temephos (BioDeep_00000002313)

 

Secondary id: BioDeep_00000404007

human metabolite blood metabolite


代谢物信息卡片


O-4-[(4-{[dimethoxy(sulfanylidene)-λ⁵-phosphanyl]oxy}phenyl)sulfanyl]phenyl O,O-dimethyl phosphorothioate

化学式: C16H20O6P2S3 (465.989724)
中文名称: 甲醇中双硫磷溶液
谱图信息: 最多检出来源 Homo sapiens(blood) 66.67%

分子结构信息

SMILES: COP(=S)(OC)OC1=CC=C(C=C1)SC2=CC=C(C=C2)OP(=S)(OC)OC
InChI: InChI=1S/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3

描述信息

D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals

同义名列表

25 个代谢物同义名

O-4-[(4-{[dimethoxy(sulfanylidene)-λ⁵-phosphanyl]oxy}phenyl)sulfanyl]phenyl O,O-dimethyl phosphorothioate; [4-(4-Dimethoxyphosphinothioyloxyphenyl)sulphanylphenoxy]-dimethoxy-sulphanylidene-$l^{5}-phosphane; O,O,O,o-tetramethyl O,o-(sulphanediyldibenzene-4,1-diyl) bis(thiophosphoric acid); O,O,O,o-tetramethyl O,o-(sulfanediyldibenzene-4,1-diyl) bis(thiophosphoric acid); O,O,O,o-tetramethyl O,o-(sulphanediyldi-4,1-phenylene) bis(phosphorothioic acid); O,O,O,o-tetramethyl O,o-(sulfanediyldi-4,1-phenylene) bis(phosphorothioic acid); O,O,O,o-tetramethyl O,o-(sulphanediyldi-4,1-phenylene) bis(phosphorothioate); O,O,O,o-tetramethyl O,o-(sulphanediyldibenzene-4,1-diyl) bis(thiophosphate); O,O,O,o-tetramethyl O,o-(sulfanediyldi-4,1-phenylene) bis(phosphorothioate); O,O,O,o-tetramethyl O,o-(sulfanediyldibenzene-4,1-diyl) bis(thiophosphate); Phosphorothioic acid, O,o-(thiodi-4,1-phenylene) O,O,o,o-tetramethyl ester; Phosphorothioate, O,o-(thiodi-4,1-phenylene) O,O,o,o-tetramethyl ester; O,O-(thiodi-p-phenylene) O,O,o,o-tetramethyl bis(phosphorothioic acid); O,O,O,o-tetramethyl O,o-thiodi-p-phenylene bis(phosphorothioic acid); O,O-(thiodi-p-phenylene) O,O,o,o-tetramethyl bis(phosphorothioate); O,O-(thiodi-4,1-phenylene) bis(O,O-dimethyl phosphorothioic acid); O,O,O,o-tetramethyl O,o-thiodi-p-phenylene diphosphorothioic acid; O,O,O,o-tetramethyl O,o-thiodi-p-phenylene bis(phosphorothioate); O,O,O,o-tetramethyl O,o-thiodi-p-phenylene diphosphorothioate; O,O-(thiodi-4,1-phenylene) bis(O,O-dimethyl phosphorothioate); Abic acid; temephos; Temefos; Abate; Difos



