Ethion (BioDeep_00000002425)

 

Secondary id: BioDeep_00001867607

human metabolite blood metabolite


代谢物信息卡片


O,O-diethyl [({[diethoxy(sulfanylidene)-λ⁵-phosphanyl]sulfanyl}methyl)sulfanyl]phosphonothioate

化学式: C9H22O4P2S4 (383.9876152)
中文名称: 乙硫磷标准溶液
谱图信息: 最多检出来源 Mentha canadensis(plant) 85.71%

分子结构信息

SMILES: CCOP(=S)(OCC)SCSP(=S)(OCC)OCC
InChI: InChI=1S/C9H22O4P2S4/c1-5-10-14(16,11-6-2)18-9-19-15(17,12-7-3)13-8-4/h5-9H2,1-4H3

描述信息

CONFIDENCE standard compound; INTERNAL_ID 521; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10307; ORIGINAL_PRECURSOR_SCAN_NO 10302
CONFIDENCE standard compound; INTERNAL_ID 521; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10202; ORIGINAL_PRECURSOR_SCAN_NO 10197
CONFIDENCE standard compound; INTERNAL_ID 521; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10253; ORIGINAL_PRECURSOR_SCAN_NO 10251
CONFIDENCE standard compound; INTERNAL_ID 521; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10332; ORIGINAL_PRECURSOR_SCAN_NO 10329
CONFIDENCE standard compound; INTERNAL_ID 521; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10267; ORIGINAL_PRECURSOR_SCAN_NO 10265
CONFIDENCE standard compound; INTERNAL_ID 521; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10311; ORIGINAL_PRECURSOR_SCAN_NO 10309
INTERNAL_ID 521; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; CONFIDENCE standard compound; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10311; ORIGINAL_PRECURSOR_SCAN_NO 10309
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
CONFIDENCE standard compound; INTERNAL_ID 2607
CONFIDENCE standard compound; INTERNAL_ID 8477
CONFIDENCE standard compound; INTERNAL_ID 4027
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals

同义名列表

14 个代谢物同义名

O,O-diethyl [({[diethoxy(sulfanylidene)-λ⁵-phosphanyl]sulfanyl}methyl)sulfanyl]phosphonothioate; O,O-diethyl ({[diethoxy(sulfanylidene)-λ⁵-phosphanyl]sulfanyl}methyl)sulfanylphosphonothioate; O,O,O,o-tetraethyl S,s-methanediyl bis(dithiophosphoric acid); O,O,O,o-tetraethyl S,s-methylenebis(phosphorodithioic acid); O,O,O,o-tetraethyl S,s-methylenebis(phosphorodithioate); O,O,O,o-tetraethyl S,s-methanediyl bis(dithiophosphate); S,S-methylene bis(O,O-diethyl phosphorodithioic acid); S,S-methylene bis(O,O-diethyl phosphorodithioate); Bis(S-(diethoxyphosphinothioyl)mercapto)methane; Niagara 1240; Diethion; Ethopaz; Nialate; ethion



