Immepip (BioDeep_00001869490)

Main id: BioDeep_00000011971

 


代谢物信息卡片


4-(1h-imidazol-4-ylmethyl)-piperidine

化学式: C9H15N3 (165.1266)
中文名称: 4-(1H-咪唑-4-甲基)-哌啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CNCCC1CC2=CN=CN2
InChI: InChI=1S/C9H15N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h6-8,10H,1-5H2,(H,11,12)

描述信息

同义名列表

3 个代谢物同义名

4-(1h-imidazol-4-ylmethyl)-piperidine; Immepip; Immepip



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ANXA2, CA3, CACNA1A, CYP2D6, CYP3A4, DDC, HDC, MAP2, PRKX, S100A12
Peripheral membrane protein 1 S100A12
Endosome membrane 1 SLC6A4
Endoplasmic reticulum membrane 3 CYP2D6, CYP3A4, DRD1
Nucleus 6 ANXA2, CACNA1A, DRD1, HDC, PRKX, S100A12
cytosol 7 ANXA2, CA3, DDC, HDC, HRH1, MAP2, S100A12
dendrite 5 ADORA2A, HRH1, HRH3, HRH4, MAP2
nucleoplasm 1 PRKX
RNA polymerase II transcription regulator complex 1 ANXA2
Cell membrane 9 ADORA2A, CACNA1A, DRD1, GRID1, HRH1, HRH3, HRH4, S100A12, SLC6A4
Multi-pass membrane protein 8 ADORA2A, CACNA1A, CACNA1B, DRD1, GRID1, HRH1, HRH3, SLC6A4
Synapse 6 CACNA1A, CACNA1B, HRH1, HRH3, HRH4, SLC6A4
cell surface 1 ANXA2
dendritic shaft 1 MAP2
glutamatergic synapse 3 ADORA2A, DRD1, GRID1
lysosomal membrane 2 ANXA2, AP5B1
neuronal cell body 4 ADORA2A, CACNA1A, CACNA1B, MAP2
presynaptic membrane 3 ADORA2A, DRD1, SLC6A4
sarcolemma 1 ANXA2
Presynapse 2 HRH3, SLC6A4
endosome 1 ANXA2
plasma membrane 11 ADORA2A, ANXA2, CACNA1A, CACNA1B, DRD1, GRID1, HRH1, HRH3, HRH4, S100A12, SLC6A4
presynaptic active zone 1 ADORA2A
Membrane 8 ADORA2A, ANXA2, CACNA1A, CACNA1B, CYP2D6, CYP3A4, HDC, SLC6A4
basolateral plasma membrane 1 ANXA2
extracellular exosome 3 ANXA2, DDC, GRID1
endoplasmic reticulum 1 CYP2D6
extracellular space 1 ANXA2
adherens junction 1 ANXA2
mitochondrion 2 CYP2D6, HTN3
intracellular membrane-bounded organelle 2 CYP2D6, CYP3A4
Microsome membrane 2 CYP2D6, CYP3A4
Secreted 2 HTN3, S100A12
extracellular region 3 ANXA2, HTN3, S100A12
Single-pass membrane protein 1 CYP2D6
ciliary membrane 1 DRD1
dendritic spine 1 DRD1
midbody 1 ANXA2
Early endosome 1 ANXA2
vesicle 1 ANXA2
postsynaptic membrane 4 ADORA2A, DRD1, GRID1, SLC6A4
Membrane raft 1 SLC6A4
Cell junction, focal adhesion 1 SLC6A4
Cytoplasm, cytoskeleton 2 MAP2, S100A12
focal adhesion 1 SLC6A4
microtubule 1 MAP2
axolemma 1 ADORA2A
GABA-ergic synapse 2 DRD1, GRID1
basement membrane 1 ANXA2
Cell projection, dendritic spine 1 DRD1
collagen-containing extracellular matrix 1 ANXA2
intermediate filament 1 ADORA2A
Postsynaptic cell membrane 1 GRID1
dendrite cytoplasm 1 MAP2
Late endosome 1 AP5B1
Cell projection, neuron projection 1 SLC6A4
neuron projection 2 MAP2, SLC6A4
cilium 1 DRD1
microtubule associated complex 1 MAP2
Late endosome membrane 1 ANXA2
cell projection 1 CACNA1A
cytoskeleton 1 S100A12
plasma membrane protein complex 1 ANXA2
non-motile cilium 1 DRD1
Endomembrane system 1 SLC6A4
Lipid droplet 1 ANXA2
Cornified envelope 1 ANXA2
monoatomic ion channel complex 2 CACNA1A, CACNA1B
axon initial segment 1 MAP2
Cell projection, dendrite 2 DRD1, MAP2
Melanosome 1 ANXA2
dendritic growth cone 1 MAP2
secretory granule lumen 1 S100A12
nuclear matrix 1 ANXA2
voltage-gated calcium channel complex 2 CACNA1A, CACNA1B
proximal neuron projection 1 MAP2
Schmidt-Lanterman incisure 1 ANXA2
azurophil granule lumen 1 ANXA2
postsynaptic density membrane 1 GRID1
vesicle membrane 1 ANXA2
axon hillock 1 MAP2
basal dendrite 1 MAP2
AP-5 adaptor complex 1 AP5B1
AP-type membrane coat adaptor complex 1 AP5B1
Cell projection, cilium membrane 1 DRD1
Secreted, extracellular space, extracellular matrix, basement membrane 1 ANXA2
AnxA2-p11 complex 1 ANXA2
myelin sheath adaxonal region 1 ANXA2
PCSK9-AnxA2 complex 1 ANXA2
asymmetric synapse 1 ADORA2A
apical distal dendrite 1 MAP2
dendritic branch 1 MAP2
dendritic filopodium 1 MAP2
distal dendrite 1 MAP2
primary dendrite 1 MAP2
proximal dendrite 1 MAP2
G protein-coupled receptor complex 1 DRD1
[His3-(20-43)-peptide]: Secreted 1 HTN3
serotonergic synapse 1 SLC6A4


