BENSULFURON-METHYL (BioDeep_00000001899)
human metabolite blood metabolite
代谢物信息卡片
化学式: C16H18N4O7S (410.0896)
中文名称: 苄嘧磺隆
谱图信息:
最多检出来源 Homo sapiens(not specific) 37.5%
分子结构信息
SMILES: COC(=O)C1=CC=CC=C1CS(=O)(=O)NC(=O)NC1=NC(OC)=CC(OC)=N1
InChI: InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)
描述信息
同义名列表
43 个代谢物同义名
2-((((((4,6-Dimethoxy-2-pyrimidinyl)amino)carbonyl)amino)sulfonyl)methyl)benzoic acid methyl ester; Methyl 2-[[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulphonyl]methyl]benzoic acid; Methyl 2-[[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]methyl]benzoic acid; Methyl 2-[[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulphonyl]methyl]benzoate; Methyl 2-[[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]methyl]benzoate; methyl 2-[({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)methyl]benzoate; Methyl alpha-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulphamoyl]-O-toluic acid; Methyl alpha-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-O-toluic acid; Methyl alpha-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulphamoyl]-O-toluate; Methyl α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulphamoyl]-O-toluic acid; Methyl alpha-((4,6-dimethoxypyrimidin-2-yl)ureidosulphonyl)-O-toluic acid; Methyl a-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulphamoyl]-O-toluic acid; Methyl alpha-((4,6-dimethoxypyrimidin-2-yl)ureidosulfonyl)-O-toluic acid; Methyl alpha-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-O-toluate; Methyl a-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-O-toluic acid; Methyl α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-O-toluic acid; Methyl α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulphamoyl]-O-toluate; Methyl α-((4,6-dimethoxypyrimidin-2-yl)ureidosulphonyl)-O-toluic acid; Methyl a-((4,6-dimethoxypyrimidin-2-yl)ureidosulphonyl)-O-toluic acid; Methyl alpha-((4,6-dimethoxypyrimidin-2-yl)ureidosulphonyl)-O-toluate; Methyl a-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulphamoyl]-O-toluate; Methyl α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-O-toluate; Methyl α-((4,6-dimethoxypyrimidin-2-yl)ureidosulfonyl)-O-toluic acid; Methyl a-((4,6-dimethoxypyrimidin-2-yl)ureidosulfonyl)-O-toluic acid; Methyl a-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-O-toluate; Methyl alpha-((4,6-dimethoxypyrimidin-2-yl)ureidosulfonyl)-O-toluate; Methyl α-((4,6-dimethoxypyrimidin-2-yl)ureidosulphonyl)-O-toluate; Methyl a-((4,6-dimethoxypyrimidin-2-yl)ureidosulphonyl)-O-toluate; Methyl α-((4,6-dimethoxypyrimidin-2-yl)ureidosulfonyl)-O-toluate; Methyl a-((4,6-dimethoxypyrimidin-2-yl)ureidosulfonyl)-O-toluate; Methyl bensulfuron, lithium salt; Bensulfuron-methyl [ANSI, WSSA]; Bensulphuron methyl ester; bensulfuron-methyl (PH7); Bensulfuron methyl ester; Methyl bensulphuron; Bensulphuron methyl; Bensulphuron-methyl; Methyl bensulfuron; Bensulfuron methyl; BENSULFURON-METHYL; Londax; Bensulfuron-methyl
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:3017
- KEGG: C10937
- PubChem: 54960
- HMDB: HMDB0248961
- Metlin: METLIN68703
- ChEMBL: CHEMBL2313154
- chemspider: 49630
- CAS: 104466-83-3
- CAS: 83055-99-6
- PMhub: MS000001411
- PubChem: 13120
- PDB-CCD: 60G
- NIKKAJI: J195.901H
- KNApSAcK: 3017
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Wei Deng, Sai Yao, Yang Li, Hanqi Yin, Qian Yang, Shuzhong Yuan. An Asp376Glu substitution and P450s-involved metabolism endow resistance to ALS inhibitors in an Ammannia auriculata Willd. Population.
