(+)-Fargesin (BioDeep_00001877047)

   


代谢物信息卡片


(+)-Fargesin

化学式: C21H22O6 (370.1416)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=C(C=C(C=C1)C2C3COC(C3CO2)C4=CC5=C(C=C4)OCO5)OC
InChI: InChI=1S/C21H22O6/c1-22-16-5-3-12(7-18(16)23-2)20-14-9-25-21(15(14)10-24-20)13-4-6-17-19(8-13)27-11-26-17/h3-8,14-15,20-21H,9-11H2,1-2H3

描述信息

同义名列表

1 个代谢物同义名

(+)-Fargesin



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

18 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AIMP2, CDK1, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP3A4, PIK3C3, PTGS2
Peripheral membrane protein 3 CYP2B6, GORASP1, PTGS2
Endoplasmic reticulum membrane 11 CDK1, CYP1A2, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP3A4, PTGS2, UGT1A10, UGT1A3
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 4 AIMP2, CDK1, JUND, PPARA
autophagosome 1 PIK3C3
cytosol 4 AIMP2, CDK1, PIK3C3, SLC2A4
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
trans-Golgi network 1 SLC2A4
centrosome 1 CDK1
nucleoplasm 3 CDK1, JUND, PPARA
RNA polymerase II transcription regulator complex 1 JUND
Cell membrane 2 SLC2A4, TNF
Cytoplasmic side 1 GORASP1
Multi-pass membrane protein 1 SLC2A4
Golgi apparatus membrane 1 GORASP1
cell surface 1 TNF
glutamatergic synapse 1 PIK3C3
Golgi apparatus 1 GORASP1
Golgi membrane 2 GORASP1, INS
neuronal cell body 1 TNF
sarcolemma 1 SLC2A4
Cytoplasm, cytosol 1 AIMP2
Presynapse 1 SLC2A4
endosome 1 PIK3C3
plasma membrane 5 CYP2C19, CYP2C8, CYP2C9, SLC2A4, TNF
Membrane 8 AIMP2, CDK1, CYP2D6, CYP3A4, PIK3C3, SLC2A4, UGT1A10, UGT1A3
caveola 1 PTGS2
extracellular exosome 2 CDK1, SLC2A4
endoplasmic reticulum 4 CYP2D6, PTGS2, UGT1A10, UGT1A3
extracellular space 3 IL4, INS, TNF
perinuclear region of cytoplasm 1 SLC2A4
mitochondrion 2 CDK1, CYP2D6
protein-containing complex 1 PTGS2
intracellular membrane-bounded organelle 7 CYP1A2, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP3A4
Microsome membrane 6 CYP1A2, CYP2B6, CYP2C9, CYP2D6, CYP3A4, PTGS2
Secreted 2 IL4, INS
extracellular region 3 IL4, INS, TNF
Single-pass membrane protein 3 CYP2D6, UGT1A10, UGT1A3
mitochondrial matrix 1 CDK1
transcription regulator complex 1 JUND
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 CDK1
external side of plasma membrane 2 SLC2A4, TNF
multivesicular body 1 SLC2A4
T-tubule 1 SLC2A4
midbody 2 CDK1, PIK3C3
clathrin-coated pit 1 SLC2A4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cytoplasm, perinuclear region 1 SLC2A4
Membrane raft 2 SLC2A4, TNF
GABA-ergic synapse 1 PIK3C3
cis-Golgi network 1 GORASP1
Peroxisome 1 PIK3C3
sarcoplasmic reticulum 1 SLC2A4
axoneme 1 PIK3C3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 PIK3C3
neuron projection 1 PTGS2
chromatin 2 JUND, PPARA
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 PIK3C3
mitotic spindle 1 CDK1
chromosome, telomeric region 1 CDK1
Endomembrane system 1 SLC2A4
endosome lumen 1 INS
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
Cytoplasmic vesicle membrane 1 SLC2A4
clathrin-coated vesicle 1 SLC2A4
trans-Golgi network transport vesicle 1 SLC2A4
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, PTGS2
transcription repressor complex 1 JUND
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GORASP1, INS
presynaptic endosome 1 PIK3C3
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
vesicle membrane 1 SLC2A4