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sahar Delkash-Roudsari, Ana M Chicas-Mosier, Seyed Hossein Goldansaz, Khalil Talebi-Jahromi, Ahmad Ashouri, Charles I Abramson. Assessment of lethal and sublethal effects of imidacloprid, ethion, and glyphosate on aversive conditioning, motility, and lifespan in honey bees (Apis mellifera L.). Ecotoxicology and environmental safety. 2020 Nov; 204(?):111108. doi: 10.1016/j.ecoenv.2020.111108. [PMID: 32798750]
  • Hassan Abdel-Gawad, Fathia Mahdy, Adly Hashad, Galal H Elgemeie. Fate of 14C-ethion insecticide in the presence of deltamethrin and dimilin pesticides in cotton seeds and oils, removal of ethion residues in oils, and bioavailability of its bound residues to experimental animals. Journal of agricultural and food chemistry. 2014 Dec; 62(51):12287-93. doi: 10.1021/jf504010h. [PMID: 25420216]
  • Mahmoud M A Desouky, Hassan Abdel-Gawad, Bahira Hegazi. Distribution, fate and histopathological effects of ethion insecticide on selected organs of the crayfish, Procambarus clarkii. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2013 Feb; 52(?):42-52. doi: 10.1016/j.fct.2012.10.029. [PMID: 23127602]
  • G K Bhatti, J S Bhatti, R Kiran, R Sandhir. Alterations in Ca²⁺ homeostasis and oxidative damage induced by ethion in erythrocytes of Wistar rats: ameliorative effect of vitamin E. Environmental toxicology and pharmacology. 2011 May; 31(3):378-86. doi: 10.1016/j.etap.2011.01.004. [PMID: 21787708]
  • Pornpimol Kongtip, Sirinnapa Changfuang, Witaya Yoosook, Suttinun Chantanakul, Dusit Sujirarat. Ethion exposure and biological monitoring in vegetable farmers. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 2011 Mar; 94(3):286-94. doi: . [PMID: 21560835]
  • Hiroyuki Kojima, Fumihiro Sata, Shinji Takeuchi, Tatsuya Sueyoshi, Tadanori Nagai. Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays. Toxicology. 2011 Feb; 280(3):77-87. doi: 10.1016/j.tox.2010.11.008. [PMID: 21115097]
  • G K Bhatti, J S Bhatti, R Kiran, R Sandhir. Biochemical and morphological perturbations in rat erythrocytes exposed to ethion: protective effect of vitamin E. Cellular and molecular biology (Noisy-le-Grand, France). 2011 Feb; 57(1):70-9. doi: . [PMID: 21366965]
  • Jack Cochran. Evaluation of comprehensive two-dimensional gas chromatography - time-of-flight mass spectrometry for the determination of pesticides in tobacco. Journal of chromatography. A. 2008 Apr; 1186(1-2):202-10. doi: 10.1016/j.chroma.2008.01.043. [PMID: 18261736]
  • Aruna Dewan, Ashwin B Patel, Ramavati R Pal, Umesh J Jani, Vinu C Singel, Maulik D Panchal. Mass ethion poisoning with high mortality. Clinical toxicology (Philadelphia, Pa.). 2008 Jan; 46(1):85-8. doi: 10.1080/15563650701517251. [PMID: 17852169]
  • Huilong Xia, Xiangjuan Ma. Phytoremediation of ethion by water hyacinth (Eichhornia crassipes) from water. Bioresource technology. 2006 May; 97(8):1050-4. doi: 10.1016/j.biortech.2005.04.039. [PMID: 15982870]
  • Ihsan Ergün, M Cenk Akbostanci, Başol Canbakan, Bilge Koçer, Arzu Ensari, Gökhan Nergizoglu, Kenan Keven. Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005 Jul; 46(1):e11-4. doi: 10.1053/j.ajkd.2005.03.009. [PMID: 15983949]
  • D B Fragoso, R N C Guedes, R N C Guedes, M C Picanço, L Zambolim. Insecticide use and organophosphate resistance in the coffee leaf miner Leucoptera coffeella (Lepidoptera: Lyonetiidae). Bulletin of entomological research. 2002 Jun; 92(3):203-12. doi: 10.1079/ber2002156. [PMID: 12088537]
  • R D Mosha. Tissue distribution and urinary excretion of 14C-ethion in goats. Pharmacology & toxicology. 1991 Jul; 69(1):34-7. doi: 10.1111/j.1600-0773.1991.tb00405.x. [PMID: 1946189]
  • R D Mosha, N Gyrd-Hansen, P Nielsen. Fate of ethion in goats after intravenous, oral and dermal administration. Pharmacology & toxicology. 1990 Sep; 67(3):246-51. doi: 10.1111/j.1600-0773.1990.tb00822.x. [PMID: 2255681]
  • R D Mosha, N Gyrd-Hansen, P Nielsen. Distribution and elimination of 14C-ethion in laying hens and eggs after oral exposure. Bulletin of environmental contamination and toxicology. 1990 Sep; 45(3):375-81. doi: 10.1007/bf01701160. [PMID: 2257332]
  • R D Mosha, N Gyrd-Hansen. Toxicity of ethion in goats. Veterinary and human toxicology. 1990 Feb; 32(1):6-8. doi: . [PMID: 2301152]