L-Threonine phosphate (BioDeep_00001871992)

Main id: BioDeep_00000003159

 


代谢物信息卡片


threoninium dihydrogen phosphate

化学式: C4H10NO6P (199.024573)
中文名称: L-2-氨基-3-羟基丁酸-3-磷酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.34%

分子结构信息

SMILES: CC(C(C(=O)O)N)OP(=O)(O)O
InChI: InChI=1S/C4H10NO6P/c1-2(3(5)4(6)7)11-12(8,9)10/h2-3H,5H2,1H3,(H,6,7)(H2,8,9,10)/t2-,3+/m1/s1

描述信息

A L-threonine derivative phosphorylated at the side-chain hydroxy function.
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents

同义名列表

4 个代谢物同义名

threoninium dihydrogen phosphate; L-Threonine O-3-phosphate; L-Threonine phosphate; O-Phospho-L-threonine



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Min Chen, Lan Ni, Jing Chen, Manman Sun, Caihua Qin, Gang Zhang, Aying Zhang, Mingyi Jiang. Rice calcium/calmodulin-dependent protein kinase directly phosphorylates a mitogen-activated protein kinase kinase to regulate abscisic acid responses. The Plant cell. 2021 07; 33(5):1790-1812. doi: 10.1093/plcell/koab071. [PMID: 33630095]
  • Jie Yang, Hang He, Yuming He, Qiaozhen Zheng, Qingzhong Li, Xin Feng, Pengcheng Wang, Guocheng Qin, Yangtao Gu, Ping Wu, Chao Peng, Shilei Sun, Yi Zhang, Mingzhang Wen, Rong Chen, Yang Zhao, Tongda Xu. TMK1-based auxin signaling regulates abscisic acid responses via phosphorylating ABI1/2 in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America. 2021 06; 118(24):. doi: 10.1073/pnas.2102544118. [PMID: 34099554]
  • Jianfang Li, Huapeng Zhou, Yan Zhang, Zhen Li, Yongqing Yang, Yan Guo. The GSK3-like Kinase BIN2 Is a Molecular Switch between the Salt Stress Response and Growth Recovery in Arabidopsis thaliana. Developmental cell. 2020 11; 55(3):367-380.e6. doi: 10.1016/j.devcel.2020.08.005. [PMID: 32891194]
  • Xiaoli Zhang, Luis R Flores, Michael C Keeling, Kristina Sliogeryte, Núria Gavara. Ezrin Phosphorylation at T567 Modulates Cell Migration, Mechanical Properties, and Cytoskeletal Organization. International journal of molecular sciences. 2020 Jan; 21(2):. doi: 10.3390/ijms21020435. [PMID: 31936668]
  • Andrea Trotta, Azfar Ali Bajwa, Ilaria Mancini, Virpi Paakkarinen, Mathias Pribil, Eva-Mari Aro. The Role of Phosphorylation Dynamics of CURVATURE THYLAKOID 1B in Plant Thylakoid Membranes. Plant physiology. 2019 12; 181(4):1615-1631. doi: 10.1104/pp.19.00942. [PMID: 31615849]
  • Xin Zhou, Lan Ni, Yaqin Liu, Mingyi Jiang. Phosphorylation of bip130 by OsMPK1 regulates abscisic acid-induced antioxidant defense in rice. Biochemical and biophysical research communications. 2019 06; 514(3):750-755. doi: 10.1016/j.bbrc.2019.04.183. [PMID: 31078272]
  • Geneviève Hamel-Côté, Fanny Lapointe, Daniel Gendron, Marek Rola-Pleszczynski, Jana Stankova. Regulation of platelet-activating factor-induced interleukin-8 expression by protein tyrosine phosphatase 1B. Cell communication and signaling : CCS. 2019 03; 17(1):21. doi: 10.1186/s12964-019-0334-6. [PMID: 30832675]
  • Lidiya P Dubytska, Ronald L Thune. Edwardsiella ictaluri type III secretion system (T3SS) effector EseN is a phosphothreonine lyase that inactivates ERK1/2. Diseases of aquatic organisms. 2018 Sep; 130(2):117-129. doi: 10.3354/dao03255. [PMID: 30198487]