spindle microtubule 1 CDK1
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
cyclin-dependent protein kinase holoenzyme complex 1 CDK1
postsynaptic endosome 1 PIK3C3
transcription factor AP-1 complex 1 JUND
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
Autolysosome 1 PIK3C3
cyclin A1-CDK1 complex 1 CDK1
cyclin A2-CDK1 complex 1 CDK1
cyclin B1-CDK1 complex 1 CDK1
insulin-responsive compartment 1 SLC2A4
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Yuting Zhang, Rui Ma, Juan Wang. Protective effects of fargesin on cadmium-induced lung injury through regulating aryl hydrocarbon receptor. Journal of biochemical and molecular toxicology. 2022 Nov; 36(11):e23197. doi: 10.1002/jbt.23197. [PMID: 35983679]
  • Gang Wang, Jia-Hui Gao, Lin-Hao He, Xiao-Hua Yu, Zhen-Wang Zhao, Jin Zou, Feng-Jiao Wen, Li Zhou, Xiang-Jun Wan, Chao-Ke Tang. Fargesin alleviates atherosclerosis by promoting reverse cholesterol transport and reducing inflammatory response. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2020 05; 1865(5):158633. doi: 10.1016/j.bbalip.2020.158633. [PMID: 31988050]
  • Bei Yue, Yi-Jing Ren, Jing-Jing Zhang, Xiao-Ping Luo, Zhi-Lun Yu, Gai-Yan Ren, A-Ning Sun, Chao Deng, Zheng-Tao Wang, Wei Dou. Anti-Inflammatory Effects of Fargesin on Chemically Induced Inflammatory Bowel Disease in Mice. Molecules (Basel, Switzerland). 2018 Jun; 23(6):. doi: 10.3390/molecules23061380. [PMID: 29880739]
  • Vinod Bhatt, Sushila Sharma, Neeraj Kumar, Upendra Sharma, Bikram Singh. Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF-MS/MS. Journal of pharmaceutical and biomedical analysis. 2017 Jan; 132(?):46-55. doi: 10.1016/j.jpba.2016.09.035. [PMID: 27693952]
  • Sha Sha, Dandan Xu, Yanwei Wang, Weifang Zhao, Xiaoni Li. Antihypertensive effects of fargesin in vitro and in vivo via attenuating oxidative stress and promoting nitric oxide release. Canadian journal of physiology and pharmacology. 2016 Aug; 94(8):900-6. doi: 10.1139/cjpp-2015-0615. [PMID: 27409158]
  • Yan-qun Liu, Sheng-hui Yang, Qiang Liu, Gang Pei, Wei-wei Pan, Min Liu, Cai-yun Peng. [Study on chemical constituents of Zanthoxyli cortex's ethyl acetate extract]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2013 Nov; 36(11):1792-5. doi: . [PMID: 24956821]
  • Young-Sil Lee, Byung-Yoon Cha, Sun-Sil Choi, Yumiko Harada, Bong-Keun Choi, Takayuki Yonezawa, Toshiaki Teruya, Kazuo Nagai, Je-Tae Woo. Fargesin improves lipid and glucose metabolism in 3T3-L1 adipocytes and high-fat diet-induced obese mice. BioFactors (Oxford, England). 2012 Jul; 38(4):300-8. doi: 10.1002/biof.1022. [PMID: 22674784]
  • Ji Hyun Jeong, Dong Kyun Kim, Hye Young Ji, Sei Ryang Oh, Hyung-Kyu Lee, Hye Suk Lee. Liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry for the simultaneous determination of dimethoxyaschantin, dimethylliroresinol, dimethylpinoresinol, epimagnolin A, fargesin and magnolin in rat plasma. Biomedical chromatography : BMC. 2011 Aug; 25(8):879-89. doi: 10.1002/bmc.1538. [PMID: 21058411]
  • Jin Ah Baek, Yang Deok Lee, Chan Bog Lee, Hyeon Kyu Go, Jin Pyo Kim, Jeong Ju Seo, Yang Keun Rhee, A Mi Kim, Dong Jib Na. Extracts of Magnoliae flos inhibit inducible nitric oxide synthase via ERK in human respiratory epithelial cells. Nitric oxide : biology and chemistry. 2009 Mar; 20(2):122-8. doi: 10.1016/j.niox.2008.10.003. [PMID: 18976718]