P-Toluenesulfonamide (BioDeep_00000002182)

   

human metabolite blood metabolite


代谢物信息卡片


4-Toluenesulfonamide, mercury (+2) salt (2:1)

化学式: C7H9NO2S (171.0353974)
中文名称: 对甲苯磺酰胺
谱图信息: 最多检出来源 Anoectochilus roxburghii(viridiplantae) 0.8%

分子结构信息

SMILES: CC1=CC=C(C=C1)S(=O)(=O)N
InChI: InChI=1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)

描述信息

CONFIDENCE standard compound; INTERNAL_ID 926; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4179; ORIGINAL_PRECURSOR_SCAN_NO 4178
CONFIDENCE standard compound; INTERNAL_ID 926; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4160; ORIGINAL_PRECURSOR_SCAN_NO 4155
CONFIDENCE standard compound; INTERNAL_ID 926; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4177; ORIGINAL_PRECURSOR_SCAN_NO 4175
CONFIDENCE standard compound; INTERNAL_ID 926; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4145; ORIGINAL_PRECURSOR_SCAN_NO 4142
CONFIDENCE standard compound; INTERNAL_ID 926; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4171; ORIGINAL_PRECURSOR_SCAN_NO 4169
CONFIDENCE standard compound; INTERNAL_ID 926; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4164; ORIGINAL_PRECURSOR_SCAN_NO 4159
C274 - Antineoplastic Agent > C129839 - Apoptotic Pathway-targeting Antineoplastic Agent
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3618
CONFIDENCE standard compound; INTERNAL_ID 4185
CONFIDENCE standard compound; INTERNAL_ID 2869
CONFIDENCE standard compound; INTERNAL_ID 8805
COVID info from PDB, Protein Data Bank
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

22 个代谢物同义名

4-Toluenesulfonamide, mercury (+2) salt (2:1); 4-Toluenesulfonamide, mercury (+2) salt (1:1); 4-Toluenesulfonamide, monopotassium salt; 4-Toluenesulfonamide, monosodium salt; 4-Toluenesulfonamide, 6-(14)C-labeled; 4-Toluenesulfonamide, monosilver salt; 4-Toluenesulfonamide hydrochloride; 4-methylbenzene-1-sulfonamide; 4-Methylbenzenesulphonamide; 4-methylbenzenesulfonamide; Para-toluenesulphonamide; Para-toluenesulfonamide; Toluene-4-sulphonamide; 4-Toluenesulfonylamide; p-Toluenesulphonamide; 4-Toluenesulphonamide; 4-Toluenesulfonamide; P-TOLUENESULFONAMIDE; p-Tolylsulphonamide; p-Tolylsulfonamide; p-Tosylamide; Tosylamide



数据库引用编号

45 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jui-Ling Hsu, Wohn-Jenn Leu, Nan-Shan Zhong, Jih-Hwa Guh. Autophagic Activation and Decrease of Plasma Membrane Cholesterol Contribute to Anticancer Activities in Non-Small Cell Lung Cancer. Molecules (Basel, Switzerland). 2021 Oct; 26(19):. doi: 10.3390/molecules26195967. [PMID: 34641511]
  • Ramazan Demirdağ, Veysel Çomaklı, Murat Şentürk, Deniz Ekinci, Ö İrfan Küfrevioğlu, Claudiu T Supuran. Purification and characterization of carbonic anhydrase from sheep kidney and effects of sulfonamides on enzyme activity. Bioorganic & medicinal chemistry. 2013 Mar; 21(6):1522-5. doi: 10.1016/j.bmc.2012.08.018. [PMID: 22974493]
  • Raffaella Meffe, Claus Kohfahl, Ekkehard Holzbecher, Gudrun Massmann, Doreen Richter, Uwe Dünnbier, Asaf Pekdeger. Modelling the removal of p-TSA (para-toluenesulfonamide) during rapid sand filtration used for drinking water treatment. Water research. 2010 Jan; 44(1):205-13. doi: 10.1016/j.watres.2009.08.046. [PMID: 19766287]
  • Doreen Richter, Gudrun Massmann, Thomas Taute, Uwe Duennbier. Investigation of the fate of sulfonamides downgradient of a decommissioned sewage farm near Berlin, Germany. Journal of contaminant hydrology. 2009 May; 106(3-4):183-94. doi: 10.1016/j.jconhyd.2009.03.001. [PMID: 19371963]
  • Mika Hilvo, Anna Maria Salzano, Alessio Innocenti, Markku S Kulomaa, Andrea Scozzafava, Andrea Scaloni, Seppo Parkkila, Claudiu T Supuran. Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. Journal of medicinal chemistry. 2009 Feb; 52(3):646-54. doi: 10.1021/jm801267c. [PMID: 19193158]
  • Doreen Richter, Gudrun Massmann, Uwe Dünnbier. Behaviour and biodegradation of sulfonamides (p-TSA, o-TSA, BSA) during drinking water treatment. Chemosphere. 2008 Apr; 71(8):1574-81. doi: 10.1016/j.chemosphere.2007.11.026. [PMID: 18179813]
  • Mary A Soliman, Joel A Pedersen, Heesu Park, Angelica Castaneda-Jimenez, Michael K Stenstrom, I H Mel Suffet. Human pharmaceuticals, antioxidants, and plasticizers in wastewater treatment plant and water reclamation plant effluents. Water environment research : a research publication of the Water Environment Federation. 2007 Feb; 79(2):156-67. doi: 10.2175/106143006x111961. [PMID: 17370841]
  • S B Levy. Allergenic ingredients in nail polishes. Contact dermatitis. 1998 May; 38(5):303. doi: 10.1111/j.1600-0536.1998.tb05761.x. [PMID: 9667464]
  • B M Hausen, M Milbrodt, W A Koenig. The allergens of nail polish. (I). Allergenic constituents of common nail polish and toluenesulfonamide-formaldehyde resin (TS-F-R). Contact dermatitis. 1995 Sep; 33(3):157-64. doi: 10.1111/j.1600-0536.1995.tb00537.x. [PMID: 8565455]
  • P Eggena, J D Barrett, C E Wiedman, M P Sambhi. Studies on renin activation in normal human plasma. Hypertension (Dallas, Tex. : 1979). 1979 Sep; 1(5):523-8. doi: 10.1161/01.hyp.1.5.523. [PMID: 94312]