(4Z,7R,8E,10Z,12E,14E,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid (BioDeep_00001876453)

   


代谢物信息卡片


(4Z,7R,8E,10Z,12E,14E,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid

化学式: C22H32O5 (376.225)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC=CCC(C(C=CC=CC=CC=CC(CC=CCCC(=O)O)O)O)O
InChI: InChI=1S/C22H32O5/c1-2-3-9-16-20(24)21(25)17-12-7-5-4-6-10-14-19(23)15-11-8-13-18-22(26)27/h3-12,14,17,19-21,23-25H,2,13,15-16,18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,11-8-,14-10+,17-12+/t19-,20-,21?/m0/s1



数据库引用编号

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分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ALOX5, BDNF, ELANE, FPR2, MTOR, POMC, VEGFA
Peripheral membrane protein 2 ALOX5, MTOR
Endosome membrane 1 FFAR4
Endoplasmic reticulum membrane 1 MTOR
Nucleus 3 MTOR, PLCZ1, VEGFA
cytosol 4 ALOX5, ELANE, MTOR, PLCZ1
dendrite 2 BDNF, MTOR
phagocytic vesicle 2 ELANE, MTOR
nucleoplasm 3 ALOX5, MTOR, PLCZ1
Cell membrane 7 FFAR4, FPR2, GPR18, SLC38A1, SLC6A19, TNF, TRPV1
Cytoplasmic side 1 MTOR
Multi-pass membrane protein 7 FFAR4, FPR2, GPR18, SLC38A1, SLC5A1, SLC6A19, TRPV1
Golgi apparatus membrane 1 MTOR
cell surface 3 ELANE, TNF, VEGFA
Golgi apparatus 2 NPY, VEGFA
Golgi membrane 1 MTOR
lysosomal membrane 2 FFAR4, MTOR
neuronal cell body 3 SLC38A1, TNF, TRPV1
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 1 ALOX5
Lysosome 1 MTOR
plasma membrane 8 FFAR4, FPR2, GPR18, SLC38A1, SLC5A1, SLC6A19, TNF, TRPV1
Membrane 8 BDNF, FPR2, GPR18, MTOR, SLC38A1, SLC6A19, TRPV1, VEGFA
apical plasma membrane 2 SLC5A1, SLC6A19
axon 2 BDNF, SLC38A1
basolateral plasma membrane 1 SLC38A1
extracellular exosome 4 ELANE, SLC38A1, SLC5A1, SLC6A19
Lysosome membrane 2 FFAR4, MTOR
endoplasmic reticulum 1 VEGFA
extracellular space 11 ALOX5, BDNF, CCL2, CXCL8, ELANE, IL10, IL6, NPY, POMC, TNF, VEGFA
perinuclear region of cytoplasm 4 ALOX5, BDNF, PLCZ1, SLC5A1
adherens junction 1 VEGFA
Microsome membrane 1 MTOR
pronucleus 1 PLCZ1
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Secreted 8 BDNF, CCL2, CXCL8, IL10, IL6, NPY, POMC, VEGFA
extracellular region 11 ALOX5, BDNF, CCL2, CXCL8, ELANE, IL10, IL6, NPY, POMC, TNF, VEGFA
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 1 MTOR
ciliary membrane 1 FFAR4
Nucleus membrane 1 ALOX5
nuclear membrane 1 ALOX5
external side of plasma membrane 2 TNF, TRPV1
Secreted, extracellular space, extracellular matrix 1 VEGFA
nucleolus 1 PLCZ1
Early endosome 1 SLC5A1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 1 TRPV1
Apical cell membrane 2 SLC5A1, SLC6A19
Cytoplasm, perinuclear region 2 ALOX5, PLCZ1
Membrane raft 1 TNF
GABA-ergic synapse 2 NPY, TRPV1
extracellular matrix 1 VEGFA
intracellular vesicle 1 SLC5A1
Nucleus, PML body 1 MTOR
PML body 1 MTOR
collagen-containing extracellular matrix 1 ELANE
secretory granule 3 ELANE, POMC, VEGFA
Postsynaptic cell membrane 1 TRPV1
Cell projection, neuron projection 1 TRPV1
cilium 1 FFAR4
phagocytic cup 1 TNF
brush border membrane 2 SLC5A1, SLC6A19
[Isoform 2]: Cell membrane 1 FFAR4
nuclear envelope 2 ALOX5, MTOR
Nucleus envelope 1 ALOX5
Endomembrane system 1 MTOR
Cytoplasmic vesicle membrane 1 GPR18
specific granule membrane 1 FPR2
tertiary granule membrane 1 FPR2
ficolin-1-rich granule lumen 1 ALOX5
secretory granule lumen 2 ALOX5, POMC
endoplasmic reticulum lumen 2 BDNF, IL6
nuclear matrix 1 ALOX5
transcription repressor complex 1 ELANE
platelet alpha granule lumen 1 VEGFA
specific granule lumen 1 ELANE
endocytic vesicle 1 FFAR4
azurophil granule lumen 1 ELANE
neuronal dense core vesicle 1 NPY
Nucleus matrix 1 ALOX5
nuclear envelope lumen 1 ALOX5
ficolin-1-rich granule membrane 1 FPR2
external side of apical plasma membrane 1 SLC38A1
[Isoform 1]: Cell membrane 1 FFAR4
Cytoplasmic vesicle, phagosome 2 ELANE, MTOR
Cell projection, cilium membrane 1 FFAR4
Cell projection, dendritic spine membrane 1 TRPV1
dendritic spine membrane 1 TRPV1
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle 1 NPY
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
sperm head 1 PLCZ1
interleukin-6 receptor complex 1 IL6
Nucleus intermembrane space 1 ALOX5
intracellular organelle 1 SLC5A1
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Michael J Zhang, Brian E Sansbury, Jason Hellmann, James F Baker, Luping Guo, Caitlin M Parmer, Joshua C Prenner, Daniel J Conklin, Aruni Bhatnagar, Mark A Creager, Matthew Spite. Resolvin D2 Enhances Postischemic Revascularization While Resolving Inflammation. Circulation. 2016 Aug; 134(9):666-680. doi: 10.1161/circulationaha.116.021894. [PMID: 27507404]
  • Chul-Kyu Park, Zhen-Zhong Xu, Tong Liu, Ning Lü, Charles N Serhan, Ru-Rong Ji. Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 Dec; 31(50):18433-8. doi: 10.1523/jneurosci.4192-11.2011. [PMID: 22171045]