1-(sn-Glycero-3-phospho)-1D-myo-inositol (BioDeep_00001870376)
Main id: BioDeep_00000004622
代谢物信息卡片
1-(sn-Glycero-3-phospho)-1D-myo-inositol
化学式: C9H19O11P (334.0664954)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(COP(=O)(O)OC1C(C(C(C(C1O)O)O)O)O)O)O
InChI: InChI=1S/C9H19O11P/c10-1-3(11)2-19-21(17,18)20-9-7(15)5(13)4(12)6(14)8(9)16/h3-16H,1-2H2,(H,17,18)/t3-,4-,5-,6+,7-,8-,9-/m1/s1
描述信息
A myo-inositol monophosphate derivative that is 1D-myo-inositol substituted at position 1 by an sn-glycero-3-phospho group.
同义名列表
1 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:166490
- ChEBI: CHEBI:18321
- KEGG: C01225
- PubChem: 45480545
- CAS: 129830-95-1
- MetaboLights: MTBLC18321
- PubChem: 4447
- NIKKAJI: J1.337.792H
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Qi Zhang, Yan Li, Ping Sui, Xue-Heng Sun, Yufei Gao, Chun-Yan Wang. MALDI mass spectrometry imaging discloses the decline of sulfoglycosphingolipid and glycerophosphoinositol species in the brain regions related to cognition in a mouse model of Alzheimer's disease.
Talanta.
2023 Aug; 266(Pt 2):125022. doi:
10.1016/j.talanta.2023.125022. [PMID: 37619472] - Ignacio Piédrola, Sara Martínez, Ana Gradillas, Alma Villaseñor, Vanesa Alonso-Herranz, Isabel Sánchez-Vera, Esther Escudero, Isabel A Martín-Antoniano, Jose Felipe Varona, Andrés Ruiz, Jose María Castellano, Úrsula Muñoz, María C Sádaba. Deficiency in the production of antibodies to lipids correlates with increased lipid metabolism in severe COVID-19 patients.
Frontiers in immunology.
2023; 14(?):1188786. doi:
10.3389/fimmu.2023.1188786. [PMID: 37426663] - Benjamin P Robinson, Sarah Hawbaker, Annette Chiang, Eric M Jordahl, Sanket Anaokar, Alexiy Nikiforov, Ray W Bowman, Philip Ziegler, Ceara K McAtee, Jana Patton-Vogt, Allyson F O'Donnell. Alpha-arrestins Aly1/Art6 and Aly2/Art3 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis.
Biology of the cell.
2022 Jan; 114(1):3-31. doi:
10.1111/boc.202100007. [PMID: 34562280] - Ana Margarida Campos, Genoveffa Nuzzo, Alessia Varone, Paola Italiani, Diana Boraschi, Daniela Corda, Angelo Fontana. Direct LC-MS/MS Analysis of Extra- and Intracellular Glycerophosphoinositol in Model Cancer Cell Lines.
Frontiers in immunology.
2021; 12(?):646681. doi:
10.3389/fimmu.2021.646681. [PMID: 33737939] - Xinzhu Wang, Ruud Nijman, Stephane Camuzeaux, Caroline Sands, Heather Jackson, Myrsini Kaforou, Marieke Emonts, Jethro A Herberg, Ian Maconochie, Enitan D Carrol, Stephane C Paulus, Werner Zenz, Michiel Van der Flier, Ronald de Groot, Federico Martinon-Torres, Luregn J Schlapbach, Andrew J Pollard, Colin Fink, Taco T Kuijpers, Suzanne Anderson, Matthew R Lewis, Michael Levin, Myra McClure. Plasma lipid profiles discriminate bacterial from viral infection in febrile children.
Scientific reports.
2019 11; 9(1):17714. doi:
10.1038/s41598-019-53721-1. [PMID: 31776453] - Mariangela Vessichelli, Stefania Mariggiò, Alessia Varone, Pasquale Zizza, Angelomaria Di Santo, Concetta Amore, Giuseppe Dell'Elba, Adele Cutignano, Angelo Fontana, Carmela Cacciapuoti, Gaetano Di Costanzo, Mariastella Zannini, Tiziana de Cristofaro, Virgilio Evangelista, Daniela Corda. The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses.
The Journal of biological chemistry.
2017 08; 292(31):12828-12841. doi:
10.1074/jbc.m116.773861. [PMID: 28600357] - Carla D Jorge, Nuno Borges, Helena Santos. A novel pathway for the synthesis of inositol phospholipids uses cytidine diphosphate (CDP)-inositol as donor of the polar head group.