Pesticide biochemistry and physiology.
2024 May; 201(?):105911. doi:
10.1016/j.pestbp.2024.105911. [PMID: 38685231] - Chunran Zhou, Peijuan Miao, Qinyong Dong, Dong Li, Canping Pan. Multiomics Explore the Detoxification Mechanism of Nanoselenium and Melatonin on Bensulfuron Methyl in Wheat Plants.
Journal of agricultural and food chemistry.
2024 Feb; 72(8):3958-3972. doi:
10.1021/acs.jafc.3c08429. [PMID: 38363203] - Yating Guo, Xiaohui Xu, Jinbei Lin, Haiqing Li, Weikang Guo, Shuqing Wan, Zepeng Chen, Hanhong Xu, Fei Lin. The herbicide bensulfuron-methyl inhibits rice seedling development by blocking calcium ion flux in the OsCNGC12 channel.
The Plant journal : for cell and molecular biology.
2023 Aug; ?(?):. doi:
10.1111/tpj.16418. [PMID: 37574927] - Alex R Ceseski, Amar S Godar, Sara Ohadi, Kassim Al-Khatib. Target and nontarget mechanisms of AHAS inhibitor cross-resistance patterns in Cyperus difformis.
Pesticide biochemistry and physiology.
2023 Jun; 193(?):105444. doi:
10.1016/j.pestbp.2023.105444. [PMID: 37248013] - Yize Zou, Bochui Zhao, Shihan Cao, Yidi Guan, Liru Liu, Mingshan Ji. Mutation at the 197 site and P450-mediated metabolic resistance are involved in bensulfuron-methyl resistance in Sagittaria trifolia.
Plant science : an international journal of experimental plant biology.
2023 Apr; ?(?):111700. doi:
10.1016/j.plantsci.2023.111700. [PMID: 37028456] - Ying Du, Minlong Wang, Yan Chen, Yunyan Deng, Lulu Zhang, Tianlang Bai, Mingshan Ji. Occurrence and mechanism of target-site resistance to bensulfuron-methyl in Monochoria korsakowii from China.
Pesticide biochemistry and physiology.
2023 Apr; 191(?):105379. doi:
10.1016/j.pestbp.2023.105379. [PMID: 36963949] - Yize Zou, Shihan Cao, Bochui Zhao, Zhonghua Sun, Liru Liu, Mingshan Ji. Increase in glutathione S-transferase activity and antioxidant damage ability drive resistance to bensulfuron-methyl in Sagittaria trifolia.
Plant physiology and biochemistry : PPB.
2022 Nov; 190(?):240-247. doi:
10.1016/j.plaphy.2022.09.007. [PMID: 36148723] - Danh Duc Ha, Thị Oanh Nguyen. Application of Methylopila sp. DKT for Bensulfuron-methyl Degradation and Peanut Growth Promotion.
Current microbiology.
2020 Aug; 77(8):1466-1475. doi:
10.1007/s00284-020-01953-0. [PMID: 32219473] - Niña Gracel Dimaano, Takuya Yamaguchi, Kanade Fukunishi, Tohru Tominaga, Satoshi Iwakami. Functional characterization of cytochrome P450 CYP81A subfamily to disclose the pattern of cross-resistance in Echinochloa phyllopogon.
Plant molecular biology.
2020 Mar; 102(4-5):403-416. doi:
10.1007/s11103-019-00954-3. [PMID: 31898147] - Qianxin Huang, Jinyang Lv, Yanyan Sun, Hongmei Wang, Yuan Guo, Gaoping Qu, Shengwu Hu. Inheritance and Molecular Characterization of a Novel Mutated AHAS Gene Responsible for the Resistance of AHAS-Inhibiting Herbicides in Rapeseed (Brassica napus L.).
International journal of molecular sciences.