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Oluwatobiloba F Da-Silva, Adedoyin R Adelowo, Adesina A Babalola, Cynthia N Ikeji, Olatunde Owoeye, Joao B T Rocha, Isaac A Adedara, Ebenezer O Farombi. Diphenyl Diselenide Through Reduction of Inflammation, Oxidative Injury and Caspase-3 Activation Abates Doxorubicin-Induced Neurotoxicity in Rats. Neurochemical research. 2024 Jan; ?(?):. doi: 10.1007/s11064-023-04098-1. [PMID: 38267690]
  • Tanapoom Moungthipmalai, Cheepchanok Puwanard, Jirapon Aungtikun, Sirawut Sittichok, Mayura Soonwera. Ovicidal toxicity of plant essential oils and their major constituents against two mosquito vectors and their non-target aquatic predators. Scientific reports. 2023 Feb; 13(1):2119. doi: 10.1038/s41598-023-29421-2. [PMID: 36746998]
  • Merdya Muhammed, Sisay Dugassa, Merga Belina, Sarah Zohdy, Seth R Irish, Araya Gebresilassie. Insecticidal effects of some selected plant extracts against Anopheles stephensi (Culicidae: Diptera). Malaria journal. 2022 Oct; 21(1):295. doi: 10.1186/s12936-022-04320-5. [PMID: 36271447]
  • Juan Pablo Martínez-Mercado, Adolfo Sierra-Santoyo, Francisco Alberto Verdín-Betancourt, Aurora Elizabeth Rojas-García, Betzabet Quintanilla-Vega. Temephos, an organophosphate larvicide for residential use: a review of its toxicity. Critical reviews in toxicology. 2022 02; 52(2):113-124. doi: 10.1080/10408444.2022.2065967. [PMID: 35608007]
  • Josiane Somariva Prophiro, Mario Antonio Navarro da Silva, Joice Guilherme de Oliveira, Paula Fassicolo Variza, Alessandra B de Lemos, Harry Luiz Pilz-Júnior, Onilda Santos da Silva. Change in susceptibility response of Aedes aegypti (Diptera: Culicidae) to organophosphate insecticide and Copaifera oleoresin. Acta tropica. 2021 Sep; 221(?):106014. doi: 10.1016/j.actatropica.2021.106014. [PMID: 34146537]
  • Bruno Gomes, Huarlen Ogélio, Fabiane Brant, Camila Jesus Pereira-Pinto, Michael J Workman, Monique Costa, José Bento Pereira Lima, Ademir Jesus Martins, Marcelo Ramalho-Ortigao, Ravi Durvasula, Ivy Hurwitz, Mariana Rocha David, Fernando Ariel Genta. High larvicidal efficacy of yeast-encapsulated orange oil against Aedes aegypti strains from Brazil. Parasites & vectors. 2021 May; 14(1):272. doi: 10.1186/s13071-021-04733-2. [PMID: 34022935]
  • Anuluck Junkum, Jitrawadee Intirach, Arpaporn Chansang, Danita Champakaew, Udom Chaithong, Atchariya Jitpakdi, Doungrat Riyong, Pradya Somboon, Benjawan Pitasawat. Enhancement of Temephos and Deltamethrin Toxicity by Petroselinum crispum Oil and its Main Constituents Against Aedes aegypti (Diptera: Culicidae). Journal of medical entomology. 2021 05; 58(3):1298-1315. doi: 10.1093/jme/tjab008. [PMID: 33570125]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Francisco Alberto Verdín-Betancourt, Mario Figueroa, Alicia Guadalupe Soto-Ramos, Ma de Lourdes López-González, Gilberto Castañeda-Hernández, Yael Yvette Bernal-Hernández, Aurora Elizabeth Rojas-García, Adolfo Sierra-Santoyo. Toxicokinetics of temephos after oral administration to adult male rats. Archives of toxicology. 2021 03; 95(3):935-947. doi: 10.1007/s00204-021-02975-8. [PMID: 33471133]
  • Christos I Rumbos, Christos G Athanassiou. Assessment of selected larvicides for the control of Culex pipiens biotype pipiens and Culex pipiens biotype molestus under laboratory and semi-field conditions. Pest management science. 2020 Nov; 76(11):3568-3576. doi: 10.1002/ps.5847. [PMID: 32533802]
  • Perumal Vivekanandhan, Ayyakkannu Usha-Raja-Nanthini, Gurusamy Valli, Muthugoundar Subramanian Shivakumar. Comparative efficacy of Eucalyptus globulus (Labill) hydrodistilled essential oil and temephos as mosquito larvicide. Natural product research. 2020 Sep; 34(18):2626-2629. doi: 10.1080/14786419.2018.1547290. [PMID: 30623679]
