Ying Zhang, Jun Xu, Fengshou Dong, Yongquan Zheng, Xingang Liu. Evaluation of the safe use and dietary risk of beta-cypermethrin, pyriproxyfen, avermectin, diflubenzuron and chlorothalonil in button mushroom. Scientific reports. 2017 08; 7(1):8694. doi: 10.1038/s41598-017-07860-y. [PMID: 28821721]
  • Nishikant Wase, Boqiang Tu, James W Allen, Paul N Black, Concetta C DiRusso. Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae. Plant physiology. 2017 Aug; 174(4):2146-2165. doi: 10.1104/pp.17.00433. [PMID: 28652262]
  • W Guo, X Yan, G Zhao, R Han. Increased Efficacy of Entomopathogenic Nematode-Insecticide Combinations Against Holotrichia oblita (Coleoptera: Scarabaeidae). Journal of economic entomology. 2017 02; 110(1):41-51. doi: 10.1093/jee/tow241. [PMID: 28017929]
  • F Shang, Y Xiong, W-K Xia, D-D Wei, D Wei, J-J Wang. Identification, characterization and functional analysis of a chitin synthase gene in the brown citrus aphid, Toxoptera citricida (Hemiptera, Aphididae). Insect molecular biology. 2016 08; 25(4):422-30. doi: 10.1111/imb.12228. [PMID: 26991909]
  • Frédéric Darriet. An anti-mosquito mixture for domestic use, combining a fertiliser and a chemical or biological larvicide. Pest management science. 2016 Jul; 72(7):1340-5. doi: 10.1002/ps.4157. [PMID: 26414239]
  • Tayrine Paschoaletti Benze, Marise Margareth Sakuragui, Lucas Henrique de Paula Zago, Marisa Narciso Fernandes. Subchronic exposure to diflubenzuron causes health disorders in neotropical freshwater fish, Prochilodus lineatus. Environmental toxicology. 2016 May; 31(5):533-42. doi: 10.1002/tox.22065. [PMID: 25359229]
  • Aline Lima de Barros, Gabriela Finoto Cavalheiro, Alexsandra Vila Maior de Souza, Giseli Karenina Traesel, Janete A Anselmo-Franci, Cândida Aparecida Leite Kassuya, Arielle Cristina Arena. Subacute toxicity assessment of diflubenzuron, an insect growth regulator, in adult male rats. Environmental toxicology. 2016 Apr; 31(4):407-14. doi: 10.1002/tox.22054. [PMID: 25266294]
  • Hassan Abdel-Gawad, Fathia Mahdy, Adly Hashad, Galal H Elgemeie. Fate of 14C-ethion insecticide in the presence of deltamethrin and dimilin pesticides in cotton seeds and oils, removal of ethion residues in oils, and bioavailability of its bound residues to experimental animals. Journal of agricultural and food chemistry. 2014 Dec; 62(51):12287-93. doi: 10.1021/jf504010h. [PMID: 25420216]
  • M M Parrilla Vázquez, P Parrilla Vázquez, M Martínez Galera, A Uclés Moreno. Comparison of two ionic liquid dispersive liquid-liquid microextraction approaches for the determination of benzoylurea insecticides in wastewater using liquid chromatography-quadrupole-linear ion trap-mass spectrometry: evaluation of green parameters. Journal of chromatography. A. 2014 Aug; 1356(?):1-9. doi: 10.1016/j.chroma.2014.06.032. [PMID: 24993054]
  • Wen-Kai Xia, Tian-Bo Ding, Jin-Zhi Niu, Chong-Yu Liao, Rui Zhong, Wen-Jia Yang, Bin Liu, Wei Dou, Jin-Jun Wang. Exposure to diflubenzuron results in an up-regulation of a chitin synthase 1 gene in citrus red mite, Panonychus citri (Acari: Tetranychidae). International journal of molecular sciences. 2014 Feb; 15(3):3711-28. doi: 10.3390/ijms15033711. [PMID: 24590130]
  • Pengqiang Du, Xingang Liu, Xiaojun Gu, Fengshou Dong, Jun Xu, Zhiqiang Kong, Yuanbo Li, Yongquan Zheng. Residue behaviour of six pesticides in button crimini during home canning. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2014; 31(6):1081-8. doi: 10.1080/19440049.2014.910314. [PMID: 24761834]