  • Mohammad A Dallak. Acylated ghrelin induces but deacylated ghrelin prevents hepatic steatosis and insulin resistance in lean rats: Effects on DAG/ PKC/JNK pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2018 Sep; 105(?):299-311. doi: 10.1016/j.biopha.2018.05.098. [PMID: 29860222]
  • Franck Anicet Ditengou, Dulceneia Gomes, Hugues Nziengui, Philip Kochersperger, Hanna Lasok, Violante Medeiros, Ivan A Paponov, Szilvia Krisztina Nagy, Tímea Virág Nádai, Tamás Mészáros, Beáta Barnabás, Beata Izabela Ditengou, Katja Rapp, Linlin Qi, Xugang Li, Claude Becker, Chuanyou Li, Róbert Dóczi, Klaus Palme. Characterization of auxin transporter PIN6 plasma membrane targeting reveals a function for PIN6 in plant bolting. The New phytologist. 2018 03; 217(4):1610-1624. doi: 10.1111/nph.14923. [PMID: 29218850]
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  • Marta Cifuentes, Sylvie Jolivet, Laurence Cromer, Hirofumi Harashima, Petra Bulankova, Charlotte Renne, Wayne Crismani, Yuko Nomura, Hirofumi Nakagami, Keiko Sugimoto, Arp Schnittger, Karel Riha, Raphael Mercier. TDM1 Regulation Determines the Number of Meiotic Divisions. PLoS genetics. 2016 Feb; 12(2):e1005856. doi: 10.1371/journal.pgen.1005856. [PMID: 26871453]
  • DongHyuk Lee, Gildas Bourdais, Gang Yu, Silke Robatzek, Gitta Coaker. Phosphorylation of the Plant Immune Regulator RPM1-INTERACTING PROTEIN4 Enhances Plant Plasma Membrane H⁺-ATPase Activity and Inhibits Flagellin-Triggered Immune Responses in Arabidopsis. The Plant cell. 2015 Jul; 27(7):2042-56. doi: 10.1105/tpc.114.132308. [PMID: 26198070]
  • Euan Parnell, Andreas Koschinski, Manuela Zaccolo, Ryan T Cameron, George S Baillie, Gemma L Baillie, Alison Porter, Stuart P McElroy, Stephen J Yarwood. Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells. Biochimica et biophysica acta. 2015 Jul; 1853(7):1749-58. doi: 10.1016/j.bbamcr.2015.04.009. [PMID: 25913012]
  • Bo Li, Shan Jiang, Xiao Yu, Cheng Cheng, Sixue Chen, Yanbing Cheng, Joshua S Yuan, Daohong Jiang, Ping He, Libo Shan. Phosphorylation of trihelix transcriptional repressor ASR3 by MAP KINASE4 negatively regulates Arabidopsis immunity. The Plant cell. 2015 Mar; 27(3):839-56. doi: 10.1105/tpc.114.134809. [PMID: 25770109]
  • Victor Babich, Francesca Di Sole. The Na+/H+ Exchanger-3 (NHE3) Activity Requires Ezrin Binding to Phosphoinositide and Its Phosphorylation. PloS one. 2015; 10(6):e0129306. doi: 10.1371/journal.pone.0129306. [PMID: 26042733]
  • E Boex-Fontvieille, M Daventure, M Jossier, M Hodges, M Zivy, G Tcherkez. Phosphorylation pattern of Rubisco activase in Arabidopsis leaves. Plant biology (Stuttgart, Germany). 2014 May; 16(3):550-7. doi: 10.1111/plb.12100. [PMID: 24119201]
  • Joanne L Parker, Simon Newstead. Molecular basis of nitrate uptake by the plant nitrate transporter NRT1.1. Nature. 2014 Mar; 507(7490):68-72. doi: 10.1038/nature13116. [PMID: 24572366]
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  • Jer-Sheng Lin, Hsin-Hui Wu, Pang-Hung Hsu, Lay-Sun Ma, Yin-Yuin Pang, Ming-Daw Tsai, Erh-Min Lai. Fha interaction with phosphothreonine of TssL activates type VI secretion in Agrobacterium tumefaciens. PLoS pathogens. 2014 Mar; 10(3):e1003991. doi: 10.1371/journal.ppat.1003991. [PMID: 24626341]