2020 Feb; 21(4):. doi:
10.3390/ijms21041345. [PMID: 32079260] - Qian Yu, Ping Zhang, Yuhan He, Zhifeng Xu, Xiulong He, Yuan Hu, Hongjun Zhang, Lin He. Dissipation Dynamics and Residue of Four Herbicides in Paddy Fields Using HPLC-MS/MS and GC-MS.
International journal of environmental research and public health.
2019 01; 16(2):. doi:
10.3390/ijerph16020236. [PMID: 30650669] - Lanlan Sun, Hongle Xu, Hongdan Hao, Shiheng An, Chuantao Lu, Renhai Wu, Wangcang Su. Effects of bensulfuron-methyl residue on photosynthesis and chlorophyll fluorescence in leaves of cucumber seedlings.
PloS one.
2019; 14(4):e0215486. doi:
10.1371/journal.pone.0215486. [PMID: 31013318] - Dhirendra Fartyal, Aakrati Agarwal, Donald James, Bhabesh Borphukan, Babu Ram, Vijay Sheri, Pawan K Agrawal, V Mohan Murali Achary, M K Reddy. Developing dual herbicide tolerant transgenic rice plants for sustainable weed management.
Scientific reports.
2018 08; 8(1):11598. doi:
10.1038/s41598-018-29554-9. [PMID: 30072810] - Yali Zheng, Lili Gu, Junli Shi, Mengxiao Zhang, Guanghui Kong, Zhijun Li, Yi Han, Jian Peng. [Determination of sulfonylurea herbicide residues in tobacco leaves by molecularly imprinted-solid phase extraction-high performance liquid chromatography].
Se pu = Chinese journal of chromatography.
2018 Jul; 36(7):659-664. doi:
10.3724/sp.j.1123.2018.01010. [PMID: 30136538] - Rafael M Pedroso, Kassim Al-Khatib, Bradley D Hanson, Albert J Fischer. A high-throughput, modified ALS activity assay for Cyperus difformis and Schoenoplectus mucronatus seedlings.
Pesticide biochemistry and physiology.
2017 Jan; 135(?):78-81. doi:
10.1016/j.pestbp.2016.06.001. [PMID: 28043335] - Songhong Wei, Pingsheng Li, Mingshan Ji, Qin Dong, Haining Wang. Target-site resistance to bensulfuron-methyl in Sagittaria trifolia L. populations.
Pesticide biochemistry and physiology.
2015 Oct; 124(?):81-5. doi:
10.1016/j.pestbp.2015.05.001. [PMID: 26453234] - Jian Zhou, Zegang Wang, Zhiwei Huang, Chao Lu, Zhuo Han, Jianfeng Zhang, Huimin Jiang, Cailin Ge, Juncheng Yang. Expression of sulfur uptake assimilation-related genes in response to cadmium, bensulfuron-methyl and their co-contamination in rice roots.
Journal of environmental sciences (China).
2014 Mar; 26(3):650-61. doi:
10.1016/s1001-0742(13)60446-5. [PMID: 25079279] - Yu-Ting Lee, Chang-Jun Cui, Eve W L Chow, Nason Pue, Thierry Lonhienne, Jian-Guo Wang, James A Fraser, Luke W Guddat. Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase.
Journal of medicinal chemistry.
2013 Jan; 56(1):210-9. doi:
10.1021/jm301501k. [PMID: 23237384] - Lihua Yang, Daoxin Gong, Jing Tang, Junkai Luo, Chunxia Ding. [Simultaneous determination of bensulfuron-methyl and mefenacet residues in paddy field using high performance liquid chromatography].
Se pu = Chinese journal of chromatography.
2012 Jan; 30(1):71-5. doi:
10.3724/sp.j.1123.2011.09021. [PMID: 22667095] - Hagai Yasuor, Wei Zou, Vladimir V Tolstikov, Ronald S Tjeerdema, Albert J Fischer. Differential oxidative metabolism and 5-ketoclomazone accumulation are involved in Echinochloa phyllopogon resistance to clomazone.