  • Valeria Guidi, Peter Lüthy, Mauro Tonolla. Comparison between diflubenzuron and a Bacillus thuringiensis israelensis- and Lysinibacillus sphaericus-based formulation for the control of mosquito larvae in urban catch basins in Switzerland. Journal of the American Mosquito Control Association. 2013 Jun; 29(2):138-45. doi: 10.2987/12-6301r.1. [PMID: 23923328]
  • K Ingenloff, R Garlapati, D Poché, M I Singh, J L Remmers, R M Poché. Feed-through insecticides for the control of the sand fly Phlebotomus argentipes. Medical and veterinary entomology. 2013 Mar; 27(1):10-8. doi: 10.1111/j.1365-2915.2012.00995.x. [PMID: 23278322]
  • Miguel A Ramos, Nadine R Sousa, Albina R Franco, Vítor Costa, Rui S Oliveira, Paula M L Castro. Effect of diflubenzuron on the development of Pinus pinaster seedlings inoculated with the ectomycorrhizal fungus Pisolithus tinctorius. Environmental science and pollution research international. 2013 Jan; 20(1):582-90. doi: 10.1007/s11356-012-1056-0. [PMID: 22782793]
  • Siddharth Tiwari, Paul J Clayson, Emily H Kuhns, Lukasz L Stelinski. Effects of buprofezin and diflubenzuron on various developmental stages of Asian citrus psyllid, Diaphorina citri. Pest management science. 2012 Oct; 68(10):1405-12. doi: 10.1002/ps.3323. [PMID: 22653617]
  • Mingrong Qian, Liqin Wu, Hu Zhang, Mingfei Xu, Rui Li, Xiangyun Wang, Caixia Sun. Determination of 16 insect growth regulators in edible Chinese traditional herbs by liquid chromatography electrospray tandem mass spectrometry. Analytical and bioanalytical chemistry. 2012 Mar; 402(7):2451-62. doi: 10.1007/s00216-011-5699-3. [PMID: 22271101]
  • F Erler, E Polat, H Demir, M Catal, G Tuna. Control of mushroom sciarid fly Lycoriella ingenua populations with insect growth regulators applied by soil drench. Journal of economic entomology. 2011 Jun; 104(3):839-44. doi: 10.1603/ec10292. [PMID: 21735902]
  • Mario Baldessari, Federica Trona, Gino Angeli, Claudio Ioriatti. Effectiveness of five insecticides for the control of adults and young stages of Cacopsylla melanoneura (Förster) (Hemiptera: Psyllidae) in a semi-field trial. Pest management science. 2010 Mar; 66(3):308-12. doi: 10.1002/ps.1876. [PMID: 19937976]
  • Chun-Xiang Zeng, Jin-Jun Wang. Influence of exposure to imidacloprid on survivorship, reproduction and vitellin content of the carmine spider mite, Tetranychus cinnabarinus. Journal of insect science (Online). 2010; 10(?):20. doi: 10.1673/031.010.2001. [PMID: 20578884]
  • Raymond A Cloyd, Nicholas R Timmons, Jessica M Goebel, Kenneth E Kemp. Effect of pesticides on adult rove beetle Atheta coriaria (Coleoptera: Staphylinidae) survival in growing medium. Journal of economic entomology. 2009 Oct; 102(5):1750-8. doi: 10.1603/029.102.0504. [PMID: 19886438]
  • Yuanmu Fan, Shaotang Huang, Xuejun Yu, Xiaojun Gu, Yajun Qiu, Shubing Chen, Keteng Fang, Jun Chen. [Determination of diflubenzuron and triflumuron residues in greasy wool by accelerated solvent extraction technique and high performance liquid chromatography]. Se pu = Chinese journal of chromatography. 2009 Jul; 27(4):463-6. doi: . [PMID: 19938504]
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  • Douglas H Ross, Charles Heird, John W Byrd, Vivienne Beauchemin, Wendy Kiess. Safety of elevated dosages of a 0.24\% diflubenzuron pellet administered orally to horses. Veterinary therapeutics : research in applied veterinary medicine. 2007; 8(1):61-76. doi: . [PMID: 17447226]
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