文献列表

  • Saara Nuutinen, Minnamaija Lintunen, Jenni Vanhanen, Tiia Ojala, Stanislav Rozov, Pertti Panula. Evidence for the role of histamine H3 receptor in alcohol consumption and alcohol reward in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2011 Sep; 36(10):2030-40. doi: 10.1038/npp.2011.90. [PMID: 21654737]
  • Parisa Hasanein. Effects of histamine H3 receptors on chemical hyperalgesia in diabetic rats. Neuropharmacology. 2011 May; 60(6):886-91. doi: 10.1016/j.neuropharm.2011.01.004. [PMID: 21237180]
  • Christian Brabant, Livia Alleva, Thierry Grisar, Etienne Quertemont, Bernard Lakaye, Hiroshi Ohtsu, Jian-Sheng Lin, Peter Jatlow, Marina R Picciotto, Ezio Tirelli. Effects of the H3 receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions. Psychopharmacology. 2009 Mar; 202(4):673-87. doi: 10.1007/s00213-008-1345-y. [PMID: 18843481]
  • Brendan A Gavin, Susan E Arruda, Patrick J Dolph. The role of carcinine in signaling at the Drosophila photoreceptor synapse. PLoS genetics. 2007 Dec; 3(12):e206. doi: 10.1371/journal.pgen.0030206. [PMID: 18069895]
  • Jacob Raber. Role of apolipoprotein E in anxiety. Neural plasticity. 2007; 2007(?):91236. doi: 10.1155/2007/91236. [PMID: 17710250]
  • Jingcai Chen, Changlu Liu, Timothy W Lovenberg. Molecular and pharmacological characterization of the mouse histamine H3 receptor. European journal of pharmacology. 2003 Apr; 467(1-3):57-65. doi: 10.1016/s0014-2999(03)01635-2. [PMID: 12706455]
  • Dirk Gründemann, Ann-Cathrin Koschker, Christine Haag, Cornelius Honold, Tim Zimmermann, Edgar Schömig. Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells. British journal of pharmacology. 2002 Nov; 137(6):910-8. doi: 10.1038/sj.bjp.0704926. [PMID: 12411423]
  • Y Zhu, D Michalovich, H Wu, K B Tan, G M Dytko, I J Mannan, R Boyce, J Alston, L A Tierney, X Li, N C Herrity, L Vawter, H M Sarau, R S Ames, C M Davenport, J P Hieble, S Wilson, D J Bergsma, L R Fitzgerald. Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Molecular pharmacology. 2001 Mar; 59(3):434-41. doi: 10.1124/mol.59.3.434. [PMID: 11179436]