  • Xiao-Ning Zhang, Cecilia Mo, Wesley M Garrett, Bret Cooper. Phosphothreonine 218 is required for the function of SR45.1 in regulating flower petal development in Arabidopsis. Plant signaling & behavior. 2014; 9(7):e29134. doi: 10.4161/psb.29134. [PMID: 25763493]
  • Satoru Machida, Y Adam Yuan. Crystal structure of Arabidopsis thaliana Dawdle forkhead-associated domain reveals a conserved phospho-threonine recognition cleft for dicer-like 1 binding. Molecular plant. 2013 Jul; 6(4):1290-300. doi: 10.1093/mp/sst007. [PMID: 23313986]
  • Yoshinori Ban, Yuhko Kobayashi, Tomomi Hara, Takahiro Hamada, Takashi Hashimoto, Shin Takeda, Tsukaho Hattori. α-tubulin is rapidly phosphorylated in response to hyperosmotic stress in rice and Arabidopsis. Plant & cell physiology. 2013 Jun; 54(6):848-58. doi: 10.1093/pcp/pct065. [PMID: 23628996]
  • Supachai Topanurak, Joan D Ferraris, Jinxi Li, Yuichiro Izumi, Chester K Williams, Marjan Gucek, Guanghui Wang, Xiaoming Zhou, Maurice B Burg. High NaCl- and urea-induced posttranslational modifications that increase glycerophosphocholine by inhibiting GDPD5 phosphodiesterase. Proceedings of the National Academy of Sciences of the United States of America. 2013 Apr; 110(18):7482-7. doi: 10.1073/pnas.1305220110. [PMID: 23589856]
  • Małgorzata Janicka-Russak, Katarzyna Kabała. Abscisic acid and hydrogen peroxide induce modification of plasma membrane H(+)-ATPase from Cucumis sativus L. roots under heat shock. Journal of plant physiology. 2012 Nov; 169(16):1607-14. doi: 10.1016/j.jplph.2012.05.013. [PMID: 22749287]
  • Jürgen van Baal, John de Widt, Nullin Divecha, Wim J van Blitterswijk. Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor. The international journal of biochemistry & cell biology. 2012 Nov; 44(11):1791-9. doi: 10.1016/j.biocel.2012.06.021. [PMID: 22732145]
  • Rikard Fristedt, Wioleta Wasilewska, Elzbieta Romanowska, Alexander V Vener. Differential phosphorylation of thylakoid proteins in mesophyll and bundle sheath chloroplasts from maize plants grown under low or high light. Proteomics. 2012 Sep; 12(18):2852-61. doi: 10.1002/pmic.201200196. [PMID: 22833285]
  • Małgorzata Janicka-Russak, Katarzyna Kabała, Marek Burzynski. Different effect of cadmium and copper on H+-ATPase activity in plasma membrane vesicles from Cucumis sativus roots. Journal of experimental botany. 2012 Jun; 63(11):4133-42. doi: 10.1093/jxb/ers097. [PMID: 22451724]
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  • Man-Ho Oh, Hyoung Seok Kim, Xia Wu, Steven D Clouse, Raymond E Zielinski, Steven C Huber. Calcium/calmodulin inhibition of the Arabidopsis BRASSINOSTEROID-INSENSITIVE 1 receptor kinase provides a possible link between calcium and brassinosteroid signalling. The Biochemical journal. 2012 Apr; 443(2):515-23. doi: 10.1042/bj20111871. [PMID: 22309147]
  • Sébastien Pyr Dit Ruys, Xuemin Wang, Ewan M Smith, Gaëtan Herinckx, Nusrat Hussain, Mark H Rider, Didier Vertommen, Christopher G Proud. Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase. The Biochemical journal. 2012 Mar; 442(3):681-92. doi: 10.1042/bj20111530. [PMID: 22216903]