  • Manop Saeung, Ratchadawan Ngoen-Klan, Kanutcharee Thanispong, Vithee Muenworn, Michael J Bangs, Theeraphap Chareonviriyaphap. Susceptibility of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) to Temephos in Thailand and Surrounding Countries. Journal of medical entomology. 2020 07; 57(4):1207-1220. doi: 10.1093/jme/tjaa035. [PMID: 32159772]
  • Xiaoyan Fan, Haruna Matsumoto, Yue Wang, Yang Hu, Yufei Liu, Hongda Fang, Bartosz Nitkiewicz, Sharon Yu Ling Lau, Qiangwei Wang, Hua Fang, Mengcen Wang. Microenvironmental Interplay Predominated by Beneficial Aspergillus Abates Fungal Pathogen Incidence in Paddy Environment. Environmental science & technology. 2019 Nov; 53(22):13042-13052. doi: 10.1021/acs.est.9b04616. [PMID: 31631659]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Weijia Zheng, Jeong-Min Choi, A M Abd El-Aty, Kyung-Hee Yoo, Da-Hee Park, Seong-Kwan Kim, Young-Sun Kang, Ahmet Hacımüftüoğlu, Jing Wang, Jae-Han Shim, Ho-Chul Shin. Simultaneous determination of spinosad, temephos, and piperonyl butoxide in animal-derived foods using LC-MS/MS. Biomedical chromatography : BMC. 2019 Jun; 33(6):e4493. doi: 10.1002/bmc.4493. [PMID: 30663083]
  • Lijiao Geng, Tao Zhang, Wei Liu, Yong Chen. Inhibition of miR-128 Abates Aβ-Mediated Cytotoxicity by Targeting PPAR-γ via NF-κB Inactivation in Primary Mouse Cortical Neurons and Neuro2a Cells. Yonsei medical journal. 2018 Nov; 59(9):1096-1106. doi: 10.3349/ymj.2018.59.9.1096. [PMID: 30328325]
  • Soon-Il Kim, Young-Joon Ahn. Larvicidal activity of lignans and alkaloid identified in Zanthoxylum piperitum bark toward insecticide-susceptible and wild Culex pipiens pallens and Aedes aegypti. Parasites & vectors. 2017 May; 10(1):221. doi: 10.1186/s13071-017-2154-0. [PMID: 28472971]
  • Prabhakaran Vasantha-Srinivasan, Sengottayan Senthil-Nathan, Athirstam Ponsankar, Annamalai Thanigaivel, Edward-Sam Edwin, Selvaraj Selin-Rani, Muthiah Chellappandian, Venkatraman Pradeepa, Jalasteen Lija-Escaline, Kandaswamy Kalaivani, Wayne B Hunter, Veeramuthu Duraipandiyan, Naif Abdullah Al-Dhabi. Comparative analysis of mosquito (Diptera: Culicidae: Aedes aegypti Liston) responses to the insecticide Temephos and plant derived essential oil derived from Piper betle L. Ecotoxicology and environmental safety. 2017 May; 139(?):439-446. doi: 10.1016/j.ecoenv.2017.01.026. [PMID: 28213320]
  • Mahboobeh Sharifi, Mohammad Ghadamyari, Khodayar Gholivand, Ali Asghar Ebrahimi Valmoozi, Reza H Sajedi. Characterization of acetylcholinesterase from elm left beetle, Xanthogaleruca luteola and QSAR of temephos derivatives against its activity. Pesticide biochemistry and physiology. 2017 Mar; 136(?):12-22. doi: 10.1016/j.pestbp.2016.08.010. [PMID: 28187825]
  • Linda Grigoraki, Jacques Lagnel, Ilias Kioulos, Anastasia Kampouraki, Evangelia Morou, Pierrick Labbé, Mylene Weill, John Vontas. Transcriptome Profiling and Genetic Study Reveal Amplified Carboxylesterase Genes Implicated in Temephos Resistance, in the Asian Tiger Mosquito Aedes albopictus. PLoS neglected tropical diseases. 2015 May; 9(5):e0003771. doi: 10.1371/journal.pntd.0003771. [PMID: 26000638]
  • Rajendra Maharaj, Vinesh Maharaj, Neil R Crouch, Niresh Bhagwandin, Peter I Folb, Pamisha Pillay, Reshma Gayaram. Screening of selected ethnomedicinal plants from South Africa for larvicidal activity against the mosquito Anopheles arabiensis. Malaria journal. 2012 Sep; 11(?):320. doi: 10.1186/1475-2875-11-320. [PMID: 22963538]
  • Edilson Alves Dos Santos, Cenira M de Carvalho, Ana L S Costa, Adilva S Conceição, Flávia de B Prado Moura, Antônio Euzébio Goulart Santana. Bioactivity Evaluation of Plant Extracts Used in Indigenous Medicine against the Snail, Biomphalaria glabrata, and the Larvae of Aedes aegypti. Evidence-based complementary and alternative medicine : eCAM. 2012; 2012(?):846583. doi: 10.1155/2012/846583. [PMID: 22194773]