Environmental microbiology.
2015 Jul; 17(7):2492-504. doi:
10.1111/1462-2920.12734. [PMID: 25472423] - Laura Grauso, Stefania Mariggiò, Daniela Corda, Angelo Fontana, Adele Cutignano. An improved UPLC-MS/MS platform for quantitative analysis of glycerophosphoinositol in mammalian cells.
PloS one.
2015; 10(4):e0123198. doi:
10.1371/journal.pone.0123198. [PMID: 25860666] - Tanya C Burch, Giorgis Isaac, Christiana L Booher, Johng S Rhim, Paul Rainville, James Langridge, Andrew Baker, Julius O Nyalwidhe. Comparative Metabolomic and Lipidomic Analysis of Phenotype Stratified Prostate Cells.
PloS one.
2015; 10(8):e0134206. doi:
10.1371/journal.pone.0134206. [PMID: 26244785] - Graeme S V McDowell, Alexandre P Blanchard, Graeme P Taylor, Daniel Figeys, Stephen Fai, Steffany A L Bennett. Predicting glycerophosphoinositol identities in lipidomic datasets using VaLID (Visualization and Phospholipid Identification)--an online bioinformatic search engine.
BioMed research international.
2014; 2014(?):818670. doi:
10.1155/2014/818670. [PMID: 24701584] - Chin-Lu Tseng, Jiann-Wu Wei. Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells.
The Chinese journal of physiology.
2013 Apr; 56(2):90-100. doi:
10.4077/cjp.2013.bab094. [PMID: 23589925] - Teun Munnik. Analysis of D3-,4-,5-phosphorylated phosphoinositides using HPLC.
Methods in molecular biology (Clifton, N.J.).
2013; 1009(?):17-24. doi:
10.1007/978-1-62703-401-2_2. [PMID: 23681519] - Jana Patton-Vogt. Transport and metabolism of glycerophosphodiesters produced through phospholipid deacylation.
Biochimica et biophysica acta.
2007 Mar; 1771(3):337-42. doi:
10.1016/j.bbalip.2006.04.013. [PMID: 16781190] - Stefania Mariggiò, Cristiano Iurisci, Jordi Sebastià, Jana Patton-Vogt, Daniela Corda. Molecular characterization of a glycerophosphoinositol transporter in mammalian cells.
FEBS letters.
2006 Dec; 580(30):6789-96. doi:
10.1016/j.febslet.2006.11.039. [PMID: 17141226] - Claudia Almaguer, Edward Fisher, Jana Patton-Vogt. Posttranscriptional regulation of Git1p, the glycerophosphoinositol/glycerophosphocholine transporter of Saccharomyces cerevisiae.
Current genetics.
2006 Dec; 50(6):367-75. doi:
10.1007/s00294-006-0096-8. [PMID: 16924500] - Shunzhong Bao, Alan Bohrer, Sasanka Ramanadham, Wu Jin, Sheng Zhang, John Turk. Effects of stable suppression of Group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells.
The Journal of biological chemistry.
2006 Jan; 281(1):187-98. doi:
10.1074/jbc.m509105200. [PMID: 16286468] - Oleg O Glebov, Nicholas A Bright, Benjamin J Nichols. Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells.
Nature cell biology.
2006 Jan; 8(1):46-54. doi:
10.1038/ncb1342. [PMID: 16341206] - C Almaguer, D Mantella, E Perez, J Patton-Vogt. Inositol and phosphate regulate GIT1 transcription and glycerophosphoinositol incorporation in Saccharomyces cerevisiae.
Eukaryotic cell.
2003 Aug; 2(4):729-36. doi:
10.1128/ec.2.4.729-736.2003. [PMID: 12912892] - S S Nair, J Leitch, M L Garg. Suppression of inositol phosphate release by cardiac myocytes isolated from fish oil-fed pigs.
Molecular and cellular biochemistry.
2000 Dec; 215(1-2):57-64. doi:
10.1023/a:1026538932590. [PMID: 11204456] - M L Uhrig, A S Couto, W Colli, R M de Lederkremer. Characterization of inositolphospholipids in Trypanosoma cruzi trypomastigote forms.
Biochimica et biophysica acta.
1996 May; 1300(3):233-9. doi:
10.1016/0005-2760(96)00021-5. [PMID: 8679689] - U Leli, G Hauser. Chlorpromazine induces accumulation of inositol phosphates in C6 glioma cells.
Biochemical and biophysical research communications.
1986 Mar; 135(2):465-72. doi:
10.1016/0006-291x(86)90017-3. [PMID: 3008721]