2-Hydroxybutyric acid (BioDeep_00000229680)

Main id: BioDeep_00000265237

 

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


DL-alpha-Hydroxybutyric acid

化学式: C4H8O3 (104.0473)
中文名称: S-2-羟基丁酸, 2-羟基丁酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(C(=O)O)O
InChI: InChI=1S/C4H8O3/c1-2-3(5)4(6)7/h3,5H,2H2,1H3,(H,6,7)

描述信息

(S)-2-Hydroxybutanoic acid is the S-enantiomer of?2-Hydroxybutanoic acid. 2-Hydroxybutanoic acid, a coproduct of protein metabolism, is an insulin resistance (IR) biomarker[1].

同义名列表

5 个代谢物同义名

DL-alpha-Hydroxybutyric acid; (S)-2-Hydroxybutyric acid; 2-Hydroxybutyric acid; (S)-2-Hydroxybutanoic acid; 2-Hydroxybutyric acid



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ALB, BDH2, FDPS, LDHA, LRRK2
Peripheral membrane protein 1 LRRK2
Endoplasmic reticulum membrane 3 FADS2, LRRK2, SSR2
Nucleus 4 ALB, DLD, H4C9, LDHA
cytosol 7 ALB, BDH2, FDPS, HBD, LDHA, LRRK2, MB
dendrite 1 LRRK2
mitochondrial membrane 1 LRRK2
phagocytic vesicle 1 LRRK2
trans-Golgi network 1 LRRK2
centrosome 1 ALB
nucleoplasm 2 FDPS, H4C9
Cell membrane 1 FCGR1A
Cell projection, axon 1 LRRK2
Early endosome membrane 1 FCGR1A
Multi-pass membrane protein 1 FADS2
Golgi apparatus membrane 1 LRRK2
Synapse 1 ALDH5A1
cell surface 1 C3
glutamatergic synapse 1 LRRK2
Golgi apparatus 2 ALB, LRRK2
Golgi membrane 2 INS, LRRK2
growth cone 1 LRRK2
mitochondrial inner membrane 2 LDHD, LRRK2
neuronal cell body 1 LRRK2
postsynapse 1 LRRK2
Lysosome 1 LRRK2
acrosomal vesicle 1 DLD
endosome 1 LRRK2
plasma membrane 5 C3, FADS2, FCGR1A, GCG, LRRK2
synaptic vesicle membrane 1 LRRK2
terminal bouton 1 LRRK2
Membrane 7 FADS2, FCGR1A, FDPS, H4C9, HBD, LDHA, SSR2
axon 1 LRRK2
extracellular exosome 7 ALB, BDH2, C3, H4C9, LDHA, LRRK2, MB
endoplasmic reticulum 3 ALB, LRRK2, SSR2
extracellular space 7 ALB, C3, COL2A1, CXCL8, GCG, INS, LRRK2
mitochondrion 6 ALDH5A1, DLD, HMGCS2, LDHA, LDHD, LRRK2
protein-containing complex 3 ALB, C3, H4C9
intracellular membrane-bounded organelle 1 LRRK2
Single-pass type I membrane protein 2 FCGR1A, SSR2
Secreted 6 ALB, C3, COL2A1, CXCL8, GCG, INS
extracellular region 7 ALB, C3, COL2A1, CXCL8, GCG, H4C9, INS
Mitochondrion outer membrane 1 LRRK2
mitochondrial outer membrane 1 LRRK2
Mitochondrion matrix 1 DLD
mitochondrial matrix 5 ALDH5A1, DLD, FDPS, HMGCS2, LRRK2
anchoring junction 1 ALB
motile cilium 1 DLD
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 LRRK2
external side of plasma membrane 1 FCGR1A
Secreted, extracellular space, extracellular matrix 1 COL2A1
perikaryon 1 LRRK2
cytoplasmic vesicle 1 LRRK2
Wnt signalosome 1 LRRK2
sarcoplasm 1 MB
Golgi-associated vesicle 1 LRRK2
Cytoplasm, cytoskeleton 1 LRRK2
Peroxisome 1 FDPS
basement membrane 1 COL2A1
collagen trimer 1 COL2A1
collagen-containing extracellular matrix 1 COL2A1
dendrite cytoplasm 1 LRRK2
neuron projection 1 LRRK2
ciliary basal body 1 ALB
cytoskeleton 1 LRRK2
centriole 1 ALB
Cytoplasmic vesicle, secretory vesicle, acrosome 1 DLD
spindle pole 1 ALB
chromosome, telomeric region 1 H4C9
blood microparticle 3 ALB, C3, HBD
Cell projection, cilium, flagellum 1 DLD
endosome lumen 1 INS
microvillus 1 LRRK2
Cell projection, dendrite 1 LRRK2
secretory granule lumen 3 C3, GCG, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 5 ALB, C3, COL2A1, GCG, INS
platelet alpha granule lumen 1 ALB
pyruvate dehydrogenase complex 1 DLD
transport vesicle 1 INS
azurophil granule lumen 1 C3
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
endoplasmic reticulum exit site 1 LRRK2
oxoglutarate dehydrogenase complex 1 DLD
clathrin-coated endocytic vesicle membrane 1 FCGR1A
ribonucleoprotein complex 1 LRRK2
nucleosome 1 H4C9
Cytoplasmic vesicle, phagosome 1 LRRK2
presynaptic cytosol 1 LRRK2
oxidoreductase complex 1 LDHA
hemoglobin complex 1 HBD
haptoglobin-hemoglobin complex 1 HBD
[Glucagon-like peptide 1]: Secreted 1 GCG
Cytoplasm, sarcoplasm 1 MB
collagen type II trimer 1 COL2A1
collagen type XI trimer 1 COL2A1
multivesicular body, internal vesicle 1 LRRK2
Autolysosome 1 LRRK2
CENP-A containing nucleosome 1 H4C9
acetyltransferase complex 1 DLD
acrosomal matrix 1 DLD
branched-chain alpha-ketoacid dehydrogenase complex 1 DLD
oxoadipate dehydrogenase complex 1 DLD
cytoplasmic side of mitochondrial outer membrane 1 LRRK2
ciliary transition fiber 1 ALB
amphisome 1 LRRK2
caveola neck 1 LRRK2


文献列表

  • Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]
  • T Fukushima. [Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 1975 Jul; 71(5):457-62. doi: . [PMID: 280]