Plant physiology.
2010 May; 153(1):319-26. doi:
10.1104/pp.110.153296. [PMID: 20207709] - Aldo Merotto, Marie Jasieniuk, Maria D Osuna, Francesco Vidotto, Aldo Ferrero, Albert J Fischer. Cross-resistance to herbicides of five ALS-inhibiting groups and sequencing of the ALS gene in Cyperus difformis L.
Journal of agricultural and food chemistry.
2009 Feb; 57(4):1389-98. doi:
10.1021/jf802758c. [PMID: 19191488] - Wei Zhang, Jin-Jun Wang. [Effects of solution pH and simulated acid rain on the behavior of two sulfonylurea herbicides in soil].
Ying yong sheng tai xue bao = The journal of applied ecology.
2007 Mar; 18(3):613-9. doi:
. [PMID: 17552202] - Youbin Si, Jing Zhou, Huaiman Chen, Dongmei Zhou, Yongde Yue. Effects of humic substances on photodegradation of bensulfuron-methyl on dry soil surfaces.
Chemosphere.
2004 Sep; 56(10):967-72. doi:
10.1016/j.chemosphere.2004.04.059. [PMID: 15268963] - You-Bin Si, Yong-De Yue, Huai-Man Chen, Dong-Mei Zhou. Photodegradation of bensulfuron-methyl on soil surface.
Pest management science.
2004 Mar; 60(3):286-90. doi:
10.1002/ps.803. [PMID: 15025240] - Youbin Si, Jing Zhou, Huaiman Chen, Dongmei Zhou. Photostabilization of the herbicide bensulfuron-methyl by using organoclays.
Chemosphere.
2004 Feb; 54(7):943-50. doi:
10.1016/j.chemosphere.2003.09.033. [PMID: 14637352] - J P Ruiz-Santaella, Y Bakkaliu, M D Osuna, R de Prado. Evaluation of resistance in Cyperus difformis populations to ALS inhibiting herbicides.
Communications in agricultural and applied biological sciences.
2004; 69(3):91-6. doi:
. [PMID: 15759399] - Yong In Kuk, Ha Il Jung, Oh Do Kwon, Do Jin Lee, Nilda R Burgos, Ja Ock Guh. Sulfonylurea herbicide-resistant Monochoria vaginalis in Korean rice culture.
Pest management science.
2003 Sep; 59(9):949-61. doi:
10.1002/ps.722. [PMID: 12974347] - Jae Koo Lee, Ki Chang Ahn, Oee Sook Park, Yong Kwan Ko, Dae-Whang Kim. Development of an immunoassay for the residues of the herbicide bensulfuron-methyl.
Journal of agricultural and food chemistry.
2002 Mar; 50(7):1791-803. doi:
10.1021/jf011150b. [PMID: 11902914] - G Wang, J Yuan, K Matsumoto, Z Hu. Homogeneous time-resolved fluoroimmunoassay of bensulfuron-methyl by using terbium fluorescence energy transfer.
Talanta.
2001 Dec; 55(6):1119-25. doi:
10.1016/s0039-9140(01)00526-4. [PMID: 18968465] - J Yuan, G Wang, K Majima, K Matsumoto. Synthesis of a terbium fluorescent chelate and its application to time-resolved fluoroimmunoassay.
Analytical chemistry.
2001 Apr; 73(8):1869-76. doi:
10.1021/ac0013305. [PMID: 11338604] - M S Yun, I S Shim, K Usui. Involvement of cytochrome P-450 enzyme activity in the selectivity and safening action of pyrazosulfuron-ethyl.
Pest management science.
2001 Mar; 57(3):283-8. doi:
10.1002/ps.298. [PMID: 11455659] - S A Mabury, J S Cox, D G Crosby. Environmental fate of rice pesticides in California.
Reviews of environmental contamination and toxicology.
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