  • Satyender Singh, Vivek Kumar, Sachin Thakur, Basu Dev Banerjee, Sudhir Chandna, Rajender Singh Rautela, Shyam Sunder Grover, Devendra Singh Rawat, Syed Tazeen Pasha, Sudhir Kumar Jain, Rattan Lal Ichhpujani, Arvind Rai. DNA damage and cholinesterase activity in occupational workers exposed to pesticides. Environmental toxicology and pharmacology. 2011 Mar; 31(2):278-85. doi: 10.1016/j.etap.2010.11.005. [PMID: 21787695]
  • Adriano R Paula, Aline T Carolino, Cátia O Paula, Richard I Samuels. The combination of the entomopathogenic fungus Metarhizium anisopliae with the insecticide Imidacloprid increases virulence against the dengue vector Aedes aegypti (Diptera: Culicidae). Parasites & vectors. 2011 Jan; 4(?):8. doi: 10.1186/1756-3305-4-8. [PMID: 21266078]
  • Haribalan Perumalsamy, Kyu Sik Chang, Chan Park, Young-Joon Ahn. Larvicidal activity of Asarum heterotropoides root constituents against insecticide-susceptible and -resistant Culex pipiens pallens and Aedes aegypti and Ochlerotatus togoi. Journal of agricultural and food chemistry. 2010 Sep; 58(18):10001-6. doi: 10.1021/jf102193k. [PMID: 20806890]
  • Patrícia V Oliveira, Jesú C Ferreira, Fabyanne S Moura, Gerson S Lima, Fernando M de Oliveira, Patrícia Emanuella S Oliveira, Lucia M Conserva, Ana Maria Giulietti, Rosangela P Lyra Lemos. Larvicidal activity of 94 extracts from ten plant species of northeastern of Brazil against Aedes aegypti L. (Diptera: Culicidae). Parasitology research. 2010 Jul; 107(2):403-7. doi: 10.1007/s00436-010-1880-4. [PMID: 20449754]
  • Lalit Mohan, Preeti Sharma, C N Srivastava. Combination larvicidal action of Solanum xanthocarpum extract and certain synthetic insecticides against filarial vector, Culex quinquefasciatus (SAY). The Southeast Asian journal of tropical medicine and public health. 2010 Mar; 41(2):311-9. doi: . [PMID: 20578513]
  • Waldemir Pereira Lima, Francisco Chiaravalloti Neto, Maria de Lourdes da Graça Macoris, Débora Aparecida Pires de Campos Zuccari, Margareth Regina Dibo. [Establishment of the feeding methodology of Aedes aegypti (Diptera-Culicidae) in Swiss mice and evaluation of the toxicity and residual effect of essential oil from Tagetes minuta L (Asteraceae), in populations of Aedes aegypti]. Revista da Sociedade Brasileira de Medicina Tropical. 2009 Nov; 42(6):638-41. doi: 10.1590/s0037-86822009000600005. [PMID: 20209346]
  • Haribalan Perumalsamy, Nam-Jin Kim, Young-Joon Ahn. Larvicidal activity of compounds isolated from Asarum heterotropoides against Culex pipiens pallens, Aedes aegypti, and Ochlerotatus togoi (Diptera: Culicidae). Journal of medical entomology. 2009 Nov; 46(6):1420-3. doi: 10.1603/033.046.0624. [PMID: 19960690]
  • Mathieu Tilquin, Margot Paris, Stéphane Reynaud, Laurence Despres, Patrick Ravanel, Roberto A Geremia, Jérôme Gury. Long lasting persistence of Bacillus thuringiensis Subsp. israelensis (Bti) in mosquito natural habitats. PloS one. 2008; 3(10):e3432. doi: 10.1371/journal.pone.0003432. [PMID: 18941501]
  • Daruna Champakaew, Wej Choochote, Yanee Pongpaibul, Udom Chaithong, Atchariya Jitpakdi, Benjawan Tuetun, Benjawan Pitasawat. Larvicidal efficacy and biological stability of a botanical natural product, zedoary oil-impregnated sand granules, against Aedes aegypti (Diptera, Culicidae). Parasitology research. 2007 Mar; 100(4):729-37. doi: 10.1007/s00436-006-0350-5. [PMID: 17096143]
  • Cheryl Lans, Nancy Turner, Tonya Khan, Gerhard Brauer, Willi Boepple. Ethnoveterinary medicines used for ruminants in British Columbia, Canada. Journal of ethnobiology and ethnomedicine. 2007 Feb; 3(?):11. doi: 10.1186/1746-4269-3-11. [PMID: 17324258]
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