AI3-23606 (BioDeep_00001875812)

Main id: BioDeep_00000009891

 


代谢物信息卡片


2-NITROFURAN

化学式: C4H3NO3 (113.0113)
中文名称: 2-硝呋喃, 2-硝基呋喃
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=COC(=C1)[N+](=O)[O-]
InChI: InChI=1S/C4H3NO3/c6-5(7)4-2-1-3-8-4/h1-3H

描述信息

同义名列表

4 个代谢物同义名

2-NITROFURAN; AI3-23606; 2-Nitrofuran; 2-Nitrofuran



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ABCB1, BCL2, CAT, CTNNB1, FZD2, GEMIN4, HPGDS, NQO1, STAT3, XDH
Peripheral membrane protein 1 HSD17B6
Endoplasmic reticulum membrane 1 BCL2
Nucleus 5 BCL2, CTNNB1, GABPA, NQO1, STAT3
cytosol 10 BCL2, CAT, CTNNB1, GEMIN4, GPT, GSR, HPGDS, NQO1, STAT3, XDH
dendrite 1 NQO1
nuclear body 1 GEMIN4
centrosome 1 CTNNB1
nucleoplasm 6 CD2, CTNNB1, GABPA, GEMIN4, HPGDS, STAT3
RNA polymerase II transcription regulator complex 1 STAT3
Cell membrane 6 ABCB1, CD2, CTNNB1, FZD2, JAG1, TNF
lamellipodium 1 CTNNB1
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 3 ABCB1, ATP4A, FZD2
Synapse 2 CTNNB1, NQO1
cell cortex 1 CTNNB1
cell junction 1 CTNNB1
cell surface 3 ABCB1, CD2, TNF
glutamatergic synapse 1 CTNNB1
Golgi apparatus 1 CD2
neuronal cell body 2 NQO1, TNF
presynaptic membrane 1 CTNNB1
Cytoplasm, cytosol 1 NQO1
Lysosome 1 CTSV
plasma membrane 8 ABCB1, ATP4A, CD2, CTNNB1, FZD2, JAG1, STAT3, TNF
Membrane 8 ABCB1, ATP4A, BCL2, CAT, CTNNB1, GEMIN4, JAG1, NQO1
apical plasma membrane 3 ABCB1, ATP4A, JAG1
basolateral plasma membrane 1 CTNNB1
extracellular exosome 7 ABCB1, ALDH2, CAT, CTNNB1, GEMIN4, GPT, GSR
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 BCL2, HSD17B6
extracellular space 4 ATP4A, CTSV, TNF, XDH
lysosomal lumen 1 CTSV
perinuclear region of cytoplasm 1 CTNNB1
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 2 CTNNB1, JAG1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
mitochondrion 4 ALDH2, BCL2, CAT, GSR
protein-containing complex 4 BCL2, CAT, CD2, CTNNB1
intracellular membrane-bounded organelle 3 CAT, HPGDS, HSD17B6
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 2 CD2, JAG1
extracellular region 5 CAT, CD2, CTSV, JAG1, TNF
cytoplasmic side of plasma membrane 1 CD2
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
Mitochondrion matrix 1 ALDH2
mitochondrial matrix 3 ALDH2, CAT, GSR
transcription regulator complex 2 CTNNB1, STAT3
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 3 CD2, GSR, TNF
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
nucleolus 1 GEMIN4
Wnt signalosome 1 CTNNB1
apical part of cell 1 CTNNB1
cell-cell junction 2 CD2, CTNNB1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 1 CTNNB1
Apical cell membrane 2 ABCB1, ATP4A
Membrane raft 1 TNF
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 CTNNB1
focal adhesion 3 CAT, CTNNB1, FZD2
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
Peroxisome 2 CAT, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
fascia adherens 1 CTNNB1
lateral plasma membrane 1 CTNNB1
chromatin 2 GABPA, STAT3
phagocytic cup 1 TNF
cell periphery 1 CTNNB1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
spindle pole 1 CTNNB1
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
Endomembrane system 1 CTNNB1
euchromatin 1 CTNNB1
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
beta-catenin-TCF complex 1 CTNNB1
presynaptic active zone cytoplasmic component 1 CTNNB1
Gemini of coiled bodies 1 GEMIN4
SMN complex 1 GEMIN4
SMN-Sm protein complex 1 GEMIN4
clathrin-coated endocytic vesicle membrane 1 FZD2
Cajal body 1 GEMIN4
protein-DNA complex 1 CTNNB1
external side of apical plasma membrane 1 ABCB1
catenin complex 1 CTNNB1
small nuclear ribonucleoprotein complex 1 GEMIN4
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
BAD-BCL-2 complex 1 BCL2
beta-catenin-TCF7L2 complex 1 CTNNB1
potassium:proton exchanging ATPase complex 1 ATP4A
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Mina-Olga Aletrari, Craig McKibbin, Helen Williams, Vidya Pawar, Paola Pietroni, J Michael Lord, Sabine L Flitsch, Roger Whitehead, Eileithyia Swanton, Stephen High, Robert A Spooner. Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways. PloS one. 2011; 6(7):e22713. doi: 10.1371/journal.pone.0022713. [PMID: 21799938]
  • Annamaria Buschini, Lisa Ferrarini, Susanna Franzoni, Serena Galati, Mirca Lazzaretti, Francesca Mussi, Cristina Northfleet de Albuquerque, Tânia Maria Araújo Domingues Zucchi, Paola Poli. Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole. Journal of parasitology research. 2009; 2009(?):463575. doi: 10.1155/2009/463575. [PMID: 20981287]
  • María I Amaro, Melina Monasterios, Milagros Avendaño, Jaime Charris. Preliminary evaluation of the toxicity of some synthetic furan derivatives in two cell lines and Artemia salina. Journal of applied toxicology : JAT. 2009 Jan; 29(1):36-41. doi: 10.1002/jat.1379. [PMID: 18720481]
  • M J Iatropoulos, C X Wang, E von Keutz, G M Williams. Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of Nifurtimox, an antitrypanosomiasis drug. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 2006 Jul; 57(5-6):397-404. doi: 10.1016/j.etp.2006.01.005. [PMID: 16616835]
  • O O Novikov, I P Pavlik, L S Novikova, A B Konovalenko. Analysis of 5-nitrofuran derivatives in biological objects. Bulletin of experimental biology and medicine. 2003 Jan; 135(1):101-2. doi: 10.1023/a:1023422702204. [PMID: 12717526]