  • Neelja Singhal, Prashant Sharma, Manish Kumar, Beenu Joshi, Deepa Bisht. Analysis of intracellular expressed proteins of Mycobacterium tuberculosis clinical isolates. Proteome science. 2012 Mar; 10(1):14. doi: 10.1186/1477-5956-10-14. [PMID: 22375954]
  • Rachana Sainger, Juan B Grau, Paolo Poggio, Emanuela Branchetti, Joseph E Bavaria, Joseph H Gorman, Robert C Gorman, Giovanni Ferrari. Dephosphorylation of circulating human osteopontin correlates with severe valvular calcification in patients with calcific aortic valve disease. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2012 Mar; 17(2):111-8. doi: 10.3109/1354750x.2011.642407. [PMID: 22191734]
  • Małgorzata Janicka-Russak, Katarzyna Kabała, Anna Wdowikowska, Grażyna Kłobus. Response of plasma membrane H(+)-ATPase to low temperature in cucumber roots. Journal of plant research. 2012 03; 125(2):291-300. doi: 10.1007/s10265-011-0438-6. [PMID: 21638005]
  • Yafei Qi, Ute Armbruster, Christian Schmitz-Linneweber, Etienne Delannoy, Andeol Falcon de Longevialle, Thilo Rühle, Ian Small, Peter Jahns, Dario Leister. Arabidopsis CSP41 proteins form multimeric complexes that bind and stabilize distinct plastid transcripts. Journal of experimental botany. 2012 Feb; 63(3):1251-70. doi: 10.1093/jxb/err347. [PMID: 22090436]
  • Jessica Schmitz, Mark Aurel Schöttler, Stephan Krueger, Stefan Geimer, Anja Schneider, Tatjana Kleine, Dario Leister, Kirsten Bell, Ulf-Ingo Flügge, Rainer E Häusler. Defects in leaf carbohydrate metabolism compromise acclimation to high light and lead to a high chlorophyll fluorescence phenotype in Arabidopsis thaliana. BMC plant biology. 2012 Jan; 12(?):8. doi: 10.1186/1471-2229-12-8. [PMID: 22248311]
  • Mingjia Chen, Hongmei Zeng, Dewen Qiu, Lihua Guo, Xiufen Yang, Huaixing Shi, Tingting Zhou, Jing Zhao. Purification and characterization of a novel hypersensitive response-inducing elicitor from Magnaporthe oryzae that triggers defense response in rice. PloS one. 2012; 7(5):e37654. doi: 10.1371/journal.pone.0037654. [PMID: 22624059]
  • Anastasia Liapis, Fannie W Chen, Joanna P Davies, Rong Wang, Yiannis A Ioannou. MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding site. PloS one. 2012; 7(4):e34424. doi: 10.1371/journal.pone.0034424. [PMID: 22514632]
  • Yan Yang, Zhenyin Shi, Adili Reheman, Joseph W Jin, Conglei Li, Yiming Wang, Marc C Andrews, Pingguo Chen, Guangheng Zhu, Wenhua Ling, Heyu Ni. Plant food delphinidin-3-glucoside significantly inhibits platelet activation and thrombosis: novel protective roles against cardiovascular diseases. PloS one. 2012; 7(5):e37323. doi: 10.1371/journal.pone.0037323. [PMID: 22624015]
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  • Takeshi Terabayashi, Masaji Sakaguchi, Kaori Shinmyozu, Toshio Ohshima, Ai Johjima, Teru Ogura, Hiroaki Miki, Ryuichi Nishinakamura. Phosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney development. PloS one. 2012; 7(6):e39714. doi: 10.1371/journal.pone.0039714. [PMID: 22768111]
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